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11. 发明申请

WO2009091862A2 COMPOSITIONS AND METHODS FOR THE SUPPRESSION OF TARGET POLYNUCLEOTIDES FROM LEPIDOPTERA 审中-公开
标题翻译：用于抑制来自LEPIDOPTERA的目标多核苷酸的组合物和方法
公开(公告)号：WO2009091862A2
公开(公告)日：2009-07-23
申请号：PCT/US2009031055
申请日：2009-01-15
申请人： PIONEER HI BRED INT , DU PONT , HERRMANN RAFAEL , LASSNER MICHAEL , LU ALBERT L , NELSON MARK , PRESNAIL JAMES K , RICE JANET A
发明人： HERRMANN RAFAEL , LASSNER MICHAEL , LU ALBERT L , NELSON MARK , PRESNAIL JAMES K , RICE JANET A
IPC分类号： C12N15/82
CPC分类号： C12N15/8286 , A01N65/20 , A01N65/44 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12N2310/531 , C12N2320/32 , Y02A40/162
摘要： Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a pest from the Lepidoptera order, they are capable of decreasing the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides target polynucleotides encoding polypeptides from specific protein families and various target polynucleotides set forth in SEQ ID NOS: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, or 50 or active variants and fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity). Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. In specific embodiment, the pest is Spodoptera frugiperda. Plants, plant part, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
摘要翻译：提供了使用沉积元件的方法和组合物，当沉积元件在被害虫如来自鳞翅目序列的害虫中摄取时，它们能够降低害虫中靶序列的表达。在具体实施方案中，靶序列的表达降低控制有害生物，因此方法和组合物能够限制对植物的损害。本发明提供编码来自特定蛋白质家族的多肽的多核苷酸和SEQ ID NO：1,2,3,4,5,6,7,8,9,10,11,12,13,14中所示的各种靶多核苷酸的靶多核苷酸，15，16，17，18，19，20，21，22，23，24，25，26，27，28，29，30，31，32，33，34，35，36，37，38，39 ，40,41,42,43,44,45,46,47,48,49或50个或其活性变体和片段，其中目标害虫中一个或多个序列的表达降低控制害虫（即，具有杀虫活性）。进一步提供的是沉积元件，当被害虫摄入时，降低靶多肽的水平，从而控制害虫。在具体实施方案中，害虫是草地夜蛾（Spodoptera frugiperda）。还提供了包含本发明的沉默元件或其活性变体或片段的植物，植物部分，细菌和其它宿主细胞。

12. 发明申请

WO2007061863A3 ELECTRONIC SURVEYING METHOD AND SYSTEM 审中-公开
标题翻译：电子测量方法与系统
公开(公告)号：WO2007061863A3
公开(公告)日：2009-04-30
申请号：PCT/US2006044710
申请日：2006-11-17
申请人： NELSON MARK
发明人： NELSON MARK
IPC分类号： G09B7/00
CPC分类号： G06Q30/00 , G09B7/02
摘要： The present invention provides a method for providing a survey to an individual by displaying a video, audio, or audio/video presentation and collecting responses to the information display. The survey responses are collected over duration of the presentation and can be displayed along with the information display in a synchronized fashion.
摘要翻译：本发明提供一种通过显示视频，音频或音频/视频呈现并且收集对信息显示的响应来向个人提供调查的方法。调查回答是在演示的持续时间内收集的，并且可以以同步的方式与信息显示一起显示。

13. 发明申请

WO2009091864A3 COMPOSITIONS AND METHODS FOR THE SUPPRESSION OF TARGET POLYNUCLEOTIDES FROM LYGUS 审中-公开
标题翻译：抑制淋巴瘤靶向多核苷酸的组合物和方法
公开(公告)号：WO2009091864A3
公开(公告)日：2009-12-10
申请号：PCT/US2009031057
申请日：2009-01-15
申请人： PIONEER HI BRED INT , DU PONT , HERRMANN RAFAEL , LASSNER MICHAEL , LU ALBERT L , NELSON MARK , PRESNAIL JAMES K , RICE JANET A
发明人： HERRMANN RAFAEL , LASSNER MICHAEL , LU ALBERT L , NELSON MARK , PRESNAIL JAMES K , RICE JANET A
IPC分类号： C12N15/82
CPC分类号： C12N15/8286 , A01N57/16 , C12N15/113 , C12N15/8218 , C12N2310/141 , C12N2310/531 , Y02A40/162
摘要： Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a pest from the Lygus genus, they are capable of decreasing the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides various target polynucleotides from specific polypeptide families as disclosed herein, and further provides target polynucleotides set forth in SEQ ID NOS:1-21 or active variants thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity). Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. In specific embodiment, the pest is Lygus Hesperus. Plants, plant part, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
摘要翻译：提供了使用沉默元件的方法和组合物，所述沉默元件当被有害生物如来自草盲蝽属的害虫摄入时，能够降低害虫中靶序列的表达。在具体的实施方案中，靶序列表达的降低控制害虫，并且由此该方法和组合物能够限制对植物的损害。本发明提供了来自本文公开的特定多肽家族的各种靶多核苷酸，并且还提供了SEQ ID NO：1-21中列出的靶多核苷酸或其活性变体，其中靶害虫中一个或多个序列的表达降低控制害虫（即具有杀虫活性）。进一步提供了沉默元件，其在被害虫摄入时降低靶多肽的水平并由此控制害虫。在具体的实施方案中，害虫是草盲蝽（Lygus Hesperus）。还提供了包含本发明的沉默元件或其活性变体或片段的植物，植物部分，细菌和其他宿主细胞。

14. 发明申请

WO2009091860A3 COMPOSITIONS AND METHODS FOR THE SUPPRESSION OF TARGET POLYNUCLEOTIDES FROM THE FAMILY APHIDIDAE 审中-公开
标题翻译：用于抑制来自家庭蚜虫目标多核苷酸的组合物和方法
公开(公告)号：WO2009091860A3
公开(公告)日：2009-11-05
申请号：PCT/US2009031053
申请日：2009-01-15
申请人： PIONEER HI BRED INT , DU PONT , HERRMANN RAFAEL , LASSNER MICHAEL , LU ALBERT L , NELSON MARK , PRESNAIL JAMES K , RICE JANET A
发明人： HERRMANN RAFAEL , LASSNER MICHAEL , LU ALBERT L , NELSON MARK , PRESNAIL JAMES K , RICE JANET A
IPC分类号： C12N15/82
CPC分类号： C12N15/8286 , C07K14/43563 , Y02A40/162
摘要： Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a pest from the Aphididae family, they are capable of decreasing the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides target polynucleotides for specific protein classes and also target polynucleotides as set forth in SEQ ID NOS:1, 2, 3, 4, 5, 6, 7, 8, 9, 10 or active variants or fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity). Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. In specific embodiment, the pest is Aphis glycines. Plants, plant part, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
摘要翻译：提供了使用沉默元件的方法和组合物，所述沉默元件当被有害生物例如来自蚜科的害虫摄取时，能够降低害虫中靶序列的表达。在具体的实施方案中，靶序列表达的降低控制害虫，并且由此该方法和组合物能够限制对植物的损害。本发明提供了特定蛋白质类别的靶多核苷酸以及如SEQ ID NO：1,2,3,4,5,6,7,8,9,10或其活性变体或片段所示的靶多核苷酸，其中a 目标害虫中一个或多个序列表达的减少控制了害虫（即，具有杀虫活性）。进一步提供了沉默元件，其在被害虫摄入时降低靶多肽的水平并由此控制害虫。在具体的实施方案中，害虫是蚜虫（Aphis）甘氨酸。还提供了包含本发明的沉默元件或其活性变体或片段的植物，植物部分，细菌和其他宿主细胞。

15. 发明申请

WO0041771A3 MARTIAL ARTS PHYSICAL INTERACTION DEVICE AND METHOD 审中-公开
标题翻译：武术物理交互设备和方法
公开(公告)号：WO0041771A3
公开(公告)日：2000-11-30
申请号：PCT/US0001134
申请日：2000-01-14
申请人： NELSON MARK
发明人： NELSON MARK
IPC分类号： A63B69/02 , A63B69/00 , A63B69/24 , A63B69/34
CPC分类号： A63B69/34 , A63B69/004 , A63B2208/12
摘要： A physical interaction device includes a controller (110) and one or more arms (102), such as a first arm (102) and a second arm (101). The first arm (102) is movably connected with a first support (104). The first arm includes a first flexible portion sized to physically interact with a first limb portion of a user of the device. The second arm (101) is movably connected with a second support (105). The second arm (101) includes a second flexible portion sized to physically interact with the first limb portion of the user and/or a second limb portion of the user. The controller (110) is linkable with the first arm (102), the second arm (101) and the pitch adjuster (402). The controller (110) is configured to adjust the angle of the first arm (102) and the second arm (101). The controller (110) is configured to selectively cause a first movement of the first flexible portion of the first arm (102). The controller (110) is configured to selectively cause a second movement of the second flexible portion of the second arm (101). The first movement of the first flexible portion of the first arm (102) serves to contact the first flexible portion of the first arm (102) with the user to physically imitate a first human strike toward the user. The second movement of the second flexible portion of the second arm (101) serves to contact the second flexible portion of the second arm (101) with the user to physically imitate a second human strike toward the user.
摘要翻译：物理相互作用装置包括控制器（110）和一个或多个臂（102），诸如第一臂（102）和第二臂（101）。第一臂（102）与第一支撑件（104）可移动地连接。第一臂包括尺寸适于物理地与设备的使用者的第一肢体部分相互作用的第一柔性部分。第二臂（101）与第二支撑件（105）可移动地连接。第二臂（101）包括尺寸设计成与用户的第一肢体部分和/或使用者的第二肢体部分物理地相互作用的第二柔性部分。控制器（110）可与第一臂（102），第二臂（101）和俯仰调节器（402）连接。控制器（110）被配置为调节第一臂（102）和第二臂（101）的角度。控制器（110）被配置为选择性地引起第一臂（102）的第一柔性部分的第一移动。控制器（110）被配置为选择性地引起第二臂（101）的第二柔性部分的第二移动。第一臂（102）的第一柔性部分的第一运动用于与使用者接触第一臂（102）的第一柔性部分，以物理地模仿朝向使用者的第一人行进。第二臂（101）的第二柔性部分的第二运动用于与使用者接触第二臂（101）的第二柔性部分，以物理地模拟朝向使用者的第二人类撞击。

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