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11. 发明授权

US07160258B2 Capsule and method for treating or diagnosing the intestinal tract 有权
标题翻译：胶囊和治疗或诊断肠道的方法
公开(公告)号：US07160258B2
公开(公告)日：2007-01-09
申请号：US09892404
申请日：2001-06-26
申请人： Mir A. Imran , Olivier K. Colliou , Ted W. Layman , Sharon L. Lake , Harm TenHoff , Timothy J. Hughes
发明人： Mir A. Imran , Olivier K. Colliou , Ted W. Layman , Sharon L. Lake , Harm TenHoff , Timothy J. Hughes
IPC分类号： A61B5/117 , A61B5/103 , A61B5/05
CPC分类号： A61M31/002 , A61B1/00016 , A61B1/00082 , A61B1/041 , A61B5/002 , A61B5/0084 , A61B5/01 , A61B5/036 , A61B5/0538 , A61B5/06 , A61B5/061 , A61B5/065 , A61B5/073 , A61B5/11 , A61B5/14503 , A61B5/14539 , A61B5/1459 , A61B5/42 , A61B5/4233 , A61B5/4255 , A61B5/4839 , A61B5/6801 , A61B5/6873 , A61B18/14 , A61B2018/00482 , A61B2018/00577 , A61B2018/00642 , A61B2018/00702 , A61B2018/00821 , A61B2562/162 , A61M5/172 , A61M5/1723 , A61N1/36007 , A61N1/37205
摘要： A device and method for mapping, diagnosing and treating the intestinal tract is provided using a capsule passing through the intestinal tract. Further, a capsule tracking system is provided for tracking a capsule's location along the length of an intestinal tract as various treatment and/or sensing modalities are employed. In one variation, an acoustic signal is used to determine the location of the capsule. A map of sensed information may be derived from the pass of a capsule. Capsules may be subsequently passed through to treat the intestinal tract at a determined location along its length. One variation uses an electrical stimulation capsule to treat and/or diagnose a condition in the intestinal tract.
摘要翻译：使用通过肠道的胶囊提供用于映射，诊断和治疗肠道的装置和方法。此外，提供了胶囊跟踪系统，用于沿着肠道长度跟踪胶囊的位置，因为采用各种治疗和/或感测方式。在一个变型中，使用声信号来确定胶囊的位置。感测信息的图可以从胶囊的通过导出。随后可以将胶囊通过以沿着其长度在确定的位置治疗肠道。一个变体使用电刺激胶囊来治疗和/或诊断肠道中的病症。

12. 发明申请

US20110046479A1 SYSTEM FOR MARKING A LOCATION FOR TREATMENT WITHIN THE GASTROINTESTINAL TRACT 有权
标题翻译：用于标记在胃肠道手术中治疗的位置的系统
公开(公告)号：US20110046479A1
公开(公告)日：2011-02-24
申请号：US12917446
申请日：2010-11-01
申请人： Mir A. Imran , Olivier K. Colliou , Ted W. Layman , Sharon L. Lake , Harm TenHoff , Timothy J. Hughes
发明人： Mir A. Imran , Olivier K. Colliou , Ted W. Layman , Sharon L. Lake , Harm TenHoff , Timothy J. Hughes
IPC分类号： A61M31/00 , A61B8/12
CPC分类号： A61M31/002 , A61B1/00016 , A61B1/00082 , A61B1/041 , A61B5/002 , A61B5/0084 , A61B5/01 , A61B5/036 , A61B5/0538 , A61B5/06 , A61B5/061 , A61B5/065 , A61B5/073 , A61B5/11 , A61B5/14503 , A61B5/14539 , A61B5/1459 , A61B5/42 , A61B5/4233 , A61B5/4255 , A61B5/4839 , A61B5/6801 , A61B5/6873 , A61B18/14 , A61B2018/00482 , A61B2018/00577 , A61B2018/00642 , A61B2018/00702 , A61B2018/00821 , A61B2562/162 , A61M5/172 , A61M5/1723 , A61N1/36007 , A61N1/37205
摘要： A device and method for mapping, diagnosing and treating the intestinal tract is provided using a capsule passing through the intestinal tract. Further, a capsule tracking system is provided for tracking a capsule's location along the length of an intestinal tract as various treatment and/or sensing modalities are employed. In one variation, an acoustic signal is used to determine the location of the capsule. A map of sensed information may be derived from the pass of a capsule. Capsules may be subsequently passed through to treat the intestinal tract at a determined location along its length. One variation uses an electrical stimulation capsule to treat and/or diagnose a condition in the intestinal tract.
摘要翻译：使用通过肠道的胶囊提供用于映射，诊断和治疗肠道的装置和方法。此外，提供了胶囊跟踪系统，用于沿着肠道长度跟踪胶囊的位置，因为采用各种治疗和/或感测方式。在一个变型中，使用声信号来确定胶囊的位置。感测信息的图可以从胶囊的通过导出。随后可以将胶囊通过以沿着其长度在确定的位置治疗肠道。一个变体使用电刺激胶囊来治疗和/或诊断肠道中的病症。

13. 发明授权

US07483754B2 Endoscopic instrument system for implanting a device in the stomach 有权
标题翻译：用于将装置植入胃内的内窥镜仪器系统
公开(公告)号：US07483754B2
公开(公告)日：2009-01-27
申请号：US11281234
申请日：2005-11-16
申请人： Mir A. Imran , Olivier K. Colliou , Ted W. Layman , Sharon L. Lake
发明人： Mir A. Imran , Olivier K. Colliou , Ted W. Layman , Sharon L. Lake
IPC分类号： A61N1/18
CPC分类号： A61B5/6882 , A61B5/4238 , A61B17/3421 , A61B17/3478 , A61B2017/00004 , A61B2017/00017 , A61B2017/00026 , A61B2017/00084 , A61B2017/00477 , A61B2017/306 , A61B2017/3488 , A61F5/0003 , A61M25/02 , A61M2025/0233 , A61M2025/028 , A61N1/0509 , A61N1/0517 , A61N1/36007 , A61N1/372 , G01N27/126 , G06F19/00
摘要： An endoscopic delivery system is provided to deliver a functional device through the esophagus and into the stomach where it is attached the stomach wall The endoscopic instruments attach or remove the attachment devices and functional devices from the stomach and may be used to assist in determining the optimal attachment location.
摘要翻译：提供内窥镜递送系统以将功能装置通过食道传递到胃中，其中胃壁附接在胃壁上。内窥镜器械将附接装置和功能装置从胃附接或移除，并且可用于帮助确定最佳附件位置。

14. 发明授权

US07107100B2 Aendoscopic instrument system@ 有权
公开(公告)号：US07107100B2
公开(公告)日：2006-09-12
申请号：US10291449
申请日：2002-11-07
申请人： Mir A. Imran , Olivier K. Colliou , Ted W. Layman , Sharon L. Lake
发明人： Mir A. Imran , Olivier K. Colliou , Ted W. Layman , Sharon L. Lake
IPC分类号： A61N1/18
CPC分类号： A61B5/6882 , A61B5/4238 , A61B17/3421 , A61B17/3478 , A61B2017/00004 , A61B2017/00017 , A61B2017/00026 , A61B2017/00084 , A61B2017/00477 , A61B2017/306 , A61B2017/3488 , A61F5/0003 , A61M25/02 , A61M2025/0233 , A61M2025/028 , A61N1/0509 , A61N1/0517 , A61N1/36007 , A61N1/372 , G01N27/126 , G06F19/00
摘要： A device, system and method for diagnosing and treating gastric disorders is provided. A functional device resides within the patient's stomach and is secured to the stomach wall by an attachment device. The functional device may be a sensor for sensing various parameters of the stomach or stomach environment, or may be a therapeutic delivery device. The functional device in one embodiment provides a device, system and method for gastric electrical stimulation where stimulating electrodes are secured to the wall of the stomach by the attachment device or otherwise. A preferred device includes: at least one stimulating electrode in electrical contact with the stomach wall; an electronics unit containing the electronic circuitry of the device; and an attachment mechanism for attaching the device to the stomach wall. The functional devices may be programmed to respond to sensed information or signals. An endoscopic delivery system delivers the functional device through the esophagus and into the stomach where it is attached the stomach wall. The endoscopic instruments attach or remove the attachment devices and functional devices from the stomach and may be used to assist in determining the optimal attachment location.

15. 发明授权

US07016735B2 Gastric anchor and method 失效
标题翻译：胃锚和方法
公开(公告)号：US07016735B2
公开(公告)日：2006-03-21
申请号：US10290788
申请日：2002-11-07
申请人： Mir A. Imran , Oliver K. Colliou , Ted W. Layman , Deepak R. Gandhi , Sharon L. Lake
发明人： Mir A. Imran , Oliver K. Colliou , Ted W. Layman , Deepak R. Gandhi , Sharon L. Lake
IPC分类号： A61N1/18
CPC分类号： A61B5/6882 , A61B5/4238 , A61B17/3421 , A61B17/3478 , A61B2017/00004 , A61B2017/00017 , A61B2017/00026 , A61B2017/00084 , A61B2017/00477 , A61B2017/306 , A61B2017/3488 , A61F5/0003 , A61M25/02 , A61M2025/0233 , A61M2025/028 , A61N1/0509 , A61N1/0517 , A61N1/36007 , A61N1/372 , G01N27/126 , G06F19/00
摘要： A device, system and method for diagnosing and treating gastric disorders is provided. A functional device resides within the patient's stomach and is secured to the stomach wall by an attachment device. The functional device may be a sensor for sensing various parameters of the stomach or stomach environment, or may be a therapeutic delivery device. The functional device in one embodiment provides a device, system and method for gastric electrical stimulation where stimulating electrodes are secured to the wall of the stomach by the attachment device or otherwise. A preferred device includes: at least one stimulating electrode in electrical contact with the stomach wall; an electronics unit containing the electronic circuitry of the device; and an attachment mechanism for attaching the device to the stomach wall. The functional devices may be programmed to respond to sensed information or signals. An endoscopic delivery system delivers the functional device through the esophagus and into the stomach where it is attached the stomach wall. The endoscopic instruments attach or remove the attachment devices and functional devices from the stomach and may be used to assist in determining the optimal attachment location.
摘要翻译：提供了用于诊断和治疗胃疾病的装置，系统和方法。功能装置位于患者的胃内，并通过附接装置固定到胃壁。功能装置可以是用于感测胃或胃环境的各种参数的传感器，或者可以是治疗递送装置。在一个实施例中的功能装置提供了用于胃电刺激的装置，系统和方法，其中刺激电极通过附接装置或其它方式固定到胃壁。优选的装置包括：与胃壁电接触的至少一个刺激电极; 包含该装置的电子电路的电子单元; 以及用于将装置附接到胃壁的附接机构。功能设备可以被编程为响应感测的信息或信号。内窥镜递送系统通过食管将功能装置输送到胃中，在胃附着胃壁。内窥镜器械将附接装置和功能装置从胃附接或移除，并且可以用于帮助确定最佳的附接位置。

16. 发明授权

US09668690B1 Submucosal gastric implant device and method 有权
公开(公告)号：US09668690B1
公开(公告)日：2017-06-06
申请号：US10109296
申请日：2002-03-26
申请人： Mir A. Imran , Olivier K. Colliou , Harm TenHoff , Kevin Nason , Ted W. Layman
发明人： Mir A. Imran , Olivier K. Colliou , Harm TenHoff , Kevin Nason , Ted W. Layman
IPC分类号： A61B5/05 , A61B5/00 , A61N1/05 , A61N1/36 , A61B17/30 , A61B17/00 , A61F5/00
CPC分类号： A61B5/4238 , A61B5/6882 , A61B2017/00004 , A61B2017/00017 , A61B2017/00026 , A61B2017/00084 , A61B2017/00269 , A61B2017/306 , A61F5/0003 , A61N1/0509 , A61N1/0517 , A61N1/36007
摘要： A device, system and method for diagnosing and treating gastric disorders is provided. A submucosal gastric implant device is placed within the submucosal layer of a patient's stomach wall. The device in one embodiment provides electrical stimulation of the stomach wall and may use multiple electrode pairs for sequential stimulation. The device may also have other functional aspects such as a sensor for sensing various parameters of the stomach or stomach environment, or a therapeutic delivery device. The implant may be programmed to respond to sensed information or signals. The device may be modular with a portion of the device accessible outside the stomach wall for removal and replacement. An endoscopic delivery system prepares and delivers the functional device through the esophagus and into the stomach where it is placed through an opening in the mucosa into the submucosal layer of the stomach wall. The endoscopic instruments may be used to prepare a cavity in the submucosal layer of the stomach wall and deliver the device to the prepared cavity and if appropriate close the opening in the mucosa.

17. 发明申请

US20100305656A1 Gastric Simulation Anchor and Method 审中-公开
标题翻译：胃模拟锚和方法
公开(公告)号：US20100305656A1
公开(公告)日：2010-12-02
申请号：US12795389
申请日：2010-06-07
申请人： Mir A. Imran , Olivier K. Colliou , Ted W. Layman
发明人： Mir A. Imran , Olivier K. Colliou , Ted W. Layman
IPC分类号： A61N1/05 , A61N1/36
CPC分类号： A61N1/36007 , A61B5/4238 , A61B5/6882 , A61B17/3421 , A61B17/3478 , A61B2017/00004 , A61B2017/00017 , A61B2017/00026 , A61B2017/00084 , A61B2017/00477 , A61B2017/306 , A61B2017/3488 , A61F5/0003 , A61M25/02 , A61M2025/0233 , A61M2025/028 , A61N1/0509 , A61N1/0517 , A61N1/372 , G01N27/126
摘要： A device, system and method for electrically stimulating the stomach is provided. A device system and method for attaching a stimulating device to the stomach wall is also provided.
摘要翻译：提供了用于电刺激胃的装置，系统和方法。还提供了一种用于将刺激装置附接到胃壁的装置系统和方法。

18. 发明授权

US07756582B2 Gastric stimulation anchor and method 失效
标题翻译：胃刺激锚和方法
公开(公告)号：US07756582B2
公开(公告)日：2010-07-13
申请号：US11256264
申请日：2005-10-21
申请人： Mir A. Imran , Olivier K. Colliou , Ted W. Layman
发明人： Mir A. Imran , Olivier K. Colliou , Ted W. Layman
IPC分类号： A61N1/18
CPC分类号： A61N1/36007 , A61B5/4238 , A61B5/6882 , A61B17/3421 , A61B17/3478 , A61B2017/00004 , A61B2017/00017 , A61B2017/00026 , A61B2017/00084 , A61B2017/00477 , A61B2017/306 , A61B2017/3488 , A61F5/0003 , A61M25/02 , A61M2025/0233 , A61M2025/028 , A61N1/0509 , A61N1/0517 , A61N1/372 , G01N27/126
摘要： A device, system and method for electrically stimulating the stomach is provided. A device system and method for attaching a stimulating device to the stomach wall is also provided.
摘要翻译：提供了用于电刺激胃的装置，系统和方法。还提供了一种用于将刺激装置附接到胃壁的装置系统和方法。

19. 发明授权

US07824347B2 System for marking a location for treatment within the gastrointestinal tract 有权
标题翻译：用于标记胃肠道内治疗位置的系统
公开(公告)号：US07824347B2
公开(公告)日：2010-11-02
申请号：US10427672
申请日：2003-05-01
申请人： Mir A. Imran , Oliver K. Colliou , Ted W. Layman , Sharon L. Lake , Harm Tenhoff , Timothy J. Hughes
发明人： Mir A. Imran , Oliver K. Colliou , Ted W. Layman , Sharon L. Lake , Harm Tenhoff , Timothy J. Hughes
IPC分类号： A61B5/103 , A61B5/117 , A61B7/00 , A61B5/00 , A61B5/04 , A61B5/05 , A61B6/00 , A61B8/00 , A61B8/14 , A61B1/00 , A61B1/04 , H04R25/00 , A61H1/00 , A61H1/02 , A61H5/00
CPC分类号： A61M31/002 , A61B1/00016 , A61B1/00082 , A61B1/041 , A61B5/002 , A61B5/0084 , A61B5/01 , A61B5/036 , A61B5/0538 , A61B5/06 , A61B5/061 , A61B5/065 , A61B5/073 , A61B5/11 , A61B5/14503 , A61B5/14539 , A61B5/1459 , A61B5/42 , A61B5/4233 , A61B5/4255 , A61B5/4839 , A61B5/6801 , A61B5/6873 , A61B18/14 , A61B2018/00482 , A61B2018/00577 , A61B2018/00642 , A61B2018/00702 , A61B2018/00821 , A61B2562/162 , A61M5/172 , A61M5/1723 , A61N1/36007 , A61N1/37205
摘要： A device and method for mapping, diagnosing and treating the intestinal tract is provided using a capsule passing through the intestinal tract. Further, a capsule tracking system is provided for tracking a capsule's location along the length of an intestinal tract as various treatment and/or sensing modalities are employed. In one variation, an acoustic signal is used to determine the location of the capsule. A map of sensed information may be derived from the pass of a capsule. Capsules may be subsequently passed through to treat the intestinal tract at a determined location along its length. One variation uses an electrical stimulation capsule to treat and/or diagnose a condition in the intestinal tract.
摘要翻译：使用通过肠道的胶囊提供用于映射，诊断和治疗肠道的装置和方法。此外，提供了胶囊跟踪系统，用于沿着肠道长度跟踪胶囊的位置，因为采用各种治疗和/或感测方式。在一个变型中，使用声信号来确定胶囊的位置。感测信息的图可以从胶囊的通过导出。随后可以将胶囊通过以沿着其长度在确定的位置治疗肠道。一个变体使用电刺激胶囊来治疗和/或诊断肠道中的病症。

20. 发明授权

US07076305B2 Gastric device and instrument system and method 失效
公开(公告)号：US07076305B2
公开(公告)日：2006-07-11
申请号：US10295115
申请日：2002-11-14
申请人： Mir A. Imran , Olivier K. Collion , Ted W. Layman , Sharon L. Lake
发明人： Mir A. Imran , Olivier K. Collion , Ted W. Layman , Sharon L. Lake
IPC分类号： A61N1/18
CPC分类号： A61B5/6882 , A61B5/4238 , A61B17/3421 , A61B17/3478 , A61B2017/00004 , A61B2017/00017 , A61B2017/00026 , A61B2017/00084 , A61B2017/00477 , A61B2017/306 , A61B2017/3488 , A61F5/0003 , A61M25/02 , A61M2025/0233 , A61M2025/028 , A61N1/0509 , A61N1/0517 , A61N1/36007 , A61N1/372 , G01N27/126 , G06F19/00
摘要： A device, system and method for diagnosing and treating gastric disorders is provided. A functional device resides within the patient's stomach and is secured to the stomach wall by an attachment device. The functional device may be a sensor for sensing various parameters of the stomach or stomach environment, or may be a therapeutic delivery device. The functional device in one embodiment provides a device, system and method for gastric electrical stimulation where stimulating electrodes are secured to the wall of the stomach by the attachment device or otherwise. A preferred device includes: at least one stimulating electrode in electrical contact with the stomach wall; an electronics unit containing the electronic circuitry of the device; and an attachment mechanism for attaching the device to the stomach wall. The functional devices may be programmed to respond to sensed information or signals. An endoscopic delivery system delivers the functional device through the esophagus and into the stomach where it is attached the stomach wall. The endoscopic instruments attach or remove the attachment devices and functional devices from the stomach and may be used to assist in determining the optimal attachment location.

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