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11. 发明申请

US20110087200A1 Method and Apparatus for Universal Improvement of Vision 失效
公开(公告)号：US20110087200A1
公开(公告)日：2011-04-14
申请号：US12968838
申请日：2010-12-15
申请人： Jonathan Grierson , David Lieberman
发明人： Jonathan Grierson , David Lieberman
IPC分类号： A61F9/01 , G02C7/04 , G06F17/50
CPC分类号： G02C7/047 , A61F2/14 , A61F9/00804 , A61F2009/00872 , A61F2009/0088 , A61F2240/002
摘要： “Universal improvement” of vision is achieved by effectively changing the shape of the anterior refracting surface of the cornea to an ideal “turtleback” shape, on which is imposed the necessary curvature adjustment to achieve correction of distance vision. In accordance with one embodiment, the cornea is actually formed to the turtleback shape through corneal surgery, preferably laser ablation surgery. In accordance with a second embodiment, a contact lens with the desired distance corrected ideal turtleback shape on its anterior surface is positioned over the cornea.

12. 发明授权

US07922323B2 Method and apparatus for improving vision 有权
标题翻译：改善视力的方法和装置
公开(公告)号：US07922323B2
公开(公告)日：2011-04-12
申请号：US10162941
申请日：2002-06-04
申请人： David Lieberman , Johnathan Grierson
发明人： David Lieberman , Johnathan Grierson
IPC分类号： G02C7/04
CPC分类号： A61F9/013 , A61B34/10 , A61F9/00804 , A61F9/00819 , A61F2009/00872 , A61F2009/00882
摘要： Methods and apparatus are disclosed for causing the optical center of the eye to align “HIGH point” of the anterior surface of the cornea. In accordance with one aspect of the invention relating to corneal ablation procedures, the HIGH point of the eye is used as the pole of a spherical surface which is fitted approximately to a portion of the anterior surface of the cornea within a “bounded region.” For corneal ablation procedures, the “bounded region” comprises a generally inverted-cup shaped region of the anterior surface of the eye bounded at its periphery by a plane which is substantially perpendicular to a local z-axis. During the operation local high points which project above the spherical surface are ablated. According to another aspect of the invention relating to radial keratotomy procedures, a pair of incisions in the plane of a “great circle” are formed in the cornea to weaken and flatten it. As used herein, a “great circle” is formed by a plane containing the HIGH point and parallel to the local z-axis. The “bounded region” for radial keratotomy procedures is defined absolutely in terms of a circle projected onto the corneal surface which is centered about an axis passing through the HIGH point and parallel to the z-axis.
摘要翻译：公开了使眼睛的光学中心对准角膜前表面的“高点”的方法和装置。根据涉及角膜消融过程的本发明的一个方面，眼睛的高点被用作球形表面的极点，该球形表面近似地装配在“有界区域”内的角膜前表面的一部分上。对于角膜消融程序，“有界区域”包括眼睛前表面的大致倒杯状的区域，其边缘在其周边被基本上垂直于局部z轴的平面限定。在操作过程中，突出高于球面的局部高点被消融。根据本发明涉及径向角膜切开手术的另一方面，在角膜中形成“大圆”平面中的一对切口，以削弱和平坦化。如本文所使用的，“大圆”由包含HIGH点并平行于局部z轴的平面形成。用于径向角膜切开术的“有界区域”绝对按照投射到角膜表面上的圆定义，该圆周围绕穿过高分辨率点并平行于z轴的轴线居中。

13. 发明申请

US20070263238A1 Automatic image quality control of marking processes 有权
标题翻译：自动图像质量控制标记过程
公开(公告)号：US20070263238A1
公开(公告)日：2007-11-15
申请号：US11432924
申请日：2006-05-12
申请人： David Lieberman , William Blitz , Michael Mongeon , Roger Triplett , John Moore
发明人： David Lieberman , William Blitz , Michael Mongeon , Roger Triplett , John Moore
IPC分类号： G06F15/00
CPC分类号： H04N1/00002 , H04N1/00005 , H04N1/00015 , H04N1/00034 , H04N1/00039 , H04N1/00045 , H04N1/0005 , H04N1/00063 , H04N1/00068 , H04N1/00087
摘要： A first series of control patches is printed with a first marking engine. A second series of control patches is printed with a second marking engine. Relative reflectance values of the patches printed with the first and second marking engines are measured with respective first and second engine response sensors. Based at least on a difference in the measured relative reflectance values of the control patches printed with the first and second marking engines, a relative engine to engine error is determined. The engine to engine error is decomposed into components. Based on the decomposition, adjustment of at least binary values of a digital image is determined so that print density of a first marking engine output substantially matches print density of a second marking engine output.
摘要翻译：第一系列控制补丁打印有第一个标记引擎。第二系列控制补丁用第二个标记引擎打印。用第一和第二引擎响应传感器测量用第一和第二标记引擎打印的贴片的相对反射率值。至少基于用第一和第二标记引擎打印的控制补丁的测量相对反射率值的差异，确定相对发动机与发动机误差。发动机发动机故障分解成部件。基于分解，确定数字图像的至少二进制值的调整，使得第一标记引擎输出的打印密度基本上匹配第二标记引擎输出的打印浓度。

14. 发明申请

US20060149069A1 Process for synthesising useful intermediates for the preparation of avss3 receptor antagonists 失效
标题翻译：用于合成用于制备avss3受体拮抗剂的有用中间体的方法
公开(公告)号：US20060149069A1
公开(公告)日：2006-07-06
申请号：US10547407
申请日：2004-03-04
申请人： Brian Bishop , Karel Marie Brands , Ian Cottrell , Cameron Cowden , Anthony Davies , Stephen Keen , David Lieberman , Gavin Stewart
发明人： Brian Bishop , Karel Marie Brands , Ian Cottrell , Cameron Cowden , Anthony Davies , Stephen Keen , David Lieberman , Gavin Stewart
IPC分类号： C07D471/02
CPC分类号： C07D239/34 , C07D405/04 , C07D471/04
摘要： The present invention relates to the synthesis of intermediates for the preparation of compounds of formula (A): wherein n is 2 or 3 and various salt forms of these compounds. The compounds of formula (A) are useful as ανβ3 receptor antagonists.
摘要翻译：本发明涉及用于制备式（A）化合物的中间体的合成：其中n为2或3，以及这些化合物的各种盐形式。式（A）的化合物可用作Alphanubeta3受体拮抗剂。

15. 发明申请

US20060087694A1 Tinted edge enhancement using harmonic halftones for the boundary pixels 有权
标题翻译：带边缘增强使用谐波半色调为边界像素
公开(公告)号：US20060087694A1
公开(公告)日：2006-04-27
申请号：US10973725
申请日：2004-10-26
申请人： Connie Purdum , Robert Loce , Beilei Xu , David Lieberman , Mark Gwaltney , Jon McElvain , Charles Hains
发明人： Connie Purdum , Robert Loce , Beilei Xu , David Lieberman , Mark Gwaltney , Jon McElvain , Charles Hains
IPC分类号： H04N1/405
CPC分类号： H04N1/4092 , H04N1/4058
摘要： Disclosed herein is an image processing method for producing enhanced halftone edges, particularly suited to those edges which only lie upon the background as apposed to those edges which abut other halftone screens. It utilizes a step of defining border pixels and a step of halftoning those border pixels in a different manner than the halftoning applied to the interior region of the tint or image segment. The preferred halftone for the border pixels will be related to the interior halftone by some number of common spatial frequency harmonics. Examples of common-harmonic screening for an edge include, but are not limited to: (a) same screen with different tone reproduction characteristics (boosted edge values); (b) same screen angles and frequencies with a different spot function, possibly phase shifted; (c) a dot screen whose frequency vectors can be generated by the frequency vectors of the interior screen; (d) a line screen whose frequency vectors can be generated by the frequency vectors of the interior screen. This generation process is directed to ensuring that the two screens will be “harmonically matched” where at least one of the fundamental frequency vectors and harmonics of the first screen will equal at least one of the fundamental frequency vectors and harmonics of the second screen.
摘要翻译：本文公开了一种用于生产增强的半色调边缘的图像处理方法，特别适合于仅靠在与其它半色调屏幕相邻的那些边缘上的背景的那些边缘。它利用定义边框像素的步骤和以与应用于色调或图像片段的内部区域的半色调不同的方式对这些边界像素进行半色调的步骤。边框像素的优选半色调将通过一些数量的共同空间频率谐波与内部半色调相关。用于边缘的共谐波筛选的示例包括但不限于：（a）具有不同色调再现特性（增强边缘值）的相同屏幕; （b）具有不同光点功能的相同屏幕角度和频率，可能相移; （c）可以通过内部画面的频率矢量生成频率矢量的点画面; （d）可以通过内部画面的频率矢量生成其频率矢量的行画面。该生成处理旨在确保两个屏幕将被“谐波匹配”，其中基本频率矢量和第一屏幕的谐波中的至少一个将等于第二屏幕的基本频率矢量和谐波中的至少一个。

16. 发明申请

US20130317678A1 VEHICULAR DUAL MODE MASTER/SLAVE INTERFACE 有权
标题翻译：车辆双模式主/从接口
公开(公告)号：US20130317678A1
公开(公告)日：2013-11-28
申请号：US13849655
申请日：2013-03-25
申请人： David Lieberman , Robert Turgeon , Byron Tietjen , Greg Gardella
发明人： David Lieberman , Robert Turgeon , Byron Tietjen , Greg Gardella
IPC分类号： G06F17/00
CPC分类号： G06F17/00 , B63B49/00 , G06F1/1632 , H04M1/6075 , H04M1/72533
摘要： A vehicular interface may include an electromechanical interface between a hand-held electronic device and subsystems on a vehicular bus or network. In selected embodiments the interface may operate in a “master mode” when a handheld device, such as a tablet computer or smart-phone, is not inserted therein. In this mode the interface may serve as a master controller and accesses and controls various subsystems on a vehicle (such as engine control subsystems, media controllers, navigation systems, sensors and transducers) as a master controller. In one embodiment, when a tablet device is inserted into the interface, the interface may automatically switch to “slave mode” in which it acts as an adapter or interface between the tablet device and the vehicular subsystems. In this mode of operation the user's exclusive interface is through the tablet computer and the tablet computer serves as the master controller for the system.
摘要翻译：车辆接口可以包括手持式电子设备与车辆总线或网络上的子系统之间的机电接口。在所选择的实施例中，当手持设备（例如平板电脑或智能电话）未插入其中时，接口可以以“主模式”操作。在这种模式下，接口可以用作主控制器，并且访问和控制作为主控制器的车辆上的各种子系统（例如发动机控制子系统，媒体控制器，导航系统，传感器和换能器）。在一个实施例中，当平板电脑设备插入接口时，界面可以自动切换到“从模式”，其中它作为平板设备和车辆子系统之间的适配器或接口。在这种操作模式下，用户的专用接口是通过平板电脑和平板电脑作为系统的主控制器。

17. 发明申请

US20060268225A1 Contact lens with shaped periphery 失效
标题翻译：隐形眼镜带有外形
公开(公告)号：US20060268225A1
公开(公告)日：2006-11-30
申请号：US10558509
申请日：2004-05-27
申请人： David Lieberman , Jonathan Grierson
发明人： David Lieberman , Jonathan Grierson
IPC分类号： G02C7/04
CPC分类号： G02C7/04
摘要： Eye measurements taken on a patient being fitted for contact lens will include a refraction test and an additional measurement representing corneal depth variation on the surface of an imaginary cylinder having the same diameter as the lens. This information then used during lens manufacture to produce lens in which the perimeter is not circular and does not lie in a plane, but which drops backwards towards the eye at appropriate points to produce a saddle-shaped perimeter.
摘要翻译：对于接受镜片安装的患者进行的眼睛测量将包括折射测试和表示具有与透镜相同直径的假想圆柱体的表面上的角膜深度变化的附加测量。然后在透镜制造期间使用该信息来制造其中周边不是圆形并且不位于平面中的透镜，但是在适当的点向后朝向眼睛向下倾斜以产生鞍形周长。

18. 发明申请

US20060189966A1 Method and system for improving vision 审中-公开
标题翻译：改善视力的方法和系统
公开(公告)号：US20060189966A1
公开(公告)日：2006-08-24
申请号：US10516833
申请日：2003-06-03
申请人： David Lieberman , Jonathan Grierson
发明人： David Lieberman , Jonathan Grierson
IPC分类号： A61F9/008 , A61B18/18 , A61B3/10
CPC分类号： A61F9/007 , A61B3/107 , A61F2/145 , A61F2/16 , A61F9/0017 , A61F9/008 , A61F9/00804 , A61F9/013 , A61F2009/00872 , A61F2009/00895
摘要： Methods and apparatus (610) are disclosed for diagnosing vision and improving vision in a manner which does not interfere with the natural shape of the cornea or its orientation relative to the remainder of the eye, but which changes its surface curvature appropriately to achieve the required correction of vision. The focus of the cornea (14) is adjusted so that different regions focus substantially to the same axis and preferably to substantially the same point on the axis. This can be accomplished by shaping the cornea (e.g. through ablation) or by applying an appropriate contact lens or other optical lens. In either case, correcting the central portions of the cornea should have a more significant effect on correcting focus scatter than correcting the more outward portions.
摘要翻译：公开了用于以不影响角膜的自然形状或其相对于眼睛的其余部分的取向的方式来诊断视力和改善视力的方法和装置（610），但是适当地改变其表面曲率以实现所需的视力矫正调节角膜（14）的焦点，使得不同的区域基本上集中在相同的轴线上，并且优选地基本上集中在轴上相同的点上。这可以通过使角膜（例如通过消融）成形或通过施加适当的隐形眼镜或其它光学透镜来实现。在任一情况下，校正角膜的中心部分应该对校正焦点散射具有比校正更多向外部分更显着的效果。

19. 发明申请

US20060152764A1 Systems and methods for controlling a tone reproduction curve using error diffusion 有权
标题翻译：使用误差扩散来控制色调再现曲线的系统和方法
公开(公告)号：US20060152764A1
公开(公告)日：2006-07-13
申请号：US11034057
申请日：2005-01-13
申请人： Robert Loce , Beilei Xu , Reiner Eschbach , David Lieberman
发明人： Robert Loce , Beilei Xu , Reiner Eschbach , David Lieberman
IPC分类号： H04N1/405
CPC分类号： H04N1/407 , H04N1/40068 , H04N1/4052
摘要： A method of adjusting a TRC of an image is provided. The method involves receiving an image at an input resolution, resampling the image to a processing resolution if the imput resolution and the processing resolution are not same, processing the image using rank-ordered error diffusion, and resampling the processed image to a desired output resolution for the image if the processing resolution and the output resolution are not same.
摘要翻译：提供了一种调整图像的TRC的方法。该方法包括以输入分辨率接收图像，如果输入分辨率和处理分辨率不相同，则将图像重新采样到处理分辨率，使用等级错误扩散处理图像，并将处理的图像重新采样到期望的输出分辨率对于图像，如果处理分辨率和输出分辨率不相同。

20. 发明授权

US07066125B2 Frost plug adapter assembly 有权
标题翻译：冰插头适配器组件
公开(公告)号：US07066125B2
公开(公告)日：2006-06-27
申请号：US11069956
申请日：2005-03-03
申请人： David Lieberman
发明人： David Lieberman
IPC分类号： F02N17/02
CPC分类号： F01P11/20 , F02B77/005
摘要： A frost plug adapter assembly having a locking mechanism that provides a positive capture through an existing frost plug aperture. A cylindrical body is engaged within a frost plug aperture and is maintained in place by a bolt, a locking element and a wing nut. The bolt is advantageously positioned through the cylindrical body with a bolt head at the outer end. The wing nut is screwed onto a threaded end of the bolt so that the wings engage channels of arms of the locking element to spread the arms until they contact an inner annulus of the frost plug aperture. The frost plug adapter assembly is also capable of providing access to engine fluid by providing channels through the inner end of the cylindrical body. The frost plug adapter assembly is easy to install and the locking mechanism prevents the assembly from falling out under severe conditions.
摘要翻译：具有锁定机构的霜塞适配器组件，其通过现有的霜塞孔提供正的捕获。圆柱体接合在霜塞孔内，并通过螺栓，锁定元件和翼形螺母保持在适当位置。螺栓有利地通过圆柱体定位，在外端具有螺栓头。翼形螺母被拧在螺栓的螺纹端上，使得翼接合锁定元件的臂的通道以扩展臂，直到它们接触霜塞孔的内环。霜塞适配器组件还能够通过提供通过圆筒体的内端的通道来提供对发动机流体的通路。霜塞适配器组件易于安装，并且锁定机构防止组件在恶劣条件下脱落。

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