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11. 发明申请

US20120034218A1 RBM3 in Colorectal Cancer Prognostics 有权
标题翻译： RBM3在结肠直肠癌预后中的作用
公开(公告)号：US20120034218A1
公开(公告)日：2012-02-09
申请号：US13210816
申请日：2011-08-16
申请人： Mathias Uhlen , Fredrik Pontén , Karin Jirström
发明人： Mathias Uhlen , Fredrik Pontén , Karin Jirström
IPC分类号： A61K39/395 , C12Q1/68 , C07K7/06 , A61K31/7068 , A61P35/00 , C07K14/47 , C40B30/04 , G01N33/566
CPC分类号： C07K16/18 , A61K31/7068 , A61K39/39533 , A61K45/06 , C07K14/4748 , C07K16/3038 , C07K2317/34 , C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/158 , G01N33/57407 , G01N33/57419 , A61K2300/00
摘要： The present invention provides means, such as a method, for determining whether a mammalian subject having a colorectal cancer belongs to a first or a second group, wherein the prognosis of subjects of the first group is better than the prognosis of subjects of the second group. The method comprises the steps of: evaluating an amount of RBM3 protein or RBM3 mRNA molecule in at least part of a sample earlier obtained from the subject and determining a sample value corresponding to the evaluated amount; comparing said sample value with a predetermined reference value; andif said sample value is higher than said reference value, concluding that the subject belongs to the first group; and if said sample value is lower than or equal to said reference value, concluding that the subject belongs to the second group.
摘要翻译：本发明提供了用于确定具有结肠直肠癌的哺乳动物受试者是否属于第一组或第二组的方法，例如方法，其中第一组受试者的预后优于第二组受试者的预后。该方法包括以下步骤：评估早期从受试者获得的样品的至少部分中的RBM3蛋白或RBM3 mRNA分子的量，并确定对应于评估量的样品值; 将所述样本值与预定参考值进行比较; 并且如果所述样本值高于所述参考值，则认定所述对象属于所述第一组; 并且如果所述样本值低于或等于所述参考值，则认定所述对象属于所述第二组。

12. 发明申请

US20120270956A1 USE OF PROTEIN SATB2 AS A MARKER FOR COLORECTAL CANCER 有权
公开(公告)号：US20120270956A1
公开(公告)日：2012-10-25
申请号：US13542723
申请日：2012-07-06
申请人： Mathias UHLÉN , Fredrik Pontén
发明人： Mathias UHLÉN , Fredrik Pontén
IPC分类号： A61K47/00 , A61P35/00
CPC分类号： G01N33/57419 , G01N2333/4703
摘要： The invention provides new methods, means and uses in connection with detection, characterization and prognosis of colo-rectal cancer, via the identification of the SATB2 protein as a marker for this cancer type.

13. 发明授权

US08067190B2 Use of protein SATB2 as a marker for colorectal cancer 有权
标题翻译：使用蛋白质SATB2作为结肠直肠癌的标志物
公开(公告)号：US08067190B2
公开(公告)日：2011-11-29
申请号：US12302248
申请日：2007-06-04
申请人： Mathias Uhlén , Fredrik Pontén
发明人： Mathias Uhlén , Fredrik Pontén
IPC分类号： G01N33/574 , G01N33/53
CPC分类号： G01N33/57419 , G01N2333/4703
摘要： The invention provides new methods, means and uses in connection with detection, characterization and prognosis of colo-rectal cancer, via the identification of the SATB2 protein as a marker for this cancer type.
摘要翻译：本发明通过鉴定SATB2蛋白作为该癌症类型的标志物，提供了与直肠癌的检测，表征和预后有关的新方法，手段和用途。

14. 发明授权

US11687642B2 System and method for identifying and authenticating counterfeiting articles 有权
公开(公告)号：US11687642B2
公开(公告)日：2023-06-27
申请号：US16660864
申请日：2019-10-23
申请人： Fredrik Pontén
发明人： Fredrik Pontén
IPC分类号： G06F21/00 , G06F21/44 , G06V30/224 , G06V10/75 , G06V20/80
CPC分类号： G06F21/44 , G06V10/75 , G06V20/80 , G06V30/224
摘要： A system and method for identifying and authenticating a counterfeit article using digital fingerprints are disclosed. The system comprises a server with a processor and memory, and a database. The memory is configured to store a set of modules executable by the processor. The set of modules include, but not limited to, a digital image acquisition module, a comparison module, and a decision module. The digital image acquisition module is configured to extract analog identification indicium of the article from one or more images. The comparison module is configured to compare analog identification indicium with actual analog identification indicium of the article. The decision module detects the authenticity of the article based on the comparison results. The system further comprises an anti-counterfeiting network verification system in communication with the server, configured to securely protect the actual analog identification indicium of the article from unauthorized access and other potential crimes.

15. 发明授权

US08337669B2 Apparatus for washing and dewatering pulp 有权
标题翻译：纸浆清洗和脱水设备
公开(公告)号：US08337669B2
公开(公告)日：2012-12-25
申请号：US12747594
申请日：2008-12-11
申请人： Fredrik Pontén , Johan Bylander , Jörgen Lundberg
发明人： Fredrik Pontén , Johan Bylander , Jörgen Lundberg
IPC分类号： D21F1/00
CPC分类号： D21D1/40 , D21C9/06 , D21C9/18 , D21F1/78
摘要： Apparatus for washing and dewatering pulp comprising rotatable press rolls including permeable outer surfaces and a casing comprising a vat in which the rolls are installed are disclosed. A feed for feeding the pulp through the gap between the vat and the outer surfaces of the press rolls is provided and the vat includes a vat segment providing at least one compartment between the vat segment and the casing, the at least one compartment extending along the longitudinal extension of one of the first and second rotatable press rolls and a pressure device to maintain the pressure in the at least one compartment corresponding to the pressure in the gap.
摘要翻译：公开了用于洗涤和脱水纸浆的设备，其包括包括可渗透外表面的可旋转压榨辊和包括其中安装有辊的桶的壳体。提供了用于通过压榨辊和桶的外表面之间的间隙进给纸浆的进料，并且所述槽包括槽区段，其在槽段和壳体之间提供至少一个室，所述至少一个隔室沿着所述第一和第二可旋转压榨辊中的一个的纵向延伸部和压力装置，以保持所述至少一个隔室中的压力对应于所述间隙中的压力。

16. 发明申请

US20100269997A1 APPARATUS FOR WASHING AND DEWATERING PULP 有权
标题翻译：洗衣和清洁纸浆装置
公开(公告)号：US20100269997A1
公开(公告)日：2010-10-28
申请号：US12747568
申请日：2008-12-11
申请人： Johan Bylander , Fredrik Pontén , Jörgen Lundberg
发明人： Johan Bylander , Fredrik Pontén , Jörgen Lundberg
IPC分类号： D21F3/08
CPC分类号： D21F1/78 , B30B9/20 , D21C9/06 , D21C9/18 , D21D1/40
摘要： Apparatus for washing and dewatering pulp including a pair of rotatable press rolls with a permeable outer surface in a casing including a vat in which the press rolls are installed is provided. A gap is provided between the vat and the press rolls as well as means for feeding the pulp into the gap between the rolls and the vat includes a first segment partially enclosing the first roll and a second segment partially enclosing the second roll, and casing members for each segment are pivotable about axes of rotation to open and close the casing, and the distance between the axes of rotation is less than the sum of the outer diameter of the two press rolls.
摘要翻译：提供了一种用于洗涤和脱水纸浆的设备，其包括一对可旋转的压榨辊，其具有在包括其中安装有压榨辊的桶的壳体中的可渗透外表面。在槽和压榨辊之间提供间隙以及用于将纸浆输送到辊之间的间隙的装置，并且槽包括部分地包围第一辊的第一段和部分地包围第二辊的第二段，以及壳体构件对于每个段可以围绕旋转轴线枢转以打开和关闭壳体，并且旋转轴线之间的距离小于两个压辊的外径之和。

17. 发明授权

US08187425B2 Apparatus for washing and dewatering pulp 有权
标题翻译：纸浆清洗和脱水设备
公开(公告)号：US08187425B2
公开(公告)日：2012-05-29
申请号：US12747568
申请日：2008-12-11
申请人： Johan Bylander , Fredrik Pontén , Jörgen Lundberg
发明人： Johan Bylander , Fredrik Pontén , Jörgen Lundberg
IPC分类号： D21F1/00 , B30B9/06
CPC分类号： D21F1/78 , B30B9/20 , D21C9/06 , D21C9/18 , D21D1/40
摘要： Apparatus for washing and dewatering pulp including a pair of rotatable press rolls with a permeable outer surface in a casing including a vat in which the press rolls are installed is provided. A gap is provided between the vat and the press rolls as well as means for feeding the pulp into the gap between the rolls and the vat includes a first segment partially enclosing the first roll and a second segment partially enclosing the second roll, and casing members for each segment are pivotable about axes of rotation to open and close the casing, and the distance between the axes of rotation is less than the sum of the outer diameter of the two press rolls.
摘要翻译：提供了一种用于洗涤和脱水纸浆的设备，其包括一对可旋转的压榨辊，其具有在包括其中安装有压榨辊的桶的壳体中的可渗透外表面。在槽和压榨辊之间提供间隙以及用于将纸浆输送到辊之间的间隙的装置，并且槽包括部分地包围第一辊的第一段和部分地包围第二辊的第二段，以及壳体构件对于每个段可以围绕旋转轴线枢转以打开和关闭壳体，并且旋转轴线之间的距离小于两个压辊的外径之和。

18. 发明申请

US20100294708A1 APPARATUS FOR WASHING AND DEWATERING PULP 有权
标题翻译：洗衣和清洁纸浆装置
公开(公告)号：US20100294708A1
公开(公告)日：2010-11-25
申请号：US12747594
申请日：2008-12-11
申请人： Fredrik Pontén , Johan Bylander , Jörgen Lundberg
发明人： Fredrik Pontén , Johan Bylander , Jörgen Lundberg
IPC分类号： B01D33/64
CPC分类号： D21D1/40 , D21C9/06 , D21C9/18 , D21F1/78
摘要： Apparatus for washing and dewatering pulp comprising rotatable press rolls including permeable outer surfaces and a casing comprising a vat in which the rolls are installed are disclosed. A feed for feeding the pulp through the gap between the vat and the outer surfaces of the press rolls is provided and the vat includes a vat segment providing at least one compartment between the vat segment and the casing, the at least one compartment extending along the longitudinal extension of one of the first and second rotatable press rolls and a pressure device to maintain the pressure in the at least one compartment corresponding to the pressure in the gap.
摘要翻译：公开了用于洗涤和脱水纸浆的设备，其包括包括可渗透外表面的可旋转压榨辊和包括其中安装有辊的桶的壳体。提供了用于通过压榨辊和桶的外表面之间的间隙进给纸浆的进料，并且所述槽包括槽区段，其在槽段和壳体之间提供至少一个室，所述至少一个隔室沿着所述第一和第二可旋转压榨辊中的一个的纵向延伸部和压力装置，以保持所述至少一个隔室中的压力对应于所述间隙中的压力。

19. 发明授权

US08808499B2 Apparatus for washing and dewatering pulp, a system for controlling such an apparatus, and a method for processing pulp in such an apparatus 有权
标题翻译：纸浆清洗和脱水设备，用于控制这种设备的系统以及在这种设备中处理纸浆的方法
公开(公告)号：US08808499B2
公开(公告)日：2014-08-19
申请号：US12747648
申请日：2008-12-11
申请人： Johan Bylander , Fredrik Pontén , Rickard Andersson , Magnus Danielsson
发明人： Johan Bylander , Fredrik Pontén , Rickard Andersson , Magnus Danielsson
IPC分类号： D21C1/02 , D21D1/40 , D21C9/06 , D21C9/18 , D21F1/66
CPC分类号： D21C9/18 , B30B9/20 , D21C9/02 , D21C9/06 , D21D1/40 , D21F1/66
摘要： Methods for processing pulp in an apparatus for washing and dewatering pulp and a system for controlling this apparatus are provided. The apparatus includes a pair of rotatable press rolls installed in vats and including a press nip therebetween, an inlet for feeding the pulp to the press nip, with one of the press rolls being movable in relation to the other and in which the processing of the pulp is determined by the number of variable operating parameters. The method includes utilizing the distance between the press rolls as a variable operating parameter, setting a desired value for a specific control parameter, measuring the specific control parameter, and adjusting at least two of the variable operating parameters during operation to maintain the difference between the desired value and the measured value of the specific control parameter below a predetermined difference. Systems for controlling this apparatus are also disclosed.
摘要翻译：提供了一种用于在用于洗涤和脱水纸浆的设备中处理纸浆的方法和用于控制该设备的系统。该装置包括一对安装在大桶中的可旋转的压榨辊并且包括其间的压榨压区，用于将纸浆输送到压榨压区的入口，其中一个压榨辊相对于另一个可移动，并且其中纸浆由可变操作参数的数量决定。该方法包括利用压辊之间的距离作为可变操作参数，为特定控制参数设置期望值，测量特定控制参数，以及在操作期间调整至少两个可变操作参数以维持期望值和特定控制参数的测量值低于预定差值。还公开了用于控制该装置的系统。

20. 发明申请

US20110017646A1 Apparatus For Washing And Dewatering Pulp 有权
标题翻译：洗涤和脱水纸浆设备
公开(公告)号：US20110017646A1
公开(公告)日：2011-01-27
申请号：US12747683
申请日：2008-12-11
申请人： Johan Bylander , Fredrik Pontén , Jörgen Lundberg
发明人： Johan Bylander , Fredrik Pontén , Jörgen Lundberg
IPC分类号： D21C9/18 , B01D33/06 , B01D35/157 , D21C9/06
CPC分类号： D21D1/40 , B30B9/20 , D21C9/06 , D21C9/18 , D21F1/78
摘要： Apparatus for washing and dewatering pump comprising a pair of rotatable press rolls with permeable outer surfaces, a casing comprising a vat in which the rolls are installed, and a feed for feeding the pulp to the gap formed between the vat and the press roll is disclosed. The vat includes a first side vat segment partially enclosing the first press roll and a second side vat segment partially enclosing the second press roll and casing members for each of the vat segments, the first casing member being pivotable about an axis of rotation and between closed and open positions, pulp distribution devices for distributing pulp onto the press rolls, at least one of the pulp distribution devices being mounted on the casing member whereby it is moved away from the press roll together with the casing member when it is opened.
摘要翻译：公开了一种用于洗涤和脱水泵的设备，其包括一对具有可渗透外表面的可旋转的压榨辊，包括一个包括其中安装有辊的槽的壳体和用于将纸浆输送到形成于槽和压榨辊之间的间隙的进料。所述槽包括部分地包围所述第一压榨辊的第一侧槽段和部分地包围所述第二压榨辊的第二侧槽段和用于每个所述槽段的壳体构件，所述第一壳体构件围绕旋转轴线可旋转并且在闭合和开放位置，用于将纸浆分配到压榨辊上的纸浆分配装置，至少一个纸浆分配装置安装在壳体部件上，从而当纸张分配装置打开时与壳体部件一起移动。

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