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11. 发明申请

WO2022076913A1 LOW ENERGY MULTIMODAL STIMULATION 审中-公开
公开(公告)号：WO2022076913A1
公开(公告)日：2022-04-14
申请号：PCT/US2021/054306
申请日：2021-10-08
申请人： MEDTRONIC, INC.
发明人： CLELAND, Andrew J. , KELLEY, Brooke G. , HINCAPIE, Juan G. , SHARMA, Vinod , KRAMER, Jeffery M.
IPC分类号： A61N1/36 , A61B5/05
摘要： This disclosure is directed to devices, systems, and techniques for delivering various stimulation patterns. In some examples, a method includes generating, by stimulation generation circuitry, a first train of electrical stimulation pulses at a first frequency to a first target tissue, and generating, by the stimulation generation circuitry, a second train of electrical stimulation pulses at a second frequency to a second target tissue different from the first target tissue, wherein at least some electrical stimulation pulses of the first train of electrical stimulation pulses are interleaved with at least some electrical stimulation pulses of the second train of electrical stimulation pulses, and wherein the first frequency is greater than the second frequency.

12. 发明申请

WO2021113592A1 INTERVENTION FOR HEART FAILURE MANAGEMENT 审中-公开
公开(公告)号：WO2021113592A1
公开(公告)日：2021-06-10
申请号：PCT/US2020/063239
申请日：2020-12-04
申请人： MEDTRONIC, INC.
发明人： SHARMA, Vinod , WARMAN, Eduardo N.
IPC分类号： A61B5/00
摘要： A method for heart failure management may include volume overload intervention in response to sensor-based parameters indicating volume overload. The method may include administering non-volume overload intervention in response to the sensor-based parameters not indicating volume overload. Volume overload may be determined based on monitoring sensor-based parameters. Sensor-based parameters may be monitored in response to receiving an alert indicative of a worsening heart failure score or status for a patient.

13. 发明申请

WO2021055073A1 AUTOMATIC DETECTION OF BODY PLANES OF ROTATION 审中-公开
公开(公告)号：WO2021055073A1
公开(公告)日：2021-03-25
申请号：PCT/US2020/040084
申请日：2020-06-29
申请人： MEDTRONIC, INC.
发明人： RADTKE, Andrew , HADDAD, Tarek D. , GALARNEAU, Michelle M. , SHARMA, Vinod , WILKINSON, Jeffrey D. , LEE, Brian B. , WARMAN, Eduardo N.
IPC分类号： A61B5/00 , A61B5/11
摘要： Techniques are disclosed for automatically calibrating a reference orientation of an implantable medical device (IMD) within a patient. In one example, sensors of an IMD sense a plurality of orientation vectors of the IMD with respect to a gravitational field. Processing circuitry of the IMD processes the plurality of orientation vectors to identify an upright vector that corresponds to an upright posture of the patient. The processing circuitry classifies the plurality of orientation vectors with respect to the upright vector to define a sagittal plane of the patient and a transverse plane of the patient. The processing circuitry determines, based on the upright vector, the sagittal plane, and the transverse plane, a reference orientation of the IMD within the patient. As the orientation of the IMD within the patient changes over time, the processing circuitry may recalibrate its reference orientation and accurately detect a posture of the patient.

14. 发明申请

WO2020243061A1 MEDICAL DEVICE FOR FALL DETECTION 审中-公开
公开(公告)号：WO2020243061A1
公开(公告)日：2020-12-03
申请号：PCT/US2020/034485
申请日：2020-05-26
申请人： MEDTRONIC, INC.
发明人： GALARNEAU, Michelle M. , LEE, Brian B. , SHARMA, Vinod , RADTKE, Andrew
IPC分类号： A61B5/00 , A61B5/11
摘要： A medical device is configured to produce an accelerometer signal and detect a patient fall from the accelerometer signal. The device generates a body posture signal and a body acceleration signal from the accelerometer signal and detects a patient fall in response to determining that the body posture signal and the body acceleration signal meet fall detection criteria. The medical device is configured to receive a truth signal from another device that is not the medical device. The truth signal may indicate that the detected patient fall is a falsely detected patient fall and, responsive to receiving the truth signal, the medical device adjusts at least one fall detection control parameter.

15. 发明申请

WO2019210095A1 MEDICAL SYSTEM FOR THERAPY ADJUSTMENT 审中-公开
公开(公告)号：WO2019210095A1
公开(公告)日：2019-10-31
申请号：PCT/US2019/029193
申请日：2019-04-25
申请人： MEDTRONIC, INC.
发明人： SHARMA, Vinod
IPC分类号： A61B5/02 , A61B5/04 , H04W4/80
摘要： Methods and systems for seamless adjustment of treatment are disclosed. A determination can be made as to whether to intervene with a patient's treatment based on data obtained from implantable electrodes and/or non-implantable electrodes. The data from non-implantable electrodes have a correction factor applied to adjust for less accuracy compared to data acquired from implantable electrodes.

16. 发明申请

WO2015164167A1 IMPLANTABLE MEDICAL DEVICE (IMD) SENSING MODIFICATIONS RESPONSIVE TO DETECTED PACING PULSES 审中-公开
标题翻译：植入式医疗设备（IMD）对检测到的皮肤脉搏的感觉改变
公开(公告)号：WO2015164167A1
公开(公告)日：2015-10-29
申请号：PCT/US2015/026094
申请日：2015-04-16
申请人： MEDTRONIC, INC.
发明人： REINKE, James D. , ZHANG, Xusheng , SHARMA, Vinod , NIKOLSKI, Vladimir P. , TERRY, Michael B. , HARELAND, Scott A. , HANSEN, Daniel L. , SALMI, Donna M.
IPC分类号： A61N1/37
CPC分类号： A61B5/0464 , A61B5/04017 , A61B5/686 , A61N1/3702
摘要： In situations in which an implantable medical device (IMD) (e.g., an extravascular ICD) is co-implanted with a leadless pacing device (LPD), it may be important that the IMD knows when the LPD is delivering pacing, such as anti-tachycardia pacing (ATP). Techniques are described herein for detecting, with the IMD and based on the sensed electrical signal, pacing pulses and adjusting operation to account for the detected pulses, e.g., blanking the sensed electrical signal or modifying a tachyarrhythmia detection algorithm. In one example, the IMD includes a pace pulse detector that detects, based on the processing of sensed electrical signals, delivery of a pacing pulse from a second implantable medical device and blank, based on the detection of the pacing pulse, the sensed electrical signal to remove the pacing pulse from the sensed electrical signal.
摘要翻译：在可植入医疗器械（IMD）（例如，血管外ICD））与无引线起搏器（LPD）共同植入的情况下，IMD知道LPD何时发出起搏，心动过速起搏（ATP）。本文描述了技术，用于利用IMD并基于感测的电信号来检测起搏脉冲和调整操作以解决检测到的脉冲，例如消隐感测的电信号或修改快速性心律失常检测算法。在一个示例中，IMD包括步速脉冲检测器，其基于感测到的电信号的处理，基于起搏脉冲的检测来检测来自第二可植入医疗设备和空白的起搏脉冲，检测到的电信号以从所感测的电信号中去除起搏脉冲。

17. 发明申请

WO2003092792A2 COMBINED ANTI-TACHYCARDIA PACING (ATP) AND HIGH VOLTAGE THERAPY FOR TREATING VENTRICULAR ARRHYTHMIAS 审中-公开
标题翻译：联合抗惊厥药（ATP）和高电压治疗心室性心律失常
公开(公告)号：WO2003092792A2
公开(公告)日：2003-11-13
申请号：PCT/US2003/007373
申请日：2003-03-10
申请人： MEDTRONIC, INC.
发明人： OUSDIGIAN, Kevin, T. , PADMANABHAN, Vasant , DEGROOT, Paul, J. , SHARMA, Vinod , KASZAS, Cameron, J. , KRAUSE, Paul, G. , OLSON, Walter, H.
IPC分类号： A61N
CPC分类号： A61N1/3962 , A61N1/3987
摘要： The present invention provides a system and method for treating an arrhythmia of the heart. The system and method involves delivery of anti-tachy pacing (ATP) pulses to the heart, possibly followed by the delivery of a high-voltage shock. ATP delivery is controlled such that the time of delivery of any high-voltage shock is not affected by the prior delivery of the ATP pulses. System control may be accomplished using one or more programmable parameters, which may include a user-specified shock energy.
摘要翻译：本发明提供了用于治疗心脏心律失常的系统和方法。该系统和方法包括向心脏递送抗起搏起搏（ATP）脉冲，可能之后传送高压电击。控制ATP递送，使得任何高压休克的递送时间不受先前递送ATP脉冲的影响。系统控制可以使用一个或多个可编程参数来实现，其可以包括用户指定的冲击能量。

18. 发明申请

WO2023034122A1 CARDIAC AND TEMPERATURE MONITOR 审中-公开
公开(公告)号：WO2023034122A1
公开(公告)日：2023-03-09
申请号：PCT/US2022/041563
申请日：2022-08-25
申请人： MEDTRONIC, INC.
发明人： SHRIVASTAV, Maneesh , MUSLEY, Shailesh Kumar V. , SHARMA, Vinod
IPC分类号： G16H50/20 , G16H50/30 , G16H40/63 , G16H10/60 , A61B5/00 , A61B5/349
摘要： A medical system including processing circuitry configured to assess a blood glucose level of a patient. The processing circuitry is configured to use a cardiac signal indicative of the electrical activity of the patient's heart and a temperature signal indicative of a body temperature of the patient. The cardiac signal may be, for example, an electrocardiogram (ECG), an electrogram (EGM), or another measure. The medical system is configured to determine a representative cardiac measure indicative of the cardiac signal and determine a representative temperature measure indicative of the temperature signal. The medical system is configured to assess when a blood glucose level of the patient may be outside a euglycemic range based on the representative cardiac measure and the representative temperature measure determined.

19. 发明申请

WO2022183194A1 NEUROSTIMULATION TITRATION SYSTEM 审中-公开
公开(公告)号：WO2022183194A1
公开(公告)日：2022-09-01
申请号：PCT/US2022/070805
申请日：2022-02-24
申请人： MEDTRONIC, INC.
发明人： SHARMA, Vinod , CLELAND, Andrew J. , TORGERSON, Nathan A.
IPC分类号： A61N1/36 , A61N1/372 , A61N1/05
摘要： An example system includes electrodes configured to deliver the electrical stimulation to a patient, and a device comprising processing circuitry configured to determine, for a patient, a loading dose of electric stimulation. The processing circuitry is also configured to cause electrical stimulation circuitry' to deliver, during a first time period, the loading dose to the patient, receive patient feedback representing a response of the patient to the loading dose, determine, based on patient feedback, a maintenance dose of electrical stimulation, and cause the electrical stimulation circuitry to deliver, and during a second time period that is after the first time period, a maintenance dose of electrical stimulation. Delivering the maintenance dose of electrical stimulation consumes less power than delivering the loading dose of electrical stimulation.

20. 发明申请

WO2015164172A1 PACE PULSE DETECTOR FOR AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：用于可植入医疗装置的脉冲检测器
公开(公告)号：WO2015164172A1
公开(公告)日：2015-10-29
申请号：PCT/US2015/026107
申请日：2015-04-16
申请人： MEDTRONIC, INC.
发明人： REINKE, James D. , ZHANG, Xusheng , SHARMA, Vinod , NIKOLSKI, Vladimir P. , TERRY, Michael B. , HARELAND, Scott A. , HANSEN, Daniel L. , SALMI, Donna M.
IPC分类号： A61N1/39 , A61B5/04
CPC分类号： A61B5/0464 , A61B5/04017 , A61B5/686 , A61N1/371 , A61N1/3962
摘要： In situations in which an implantable medical device (e.g., a subcutaneous ICD) is co-implanted with a leadless pacing device (LPD), it may be important that the subcutaneous ICD knows when the LPD is delivering pacing, such as anti-tachycardia pacing (ATP). Techniques are described herein for detecting, with the ICD and based on the sensed electrical signal, pacing pulses and adjusting operation to account for the detected pulses, e.g., blanking the sensed electrical signal or modifying a tachyarrhythmia detection algorithm. In one example, the ICD includes a first pace pulse detector configured to obtain a sensed electrical signal and analyze the sensed electrical signal to detect a first type of pulses having a first set of characteristics and a second pace pulse detector configured to obtain the sensed electrical signal and analyze the sensed electrical signal to detect a second type of pulses having a second set of characteristics.
摘要翻译：在可植入医疗器械（例如皮下ICD）与无引线起搏器（LPD）共同植入的情况下，皮下ICD知道LPD何时发出起搏，例如抗心动过速起搏（ATP）。本文描述了用于利用ICD并基于所感测到的电信号，用于检测起搏脉冲和调整操作以考虑检测到的脉冲的技术，例如消隐感测的电信号或修改快速性心律失常检测算法。在一个示例中，ICD包括第一速度脉冲检测器，其被配置为获得感测的电信号并且分析所感测的电信号以检测具有第一组特性的第一类型的脉冲和被构造成获得感测的电信号并分析所感测的电信号以检测具有第二组特性的第二类型的脉冲。

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