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11. 发明申请

WO2015055473A1 MEDICAL APPARATUS WITH A RADIATION THERAPY DEVICE AND A RADIATION DETECTION SYSTEM 审中-公开
标题翻译：具有放射治疗装置和辐射检测系统的医疗装置
公开(公告)号：WO2015055473A1
公开(公告)日：2015-04-23
申请号：PCT/EP2014/071485
申请日：2014-10-08
申请人： KONINKLIJKE PHILIPS N.V.
发明人： VAHALA, Erkki Tapani , AMTHOR, Thomas Erik , FORTHMANN, Peter
IPC分类号： A61N5/10
CPC分类号： A61N5/1049 , A61B2090/374 , A61B2090/3954 , A61N5/1038 , A61N5/1039 , A61N5/1047 , A61N5/1067 , A61N5/1075 , A61N5/1081 , A61N2005/1052 , A61N2005/1054 , A61N2005/1055 , A61N2005/1059
摘要： The invention provides for a medical apparatus (100, 300, 400, 800) comprising a magnetic resonance imaging system (104), a radiation therapy device (102) comprising a gantry (106) and a radiation source (110), and a radiation detection system (102) operable for measuring radiation detection data (174) descriptive of the path and intensity of the radiation beam at the intersection of the radiation beam with at least one surface (144, 144', 144") surrounding the subject using at least one radiation detector (144, 144', 144"). Execution of machine readable instructions causes a processor controlling the medical apparatus to: receive (200) a treatment plan (168), acquire (202) magnetic resonance data (164) from the imaging zone using the magnetic resonance imaging system, generate (204) radiation therapy device control commands (172) using the magnetic resonance data and the treatment plan, irradiate (206) the target zone by controlling the radiation therapy device using the radiation therapy device control commands, measure (208) the radiation detection data during irradiation, and determine a time dependent radiation beam path (176) and a time dependent radiation beam intensity (178) using the radiation detection data.
摘要翻译：本发明提供一种包括磁共振成像系统（104）的医疗设备（100,300,400,800），包括台架（106）和辐射源（110）的辐射治疗设备（102）和辐射源检测系统（102），其可操作用于测量辐射检测数据（174），所述辐射检测数据描述辐射束与所述对象周围的至少一个表面（144,144'，144“）的相交处的辐射束的路径和强度，至少一个辐射检测器（144,144'，144“）。机器可读指令的执行使得控制医疗设备的处理器：使用磁共振成像系统从处理计划（168）接收（200）磁共振数据（164），从成像区获取（202）磁共振数据（164），生成（204）使用磁共振数据和治疗方案的放射治疗装置控制命令（172）通过使用放射线治疗装置控制指令控制放射线治疗装置照射（206）目标区域，在照射期间测量（208）放射线检测数据，并且使用辐射检测数据确定时间相关的辐射束路径（176）和时间相关的辐射束强度（178）。

12. 发明申请

WO2013114233A1 AUTOMATIC CURRENT SWITCHING OF CURRENT LEADS FOR SUPERCONDUCTING MAGNETS 审中-公开
标题翻译：用于超导磁体的电流自动切换
公开(公告)号：WO2013114233A1
公开(公告)日：2013-08-08
申请号：PCT/IB2013/050333
申请日：2013-01-14
申请人： KONINKLIJKE PHILIPS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH
发明人： OVERWEG, Johannes Adrianus , AMTHOR, Thomas Erik , FORTHMANN, Peter , UHLEMANN, Falk , DAVID, Bernd
IPC分类号： H01F6/00 , H01F6/06
CPC分类号： G01R33/3642 , G01R33/34 , G01R33/3815 , H01F6/008 , H01F6/06 , H01F6/065 , H01H36/008
摘要： The invention provides for magnetic resonance imaging system (600) comprising a superconducting magnet (100) with a first current lead (108) and a second current lead (110) for connecting to a current ramping system (624). The magnet further comprises a vacuum vessel (104) penetrated by the first current lead and the second current lead. The magnet further comprises a magnet circuit (106) within the vacuum vessel. The magnet circuit has a first magnet circuit connection (132) and a second magnet circuit connection (134). The magnet further comprises a first switch (120) between the first magnet connection and the first current lead and a second switch (122) between the second magnet connection and the second current lead. The magnet further comprises a first current shunt (128) connected across the first switch and a second current shunt (130) connected across the second switch. The magnet further comprises a first rigid coil loop (124) operable to actuate the first switch. The first rigid coil loop forms a portion of the first electrical connection. The magnet further comprises a second rigid coil loop (126) operable to actuate the second switch. The second rigid coil loop forms a portion of the second electrical connection.
摘要翻译：本发明提供了包括具有第一电流引线（108）的超导磁体（100）和用于连接到电流斜坡系统（624）的第二电流引线（110）的磁共振成像系统（600）。磁体还包括由第一电流引线和第二电流引线穿透的真空容器（104）。磁体还包括在真空容器内的磁体回路（106）。磁体电路具有第一磁体电路连接（132）和第二磁体电路连接（134）。磁体还包括在第一磁体连接和第一电流引线之间的第一开关（120）和在第二磁体连接和第二电流引线之间的第二开关（122）。磁体还包括跨越第一开关连接的第一电流分流器（128）和连接在第二开关上的第二电流分流器（130）。磁体还包括可操作以致动第一开关的第一刚性线圈环（124）。第一刚性线圈环形成第一电连接的一部分。磁体还包括可操作以致动第二开关的第二刚性线圈环（126）。第二刚性线圈环形成第二电连接的一部分。

13. 发明申请

WO2018108643A1 MULTI-STATE MAGNETIC RESONANCE FINGERPRINTING 审中-公开
公开(公告)号：WO2018108643A1
公开(公告)日：2018-06-21
申请号：PCT/EP2017/081601
申请日：2017-12-06
申请人： KONINKLIJKE PHILIPS N.V.
发明人： SOMMER, Karsten , DONEVA, Mariya Ivanova , AMTHOR, Thomas Erik , KOKEN, Peter , MEINEKE, Jan Jakob
IPC分类号： G01R33/50 , G06F19/00
摘要： The invention provides for a magnetic resonance imaging system (100) for acquiring magnetic resonance data (142) from a subject (118) within a measurement zone (108). The magnetic resonance imaging system (100) comprises: a processor (130) for controlling the magnetic resonance imaging system (100) and a memory (136) storing machine executable instructions (150, 152, 154), pulse sequence commands (140) and a dictionary (144). The pulse sequence commands (140) are configured for controlling the magnetic resonance imaging system (100) to acquire the magnetic resonance data (142) of multiple steady state free precession (SSFP) states per repetition time. The pulse sequence commands (140) are further configured for controlling the magnetic resonance imaging system (100) to acquire the magnetic resonance data (142) of the multiple steady state free precession (SSFP) states according to a magnetic resonance fingerprinting protocol. The dictionary (144) comprises a plurality of tissue parameter sets. Each tissue parameter set is assigned with signal evolution data pre-calculated for multiple SSFP states.

14. 发明申请

WO2016124414A1 MR FINGERPRINTING FOR DETERMINING PERFORMANCE DEGRADATION OF THE MR SYSTEM 审中-公开
标题翻译：用于确定MR系统的性能降级的MR指纹
公开(公告)号：WO2016124414A1
公开(公告)日：2016-08-11
申请号：PCT/EP2016/051274
申请日：2016-01-22
申请人： KONINKLIJKE PHILIPS N.V.
发明人： BOERNERT, Peter , DONEVA, Mariya Ivanova , AMTHOR, Thomas Erik , KOKEN, Peter , KEUPP, Jochen
IPC分类号： G01R33/46 , G01R33/54 , G01R33/58 , G06F19/00 , G01R33/48
CPC分类号： G01R33/4625 , G01R33/4828 , G01R33/54 , G01R33/546 , G01R33/58 , G06F19/00 , G16H40/40
摘要： The invention provides for a method of operating a magnetic resonance system for acquiring magnetic resonance data (152) from a phantom (124) within a measurement (zone 108). The phantom comprises a known volume of at least one predetermined substance ((128), 130). The method comprises the step of acquiring (300) the magnetic resonance data by controlling the magnetic resonance system with pulse sequence instructions (150). The pulse sequence instructions cause the magnetic resonance system to acquire the magnetic resonance data according to a magnetic resonance fingerprinting technique. The pulse sequence instructions specifiy a train of pulse sequence repetitions. Each pulse sequence repetition has a repetition time chosen from a distribution of repetition times. Each pulse sequence repetition comprises a radio frequency pulse chosen from a distribution of radio frequency pulses. The distribution of radio frequency pulses cause magnetic spins to rotate to a distribution of flip angles. Each pulse sequence repetition comprises a sampling event where the magnetic resonance signal is sampled for a predetermined duration at a sampling time before the end of the pulse sequence repetition. The method further comprises determining (302) one or more performance degradation conditions of the magnetic resonance system by comparing the magnetic resonance data with a magnetic resonance fingerprinting dictionary (154). The magnetic resonance fingerprinting dictionary contains a listing of magnetic resonance signals for a set of system states in response to execution of the pulse sequence instructions for each of the at least one predetermined substance.
摘要翻译：本发明提供一种操作磁共振系统的方法，用于从测量（区域108）内的体模（124）获取磁共振数据（152）。该幻影包括已知体积的至少一种预定物质（（128），130）。该方法包括通过用脉冲序列指令（150）控制磁共振系统来获取（300）磁共振数据的步骤。脉冲序列指令使磁共振系统根据磁共振指纹技术获取磁共振数据。脉冲序列指令指定一系列脉冲序列重复。每个脉冲序列重复具有从重复次数的分布中选择的重复时间。每个脉冲序列重复包括从射频脉冲分布中选出的射频脉冲。射频脉冲的分布导致磁旋转到翻转角分布。每个脉冲序列重复包括采样事件，其中磁共振信号在脉冲序列重复结束之前的采样时间被采样预定的持续时间。该方法还包括通过将磁共振数据与磁共振指纹词典（154）进行比较来确定（302）磁共振系统的一个或多个性能降级条件。磁共振指纹词典包含响应于对于至少一种预定物质中的每一种的脉冲序列指令的执行而针对一组系统状态的磁共振信号的列表。

15. 发明申请

WO2016075020A1 MAGNETIC RESONANCE FINGERPRINTING USING A SPIN-ECHO PULSE SEQUENCE WITH AN ADDITIONAL 180 DEGREE RF PULSE 审中-公开
标题翻译：使用附加180度RF脉冲的旋转脉冲序列指向磁性共振
公开(公告)号：WO2016075020A1
公开(公告)日：2016-05-19
申请号：PCT/EP2015/075775
申请日：2015-11-05
申请人： KONINKLIJKE PHILIPS N.V.
发明人： AMTHOR, Thomas Erik , DONEVA, Mariya Ivanova , KOKEN, Peter , KEUPP, Jochen , BOERNERT, Peter
IPC分类号： G01R33/46 , G01R33/465 , G01R33/50 , G01R33/54 , G01R33/565 , A61B5/055
CPC分类号： G01R33/4828 , A61B5/055 , G01R33/4625 , G01R33/465 , G01R33/50 , G01R33/54 , G01R33/56563
摘要： The invention provides for a magnetic resonance system (100) for acquiring a magnetic resonance data from a subject (118) within a measurement zone (108) according to a magnetic resonance fingerprinting technique. The pulse sequence comprises a train of pulse sequence repetitions (302, 304). Each pulse sequence repetition has a repetition time chosen from a distribution of repetition times. Each pulse sequence repetition comprises a radio frequency pulse (306) chosen from a distribution of radio frequency pulses. The distribution of radio frequency pulses cause magnetic spins to rotate to a distribution of flip angles, and each pulse sequence repetition comprises a sampling event (310) at a sampling time chosen from a distribution of sampling times. Each pulse sequence repetition of the pulse sequence comprises a first 180 degree RF pulse (308) performed at a first temporal midpoint between the radio frequency pulse and the sampling event to refocus the magnetic resonance signal. Each pulse sequence repetition of the pulse sequence comprises a second 180 degree RF pulse (309) performed at a second temporal midpoint between the sampling event and the start of the next pulse repetition.
摘要翻译：本发明提供一种磁共振系统（100），用于根据磁共振指纹技术从测量区域（108）内的对象（118）获取磁共振数据。脉冲序列包括一系列脉冲序列重复（302,304）。每个脉冲序列重复具有从重复次数的分布中选择的重复时间。每个脉冲序列重复包括从射频脉冲的分布中选择的射频脉冲（306）。射频脉冲的分布导致磁旋转到翻转角分布，并且每个脉冲序列重复包括从采样时间分布中选出的采样时间的采样事件（310）。脉冲序列的每个脉冲序列重复包括在射频脉冲和采样事件之间的第一时间中点执行的第一180度RF脉冲（308），以重新聚焦磁共振信号。脉冲序列的每个脉冲序列重复包括在采样事件和下一个脉冲重复的开始之间的第二时间中点执行的第二180度RF脉冲（309）。

16. 发明申请

WO2016059498A1 SYSTEM FOR REAL-TIME ORGAN SEGMENTATION AND TOOL NAVIGATION DURING TOOL INSERTION IN INTERVENTIONAL THERAPY AND METHOD OF OPEPERATION THEREOF 审中-公开
标题翻译：传统治疗工具插入期间实时机构分类和工具导航系统及其开发方法
公开(公告)号：WO2016059498A1
公开(公告)日：2016-04-21
申请号：PCT/IB2015/057466
申请日：2015-09-30
申请人： KONINKLIJKE PHILIPS N.V. , SUNNYBROOK HEALTH SCIENCES CENTRE
发明人： BHARAT, Shyam , DEHGHAN MARVAST, Ehsan , KRUECKER, Jochen , RAVI, Ananth , UHLEMANN, Falk , KUNG, Cynthia Ming-fu , AMTHOR, Thomas Erik
IPC分类号： A61B19/00
CPC分类号： G06T7/0012 , A61B5/4381 , A61B34/20 , A61B90/37 , A61B2034/2051 , A61B2090/364 , A61B2090/378 , G06T7/10 , G06T2207/10132
摘要： An interventional therapy system (100, 200, 300, 900) may include at least one controller (102, 202, 910) which may obtain a reference image dataset (540) of an object of interest (OOI); segment the reference image dataset to determine peripheral outlines (545) of the OOI in the plurality image slices; acquire a current image of the OOI (548) using an ultrasound probe (114, 224); select a peripheral outline (CBS, 545) of a selected image slice of the plurality of slices of the reference image dataset which is determined to correspond to the current image; and/or modify the selected peripheral outline of the image slice of the plurality of slices of the reference image dataset in accordance with at least one deformation vector (549).
摘要翻译：介入治疗系统（100,200,300,900）可以包括至少一个控制器（102,202,910），其可以获得感兴趣对象（50I）的参考图像数据集（540）; 分割参考图像数据集以确定多个图像切片中的OOI的外围轮廓（545）; 使用超声探头（114,224）获取所述OOI（548）的当前图像; 选择被确定为对应于当前图像的参考图像数据集的多个切片的选定图像切片的外围轮廓（CBS，545）; 和/或根据至少一个变形向量（549）修改参考图像数据集的多个切片的所选择的外围轮廓。

17. 发明申请

WO2023274757A1 IMMERSIVE AUDIO IN MEDICAL IMAGING AND INTERVENTIONS 审中-公开
公开(公告)号：WO2023274757A1
公开(公告)日：2023-01-05
申请号：PCT/EP2022/066643
申请日：2022-06-20
申请人： KONINKLIJKE PHILIPS N.V.
发明人： LEUSSLER, Christoph , AMTHOR, Thomas Erik
IPC分类号： H04S7/00 , A61B5/055 , H04S2400/11 , H04S2420/01 , H04S7/303 , H04S7/304
摘要： The present invention relates to a method (100) for providing audio to a subject (200) undergoing a diagnostic imaging or medical procedure. The method comprises receiving (101) at least one audio stream and receiving (102) a definition of at least one source point in a three-dimensional space. The method comprises transforming (103) the at least one audio stream into at least two audio signals for corresponding sound outlets, in which these sound outlets are in a predetermined physical spatial configuration with respect to the subject during the procedure. The method also comprises outputting (105) the at least two audio signals to the corresponding sound outlets to produce sound audible by the subject. The step of transforming (103) comprises spatially encoding the audio stream into the at least two audio signals such that the produced sound corresponding to the audio stream appears, to the subject, to originate from the defined source point.

18. 发明申请

WO2022008329A1 MAGNETIC RESONANCE FINGERPRINTING QUALITY ASSURANCE 审中-公开
公开(公告)号：WO2022008329A1
公开(公告)日：2022-01-13
申请号：PCT/EP2021/068112
申请日：2021-07-01
申请人： KONINKLIJKE PHILIPS N.V.
发明人： AMTHOR, Thomas Erik , DONEVA, Mariya Ivanova , KOKEN, Peter , NEHRKE, Kay
IPC分类号： G01R33/56 , G01R33/561
摘要： Disclosed herein is a medical system (100, 300) comprising a memory (110) storing machine executable instructions (120) and an MRF scoring module (122). The MRF scoring module is configured for outputting an MRF quality score (126) in response to receiving MRF data (124) as input. The medical system further comprises a computational system (106) configured for controlling the medical system, wherein execution of the machine executable instructions causes the computational system to: receive (200) the MRF data; receive (202) the MRF quality score in response to inputting the MRF data into an MRF scoring module; append (206) the MRF quality score to the MRF data if the MRF quality score is within a predetermined range (128); and provide (208) a signal (132) if the MRF quality score is outside of the predetermined range.

19. 发明申请

WO2015169498A1 TREATMENT PLANNING SYSTEM 审中-公开
标题翻译：治疗计划系统
公开(公告)号：WO2015169498A1
公开(公告)日：2015-11-12
申请号：PCT/EP2015/056108
申请日：2015-03-23
申请人： KONINKLIJKE PHILIPS N.V. , SUNNYBROOK HEALTH SCIENCES CENTRE
发明人： AMTHOR, Thomas Erik , UHLEMANN, Falk , BHARAT, Shyam , DEHGHAN MARVAST, Ehsan , KUNG, Cynthia Ming-fu , RAVI, Ananth , KRUECKER, Jochen
IPC分类号： A61N5/10
CPC分类号： A61N5/103 , A61N5/1027 , A61N2005/1041
摘要： The generation of the pattern and for the adaptation to the specific geometry requires a lot of manual work. It is an object of the invention to simplify the workflow for the clinician during treatment planning. This object is achieved by a treatment planning system configured for determining a set of catheter or needle insertion positions to be used during treatment comprising. The treatment planning system comprises an image providing module for providing a medical image from which at least one treatment target structure can be derived. Further the treatment planning system comprises a pattern providing module for providing one or a set of standard patterns for catheter or needle insertion comprising a plurality of catheter or needle insertion positions, wherein the catheter or needle positions relate to treatment positions in the at least one treatment target structure.
摘要翻译：模式的生成和适应特定几何需要大量的人工工作。本发明的一个目的是简化治疗计划期间临床医生的工作流程。该目的通过一种治疗计划系统来实现，所述治疗计划系统被配置用于确定在治疗期间使用的一组导管或针插入位置，包括。治疗计划系统包括用于提供医学图像的图像提供模块，从该图像可以导出至少一个治疗目标结构。此外，治疗计划系统包括模式提供模块，用于提供包括多个导管或针插入位置的导管或针插入的一个或一组标准图案，其中导管或针位置涉及至少一个治疗中的治疗位置目标结构。

20. 发明申请

WO2022175453A1 DATA ACQUISITION FOR DRIVING REAL-TIME WORKFLOWS IN A HOSPITAL ENVIRONMENT 审中-公开
公开(公告)号：WO2022175453A1
公开(公告)日：2022-08-25
申请号：PCT/EP2022/054077
申请日：2022-02-18
申请人： KONINKLIJKE PHILIPS N.V.
发明人： UHLEMANN, Falk , AMTHOR, Thomas Erik , SCHMIDT, Joachim Dieter , FINDEKLEE, Christian , WANG, Xinyu , BORGERT, Jörn
IPC分类号： G16H40/20 , G06Q10/06 , G06Q10/10 , G16H40/67
摘要： In order to monitor real-time process and workflows, modular sensors may be deployed and a processing server may receive sensor information from the modular sensors. The processing server may contextualize the received sensor information and generate a real-time process and workflow status based on the contextualized sensor information.

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