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11. 发明授权

US6093529A Imaging materials 失效
标题翻译：成像材料
公开(公告)号：US6093529A
公开(公告)日：2000-07-25
申请号：US60881
申请日：1998-04-16
申请人： Hirohiko Tsuzuki , Hisashi Okamura , Itsuo Fujiwara , Yoshiharu Yabuki , Masaki Noro
发明人： Hirohiko Tsuzuki , Hisashi Okamura , Itsuo Fujiwara , Yoshiharu Yabuki , Masaki Noro
IPC分类号： G03C1/498 , G03C1/490 , G03C1/815
CPC分类号： G03C1/49845 , G03C1/49872 , G03C1/49863
摘要： An imaging material is provided in the form of a photothermographic or thermographic image forming layer containing an organic silver salt on one surface of a support and further comprising a polyvalent metal ion and a phthalic acid compound on the image forming layer-bearing surface of the support. The imaging material has improved shelf stability before and after image formation and the ease of handling and produces high-quality blue black tone images.
摘要翻译：成像材料以支持体的一个表面上含有有机银盐的光热照相或热成像图像形式的形式提供，并且在载体的图像形成层承载表面上还包含多价金属离子和邻苯二甲酸化合物。成像材料在图像形成之前和之后具有改善的储存稳定性和易于处理并产生高质量的蓝黑色调图像。

12. 发明授权

US5922529A Photothermographic material 失效
标题翻译：光热成像材料
公开(公告)号：US5922529A
公开(公告)日：1999-07-13
申请号：US996914
申请日：1997-12-23
申请人： Hirohiko Tsuzuki , Hisashi Okada , Yoshio Inagaki
发明人： Hirohiko Tsuzuki , Hisashi Okada , Yoshio Inagaki
IPC分类号： C09B23/00 , G03C1/498 , G03C1/08 , G03C1/34
CPC分类号： G03C1/49854 , G03C1/49845
摘要： A photothermographic material has a photosensitive layer containing a binder, organic silver salt, reducing agent, and silver halide on one surface of a support. The photosensitive layer further contains a specific sulfur-containing compound and a merocyanine dye of specific structure and has an absorbance of 0.15-1.0 at an exposure wavelength. Sharpness, sensitivity, and aging stability are improved.
摘要翻译：光热敏成像材料在载体的一个表面上具有含有粘合剂，有机银盐，还原剂和卤化银的感光层。感光层还含有特定的含硫化合物和特定结构的部花青染料，并且在曝光波长下的吸光度为0.15-1.0。清晰度，灵敏度和老化稳定性得到提高。

13. 发明授权

US07723122B2 Method for analyzing test substance by surface plasmon resonance analysis 有权
标题翻译：通过表面等离子体共振分析分析测试物质的方法
公开(公告)号：US07723122B2
公开(公告)日：2010-05-25
申请号：US11213716
申请日：2005-08-30
申请人： Hirohiko Tsuzuki
发明人： Hirohiko Tsuzuki
IPC分类号： G01N24/00 , G01N21/62 , G01N33/53
CPC分类号： G01N21/553 , G01N21/276 , Y10S436/805 , Y10T436/24
摘要： It is an object of the present invention to provide a method for analyzing the interaction of a test substance with a ligand by analyzing a phenomenon whereby multiple test substances are simultaneously adsorbed to a ligand. The present invention provides a method for analyzing the interaction of test substances with a ligand by measuring the change in the surface plasmon resonance using a surface plasmon resonance measurement device wherein the above-described method comprises: supplying a solution containing two or more types of test substances after supplying a solution containing no test substances; measuring the change in the surface plasmon resonance; and analyzing the difference between the change in the surface plasmon resonance that is predicted from the adsorption rate constant (ka) and dissociation rate constant (kd) of each of the test substances that had previously been measured and the change in the surface plasmon resonance that has actually been measured.
摘要翻译：本发明的目的是提供一种通过分析同时将多种测试物质吸附到配体上的现象来分析测试物质与配体的相互作用的方法。本发明提供了一种通过使用表面等离子体共振测量装置测量表面等离子体共振的变化来分析测试物质与配体的相互作用的方法，其中上述方法包括：提供含有两种或多种类型的测试的溶液提供不含检测物质的溶液后的物质; 测量表面等离子体共振的变化; 并分析从先前测量的每种测试物质的吸附速率常数（ka）和解离速率常数（kd）预测的表面等离子体共振的变化与表面等离子体共振的变化之间的差异，实际上已被测量。

14. 发明授权

US07417737B2 Method for measuring surface plasmon resonance 有权
标题翻译：表面等离子体共振测量方法
公开(公告)号：US07417737B2
公开(公告)日：2008-08-26
申请号：US11000401
申请日：2004-12-01
申请人： Koji Kuruma , Hirohiko Tsuzuki
发明人： Koji Kuruma , Hirohiko Tsuzuki
IPC分类号： G01N21/55
CPC分类号： G01N21/553 , G01N33/54373
摘要： An object of the present invention is to suppress the noise width of a reference cell during measurement and the base line fluctuation. The present invention provides a method for measuring a change in surface plasmon resonance, which comprises: using a surface plasmon resonance measurement device comprising a flow channel system having a cell formed on a metal film and a light-detecting means for detecting the state of surface plasmon resonance by measuring the intensity of a light beam totally reflected on the meal film; and exchanging the liquid contained in the above flow channel system, wherein the above method is characterized in that a change in surface plasmon resonance is measured in a state where the flow of the liquid has been stopped, after the liquid contained in the above flow channel system has been exchanged.
摘要翻译：本发明的目的是抑制测量期间参考单元的噪声宽度和基线波动。本发明提供了一种用于测量表面等离子体共振的变化的方法，其包括：使用表面等离子体共振测量装置，其包括具有形成在金属膜上的单元的流路系统和用于检测表面状态的光检测装置通过测量在餐膜上完全反射的光束的强度来进行等离子体共振; 并且更换包含在上述流道系统中的液体，其中上述方法的特征在于，在液体包含在上述流动通道中的液体已经停止的状态下，测量表面等离子体共振的变化系统已经交换。

15. 外观设计

USD530235S1 Sensor chip for biochemical analyzer 有权
公开(公告)号：USD530235S1
公开(公告)日：2006-10-17
申请号：US29237425
申请日：2005-09-01
申请人： Hitoshi Shimizu , Katsuaki Muraishi , Tatsuo Fujikura , Hirohiko Tsuzuki , Kouji Kuruma , Masayasu Konishi , Yoshiyuki Kunuki
设计人： Hitoshi Shimizu , Katsuaki Muraishi , Tatsuo Fujikura , Hirohiko Tsuzuki , Kouji Kuruma , Masayasu Konishi , Yoshiyuki Kunuki

16. 外观设计

USD529829S1 Sensor chip for biochemical analyzer 有权
公开(公告)号：USD529829S1
公开(公告)日：2006-10-10
申请号：US29237422
申请日：2005-09-01
申请人： Hitoshi Shimizu , Katsuaki Muraishi , Tatsuo Fujikura , Hirohiko Tsuzuki , Kouji Kuruma , Masayasu Konishi , Yoshiyuki Kunuki
设计人： Hitoshi Shimizu , Katsuaki Muraishi , Tatsuo Fujikura , Hirohiko Tsuzuki , Kouji Kuruma , Masayasu Konishi , Yoshiyuki Kunuki

17. 发明授权

US07022523B2 Carrier for cell culture 有权
标题翻译：细胞培养载体
公开(公告)号：US07022523B2
公开(公告)日：2006-04-04
申请号：US10691506
申请日：2003-10-24
申请人： Hirohiko Tsuzuki , Satoru Toda , Makoto Kato
发明人： Hirohiko Tsuzuki , Satoru Toda , Makoto Kato
IPC分类号： C12N5/00
CPC分类号： C12N5/00 , C12N5/0068 , C12N2533/54 , C12N2533/72 , C12N2533/74
摘要： A carrier for cell culture comprising a water-containing polymer gel containing chitosan, wherein the water-containing polymer gel is coated with collagen and/or alginic acid, and a carrier for cell culture, which comprises a gel layer containing chitosan and an inorganic layer adjacently provided to the gel layer.
摘要翻译： 1.一种细胞培养用载体，其特征在于，含有含有壳聚糖的含水聚合物凝胶，其中，所述含水聚合物凝胶用胶原和/或藻酸包被，以及用于细胞培养的载体，其含有含有壳聚糖和无机层的凝胶层相邻地提供到凝胶层。

18. 发明申请

US20050216205A1 Method for measuring surface plasmon resonance 有权
标题翻译：表面等离子体共振测量方法
公开(公告)号：US20050216205A1
公开(公告)日：2005-09-29
申请号：US11085071
申请日：2005-03-22
申请人： Hirohiko Tsuzuki
发明人： Hirohiko Tsuzuki
IPC分类号： G01N33/48 , G01N33/50 , G01N33/543 , G06F19/00
CPC分类号： G01N33/54373 , Y10T436/117497
摘要： An object of the present invention is to suppress variations in measurement values when measuring a specific binding reaction between a physiologically active substance and a tested substance using a surface plasmon resonance measurement device, so that binding detection data with high reliability is obtained. The present invention provides a method for measuring a change in surface plasmon resonance, which comprises: using a surface plasmon resonance measurement device comprising a flow channel system having a cell formed on a metal film and a light-detecting means for detecting the state of surface plasmon resonance by measuring the intensity of a light beam totally reflected on the metal film; and exchanging the liquid contained in the above flow channel system, wherein a major axis of the metal film is 0.1 μm or more and 100 μm or less; a molecule interacting with an analyzed molecule is immobilized on the surface of the metal film; the distance between metal films is 200 μm or more and 10 mm or less; and the molecule interacting with the analyzed molecule is not immobilized on any parts other than the metal films.
摘要翻译：本发明的目的在于，使用表面等离子体共振测定装置测定生理活性物质和检测物质之间的特异性结合反应时，可以抑制测定值的变化，从而获得高可靠性的结合检测数据。本发明提供了一种用于测量表面等离子体共振的变化的方法，其包括：使用表面等离子体共振测量装置，其包括具有形成在金属膜上的单元的流路系统和用于检测表面状态的光检测装置通过测量在金属膜上全反射的光束的强度来进行等离子体共振; 并且更换包含在上述流路系统中的液体，其中金属膜的长轴为0.1μm以上且100μm以下; 与分析的分子相互作用的分子固定在金属膜的表面上; 金属膜之间的距离为200μm以上且10mm以下; 并且与分析的分子相互作用的分子不固定在除金属膜之外的任何部分上。

19. 发明授权

US06761691B2 Image forming method used in ultrasonic diagnosis, ultrasonic diagnostic apparatus, signal processing apparatus, and recording medium for recording signal processing program 有权
标题翻译：用于超声波诊断的图像形成方法，超声波诊断装置，信号处理装置以及用于记录信号处理程序的记录介质
公开(公告)号：US06761691B2
公开(公告)日：2004-07-13
申请号：US09907577
申请日：2001-07-19
申请人： Hirohiko Tsuzuki
发明人： Hirohiko Tsuzuki
IPC分类号： A61B814
CPC分类号： A61B8/4281 , A61B8/14 , G01S7/52025 , G01S7/52038 , G01S7/52046
摘要： An ultrasonic diagnostic apparatus by which an image having superior space resolution is obtained. The apparatus includes: first means for transmitting an ultrasonic wave, which is continued for at least two cycles, to an object to be inspected, and for detecting an echo signal which is produced by reflection of the transmitted ultrasonic wave from tissue of the object to be inspected to thereby obtain a detection signal; second means for delaying the detection signal by such a time duration corresponding to one cycle of the transmitted ultrasonic wave to thereby obtain a delayed detection signal; and third means for obtaining image information related to the tissue of the object to be inspected based upon a difference between the detection signal and the delayed detection signal.
摘要翻译：一种获得具有优异的空间分辨率的图像的超声波诊断装置。该装置包括：第一装置，用于将持续至少两个周期的超声波发送到待检查对象，并且用于检测通过从物体的组织反射发射的超声波产生的回波信号，检查检测信号; 第二装置，用于将检测信号延迟与所发射的超声波的一个周期对应的持续时间，从而获得延迟的检测信号; 以及第三装置，用于根据检测信号和延迟的检测信号之间的差异获得与被检查对象的组织有关的图像信息。

20. 发明授权

US5965346A Photothermographic material 失效
标题翻译：光热成像材料
公开(公告)号：US5965346A
公开(公告)日：1999-10-12
申请号：US904252
申请日：1997-07-31
申请人： Yoshio Inagaki , Naoyuki Hanaki , Hirohiko Tsuzuki
发明人： Yoshio Inagaki , Naoyuki Hanaki , Hirohiko Tsuzuki
IPC分类号： G03C1/12 , G03C1/498
CPC分类号： G03C1/49854 , G03C1/12 , G03C1/49818
摘要： A photothermographic material is disclosed, comprising a support having on at least one surface thereof a light-sensitive silver halide grain, an organic salt, a reducing agent for silver ion and a binder, wherein the heat-developable light-sensitive material contains a methine dye represented by formula (I).
摘要翻译：公开了一种光热照相材料，其包括在至少一个表面上具有感光卤化银颗粒，有机盐，银离子还原剂和粘合剂的载体，其中可热显影光敏材料含有次甲基由式（I）表示的染料。

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