会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 15. 发明授权
    • Antiinflammatory analgesic gelled ointment
    • 抗炎镇痛凝胶软膏
    • US4525347A
    • 1985-06-25
    • US468491
    • 1983-02-22
    • Toshio InagiToyojiro MuramatsuHidetaka Nagai
    • Toshio InagiToyojiro MuramatsuHidetaka Nagai
    • A61K31/405A61K47/18A61K47/32A61K47/38A61K31/40A61K31/78
    • A61K31/405A61K47/18A61K47/32A61K47/38A61K9/0014
    • An antiinflammatory analgesic ointment comprising: (a) an antiinflammatory amount of indomethacin; (b) a medium consisting of a hydroxy compound in the range of from 15 to 85% by weight, water in the range of 30 to 55% by weight and a gelating agent being present in an amount sufficient to effect gelation of said ointment and selected from the group consisting of a cellulose compound and a carboxyvinyl polymer which has been neutralized with aqueous ammonia or an amine; (c) an adjuvant being present in the range of from 0.5 to 5% by weight and selected from the group consisting of a C.sub.1 -C.sub.5 alcohol ester of a C.sub.4 -C.sub.14 monocarboxylic acid and a C.sub.1 -C.sub.3 alcohol diester of a C.sub.4 -C.sub.10 dicarboxylic acid; and (d) water in an amount sufficient to make up the balance of the ointment, said ointment being adjusted in its pH from an acidic to slightly basic level sufficient to solubilize said indomethacin in the composition but not too basic a pH level to cause decomposition of said indomethacin.
    • 一种抗炎止痛软膏,其包含:(a)抗炎剂量的吲哚美辛; (b)由15至85重量%的羟基化合物,30至55重量%的水和80至55重量%的水,和足以使所述软膏发生凝胶化的量的凝胶剂, 选自纤维素化合物和已经用氨水或胺中和的羧基乙烯基聚合物; (c)佐剂以0.5-5重量%的范围存在,并且选自C 4 -C 14单羧酸的C 1 -C 5醇酯和C 4 -C 10的C 1 -C 3醇二酯 二羧酸 和(d)足以构成软膏平衡的量的水,所述软膏的pH值从酸性至碱性水平调节至足以将所述吲哚美辛溶解于组合物中,但不过多碱性的pH值导致分解 的所述吲哚美辛。