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    • 17. 发明授权
    • Process for producing blocked isocyanate compound
    • 封端异氰酸酯化合物的制备方法
    • US07504518B2
    • 2009-03-17
    • US11666696
    • 2005-10-27
    • Hideo MiyataMasatoshi MurakamiKatsutoshi Ohno
    • Hideo MiyataMasatoshi MurakamiKatsutoshi Ohno
    • C07D231/00C07D231/10
    • C07D231/32C07D231/12
    • Disclosed is a process for producing a blocked isocyanate compound represented by general formula (III): wherein R1, R2, Q1, and Q2 are as defined in the specification, characterized by comprising reacting a pyrazole compound (I) with an ethylenically unsaturated group-containing isocyanate compound (II) at a temperature in the range of 0° C. to 90° C. The production process can efficiently produce a high-purity blocked isocyanate compound without substantially producing by-products. In the production process, unlike the prior art technique, since there is no need to use any inert solvent such as toluene or xylene, safety to the human body and environment is excellent and the production processes and equipment can be simplified. The blocked isocyanate compound produced by the production process contains no residual inert solvent and is suitable for use in extensive fields such as various coating agents, adhesives, and molding materials.
    • 公开了一种制备由通式(III)表示的封端异氰酸酯化合物的方法:其中R1,R2,Q1和Q2如说明书中所定义,其特征在于包括使吡唑化合物(I)与烯属不饱和基团 - 含有异氰酸酯化合物(II)的温度在0℃〜90℃的范围内。制造方法可以有效地制造高纯度的封端异氰酸酯化合物而基本不产生副产物。 在生产过程中,与现有技术不同,由于不需要使用甲苯或二甲苯等惰性溶剂,因此对人体和环境的安全性优异,可以简化生产方法和设备。 通过生产方法生产的封端异氰酸酯化合物不含残留的惰性溶剂,适用于各种涂料,粘合剂和成型材料等广泛领域。