专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明授权

US08703763B2 Bridged piperidine derivatives 有权
标题翻译：桥连哌啶衍生物
公开(公告)号：US08703763B2
公开(公告)日：2014-04-22
申请号：US13405404
申请日：2012-02-27
申请人： Karlheinz Baumann , Luke Green , Anja Limberg , Thomas Luebbers , Andrew Thomas
发明人： Karlheinz Baumann , Luke Green , Anja Limberg , Thomas Luebbers , Andrew Thomas
IPC分类号： A01N43/00 , A61K31/55 , C07D413/00 , C07D415/00 , C07D417/00 , C07D419/00
CPC分类号： C07D451/04
摘要： The present invention relates to compounds of formula I hetaryl I, hetaryl II, R1, R2, R3, Y, m, and o or to pharmaceutically active acid addition salts thereof. The present compounds of formula I are modulators for amyloid beta and thus, they may be useful for the treatment or prevention of a disease associated with the deposition of β-amyloid in the brain, in particular Alzheimer's disease, and other diseases such as cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica and Down syndrome.
摘要翻译：本发明涉及式I化合物，杂芳基I，杂芳基II，R 1，R 2，R 3，Y，m和o的化合物或其药物活性酸加成盐。本发明式I化合物是淀粉样蛋白β的调节剂，因此它们可用于治疗或预防与脑中淀粉样蛋白沉积相关的疾病，特别是阿尔茨海默氏病和其他疾病如脑淀粉样血管病，淀粉样变性遗传性脑出血，荷兰型（HCHWA-D），多发性梗死性痴呆，痴呆和唐氏综合征。

12. 发明申请

US20120225884A1 BRIDGED PIPERIDINE DERIVATIVES 有权
标题翻译：桥连哌啶衍生物
公开(公告)号：US20120225884A1
公开(公告)日：2012-09-06
申请号：US13405404
申请日：2012-02-27
申请人： Karlheinz Baumann , Luke Green , Anja Limberg , Thomas Luebbers , Andrew Thomas
发明人： Karlheinz Baumann , Luke Green , Anja Limberg , Thomas Luebbers , Andrew Thomas
IPC分类号： A61K31/4985 , C07D451/04 , C07D487/04 , A61P25/00 , A61K31/437 , A61K31/506 , A61K31/519 , A61P25/28 , C07D471/04 , A61K31/444
CPC分类号： C07D451/04
摘要： The present invention relates to compounds of formula I hetaryl I, hetaryl II, R1, R2, R3, Y, m, and o or to pharmaceutically active acid addition salts thereof. The present compounds of formula I are modulators for amyloid beta and thus, they may be useful for the treatment or prevention of a disease associated with the deposition of β-amyloid in the brain, in particular Alzheimer's disease, and other diseases such as cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica and Down syndrome.
摘要翻译：本发明涉及式I化合物，杂芳基I，杂芳基II，R 1，R 2，R 3，Y，m和o的化合物或其药物活性酸加成盐。本发明式I化合物是淀粉样蛋白β的调节剂，因此它们可用于治疗或预防与脑中淀粉样蛋白沉积相关的疾病，特别是阿尔茨海默氏病和其他疾病如脑淀粉样血管病，淀粉样变性遗传性脑出血，荷兰型（HCHWA-D），多发性梗死性痴呆，痴呆和唐氏综合征。

13. 发明授权

US06536494B1 Pneumatic vehicle tire 有权
标题翻译：气动车轮胎
公开(公告)号：US06536494B1
公开(公告)日：2003-03-25
申请号：US09469319
申请日：1999-12-22
申请人： Karlheinz Baumann , Robert Nau , Günter Dietrich
发明人： Karlheinz Baumann , Robert Nau , Günter Dietrich
IPC分类号： B60C1700
CPC分类号： B60C15/0072 , B60C1/0025 , B60C3/04 , B60C9/18 , B60C15/0018 , B60C15/0036 , B60C15/06 , B60C17/0009
摘要： Pneumatic vehicle tires comprising a carcass which extends between two bead rings, a belt arrangement provided between the carcass and a tread strip, and also rubber reinforcing plies arranged in the sidewall regions, which adopt a supporting function when the tire is deflated, are characterized in that a single rubber reinforcing ply is arranged radially within a first carcass ply and its maximum thickness is disposed in the upper half of the sidewall height; with the rubber reinforcing ply extending from the bead apex region up to and beneath the edge region of the belt ply, and with the bead apex, which extends approximately up to the half sidewall height, being surrounded by the first carcass ply.
摘要翻译：其特征在于，包括在两个胎圈环之间延伸的胎体，设置在胎体和胎面带之间的带布置以及布置在侧壁区域中的橡胶加强层的气动车辆轮胎，其在轮胎放气时采取支撑功能。单个橡胶增强帘布层径向设置在第一胎体帘布层内，并且其最大厚度设置在侧壁高度的上半部分中; 其中橡胶增强层从胎圈三角形区域延伸到带束层的边缘区域的下方和下方，并且具有大致高达半侧壁高度的胎圈三角形被第一胎体帘布层包围。

14. 发明申请

US20050227995A1 Phenyl sulfoxides and phenyl sulfones 审中-公开
标题翻译：苯基亚砜和苯基砜
公开(公告)号：US20050227995A1
公开(公告)日：2005-10-13
申请号：US10501105
申请日：2003-01-07
申请人： Martin Hendrix , Karlheinz Baumann , Rolf Grosser , Gerhard Konig , Vera Dusterhus , Joachim Kruger
发明人： Martin Hendrix , Karlheinz Baumann , Rolf Grosser , Gerhard Konig , Vera Dusterhus , Joachim Kruger
IPC分类号： C07D295/20 , A61K31/10 , A61K31/235 , A61K31/27 , A61K31/277 , A61K31/381 , A61K31/40 , A61K31/4015 , A61K31/438 , A61K31/445 , A61K31/4453 , A61K31/495 , A61K31/496 , A61K31/506 , A61K31/5375 , A61P25/28 , C07B53/00 , C07C315/02 , C07C315/04 , C07C317/18 , C07C317/44 , C07D207/06 , C07D207/40 , C07D207/46 , C07D211/16 , C07D211/22 , C07D211/46 , C07D211/48 , C07D211/52 , C07D211/60 , C07D213/74 , C07D239/42 , C07D241/08 , C07D295/205 , C07D333/20 , C07D491/10 , C07D491/113 , A61K31/401 , A61K31/4747
CPC分类号： C07D239/42 , C07C317/18 , C07C2601/14 , C07D207/06 , C07D207/46 , C07D211/22 , C07D211/46 , C07D211/52 , C07D213/74 , C07D241/08 , C07D295/205 , C07D491/10
摘要： The invention relates to phenyl sulfoxides and sulfones and processes for their preparation, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially Alzheimer's disease.
摘要翻译：本发明涉及苯基亚砜和砜及其制备方法，以及它们用于制备用于治疗和/或预防疾病，特别是阿尔茨海默氏病的药物的用途。

15. 发明授权

US06659994B1 Bag for storing a first substance injectable, in particular, in a human or animal body 失效
标题翻译：用于储存可注射的第一种物质的袋子，特别是在人体或动物体内
公开(公告)号：US06659994B1
公开(公告)日：2003-12-09
申请号：US09452300
申请日：1999-12-01
申请人： Helmut Mader , Michael Krause , Horst Schwietz , Franz Fritzmeier , Karlheinz Baumann
发明人： Helmut Mader , Michael Krause , Horst Schwietz , Franz Fritzmeier , Karlheinz Baumann
IPC分类号： A61B1900
CPC分类号： A61J1/2089 , A61J1/10 , A61J1/1475 , A61J1/201 , A61J1/2027 , A61J1/2093 , B65D81/32 , B67B7/24 , Y10S604/903
摘要： A bag arrangement for intermixing two, separately stored substances. The bag arrangement includes a bag having a jacket defining an inner chamber for accommodating a first substance and a piercing device having a chamber in which the jacket is received. A single piercing member is provided on one side of the jacket and a hollow abutment is located opposite the piercing member on an opposite side of the jacket and forms a receptacle for accommodating a second substance. Upon actuation of the piercing device, the piercing member pierces the opposite sides of the jacket providing for intermixing of the first and second substances.
摘要翻译：一种用于混合两种分开储存的物质的袋装置。袋装置包括具有限定用于容纳第一物质的内室的护套的袋和具有容纳夹套的室的穿孔装置。在护套的一侧上设置单个穿刺构件，并且在护套的相对侧上的穿孔构件相对的中空邻接部分形成用于容纳第二物质的容器。在穿刺装置致动时，刺穿构件刺穿护套的相对侧，用于混合第一和第二物质。

16. 发明授权

US6082585A Double bag for application of a fluid substance 失效
标题翻译：用于流体物质的双袋
公开(公告)号：US6082585A
公开(公告)日：2000-07-04
申请号：US196400
申请日：1998-11-19
申请人： Helmut Mader , Michael Krause , Horst Schwietz , Franz Fritzmeier , Karlheinz Baumann
发明人： Helmut Mader , Michael Krause , Horst Schwietz , Franz Fritzmeier , Karlheinz Baumann
IPC分类号： A61J1/05 , A61J1/00 , A61J1/10 , B65D75/38 , B65D35/22
CPC分类号： A61J1/10 , B65D75/38 , A61J1/1475
摘要： A double bag for application of a fluid substance including an outer bag having at least two adjoining each other edges, and an inner bag for receiving the fluid substance, located in the outer bag and having a length and a width which are shorter than inner dimensions of the outer bag, with the two adjoining each other edges of the outer bag and the inner bag defining together a free flooding region along the edges.
摘要翻译：一种用于施加流体物质的双层袋，其包括具有至少两个彼此相邻的边缘的外袋，以及用于容纳流体物质的内袋，其位于外袋中并具有比内部尺寸短的长度和宽度外袋的两个邻接的边缘和内袋沿边缘限定自由溢流区域。

17. 发明授权

US06986373B2 Automobile pneumatic tires including rubber reinforcing plies which take on a supporting function with a deflated tire 失效
标题翻译：汽车充气轮胎包括具有放气轮胎支撑功能的橡胶加强帘布层
公开(公告)号：US06986373B2
公开(公告)日：2006-01-17
申请号：US10752403
申请日：2004-01-06
申请人： Manfred Gerresheim , Karlheinz Baumann , Günter Dietrich
发明人： Manfred Gerresheim , Karlheinz Baumann , Günter Dietrich
IPC分类号： B60C17/00 , B60C15/00 , B60C15/06 , B60C1/00
CPC分类号： B60C17/00 , B60C15/0018 , B60C15/0072 , B60C15/06 , Y10T152/10846
摘要： An automobile pneumatic tire comprises a multiple-ply carcass extending in-between two bead rings having allocated bead fillers, a belt arrangement between the plies of the carcass and a tread strip, and rubber reinforcement plies in the sidewall sections assuming a supporting function where the tire is deflated. A first rubber reinforcement ply is inside a first ply of the carcass, a second rubber reinforcement ply is between the first ply of the carcass and the second ply of the carcass, and a third rubber reinforcement ply is between the second ply of the carcass and a third ply of the carcass. The three rubber reinforcement plies extend down with their ends staggered in relation to each other from the bead core area to the edge area of the belt ply. The three rubber plies have different heights in radial direction and different thickness over the height of the sidewall.
摘要翻译：汽车充气轮胎包括在两个胎圈环之间延伸的多层胎体，所述两个胎圈环具有分配的胎圈填料，在胎体的帘布层和胎面带之间的带布置，以及在侧壁部分中的橡胶加强层，其具有支撑功能，轮胎放气。第一橡胶增强层在胎体的第一层内，第二橡胶增强层位于胎体的第一层和胎体的第二层之间，第三橡胶增强层在胎体的第二层和胴体的第三层。三个橡胶加强层向下延伸，其端部彼此相交，从珠芯区域到带束层的边缘区域交错。三个橡胶层在径向方向上具有不同的高度，在侧壁的高度上具有不同的厚度。

18. 发明授权

US06688357B1 Automobile pneumatic tires including rubber reinforcing plies which take on a supporting function with a deflated tire 失效
标题翻译：汽车充气轮胎包括具有放气轮胎支撑功能的橡胶加强帘布层
公开(公告)号：US06688357B1
公开(公告)日：2004-02-10
申请号：US09806706
申请日：2001-08-07
申请人： Manfred Gerresheim , Karlheinz Baumann , Günter Dietrich
发明人： Manfred Gerresheim , Karlheinz Baumann , Günter Dietrich
IPC分类号： B60C100
CPC分类号： B60C17/00 , B60C15/0018 , B60C15/0072 , B60C15/06 , Y10T152/10846
摘要： An automobile pneumatic tire comprises a multiple ply carcass extending in-between two bead rings having allocated bead fillers, a belt arrangement between the plies of the carcass and a tread strip, and rubber reinforcement plies in the sidewall sections assuming a supporting function where the tire is deflated. A first rubber reinforcement ply is inside a first ply of the carcass, a second rubber reinforcement ply is between the first ply of the carcass and the second ply of the carcass and a third rubber reinforcement ply is between the second ply of the carcass and a third ply of the carcass. The three rubber reinforcement plies extend down with their ends staggered in relation to each other from the bead core area to the edge area of the belt ply. The three rubber plies have different heights in radial direction and different thickness over the height of the sidewall.
摘要翻译：汽车充气轮胎包括在两个胎圈环之间延伸的多层帘布层胎体，所述两个胎圈环具有分配的胎圈填料，在胎体的帘布层和胎面带之间的带布置，以及侧壁部分中的橡胶加强层，其中轮胎被放气第一橡胶增强帘布层在胎体的第一层内，第二橡胶增强层在胎体的第一层和胎体的第二层之间，第三橡胶增强层在胎体的第二层之间，胴体第三层。三个橡胶加强层向下延伸，其端部彼此相交，从珠芯区域到带束层的边缘区域交错。三个橡胶层在径向方向上具有不同的高度，在侧壁的高度上具有不同的厚度。

19. 发明授权

US06510883B2 Pneumatic vehicle tire including rubber reinforcing plies in side wall regions 有权
标题翻译：气动车辆轮胎，包括侧壁区域的橡胶加强层
公开(公告)号：US06510883B2
公开(公告)日：2003-01-28
申请号：US09834262
申请日：2001-04-12
申请人： Karlheinz Baumann , Günter Dietrich
发明人： Karlheinz Baumann , Günter Dietrich
IPC分类号： B60C300
CPC分类号： B60C17/0009 , B60C1/0025 , B60C15/06 , Y10T152/10819 , Y10T152/10837 , Y10T152/10846
摘要： The invention relates to pneumatic tires for a motor vehicle comprising a multi-layer carcass. Said multi-layer carcass extends between two bead rings, a set of bracing plies provided between the layers of the carcass and a tire tread, and rubber reinforcement layers arranged in the side wall areas which support the tire when it is deflated. The invention is characterized in that a first rubber reinforcement layer is arranged radially within a first carcass layer and a second rubber reinforcement layer is arranged between the first carcass layer and a second carcass layer. The two rubber reinforcement layers extend from the bead filler area to a position under the edge area of the bracing plies. The two rubber layers vary in thickness across the height of the side walls.
摘要翻译：本发明涉及一种用于机动车辆的充气轮胎，其包括多层胎体。所述多层胎体在两个胎圈环之间延伸，设置在胎体层和轮胎胎面之间的一组支撑帘布层，以及布置在侧壁区域中的橡胶加强层，其在放气时支撑轮胎。本发明的特征在于，第一橡胶加强层径向布置在第一胎体层内，第二橡胶加强层设置在第一胎体层和第二胎体层之间。两个橡胶加强层从胎圈填充区域延伸到支撑层的边缘区域下方的位置。两个橡胶层的厚度在侧壁的高度上变化。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式