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11. 发明专利

NZ510819A Polyketide synthase enzymes and recombinant DNA constructs therefor 未知
公开(公告)号：NZ510819A
公开(公告)日：2004-03-26
申请号：NZ51081999
申请日：1999-10-01
申请人： KOSAN BIOSCIENCES INC
发明人： KHOSLA CHAITAN , REEVES CHRISTOPHER , CHU DANIEL , ANTI DANIEL , WU KAI
IPC分类号： C12N15/09 , A61K31/436 , A61P25/00 , A61P37/06 , C07D498/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/10 , C12N9/12 , C12N15/52 , C12P17/18 , C12P19/32 , C12P19/62 , C12N15/54 , C12N15/62
摘要： Host cells comprising recombinant vectors encoding the FK-520 polyketide synthase and FK-520 modification enzymes can be used to produce the FK-520 polyketide. Recombinant DNA constructs comprising one or more FK-520 polyketide synthase domains, modules, open reading frames, and variants thereof can be used to produce recombinant polyketide synthases and a variety of different polyketides with application as pharmaceutical and veterinary products.

12. 发明专利

AT346938T 未知
公开(公告)号：AT346938T
公开(公告)日：2006-12-15
申请号：AT99970125
申请日：1999-10-01
申请人： KOSAN BIOSCIENCES INC
发明人： REEVES CHRISTOPHER , CHU DANIEL , KHOSLA CHAITAN , SANTI DANIEL , WU KAI
IPC分类号： C12N15/09 , A61K31/436 , A61P25/00 , A61P37/06 , C07D498/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/10 , C12N9/12 , C12N15/52 , C12P17/18 , C12P19/32 , C12P19/62 , C12N15/54 , C12N15/62 , C07D311/00
摘要： Polyketide compounds of the formula but not including FK-506, FK-520, 18-hydroxy-FK520 and 18-hydroxy-FK-506.

13. 发明专利

AU2001261432B2 Polyketide derivatives 未知
公开(公告)号：AU2001261432B2
公开(公告)日：2005-06-16
申请号：AU2001261432
申请日：2001-05-10
申请人： KOSAN BIOSCIENCES INC
发明人： SCHIRMER ANDREAS , SANTI DANIEL , REEVES CHRISTOPHER , KHOSLA CHAITAN , FARDIS MARIA , CHU DANIEL
IPC分类号： C12N15/09 , A61K31/436 , A61P17/00 , A61P17/06 , A61P25/00 , A61P37/06 , C07D498/18 , C12N1/21 , C12R1/465 , C07D471/04 , A61K031/4365 , A61K031/437 , A61P015/00 , C07D209/00 , C07D221/00 , C07D333/00 , C07D487/04 , C07D491/048 , C07D495/04

14. 发明专利

AU773517B2 Polyketide synthase enzymes and recombinant DNA constructs therefor 未知
公开(公告)号：AU773517B2
公开(公告)日：2004-05-27
申请号：AU1441500
申请日：1999-10-01
申请人： KOSAN BIOSCIENCES INC
发明人： REEVES CHRISTOPHER , CHU DANIEL , KHOSLA CHAITAN , SANTI DANIEL , WU KAI
IPC分类号： C12N15/09 , A61K31/436 , A61P25/00 , A61P37/06 , C07D498/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/10 , C12N9/12 , C12N15/52 , C12P17/18 , C12P19/32 , C12P19/62 , C12N15/54 , C12N15/62
摘要： Polyketide compounds of the formula but not including FK-506, FK-520, 18-hydroxy-FK520 and 18-hydroxy-FK-506.

15. 发明专利

AU1441500A Polyketide synthase enzymes and recombinant dna constructs therefor 未知
公开(公告)号：AU1441500A
公开(公告)日：2000-04-26
申请号：AU1441500
申请日：1999-10-01
申请人： KOSAN BIOSCIENCES INC
发明人： REEVES CHRISTOPHER , CHU DANIEL , KHOSLA CHAITAN , SANTI DANIEL , WU KAI
IPC分类号： C12N15/09 , A61K31/436 , A61P25/00 , A61P37/06 , C07D498/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/10 , C12N9/12 , C12N15/52 , C12P17/18 , C12P19/32 , C12P19/62 , C12N15/54 , C12N15/62
摘要： Polyketide compounds of the formula but not including FK-506, FK-520, 18-hydroxy-FK520 and 18-hydroxy-FK-506.

16. 发明专利

CA2343880A1 POLYKETIDE SYNTHASE ENZYMES AND RECOMBINANT DNA CONSTRUCTS THEREFOR 未知
公开(公告)号：CA2343880A1
公开(公告)日：2000-04-13
申请号：CA2343880
申请日：1999-10-01
申请人： KOSAN BIOSCIENCES INC
发明人： REEVES CHRISTOPHER , CHU DANIEL , WU KAI , SANTI DANIEL , KHOSLA CHAITAN
IPC分类号： C12N15/09 , A61K31/436 , A61P25/00 , A61P37/06 , C07D498/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/10 , C12N9/12 , C12N15/52 , C12P17/18 , C12P19/32 , C12P19/62 , C07D211/00 , C07D273/00 , C07D311/00 , C12N15/54 , C12N15/62
摘要： Host cells comprising recombinant vectors encoding the FK-520 polyketide synthase and FK-520 modification enzymes can be used to produce the FK-520 polyketide. Recombinant DNA constructs comprising one or more FK-520 polyketide synthase domains, modules, open reading frames, and variants thereof can be used to produce recombinant polyketide synthases and a variet y of different polyketides with application as pharmaceutical and veterinary products.

17. 发明专利

DE69934242T2 未知
公开(公告)号：DE69934242T2
公开(公告)日：2007-09-20
申请号：DE69934242
申请日：1999-10-01
申请人： KOSAN BIOSCIENCES INC
发明人： REEVES CHRISTOPHER , CHU DANIEL , KHOSLA CHAITAN , SANTI DANIEL , WU KAI
IPC分类号： C12N15/09 , C12N15/52 , A61K31/436 , A61P25/00 , A61P37/06 , C07D211/00 , C07D273/00 , C07D311/00 , C07D498/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/10 , C12N9/12 , C12N15/54 , C12N15/62 , C12P17/18 , C12P19/32 , C12P19/62
摘要： Polyketide compounds of the formula but not including FK-506, FK-520, 18-hydroxy-FK520 and 18-hydroxy-FK-506.

18. 发明专利

AU6143201A Novel polyketide derivatives 未知
公开(公告)号：AU6143201A
公开(公告)日：2001-11-26
申请号：AU6143201
申请日：2001-05-10
申请人： KOSAN BIOSCIENCES INC
发明人： CHU DANIEL , FARDIS MARIA , KHOSLA CHAITAN , REEVES CHRISTOPHER , SANTI DANIEL , SCHIRMER ANDREAS
IPC分类号： C12N15/09 , A61K31/436 , A61P17/00 , A61P17/06 , A61P25/00 , A61P37/06 , C07D498/18 , C12N1/21 , C12R1/465 , C07D471/04 , A61K31/4365 , A61K31/437 , A61P15/00 , C07D209/00 , C07D221/00 , C07D333/00 , C07D487/04 , C07D491/048 , C07D495/04

19. 发明专利

CA2370743A1 KETOLIDE ANTIBACTERIALS 未知
公开(公告)号：CA2370743A1
公开(公告)日：2000-10-26
申请号：CA2370743
申请日：2000-04-13
申请人： ORTHO MCNEIL PHARM INC , KOSAN BIOSCIENCES INC
发明人： GRANT EUGENE , HLASTA DENNIS , HENNINGER TODD , KHOSLA CHAITIN , CHU DANIEL
IPC分类号： A61K31/7048 , A61P31/04 , C07H17/08 , A61K31/70
摘要： A series of ketolide antibacterials in the macrolide family of formula (a), intermediates used in their manufacture and pharmaceutical compositions containing them. The compounds are erythromycin analogues useful in the treatment of bacterial and protozoal infections and in the treatment of othe r conditions involving gastric motility.

20. 发明专利

CA3109829A1 ULLR SNOWBOARD BINDINGS: SNOWBOARD BINDINGS WITH ROTATING AND POSITION LOCKING MECHANISM 未知
公开(公告)号：CA3109829A1
公开(公告)日：2022-08-22
申请号：CA3109829
申请日：2021-02-22
申请人： CHU DANIEL
发明人： CHU DANIEL
IPC分类号： A63C10/18
摘要： A snowboard binding equipment characterized by an assembly containing a 1-axis rotatable mechanism with a position locking lever. Intended to be attached between a snowboard and snowboard binding. This equipment allows the user to either rotate their feet freely in the Z-axis at any given time or lock their foot's position at a certain angle via the position locking lever, should they choose. Claims A snowboard binding adapter assembly comprising of a joint to allow free rotation in the Z-axis, and a mechanical assembly to allow the locking of the Z-axis position at a desired angle degree. Fig. 1. A spinning mechanism comprised of a joint to allow rotation in the Z-Axis Fig. 2. A locking mechanism comprised of a clamp lever, wire, locking teeth gear and two adjacent spinning gears Description Snowboard bindings typically only allow the user to lock their foot's position at one angle, typically around 15-degrees, meanwhile other types of snowboard styles such as alpine snowboarding have a more aggressive foot angle to allow for deeper carving, meanwhile during the snowboarder's chairlift ride, the feet position causes awkward and painful movements because the snowboarder has to hang the snowboard longitudinally while their foot is horizontal, all the meanwhile, snowboarders always desire to change or adjust their snowboard angles "on-the-fly" without having to unscrew and remove the bindings every time. Thus, it is practical to have a mechanism which allows free rotation and locking as well. This mechanism also allows snowboarders to transition from typical freestyle, park and alpine snowboarding styles without having to change equipment.

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