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11. 发明申请

WO2007102102A1 A DEVICE FOR MONITORING EXPOSURE TO RADIATION, USE OF SUCH A DEVICE, AN ARTICLE AND A METHOD FOR MONITORING EXPOSURE TO RADIATION 审中-公开
标题翻译：用于监测辐射暴露的装置，这种装置的使用，文章和用于监测辐射暴露的方法
公开(公告)号：WO2007102102A1
公开(公告)日：2007-09-13
申请号：PCT/IB2007/050638
申请日：2007-02-28
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , LUB, Johan , MEIJER, Eduard, J.
发明人： LUB, Johan , MEIJER, Eduard, J.
IPC分类号： G01J1/42 , G01J1/50
CPC分类号： G01J1/50 , G01J1/429 , G02F1/13718
摘要： A device (1) for monitoring exposure to radiation (L), particularly ultraviolet radiation, at least comprising cholesteric liquid crystal material (3) having a photo- isomerisable compound, such that during use, a light reflection band of the cholesteric liquid crystal material (3) can be modified upon exposure to the radiation to be monitored. The invention also provides a method for monitoring exposure to radiation.
摘要翻译：一种用于监测暴露于辐射（L）的装置（1），特别是紫外线辐射，至少包括具有光可异构化合物的胆甾型液晶材料（3），使得在使用期间胆甾型液晶材料的光反射带（3）可以在暴露于要监测的辐射之后进行修改。本发明还提供了一种监测辐射暴露的方法。

12. 发明申请

WO2004002935A1 CHIRAL DOPANT WITH PHENYLETHANEDIOL FUNCTIONALITY 审中-公开
标题翻译：具有苯乙醚功能的AL。
公开(公告)号：WO2004002935A1
公开(公告)日：2004-01-08
申请号：PCT/IB2003/002927
申请日：2003-06-13
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , LUB, Johan , WEGH, Rene, T.
发明人： LUB, Johan , WEGH, Rene, T.
IPC分类号： C07C69/90
CPC分类号： C07D493/04 , C07C69/92 , C09K19/586 , Y10T428/10 , Y10T428/1036
摘要： The invention pertains to a phenylethanediol derivative having at least one polymerizable group, characterized in that the phenylethanediol derivative further comprises at least one photo-convertible group for adjusting the helical twisting power of the phenylethanediol derivative. According to a preferred embodiment the phenylethanediol has the formulawherein A stands for a bond or a p-phenylene group; B and B' are independently (O)p-CoH2o-O-CO-CR'=CH2, o being 2-12, p being 0 or 1, and R' being H or CH3; P stands for a CH2 or a C=O group; Q and Q' are independently selected from H, C1-C3 alkyl, C1-C3 alkoxy, halogen, and CN;n is an integer from 1 to 3; andm is an integer from 0 to 2; and:wherein A stands for a bond or a p-phenylene group; B is (O)p-CoH2o-O-CO-CR'=CH2, o being 2-12, p is 1, and R' being H or CH3; P stands for a CH2 or a C=O group; Q is selected from H, C1-C3 alkyl, C1-C3 alkoxy, halogen, and CN; andm is an integer from 0 to 2.
摘要翻译：本发明涉及具有至少一个可聚合基团的苯乙二醇衍生物，其特征在于所述苯乙二醇衍生物还包含至少一个用于调节苯乙二醇衍生物的螺旋扭转能力的光转化基团。根据一个优选的实施方案，苯乙二醇具有甲醛，其中A代表键或对亚苯基; B和B'独立地为（O）p-CoH 2 O-O-CO-CR'= CH 2，o为2-12，p为0或1，R'为H或CH 3; P代表CH2或C = O基团; Q和Q'独立地选自H，C 1 -C 3烷基，C 1 -C 3烷氧基，卤素和CN; n是1至3的整数; andm是从0到2的整数; 和：其中A代表键或对亚苯基; B是（O）p-CoH 2 O-O-CO-CR'= CH 2，o是2-12，p是1，R'是H或CH 3; P代表CH2或C = O基团; Q选自H，C 1 -C 3烷基，C 1 -C 3烷氧基，卤素和CN; andm是0到2的整数。

13. 发明申请

WO2012042438A1 LIGHT-EMITTING ARRANGEMENT WITH ORGANIC PHOSPHOR 审中-公开
标题翻译：有机磷光发光装置
公开(公告)号：WO2012042438A1
公开(公告)日：2012-04-05
申请号：PCT/IB2011/054134
申请日：2011-09-21
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , LUB, Johan , HIKMET, Rifat, Ata Mustafa , WEGH, René, Theodorus
发明人： LUB, Johan , HIKMET, Rifat, Ata Mustafa , WEGH, René, Theodorus
IPC分类号： C09K11/06 , C08G63/13 , C08G63/199 , H01L51/50 , C08G63/181 , C08L67/02 , H05B33/14 , C08G63/183 , H01L51/52 , H01L51/00 , C08G63/187 , C08G63/127 , C08G63/189
CPC分类号： F21V9/30 , C08G63/181 , C08G63/187 , C08G63/199 , C09K11/06 , C09K2211/1011 , C09K2211/1044 , F21K9/64 , F21Y2101/00 , F21Y2115/10 , H05B33/14 , H05B33/20
摘要： The invention provides a light-emitting arrangement (100) comprising a light source (105) adapted to emit light of a first wavelength, and a wavelength converting member (106) arranged to receive light of said first wavelength and adapted to convert at least part of the light of said first wavelength to light of a second wavelength, said wavelength converting member comprising i) a carrier polymeric material comprising a polyester backbone comprising an aromatic moiety, and ii) at least one wavelength converting material of a specified general formula. The perylene derived compounds have been found to have excellent stability when incorporated into said matrix material.
摘要翻译：本发明提供了一种包括适于发射第一波长的光的光源（105）的发光装置（100）和布置成接收所述第一波长的光的波长转换构件（106），并且适于将至少部分所述波长转换元件包括i）载体聚合物材料，其包含包含芳族部分的聚酯主链，和ii）至少一种具有特定通式的波长转换材料。已经发现苝衍生化合物在掺入所述基体材料中时具有优异的稳定性。

14. 发明申请

WO2010029500A1 CHELATING AMPHIPHILIC POLYMERS 审中-公开
标题翻译：吸引人气聚合物
公开(公告)号：WO2010029500A1
公开(公告)日：2010-03-18
申请号：PCT/IB2009/053921
申请日：2009-09-08
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , GRUELL, Holger , DE VRIES, Anke , LANGEREIS, Sander , LUB, Johan , AUSSEMS-CUSTERS, Erica, M., G.
发明人： GRUELL, Holger , DE VRIES, Anke , LANGEREIS, Sander , LUB, Johan , AUSSEMS-CUSTERS, Erica, M., G.
IPC分类号： A61K9/51 , A61K47/48 , A61K49/00
CPC分类号： C08G81/025 , A61K9/107 , A61K9/1075 , A61K9/1273 , A61K9/5146 , A61K49/0414 , A61K49/126 , A61K49/1806 , A61K49/1812 , A61K49/1818 , A61K51/06 , A61K51/065 , A61K51/1217 , A61K51/1237 , A61K51/1251
摘要： Described are amphiphilic polymers that are provided with chelating moieties. The amphiphilic polymers are block copolymers comprising a hydrophilic block and a hydrophobic block, with the chelating moieties linked to the end-group of the hydrophilic block. The disclosed polymers are capable of self-assembly into structures such as micelles and polymersomes. With suitable metals present in the form of coordination complexes with 5 the chelating moieties, the chelating amphiphilic polymers of the invention are suitable for use in various imaging techniques requiring metal labeling, such as MRI (T 1 /T 2 weighted contrast agents or CEST contrast agents) SPECT, PET or Spectral CT.
摘要翻译：描述的是具有螯合部分的两亲性聚合物。两亲聚合物是包含亲水嵌段和疏水嵌段的嵌段共聚物，螯合部分连接到亲水嵌段的端基。所公开的聚合物能够自组装成结构如胶束和聚合物囊泡。使用与5个螯合部分配位络合物形式的合适金属，本发明的螯合两亲性聚合物适用于需要金属标记的各种成像技术，例如MRI（T 1 / T 2加权造影剂或CEST对比度药剂）SPECT，PET或光谱CT。

15. 发明申请

WO2004044631A1 CHOLESTERIC COLOR FILTER AND METHOD OF MANUFACTURING SUCH 审中-公开
标题翻译：彩色滤光片及其制造方法
公开(公告)号：WO2004044631A1
公开(公告)日：2004-05-27
申请号：PCT/IB2003/004624
申请日：2003-10-20
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , WEGH, Rene, T. , BROER, Dirk, J. , LUB, Johan
发明人： WEGH, Rene, T. , BROER, Dirk, J. , LUB, Johan
IPC分类号： G02B5/30
CPC分类号： G02B5/3025 , G02B5/3016
摘要： The invention pertains to a method of manufacturing a layer of a cholesterically ordered polymer material, in which the material is oriented in such a way that the axis of the molecular helix of the cholesterically ordered material extends transversely to the layer, wherein the method comprises the following steps: a) providing a layer comprising a cholesterically ordered material, which material comprises a quantity of a convertible compound, the conversion of said compound being inducible by radiation; b) irradiating the layer to convert at least a part of the convertible compound in the irradiated parts of the layer; c) optionally at least partially polymerizing and/or cross-linking the cholesterically ordered material to form a three-dimensional polymer; d) applying a diffusion agent onto the layer to transversely swell the layer as a function of the concentration variation of the diffusion agent; e) fixing the diffusion agent to the polymer to freeze in the formed structure.
摘要翻译：本发明涉及一种制造胆甾醇有序聚合物材料层的方法，其中材料以这样一种方式取向，使得胆甾醇排序材料的分子螺旋轴线横向于该层延伸，其中该方法包括以下步骤：a）提供包含胆甾醇排序材料的层，该材料包含一定数量的可转化化合物，所述化合物的转化可通过辐射诱导; b）照射该层以转换该层的照射部分中的可转换化合物的至少一部分; c）任选地至少部分聚合和/或交联胆甾醇排序的材料以形成三维聚合物; d）根据扩散剂的浓度变化，在该层上施加扩散剂以使该层横向膨胀; e）将扩散剂固定到聚合物上以在形成的结构中冷冻。

16. 发明申请

WO2012007886A1 LIPID BILAYER CARRIER FOR DRUGS OR IMAGING AGENTS 审中-公开
标题翻译：用于药物或成像剂的LIPID BILAYER载体
公开(公告)号：WO2012007886A1
公开(公告)日：2012-01-19
申请号：PCT/IB2011/053047
申请日：2011-07-08
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , LANGEREIS, Sander , GRUELL, Holger , DE SMET, Mariska , AUSSEMS-CUSTERS, Erica, Maria, Gerarda , LUB, Johan
发明人： LANGEREIS, Sander , GRUELL, Holger , DE SMET, Mariska , AUSSEMS-CUSTERS, Erica, Maria, Gerarda , LUB, Johan
IPC分类号： A61K9/127 , A61K31/704 , A61K41/00 , A61K49/18
CPC分类号： A61K9/127 , A61K31/704 , A61K41/0028 , A61K49/106 , A61K49/1812
摘要： Disclosed are carriers for drugs and/or MR imaging agents having a lipid bilayer shell comprising a phospholipid having two terminal alkyl chains, one being a short chain having a chain length of at most seven carbon atoms, the other being a long chain having a chain length of at least fifteen carbon atoms. The mixed long/short chain phospholipids serve to tune the release properties of the carrier. Preferred phospholipids are phosphatidylcholines.
摘要翻译：公开了具有脂质双层壳的药物和/或MR成像剂的载体，其包含具有两个末端烷基链的磷脂，一个是具有至多7个碳原子的链长的短链，另一个是具有链的长链长度至少十五个碳原子。混合的长/短链磷脂用于调节载体的释放性质。优选的磷脂是磷脂酰胆碱。

17. 发明申请

WO2011058488A1 A CHIP HOLDER KIT FOR A WIRE-GIRD SENSOR. 审中-公开
标题翻译：用于线束传感器的芯片支架套件。
公开(公告)号：WO2011058488A1
公开(公告)日：2011-05-19
申请号：PCT/IB2010/055032
申请日：2010-11-05
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , DE BOER, Ruth, W. I. , KLUNDER, Derk, J. W. , VAN HERPEN, Maarten, M. J. W. , PENTERMAN, Roel , LUB, Johan , DE WITZ, Christianne, R. M.
发明人： DE BOER, Ruth, W. I. , KLUNDER, Derk, J. W. , VAN HERPEN, Maarten, M. J. W. , PENTERMAN, Roel , LUB, Johan , DE WITZ, Christianne, R. M.
IPC分类号： G01N21/64 , B01L9/00 , G02B21/34
CPC分类号： G01N21/648 , B01L9/52 , B01L2300/0654 , B01L2300/0819 , B01L2300/0822 , G01N33/54373 , G01N2021/0367 , G01N2201/0245 , G02B21/26 , G02B21/34
摘要： This invention relates to a chip holder kit for a wire-grid sensor, where the chip holder kit includes a base plate, where a first aperture is formed at the front side of the base plate, a second aperture is formed at the rear side of the base plate, and an overlapping region where the first and the second apertures overlap. The second aperture has an area that substantially matches the area of the wire-grid sensor and is adapted to removable receive the wire-grid sensor. The first aperture is adapted to removably receive the polarization structure and the first and second apertures are arranged such that when the wire-grid sensor and the polarizer are received in the overlapping region the polarizer filters any incoming excitation light to a transverse electric mode (TE) polarized excitation light before the wire-grid sensor is illuminated.
摘要翻译：本发明涉及一种用于线栅传感器的芯片保持器套件，其中芯片保持器套件包括基板，其中在基板的前侧形成有第一孔，第二孔形成在底板的后侧基板和第一和第二孔重叠的重叠区域。第二孔具有与线栅传感器的面积基本匹配的区域，并适于可移除地接收线栅传感器。第一孔径适于可移除地接收偏振结构，并且第一和第二孔布置成使得当线栅传感器和偏振器被接收在重叠区域中时，偏振器将任何进入的激发光束滤波成横向电模式（TE ）线栅传感器点亮之前的偏振激发光。

18. 发明申请

WO2010119389A2 PRETARGETING KIT, METHOD AND AGENTS USED THEREIN 审中-公开
标题翻译：预备套件，使用的方法和代理
公开(公告)号：WO2010119389A2
公开(公告)日：2010-10-21
申请号：PCT/IB2010/051565
申请日：2010-04-12
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , ROBILLARD, Marc, S. , ROSSIN, Raffaella , LUB, Johan , RENART VERKERK, Pascal , BURDINSKI, Dirk
发明人： ROBILLARD, Marc, S. , ROSSIN, Raffaella , LUB, Johan , RENART VERKERK, Pascal , BURDINSKI, Dirk
IPC分类号： A61K47/48 , A61K51/04
CPC分类号： A61K51/0495 , A61K47/6897 , B82Y5/00
摘要： Described is a pretargeting method, and related kits, for targeted medical imaging and/or therapeutics, wherein use is made of abiotic reactive chemical groups that exhibit bio-orthogonal reactivity towards each other. The invention involves the use of [4+2] inverse electron demand (retro) Diels- Alder chemistry in providing the coupling between a Pre-targeting Probe and an Effector Probe. To this end one of these probes comprises an electron-deficient tetrazine or other suitable diene, and the other a cyclooctene or cyclooctyne.
摘要翻译：描述了用于靶向医学成像和/或治疗剂的预靶向方法和相关试剂盒，其中使用对彼此显示出生物正交反应性的非生物反应性化学基团。本发明涉及使用[4 + 2]反电子需求（复古）Diels-Alder化学来提供预瞄准探针和效应探针之间的耦合。为此，这些探针中的一个包括电子缺乏四嗪或其它合适的二烯，另一个是环辛烯或环辛烯。

19. 发明申请

WO2010119382A1 PRETARGETING KIT, METHOD AND AGENTS USED THEREIN 审中-公开
标题翻译：预备套件，使用的方法和代理
公开(公告)号：WO2010119382A1
公开(公告)日：2010-10-21
申请号：PCT/IB2010/051547
申请日：2010-04-12
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , ROBILLARD, Marc, S. , ROSSIN, Raffaella , LUB, Johan , RENART VERKERK, Pascal , BURDINSKI, Dirk
发明人： ROBILLARD, Marc, S. , ROSSIN, Raffaella , LUB, Johan , RENART VERKERK, Pascal , BURDINSKI, Dirk
IPC分类号： A61K47/48 , A61K51/04 , A61K51/10
CPC分类号： B82Y5/00 , A61K47/6897 , A61K51/0495 , A61K51/1027 , A61K51/1045
摘要： Described is a pretargeting method, and related kits, for targeted medical imaging and/or therapeutics, wherein use is made of abiotic reactive chemical groups that exhibit bio-orthogonal reactivity towards each other. The invention involves the use of [4+2] inverse electron demand (retro) Diels-Alder chemistry in providing the coupling between a Pre-targeting Probe and an Effector Probe. To this end one of these probes comprises an electron-deficient tetrazine or other suitable diene, and the other an alkene or alkyne dienohile.
摘要翻译：描述了用于靶向医学成像和/或治疗剂的预靶向方法和相关试剂盒，其中使用对彼此显示出生物正交反应性的非生物反应性化学基团。本发明涉及使用[4 + 2]反电子需求（复古）Diels-Alder化学来提供预瞄准探针和效应探针之间的耦合。为此目的，这些探针之一包含电子缺乏四嗪或其它合适的二烯，另一种是烯烃或炔烃二酮。

20. 发明申请

WO2005034099A2 INFORMATION MEDIUM COMPRISING TWO LAYERS, METHOD OF MANUFACTURING SUCH AN INFORMATION MEDIUM, DEVICE FOR READING SUCH AN INFORMATION MEDIUM 审中-公开
标题翻译：包含两层的信息介质，制造这种信息介质的方法，用于读取这些信息介质的设备
公开(公告)号：WO2005034099A2
公开(公告)日：2005-04-14
申请号：PCT/IB2004/003033
申请日：2004-09-17
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , LUB, Johan , BROER, Dirk, Jan , KURT, Ralph , HENDRIKS, Robert, Frans, Maria
发明人： LUB, Johan , BROER, Dirk, Jan , KURT, Ralph , HENDRIKS, Robert, Frans, Maria
IPC分类号： G11B7/00
CPC分类号： G11B7/24038 , G11B7/245 , G11B7/25 , G11B7/266
摘要： The present invention relates to an information medium comprising a first information layer (L1) and a second information layer (L2), said first and second information layers (L1, L2) comprising marks intended to store binary data, each mark being intended to be read by a light spot polarized according to a first direction (d1) or to a second direction (d2), wherein: the first information layer (L1) comprises first marks (101) sensitive to the first polarization direction, and second marks (102) not sensitive to said first polarization direction, said first and second marks being both not sensitive or equally sensitive to the second polarization direction, the second information layer (L2) comprising third marks (103) sensitive to the second polarization direction, and fourth marks (104) not sensitive to said second polarization direction, said third and fourth marks being both not sensitive or equally sensitive to the first polarization direction.
摘要翻译：本发明涉及包括第一信息层（L1）和第二信息层（L2）的信息介质，所述第一和第二信息层（L1，L2）包括用于存储二进制数据的标记，每个标记旨在是通过根据第一方向（d1）或第二方向（d2）偏振的光点读取，其中：第一信息层（L1）包括对第一偏振方向敏感的第一标记（101）和第二标记（102 ）对所述第一偏振方向不敏感，所述第一和第二标记对第二偏振方向都不敏感或不敏感，第二信息层（L2）包括对第二偏振方向敏感的第三标记（103）和第四标记（104）对所述第二偏振方向不敏感，所述第三和第四标记对第一偏振方向都不敏感或同等敏感。

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