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11. 发明申请

US20090220993A1 Method and Compositions for Specifically Detecting Physiologically Acceptable Polymer Molecules 有权
标题翻译：用于特异性检测生理上可接受的聚合物分子的方法和组合物
公开(公告)号：US20090220993A1
公开(公告)日：2009-09-03
申请号：US12342405
申请日：2008-12-23
申请人： Peter Turecek , Juergen Siekmann , Alfred Weber , Herbert Gritsch , Katalin Varadi , Susanne Vejda
发明人： Peter Turecek , Juergen Siekmann , Alfred Weber , Herbert Gritsch , Katalin Varadi , Susanne Vejda
IPC分类号： G01N33/566
CPC分类号： G01N33/86 , G01N33/5308 , G01N2430/60
摘要： The present invention relates to a method for determining the amount of a physiologically acceptable polymer molecule bound to a protein, an antibody or other composition being capable of specifically binding to a physiologically acceptable polymer molecule, and a kit containing said antibody or composition.
摘要翻译：本发明涉及一种用于测定与蛋白质结合的生理学上可接受的聚合物分子的量的方法，能够特异性结合生理上可接受的聚合物分子的抗体或其它组合物，以及含有所述抗体或组合物的试剂盒。

12. 发明申请

US20080234193A1 Von Willebrand factor-and factor VIII-polymer conjugates having a releasable linkage 有权
标题翻译： Von Willebrand因子和具有可释放键的因子VIII-聚合物缀合物
公开(公告)号：US20080234193A1
公开(公告)日：2008-09-25
申请号：US12006059
申请日：2007-12-27
申请人： Mary J. Bossard , Gayle Stephenson , Zhihao Fang , Harold Zappe , Stacy Mitchell , Ping Zhang , Friedrich Scheiflinger , Peter Turecek , Juergen Siekmann , Katalin Varadi , Herbert Gritsch
发明人： Mary J. Bossard , Gayle Stephenson , Zhihao Fang , Harold Zappe , Stacy Mitchell , Ping Zhang , Friedrich Scheiflinger , Peter Turecek , Juergen Siekmann , Katalin Varadi , Herbert Gritsch
IPC分类号： A61K47/48 , C07K14/00 , A61K38/16
CPC分类号： C07K14/755 , A61K47/60
摘要： The present invention provides von Willebrand Factor-polymer conjugates and Factor VIII-polymer conjugates, each having a releasable linkage. Methods of making conjugates, methods for administering conjugates, are also provided.
摘要翻译：本发明提供了von Willebrand因子 - 聚合物共轭物和因子VIII-聚合物缀合物，其各自具有可释放的连接。还提供了制备缀合物的方法，用于施用缀合物的方法。

13. 发明申请

US20130012442A1 VON WILLEBRAND FACTOR- AND FACTOR VIII-POLYMER CONJUGATES HAVING A RELEASABLE LINKAGE 有权
标题翻译：具有可释放链接的VON WILLEBRAND因子和因子VIII聚合物
公开(公告)号：US20130012442A1
公开(公告)日：2013-01-10
申请号：US13620285
申请日：2012-09-14
申请人： Mary J. Bossard , Gayle Stephenson , Zhihao Fang , Harold Zappe , Stacy Mitchell , Ping Zhang , Friedrich Scheiflinger , Peter Turecek , Juergen Siekmann , Katalin Varadi , Herbert Gritsch
发明人： Mary J. Bossard , Gayle Stephenson , Zhihao Fang , Harold Zappe , Stacy Mitchell , Ping Zhang , Friedrich Scheiflinger , Peter Turecek , Juergen Siekmann , Katalin Varadi , Herbert Gritsch
IPC分类号： C07K14/755 , A61P7/00 , A61K38/37
CPC分类号： C07K14/755 , A61K47/60
摘要： The present invention provides von Willebrand Factor-polymer conjugates and Factor VIII-polymer conjugates, each having a releasable linkage. Methods of making conjugates, methods for administering conjugates, are also provided.
摘要翻译：本发明提供了von Willebrand因子 - 聚合物共轭物和因子VIII-聚合物缀合物，其各自具有可释放的连接。还提供了制备缀合物的方法，用于施用缀合物的方法。

14. 发明授权

US08133865B2 von Willebrand factor- and factor VIII-polymer conjugates having a releasable linkage 有权
标题翻译： von Willebrand因子和因子VIII-聚合物缀合物具有可释放的连接
公开(公告)号：US08133865B2
公开(公告)日：2012-03-13
申请号：US12006059
申请日：2007-12-27
申请人： Mary J. Bossard , Gayle Stephenson , Zhihao Fang , Harold Zappe , Stacy Mitchell , Ping Zhang , Friedrich Scheiflinger , Peter Turecek , Juergen Siekmann , Katalin Varadi , Herbert Gritsch
发明人： Mary J. Bossard , Gayle Stephenson , Zhihao Fang , Harold Zappe , Stacy Mitchell , Ping Zhang , Friedrich Scheiflinger , Peter Turecek , Juergen Siekmann , Katalin Varadi , Herbert Gritsch
IPC分类号： A61K38/36 , C07K14/755
CPC分类号： C07K14/755 , A61K47/60
摘要： The present invention provides von Willebrand Factor-polymer conjugates and Factor VIII-polymer conjugates, each having a releasable linkage. Methods of making conjugates, methods for administering conjugates, are also provided.
摘要翻译：本发明提供了von Willebrand因子 - 聚合物共轭物和因子VIII-聚合物缀合物，其各自具有可释放的连接。还提供了制备缀合物的方法，用于施用缀合物的方法。

15. 发明授权

US4561076A Sonar method and apparatus 失效
标题翻译：声纳法和仪器
公开(公告)号：US4561076A
公开(公告)日：1985-12-24
申请号：US498778
申请日：1983-05-27
申请人： Herbert Gritsch
发明人： Herbert Gritsch
IPC分类号： G01S15/87 , G01S15/89
CPC分类号： G01S15/87 , G01S15/003
摘要： A method and apparatus for underwater ranging with the aid of sonic pulses, by irradiating a given transmitting area with sonic energy pulses from a transmitter mounted in a marine vessel, receiving sonic energy echoes reflected from bodies in the transmitting area in a manner which is selective with respect to direction in a plurality of receiving sectors arranged in a fan shape, and associating the received echoes with respective reflection centers within the respective receiving sectors on the basis of associated sonic pulse travel times. Reception is carried out on a second marine vessel different from the vessel carrying the transmitter and which travels at a rearward offset position from the vessel carrying the transmitter at such a distance therefrom that the receiving sectors cover at least part of the given transmitting area, and the azimuthal width of the transmitting area is made very small. The associating operation includes determining the relative distance between the two vessels and the direction of the transmitting area, relative to the heading of the second vessel, at least at the moment of transmission of each sonic pulse, in order to associate the reflection centers with the echoes.
摘要翻译：一种通过借助于声波脉冲进行水下测距的方法和装置，通过用安装在海洋船舶中的发射器的声能脉冲辐射给定的发射区域，以选择性的方式接收从发射区域中的物体反射的声能回波相对于以风扇形状布置的多个接收扇区中的方向，并且基于相关联的声波脉冲行进时间将接收到的回波与各个接收扇区内的各个反射中心相关联。接收在不同于承载变送器的船只的第二船只船上进行，并且在距离运送发射机的船只在向后偏移位置处行进，距离接收扇区覆盖给定传送区域的至少一部分，以及传输区域的方位角宽度非常小。关联操作包括至少在每个声波脉冲的传输时间确定两个容器之间的相对距离和相对于第二容器的航向的发射区域的方向，以便将反射中心与回声。

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