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    • 11. 发明授权
    • Process for the production of 2-pyrrolidone
    • 2-吡咯烷酮生产方法
    • US4151171A
    • 1979-04-24
    • US914107
    • 1978-06-09
    • Victor P. Kurkov
    • Victor P. Kurkov
    • C07D207/26C07D207/263C07D207/00
    • C07D207/27
    • A process for producing N-acyl-2-pyrrolidone which comprises a contacting N-acyl allylamine with carbon monoxide in the presence of an aliphatic carboxylic acid solvent and a homogeneous catalyst of palladium or platinum coordinated with triphenylphosphine. According to a preferred embodiment, the acyl group is removed from the N-acyl-2-pyrrolidone by contacting and heating the N-acyl-2-pyrrolidone with allylamine to thereby effect transacylation and obtain product 2-pyrrolidone and N-acyl-allylamine as a recycle feed stream. Alternatively, N-acyl-2-pyrrolidone can be hydrolyzed to 2-pyrrolidone and the carboxylic acid derived from the acyl group.
    • N-酰基-2-吡咯烷酮的制备方法,其包括在脂族羧酸溶剂和与三苯基膦配位的钯或铂的均相催化剂存在下,使N-酰基烯丙胺与一氧化碳接触。 根据优选的实施方案,通过N-酰基-2-吡咯烷酮与烯丙胺的接触和加热将酰基从N-酰基-2-吡咯烷酮中除去,从而进行转酰胺化,得到2-吡咯烷酮和N-酰基 - 烯丙胺 作为再循环进料流。 或者,N-酰基-2-吡咯烷酮可以水解成2-吡咯烷酮和衍生自酰基的羧酸。