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    • 15. 发明授权
    • Amino-bicyclic pyrazinones and pyridinones as coagulation serine protease inhibitors
    • 氨基双环吡嗪酮和吡啶酮作为凝血丝氨酸蛋白酶抑制剂
    • US07037911B2
    • 2006-05-02
    • US10465538
    • 2003-06-19
    • Xiaojun Zhang
    • Xiaojun Zhang
    • C07D487/04A61K31/407A61P7/02
    • C07D487/04
    • The present invention relates generally to compounds that inhibit serine proteases. In particular it is directed to novel amino-bicyclic pyrazinone and pyridinone compounds of Formula (I): or a stereoisomer or pharmaceutically acceptable salt form thereof, which are useful as selective inhibitors of serine protease enzymes of the coagulation cascade; for example thrombin, factor Xa, factor XIa, factor IXa, and/or factor VIIa. In particular, it relates to compounds that are factor VIIa inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of using the same.
    • 本发明一般涉及抑制丝氨酸蛋白酶的化合物。 特别地,其涉及式(I)的新型氨基 - 双环吡嗪酮和吡啶酮化合物或其立体异构体或药学上可接受的盐形式,其可用作凝血级联的丝氨酸蛋白酶的选择性抑制剂; 例如凝血酶,因子Xa,因子XIa,因子IXa和/或因子VIIa。 特别地,它涉及作为因子VIIa抑制剂的化合物。 本发明还涉及包含这些化合物的药物组合物及其使用方法。
    • 16. 发明授权
    • Method for automatically positioning the blade of a motor grader to a memory position
    • 将自动平地机的叶片自动定位到记忆位置的方法
    • US06278955B1
    • 2001-08-21
    • US09208357
    • 1998-12-10
    • Matthew A. HartmanMark D. ShaneDaniel E. ShearerXiaojun Zhang
    • Matthew A. HartmanMark D. ShaneDaniel E. ShearerXiaojun Zhang
    • G06F1900
    • E02F3/847
    • A system and method for automatically adjusting the blade of a motor grader to an operator programmed blade position. The method includes the steps of: providing an electronic controller and blade controls having position sensors; monitoring the output of the position sensors to ascertain the position of the blade controls; receiving a first input signal for setting a memory blade position; determining the memory blade position based on the output of the position sensors; receiving a second input signal for requesting the memory blade position; determining the present blade position based on the output of the position sensors; and producing a control signal for actuating the blade controls to move the blade from the present blade position to the memory blade position.
    • 一种用于将自动平地机的叶片自动调节到操作者编程刀片位置的系统和方法。 该方法包括以下步骤:提供具有位置传感器的电子控制器和叶片控制; 监测位置传感器的输出以确定叶片控制器的位置; 接收用于设定存储刀片位置的第一输入信号; 基于所述位置传感器的输出来确定所述存储器刀片位置; 接收用于请求所述存储器刀片位置的第二输入信号; 基于所述位置传感器的输出来确定所述刀片位置; 并且产生用于致动叶片控制器以将叶片从当前叶片位置移动到存储刀片位置的控制信号。
    • 18. 发明申请
    • Indexing Bottle Cap for Use with a Container
    • 用于容器的分度瓶盖
    • US20130292354A1
    • 2013-11-07
    • US13887943
    • 2013-05-06
    • Tao XuXiaojun ZhangLinzhi Fang
    • Tao XuXiaojun ZhangLinzhi Fang
    • A61J7/04
    • A61J7/04A61J1/03A61J7/0436B65D51/24
    • An indexing cap assembly indexes visual cues or indicia during an open and close cycle so as to help users more easily track container entry as for example with regard to medications so as to ensure proper dosage. The indexing cap assembly basically incorporates six components, including a cover construction, an indexing plate or wheel, a compression coil or spring, a push plate construction, a gear tray or swing plate construction, and an assembly ring. The cover construction and assembly ring are joined together to essentially form or close the cap assembly with the other parts coaxially aligned and operable therebetween. The indexing wheel is rotatively received within the cover construction such that axial displacements of the push plate advance the indexing wheel and indicia upon its upper surface are sequentially revealed by way of the window formed in the cover construction.
    • 索引盖组件在开放和关闭循环期间指示视觉提示或标记,以帮助用户更容易地跟踪容器进入,例如关于药物,以确保适当的剂量。 分度盖组件基本上包括六个部件,包括盖结构,分度板或轮,压缩线圈或弹簧,推板结构,齿轮盘或回转板结构以及组装环。 盖构造和组装环连接在一起以基本上形成或闭合盖组件,其它部件同轴对准并在其间可操作。 分度轮被旋转地容纳在盖结构内,使得推板的轴向位移使分度轮前进,并且其上表面上的标记通过形成在盖结构中的窗口顺序地显露。
    • 19. 发明授权
    • Book spread identification arrangement for a board book
    • 书籍书籍传播识别安排
    • US08200146B2
    • 2012-06-12
    • US11990908
    • 2006-08-23
    • Craig Allen WhiteSatyajit DebTao XuXiaojun ZhangRong Zhang
    • Craig Allen WhiteSatyajit DebTao XuXiaojun ZhangRong Zhang
    • G09B5/00
    • G09B5/00G09B5/062
    • A book spread identification arrangement for a board book is provided, the arrangement comprising a plurality of conductive paths, contact means disposed adjacent at least part of at least one of the conductive paths and processing means connected to the conductive paths and configured for processing signals associated with the conductive paths. One selection end of each path is disposed adjacent the spine surface of the book. The contact means comprise one or more conductive surfaces and are arranged, upon opening of the book to a spread, to contact one of a plurality of combinations of one or more of the conductive paths. Each of the plurality of combinations is in a predetermined unique association with a respective single spread of the book. From the processed signals, the processing means are able to determine the particular combination of conductive paths contacted by the contact means and identify to which spread the book is open.
    • 提供了一种用于电路板书籍的书扩展识别装置,该装置包括多个导电路径,邻近至少一个导电路径的至少一部分设置的接触装置和连接到导电路径的处理装置,并被配置用于处理相关信号 与导电路径。 每个路径的一个选择端设置在书的脊柱表面附近。 接触装置包括一个或多个导电表面,并且在将书打开到扩展部上时布置成接触一个或多个导电路径的多个组合之一。 多个组合中的每一个与书的相应的单次展开处于预定的唯一关联。 从处理过的信号中,处理装置能够确定由接触装置接触的导电路径的特定组合,并且识别该书打开哪个展开。