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11. 发明授权

US09021670B2 Device for collapsing and loading a heart valve into a minimally invasive delivery system 有权
公开(公告)号：US09021670B2
公开(公告)日：2015-05-05
申请号：US13211484
申请日：2011-08-17
申请人： Theodore Paul Dale , Aaron J. Chalekian , Valerie J. Glazier , Huisun Wang
发明人： Theodore Paul Dale , Aaron J. Chalekian , Valerie J. Glazier , Huisun Wang
IPC分类号： A61F2/24 , A61F2/95
CPC分类号： A61F2/2427 , A61F2/2418 , A61F2002/9522 , Y10T29/49927 , Y10T29/53657 , Y10T29/53796 , Y10T29/53843 , Y10T29/53852 , Y10T29/539
摘要： A device is provided for collapsing a stented bioprosthetic valve, including first section and second sections, each spanning between first and second ends of the device. The second section of the device is associated with the first section to at least partially enclose an internal cavity formed by the first and second sections, the internal cavity tapering from an open insertion portion at a first end of the device to an open exit portion at a second end of the device. The insertion portion has a larger dimension than the exit portion. When the first section and second section are substantially enclosing the internal cavity, a stented bioprosthetic valve may be inserted into the insertion portion and collapsed as it is moved toward and through the exit portion. The valve may then be loaded on an apparatus for insertion into the body.

12. 发明申请

US20120078350A1 RETAINERS FOR TRANSCATHETER HEART VALVE DELIVERY SYSTEMS 有权
标题翻译： TRANSCATHETER心瓣输送系统的保持器
公开(公告)号：US20120078350A1
公开(公告)日：2012-03-29
申请号：US13180720
申请日：2011-07-12
申请人： Huisun Wang , Valerie J. Glazier , Alex Grafov
发明人： Huisun Wang , Valerie J. Glazier , Alex Grafov
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/962 , A61F2/966 , A61F2002/9522 , A61F2002/9665
摘要： A delivery device for an implantable medical device having at least one retention member at an end thereof includes a shaft extending in a longitudinal direction, an elongated sheath surrounding a longitudinal portion of the shaft, a compartment defined inside of the sheath and adapted to receive the medical device in an assembled condition, a retainer positioned at one end of the compartment, and at least one acceptance in the retainer adapted to receive the retention member of the medical device in the assembled condition. The sheath is slidable relative to the shaft in the longitudinal direction to uncover and deploy the medical device. The retainer may be rotatable relative to the shaft to reduce torsional forces in the medical device during delivery and deployment. The retainer may have at least one recess facing the compartment for receiving a strut at an end of a stent of the medical device.
摘要翻译：用于可植入医疗装置的输送装置在其一端具有至少一个保持构件，其包括沿纵向方向延伸的轴，围绕所述轴的纵向部分的细长护套，限定在护套内部并适于接纳处于组装状态的医疗设备，位于隔室的一端的保持器，以及保持器中的至少一个接受件，其适于在组装状态下接收医疗设备的保持构件。护套可以在纵向方向上相对于轴滑动以揭开和展开医疗装置。保持器可以相对于轴可旋转以减少在递送和展开期间医疗装置中的扭转力。保持器可以具有面向隔室的至少一个凹部，用于在医疗装置的支架的端部处接收支柱。

13. 发明授权

US10130418B2 Irrigated ablation electrode having smooth edges to minimize tissue char 有权
公开(公告)号：US10130418B2
公开(公告)日：2018-11-20
申请号：US12346634
申请日：2008-12-30
申请人： Huisun Wang , Sacha Hall
发明人： Huisun Wang , Sacha Hall
IPC分类号： A61B18/14 , A61B18/00
摘要： The invention relates to ablation catheter electrodes that solve in part the problem of tissue charring during radiofrequency ablation. The electrode assemblies of the invention include passageways that lead from the inner lumen of the assemblies to the surface of the assemblies, wherein the passageways have a smooth conjunction with the outer surface. These smooth conjunctions comprise rounded edges or are chamfered. In the case of rounded edges, the rounded edges can have fixed radii of about 0.002″ to about 0.008″.

14. 发明授权

US08778019B2 Staged deployment devices and method for transcatheter heart valve delivery 有权
标题翻译：分期部署装置和经导管心脏瓣膜输送的方法
公开(公告)号：US08778019B2
公开(公告)日：2014-07-15
申请号：US13234782
申请日：2011-09-16
申请人： Bradley Charles Knippel , Huisun Wang , Ralph Joseph Thomas , Jacob John Daly
发明人： Bradley Charles Knippel , Huisun Wang , Ralph Joseph Thomas , Jacob John Daly
IPC分类号： A61F2/84 , A61F2/24 , A61F2/966
CPC分类号： A61F2/2436 , A61F2/95 , A61F2/962 , A61F2/966 , A61F2002/9517 , A61F2002/9534
摘要： A delivery device for a collapsible heart valve includes an operating handle and a catheter assembly. The operating handle includes a frame defining a movement space therein, a carriage assembly moveable in a longitudinal direction within the movement space, and a coupler having locked and unlocked conditions, the coupler being operatively connected to the carriage assembly for movement therewith. The catheter assembly includes a shaft around which a valve-receiving compartment is defined, the shaft being operatively connected to one of the frame or the carriage assembly, and a distal sheath operatively connected to the carriage assembly for movement therewith between a closed condition adapted to maintain the valve in the compartment and an open condition adapted to fully deploy the valve.
摘要翻译：用于可折叠心脏瓣膜的递送装置包括操作手柄和导管组件。操作手柄包括限定其中的移动空间的框架，可在移动空间内沿纵向方向移动的滑架组件和具有锁定和解锁状态的联接器，联接器可操作地连接到滑架组件以与其一起运动。导管组件包括轴，围绕该轴限定了阀接收室，所述轴可操作地连接到框架或托架组件中的一个，以及可操作地连接到托架组件的远侧护套，用于在托架组件之间运动，该封闭状态适于将阀门保持在隔室中，并且适于完全展开阀门的打开状态。

15. 发明授权

US08721715B2 Preparation methods for transcatheter heart valve delivery systems 有权
标题翻译：经导管心脏瓣膜输送系统的制备方法
公开(公告)号：US08721715B2
公开(公告)日：2014-05-13
申请号：US13234761
申请日：2011-09-16
申请人： Huisun Wang
发明人： Huisun Wang
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/2427 , A61F2/243 , A61F2/2433 , A61F2/95 , A61F2/962 , A61F2/966
摘要： A delivery device for a collapsible prosthetic heart valve includes a support shaft around which a compartment is defined, an inner shaft extending through the support shaft and adapted to slide relative to the support shaft along a longitudinal axis thereof, the inner shaft having a lumen therethrough, and a distal sheath operatively connected at a distal end to the inner shaft and slidable therewith. The compartment may receive the valve in an assembled condition, and may be selectively covered and uncovered by the distal sheath. A first flow path may provide flow communication between the lumen of the inner shaft and the compartment.
摘要翻译：用于可折叠的假体心脏瓣膜的输送装置包括：支撑轴，隔室被定义在该支撑轴上;内轴，其延伸穿过所述支撑轴并适于沿着其纵向轴线相对于所述支撑轴滑动;所述内轴具有通过，以及远端护套，其在远端可操作地连接到内轴并且可与其滑动。隔室可以在组装状态下接收阀，并且可以被远侧护套选择性地覆盖和覆盖。第一流路可以在内轴的内腔和隔室之间提供流动连通。

16. 发明授权

US08597276B2 Implant delivery system with interlocked RX port orientation 有权
标题翻译：植入物交付系统具有互锁的RX端口方向
公开(公告)号：US08597276B2
公开(公告)日：2013-12-03
申请号：US11433328
申请日：2006-05-12
申请人： Khamla Vongphakdy , Huisun Wang , Adel Hashw , Lixiao Wang
发明人： Khamla Vongphakdy , Huisun Wang , Adel Hashw , Lixiao Wang
IPC分类号： A61M25/00
CPC分类号： A61M25/09 , A61F2/95 , A61F2/966 , A61F2002/9505 , A61F2002/9583 , A61F2002/9665 , Y10T29/49938
摘要： A medical implant delivery system maintains an orientation between a guidewire lumen of an inner member of the system and a rapid-exchange port in an outer member. The medical device is disposed intermediate the inner and outer members and in friction or pressure-fit contact with the outer member. Once the guidewire lumen of the inner member and the rapid exchange port of the outer member are oriented, the friction or pressure-fit operates to maintain the orientation until deployment of the medical implant. Orientation is further maintained by a telescoping coupling of the guide wire lumen with the rapid exchange port.
摘要翻译：医疗植入物递送系统保持系统的内部构件的导丝管腔和外部构件中的快速交换口之间的取向。医疗装置设置在内部构件和外部构件之间并且与外部构件摩擦或压配合接触。一旦内部构件的导丝腔和外部构件的快速交换口定向，则摩擦或压力配合操作以维持取向直到医疗植入物展开。通过导丝管腔与快速交换口的伸缩耦合来进一步保持定向。

17. 发明申请

US20120150175A1 Irrigated ablation electrode assembly and method for control of temperature 有权
标题翻译：灌注消融电极组件及温度控制方法
公开(公告)号：US20120150175A1
公开(公告)日：2012-06-14
申请号：US13402451
申请日：2012-02-22
申请人： Huisun Wang , Jeremy D. Dando , Harry Puryear
发明人： Huisun Wang , Jeremy D. Dando , Harry Puryear
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2017/00084 , A61B2018/00577 , A61B2218/002
摘要： Embodiments of the present invention provide an irrigated catheter having irrigation fluid directed at target areas where coagulation is more likely to occur so as to minimize blood coagulation and the associated problems. In one embodiment, an irrigated ablation electrode assembly for use with an irrigated catheter device comprises a proximal member having at least one passageway for a fluid with an outlet disposed at an external surface of the proximal member; and a distal member connected with the proximal member and having an external surface. The distal member includes an electrode. The external surface of the proximal member and the external surface of the distal member meet at an intersection. The at least one passageway of the proximal member is configured to direct a fluid flow through the outlet toward a region adjacent the intersection.
摘要翻译：本发明的实施方案提供了一种具有冲洗流体的灌溉导管，该冲洗流体被引导到更可能发生凝结的目标区域，从而使血液凝固和相关问题最小化。在一个实施例中，一种与灌溉导管装置一起使用的灌溉消融电极组件包括近端构件，其具有用于流体的至少一个通道，其中出口设置在近端构件的外表面处; 以及与所述近端构件连接并具有外表面的远侧构件。远侧构件包括电极。近端构件的外表面和远端构件的外表面在相交处相交。近端构件的至少一个通道构造成将流体流动引导通过邻近交叉点的区域。

18. 发明授权

US08167892B2 Adjustable and detached stent deployment device 有权
标题翻译：可调和分离的支架展开装置
公开(公告)号：US08167892B2
公开(公告)日：2012-05-01
申请号：US11321582
申请日：2005-12-29
申请人： Frederick Feller, III , Huisun Wang
发明人： Frederick Feller, III , Huisun Wang
IPC分类号： A61F11/00 , A61F2/06
CPC分类号： A61F2/95 , A61F2002/9517
摘要： The present disclosure is directed to a device for housing and retaining a delivery system for a self-expanding implant while providing means for actuating the delivery system.
摘要翻译：本公开涉及一种用于容纳和保持用于自膨胀植入物的输送系统的装置，同时提供用于致动输送系统的装置。

19. 发明授权

US07857810B2 Ablation electrode assembly and methods for improved control of temperature and minimization of coagulation and tissue damage 有权
标题翻译：消融电极组件和改善温度控制和最小化凝血和组织损伤的方法
公开(公告)号：US07857810B2
公开(公告)日：2010-12-28
申请号：US11434220
申请日：2006-05-16
申请人： Huisun Wang , Jeremy D. Dando , Dale Just , Allen P. Moore
发明人： Huisun Wang , Jeremy D. Dando , Dale Just , Allen P. Moore
IPC分类号： A61B18/14
CPC分类号： A61B18/148 , A61B2018/00011 , A61B2018/00744 , A61B2018/00791 , A61B2218/002
摘要： The present invention pertains to multiple piece irrigated ablation electrode assemblies wherein the irrigation channels are insulated or separated from at least one temperature sensing mechanism within the distal portion of the electrode assembly. The present invention further pertains to methods for improved assembly and accurate measurement and control of the electrode temperatures while effectively irrigating the device and target areas.
摘要翻译：本发明涉及多件式冲洗消融电极组件，其中冲洗通道与电极组件的远端部分内的至少一个温度感测机构绝缘或分离。本发明还涉及用于改进组装和准确测量和控制电极温度的方法，同时有效地冲洗装置和目标区域。

20. 发明申请

US20100305423A1 CATHETER HAVING DISTAL SEALING MEMBER 有权
标题翻译：具有远程密封会员的导管
公开(公告)号：US20100305423A1
公开(公告)日：2010-12-02
申请号：US12476539
申请日：2009-06-02
申请人： Huisun Wang , Dale Just
发明人： Huisun Wang , Dale Just
IPC分类号： A61M25/00 , A61B5/042
CPC分类号： A61B5/0422 , A61B1/0008 , A61M25/00 , A61M2025/0079
摘要： A catheter includes a proximal end, a distal end, a tubular member, and an inner member extending through the tubular member. The inner member is movable axially relative to the tubular member. The catheter also includes a seal member including a first portion and a second portion. The seal member extends between the tubular member and the inner member. The first portion of the seal member remains stationary relative to the tubular member, and the second portion of the seal member remains stationary relative to the inner member during relative axial movement between the tubular member and the inner member.
摘要翻译：导管包括近端，远端，管状构件和延伸穿过管状构件的内部构件。内部构件可相对于管状构件轴向移动。导管还包括密封构件，其包括第一部分和第二部分。密封构件在管状构件和内部构件之间延伸。密封构件的第一部分相对于管状构件保持固定，并且密封构件的第二部分在管状构件和内部构件之间的相对轴向移动期间相对于内部构件保持静止。

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