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11. 发明授权

US08394093B2 Irrigated ablation electrode assembly and method for control of temperature 有权
标题翻译：灌注消融电极组件及温度控制方法
公开(公告)号：US08394093B2
公开(公告)日：2013-03-12
申请号：US13402451
申请日：2012-02-22
申请人： Huisun Wang , Jeremy D. Dando , Harry Puryear
发明人： Huisun Wang , Jeremy D. Dando , Harry Puryear
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2017/00084 , A61B2018/00577 , A61B2218/002
摘要： Embodiments of the present invention provide an irrigated catheter having irrigation fluid directed at target areas where coagulation is more likely to occur so as to minimize blood coagulation and the associated problems. In one embodiment, , an irrigated ablation electrode assembly for use with an irrigated catheter device comprises a proximal member having at least one passageway for a fluid with an outlet disposed at an external surface of the proximal member; and a distal member connected with the proximal member and having an external surface. The distal member includes an electrode. The external surface of the proximal member and the external surface of the distal member meet at an intersection. The at least one passageway of the proximal member is configured to direct a fluid flow through the outlet toward a region adjacent the intersection.
摘要翻译：本发明的实施方案提供了一种具有冲洗流体的灌溉导管，该冲洗流体被引导到更可能发生凝结的目标区域，从而使血液凝固和相关问题最小化。在一个实施例中，一种与灌溉导管装置一起使用的灌溉消融电极组件包括近端构件，其具有用于流体的至少一个通道，其中出口设置在近端构件的外表面处; 以及与所述近端构件连接并具有外表面的远侧构件。远侧构件包括电极。近端构件的外表面和远端构件的外表面在相交处相交。近端构件的至少一个通道构造成将流体流动引导通过邻近交叉点的区域。

12. 发明授权

US08128621B2 Irrigated ablation electrode assembly and method for control of temperature 有权
公开(公告)号：US08128621B2
公开(公告)日：2012-03-06
申请号：US11948362
申请日：2007-11-30
申请人： Huisun Wang , Jeremy D. Dando , Harry Puryear
发明人： Huisun Wang , Jeremy D. Dando , Harry Puryear
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2017/00084 , A61B2018/00577 , A61B2218/002
摘要： Embodiments of the present invention provide an irrigated catheter having irrigation fluid directed at target areas where coagulation is more likely to occur so as to minimize blood coagulation and the associated problems. In one embodiment, an irrigated ablation electrode assembly for use with an irrigated catheter device comprises a proximal member having at least one passageway for a fluid with an outlet disposed at an external surface of the proximal member; and a distal member connected with the proximal member and having an external surface. The distal member includes an electrode. The external surface of the proximal member and the external surface of the distal member meet at an intersection. The at least one passageway of the proximal member is configured to direct a fluid flow through the outlet toward a region adjacent the intersection.

13. 发明授权

US10130418B2 Irrigated ablation electrode having smooth edges to minimize tissue char 有权
公开(公告)号：US10130418B2
公开(公告)日：2018-11-20
申请号：US12346634
申请日：2008-12-30
申请人： Huisun Wang , Sacha Hall
发明人： Huisun Wang , Sacha Hall
IPC分类号： A61B18/14 , A61B18/00
摘要： The invention relates to ablation catheter electrodes that solve in part the problem of tissue charring during radiofrequency ablation. The electrode assemblies of the invention include passageways that lead from the inner lumen of the assemblies to the surface of the assemblies, wherein the passageways have a smooth conjunction with the outer surface. These smooth conjunctions comprise rounded edges or are chamfered. In the case of rounded edges, the rounded edges can have fixed radii of about 0.002″ to about 0.008″.

14. 发明授权

US09408694B2 Tip for medical implant delivery system 有权
标题翻译：医疗植入物输送系统的提示
公开(公告)号：US09408694B2
公开(公告)日：2016-08-09
申请号：US13211447
申请日：2011-08-17
申请人： Huisun Wang , Valerie J. Glazier
发明人： Huisun Wang , Valerie J. Glazier
IPC分类号： A61F2/24 , A61F2/966
CPC分类号： A61F2/2436 , A61F2/2433 , A61F2/966 , A61F2250/0018 , A61F2250/0019
摘要： A delivery system for delivering and deploying a medical implant, such as a prosthetic heart valve, includes an elongated support member, a sheath, and a tip. The sheath is movable relative to the elongated support member between a distal position overlying the medical implant and a proximal position exposing the medical implant for release from the delivery system. The tip is attached to the elongated support member and is positioned at a distal end of the sheath when the sheath is in the distal position. The tip has a compressed condition and an expanded condition, and a maximum diameter in the expanded condition that is larger than the outer diameter of the sheath.
摘要翻译：用于递送和部署诸如假体心脏瓣膜的医疗植入物的递送系统包括细长的支撑构件，护套和尖端。护套可以在覆盖医疗植入物的远侧位置和暴露医疗植入物以远离输送系统的近端位置之间相对于细长支撑构件移动。当护套处于远侧位置时，尖端附接到细长的支撑构件并且定位在护套的远端。尖端具有压缩状态和膨胀状态，并且膨胀状态中的最大直径大于护套的外径。

15. 发明授权

US08778019B2 Staged deployment devices and method for transcatheter heart valve delivery 有权
标题翻译：分期部署装置和经导管心脏瓣膜输送的方法
公开(公告)号：US08778019B2
公开(公告)日：2014-07-15
申请号：US13234782
申请日：2011-09-16
申请人： Bradley Charles Knippel , Huisun Wang , Ralph Joseph Thomas , Jacob John Daly
发明人： Bradley Charles Knippel , Huisun Wang , Ralph Joseph Thomas , Jacob John Daly
IPC分类号： A61F2/84 , A61F2/24 , A61F2/966
CPC分类号： A61F2/2436 , A61F2/95 , A61F2/962 , A61F2/966 , A61F2002/9517 , A61F2002/9534
摘要： A delivery device for a collapsible heart valve includes an operating handle and a catheter assembly. The operating handle includes a frame defining a movement space therein, a carriage assembly moveable in a longitudinal direction within the movement space, and a coupler having locked and unlocked conditions, the coupler being operatively connected to the carriage assembly for movement therewith. The catheter assembly includes a shaft around which a valve-receiving compartment is defined, the shaft being operatively connected to one of the frame or the carriage assembly, and a distal sheath operatively connected to the carriage assembly for movement therewith between a closed condition adapted to maintain the valve in the compartment and an open condition adapted to fully deploy the valve.
摘要翻译：用于可折叠心脏瓣膜的递送装置包括操作手柄和导管组件。操作手柄包括限定其中的移动空间的框架，可在移动空间内沿纵向方向移动的滑架组件和具有锁定和解锁状态的联接器，联接器可操作地连接到滑架组件以与其一起运动。导管组件包括轴，围绕该轴限定了阀接收室，所述轴可操作地连接到框架或托架组件中的一个，以及可操作地连接到托架组件的远侧护套，用于在托架组件之间运动，该封闭状态适于将阀门保持在隔室中，并且适于完全展开阀门的打开状态。

16. 发明授权

US08721715B2 Preparation methods for transcatheter heart valve delivery systems 有权
标题翻译：经导管心脏瓣膜输送系统的制备方法
公开(公告)号：US08721715B2
公开(公告)日：2014-05-13
申请号：US13234761
申请日：2011-09-16
申请人： Huisun Wang
发明人： Huisun Wang
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/2427 , A61F2/243 , A61F2/2433 , A61F2/95 , A61F2/962 , A61F2/966
摘要： A delivery device for a collapsible prosthetic heart valve includes a support shaft around which a compartment is defined, an inner shaft extending through the support shaft and adapted to slide relative to the support shaft along a longitudinal axis thereof, the inner shaft having a lumen therethrough, and a distal sheath operatively connected at a distal end to the inner shaft and slidable therewith. The compartment may receive the valve in an assembled condition, and may be selectively covered and uncovered by the distal sheath. A first flow path may provide flow communication between the lumen of the inner shaft and the compartment.
摘要翻译：用于可折叠的假体心脏瓣膜的输送装置包括：支撑轴，隔室被定义在该支撑轴上;内轴，其延伸穿过所述支撑轴并适于沿着其纵向轴线相对于所述支撑轴滑动;所述内轴具有通过，以及远端护套，其在远端可操作地连接到内轴并且可与其滑动。隔室可以在组装状态下接收阀，并且可以被远侧护套选择性地覆盖和覆盖。第一流路可以在内轴的内腔和隔室之间提供流动连通。

17. 发明授权

US08597276B2 Implant delivery system with interlocked RX port orientation 有权
标题翻译：植入物交付系统具有互锁的RX端口方向
公开(公告)号：US08597276B2
公开(公告)日：2013-12-03
申请号：US11433328
申请日：2006-05-12
申请人： Khamla Vongphakdy , Huisun Wang , Adel Hashw , Lixiao Wang
发明人： Khamla Vongphakdy , Huisun Wang , Adel Hashw , Lixiao Wang
IPC分类号： A61M25/00
CPC分类号： A61M25/09 , A61F2/95 , A61F2/966 , A61F2002/9505 , A61F2002/9583 , A61F2002/9665 , Y10T29/49938
摘要： A medical implant delivery system maintains an orientation between a guidewire lumen of an inner member of the system and a rapid-exchange port in an outer member. The medical device is disposed intermediate the inner and outer members and in friction or pressure-fit contact with the outer member. Once the guidewire lumen of the inner member and the rapid exchange port of the outer member are oriented, the friction or pressure-fit operates to maintain the orientation until deployment of the medical implant. Orientation is further maintained by a telescoping coupling of the guide wire lumen with the rapid exchange port.
摘要翻译：医疗植入物递送系统保持系统的内部构件的导丝管腔和外部构件中的快速交换口之间的取向。医疗装置设置在内部构件和外部构件之间并且与外部构件摩擦或压配合接触。一旦内部构件的导丝腔和外部构件的快速交换口定向，则摩擦或压力配合操作以维持取向直到医疗植入物展开。通过导丝管腔与快速交换口的伸缩耦合来进一步保持定向。

18. 发明申请

US20130289698A1 RETAINERS FOR TRANSCATHETER HEART VALVE DELIVERY SYSTEMS 有权
标题翻译： TRANSCATHETER心瓣输送系统的保持器
公开(公告)号：US20130289698A1
公开(公告)日：2013-10-31
申请号：US13823337
申请日：2011-09-16
申请人： Huisun Wang , Valerie J. Glazier , Jacob John Daly
发明人： Huisun Wang , Valerie J. Glazier , Jacob John Daly
IPC分类号： A61F2/966
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2/966 , A61F2002/9665 , A61F2230/0054 , A61M2025/0681
摘要： A delivery device 10 for a collapsible prosthetic heart valve includes a catheter assembly 16 including a shaft 26 around which a compartment 23 is defined, the compartment 23 being adapted to receive the valve in an assembled condition, and a retainer 30 including a pusher 32 and a holder 34 adapted to retain a stent portion 106 of the valve. The catheter assembly 16 also includes a distal sheath 24 adapted to selectively cover and uncover the compartment 23 and the valve, the distal sheath 24 extending around the shaft 26 at least when the distal sheath 24 covers the compartment 23. The pusher 32 includes one or more recesses 40 in a retention edge 33 thereof, each recess 40 being adapted to receive a junction 107 at an end of the stent portion 106 of the valve. The holder 34 includes one or more elongated ribs 50, each rib 50 being adapted to fit into a cell opening 108 of the stent portion 106 of the valve.
摘要翻译：用于可折叠的假体心脏瓣膜的输送装置10包括导管组件16，导管组件16包括轴26，隔室23围绕该轴26被限定，隔室23适于在组装状态下容纳阀，以及保持器30，其包括推动器32和适于保持阀的支架部分106的保持器34。导管组件16还包括远端护套24，其适于选择性地覆盖和露出隔室23和瓣膜，至少当远端护套24覆盖隔室23时，远侧护套24围绕轴26延伸。推动器32包括一个或在其保持边缘33中具有更多的凹部40，每个凹部40适于在瓣膜的支架部分106的端部处容纳接合部107。保持器34包括一个或多个细长肋50，每个肋50适于装配到瓣膜的支架部分106的细胞开口108中。

19. 发明授权

US08167892B2 Adjustable and detached stent deployment device 有权
标题翻译：可调和分离的支架展开装置
公开(公告)号：US08167892B2
公开(公告)日：2012-05-01
申请号：US11321582
申请日：2005-12-29
申请人： Frederick Feller, III , Huisun Wang
发明人： Frederick Feller, III , Huisun Wang
IPC分类号： A61F11/00 , A61F2/06
CPC分类号： A61F2/95 , A61F2002/9517
摘要： The present disclosure is directed to a device for housing and retaining a delivery system for a self-expanding implant while providing means for actuating the delivery system.
摘要翻译：本公开涉及一种用于容纳和保持用于自膨胀植入物的输送系统的装置，同时提供用于致动输送系统的装置。

20. 发明授权

US07857810B2 Ablation electrode assembly and methods for improved control of temperature and minimization of coagulation and tissue damage 有权
标题翻译：消融电极组件和改善温度控制和最小化凝血和组织损伤的方法
公开(公告)号：US07857810B2
公开(公告)日：2010-12-28
申请号：US11434220
申请日：2006-05-16
申请人： Huisun Wang , Jeremy D. Dando , Dale Just , Allen P. Moore
发明人： Huisun Wang , Jeremy D. Dando , Dale Just , Allen P. Moore
IPC分类号： A61B18/14
CPC分类号： A61B18/148 , A61B2018/00011 , A61B2018/00744 , A61B2018/00791 , A61B2218/002
摘要： The present invention pertains to multiple piece irrigated ablation electrode assemblies wherein the irrigation channels are insulated or separated from at least one temperature sensing mechanism within the distal portion of the electrode assembly. The present invention further pertains to methods for improved assembly and accurate measurement and control of the electrode temperatures while effectively irrigating the device and target areas.
摘要翻译：本发明涉及多件式冲洗消融电极组件，其中冲洗通道与电极组件的远端部分内的至少一个温度感测机构绝缘或分离。本发明还涉及用于改进组装和准确测量和控制电极温度的方法，同时有效地冲洗装置和目标区域。

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