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11. 发明申请

US20130015331A1 DEVICE AND METHOD FOR DETECTING LIGHT 审中-公开
标题翻译：用于检测光的装置和方法
公开(公告)号：US20130015331A1
公开(公告)日：2013-01-17
申请号：US13545999
申请日：2012-07-11
申请人： Holger Birk , Volker Seyfried
发明人： Holger Birk , Volker Seyfried
IPC分类号： G01J1/44
CPC分类号： G01J3/027 , G01J1/0228 , G01J1/18 , G01J1/44 , G01J3/2803 , G01J3/36
摘要： A device for detecting light includes at least one silicon photomultiplier (SiPM) having an array of a plurality of single-photon avalanche diodes (SPADs), the array being larger in area than an incident light. The device is configured so as to at least one of activate and analyze only the SPADs upon which a specific minimum intensity of light impinges.
摘要翻译：用于检测光的装置包括具有多个单光子雪崩二极管（SPAD）的阵列的至少一个硅光电倍增管（SiPM），该阵列的面积大于入射光。该设备被配置为仅激活和分析仅具有特定的最小光强度的SPAD的至少一个。

12. 发明授权

US08319970B2 Device and method for beam adjustment in an optical beam path 有权
标题翻译：光束路径中光束调整的装置和方法
公开(公告)号：US08319970B2
公开(公告)日：2012-11-27
申请号：US12073360
申请日：2008-03-04
申请人： Holger Birk , Marcus Dyba , Hilmar Gugel , Volker Seyfried
发明人： Holger Birk , Marcus Dyba , Hilmar Gugel , Volker Seyfried
IPC分类号： G01N21/55
CPC分类号： G02B21/06
摘要： A device for beam adjustment in an optical beam path, having at least two mutually independent light sources providing respective beams of a high or extremely high resolution microscope, the beams of the light sources superposed in a common illumination beam path. The device includes a calibration sample with the aid of which the pupil position and/or focal position of the beams can be checked. The device also includes a sample holder arranged to bring the calibration sample into and out of the common illumination beam path at the site or in the vicinity of an intermediate image. A corresponding method is described. In accordance with the device and method, it is possible to undertake the beam adjustment independently of the actual use, that is to say, in the case of a high resolution microscope, independently of the examination sample and/or the recording of images.
摘要翻译：一种用于光束路径中的光束调节的装置，具有至少两个相互独立的光源，其提供高分辨率或极高分辨率显微镜的各个光束，所述光源的光束叠加在公共照明光束路径中。该装置包括校准样品借助于此可以检查光束的光瞳位置和/或焦点位置。该装置还包括样本保持器，其被布置成使得校准样品进入和离开中间图像的位置处或附近的公共照明光束路径。描述相应的方法。根据该装置和方法，可以独立于实际使用进行光束调节，也就是说，在高分辨率显微镜的情况下，独立于检查样本和/或图像的记录。

13. 发明申请

US20110304900A1 ACOUSTO-OPTICAL SYSTEM, MICROSCOPE AND METHOD OF USE OF THE ACOUSTO-OPTICAL SYSTEM 有权
标题翻译：光学系统，显微镜和使用光学系统的方法
公开(公告)号：US20110304900A1
公开(公告)日：2011-12-15
申请号：US13151055
申请日：2011-06-01
申请人： Bernd Widzgowski , Holger Birk , Volker Seyfried
发明人： Bernd Widzgowski , Holger Birk , Volker Seyfried
IPC分类号： G02F1/11 , G02F1/33 , G02F1/00
CPC分类号： G02F1/113 , G02B21/0032 , G02B21/0076
摘要： An acousto-optical system is described comprising at least one acousto-optical element having at least one transducer that is attached to a crystal, a driver unit for generating at least one acoustic signal for driving acousto-optical elements modifying light transmitted through the acousto-optical element and comprising at least one digital data processing unit, at least one digital-to-analog converter transforming the digital combination signal into an initial analog driver signal, and an amplifier for amplifying the initial analog driver signal to become said analog electronic driver signal. Further, a microscope and a method of operating the acousto-optical element is are described. Various objectives are achieved like more flexibility, real time compensation for non-linearity and reducing the number, size, costs and energy consumption of electronic components.
摘要翻译：描述了一种声光学系统，其包括至少一个具有至少一个连接到晶体的换能器的声光元件，驱动单元，用于产生用于驱动声光元件的至少一个声信号，所述声光信号修改透过声 - 光学元件，并且包括至少一个数字数据处理单元，将数字组合信号变换为初始模拟驱动器信号的至少一个数模转换器，以及用于放大初始模拟驱动器信号以成为所述模拟电子驱动器信号的放大器。此外，描述了显微镜和操作声光元件的方法。实现了各种目标，如更灵活，非线性的实时补偿和减少电子元件的数量，尺寸，成本和能耗。

14. 发明申请

US20100214654A1 APPARATUS FOR THE DETECTION OF LIGHT IN A SCANNING MICROSCOPE 有权
标题翻译：用于在扫描显微镜中检测光的装置
公开(公告)号：US20100214654A1
公开(公告)日：2010-08-26
申请号：US12600646
申请日：2008-05-06
申请人： Holger Birk , Volker Seyfried
发明人： Holger Birk , Volker Seyfried
IPC分类号： G01J1/44 , G01N21/00 , G01N21/55 , G01J1/58 , G02B21/06 , H01L27/146
CPC分类号： G01J1/44 , G01J1/46 , G01J3/2803 , G02B21/0032 , G02B21/0096 , H01L31/107
摘要： A light detector for use in a line scanning microscope and a microscope comprising such a light detector are described. The light detector comprises—a line array of avalanche semiconductor detectors; and an electronic trigger circuit that is adapted to operate the avalanche semiconductor detectors in at least one of a Geiger mode with internal charge amplification and in a linear mode. The trigger circuit further comprises a parallel counter that is designed to read out in parallel light pulses detected by the avalanche semiconductor detectors. The parallel counter is adapted to accumulate the light pulses detected by the avalanche semiconductor detectors over a preset counting time.
摘要翻译：描述在线扫描显微镜中使用的光检测器和包括这种光检测器的显微镜。光检测器包括 - 雪崩半导体检测器的线阵列; 以及电子触发电路，其适于以具有内部电荷放大和线性模式的Geiger模式中的至少一个来操作雪崩半导体检测器。触发电路还包括并行计数器，其被设计为平行地读出由雪崩半导体检测器检测到的光脉冲。并行计数器适于在预设的计数时间内积累由雪崩半导体检测器检测的光脉冲。

15. 发明授权

US09450118B2 Detector apparatus 有权
标题翻译：检测仪
公开(公告)号：US09450118B2
公开(公告)日：2016-09-20
申请号：US14238849
申请日：2012-08-15
申请人： Bernd Widzgowski , Volker Seyfried , Holger Birk , Frank Schreiber
发明人： Bernd Widzgowski , Volker Seyfried , Holger Birk , Frank Schreiber
IPC分类号： H01J40/16 , H01L31/024 , H01J40/02 , H01J43/02 , H01J43/28
CPC分类号： H01L31/024 , H01J40/02 , H01J40/16 , H01J43/02 , H01J43/28
摘要： A detector apparatus that is embodied to receive light and to generate electrical signals has a housing and a detector arranged in the housing. The detector includes a light sensor that is embodied to receive light and to release electrons. The light sensor is at a lower electrical potential level than the housing; and that the detector is in thermally conductive contact with the housing via an electrically insulating intermediate arrangement, the thermal conduction direction inside the housing being opposite to the light propagation direction of the light to be detected.
摘要翻译：体现为接收光并产生电信号的检测器装置具有设置在壳体中的壳体和检测器。检测器包括被实现为接收光并释放电子的光传感器。光传感器处于比壳体更低的电位电平; 并且检测器经由电绝缘的中间布置与壳体导热接触，壳体内部的热传导方向与待检测光的光传播方向相反。

16. 发明申请

US20140306098A1 DETECTOR APPARATUS 有权
标题翻译：检测仪器
公开(公告)号：US20140306098A1
公开(公告)日：2014-10-16
申请号：US14238849
申请日：2012-08-15
申请人： Bernd Widzgowski , Volker Seyfried , Holger Birk , Frank Schreiber
发明人： Bernd Widzgowski , Volker Seyfried , Holger Birk , Frank Schreiber
IPC分类号： H01L31/024 , H01J40/02
CPC分类号： H01L31/024 , H01J40/02 , H01J40/16 , H01J43/02 , H01J43/28
摘要： A detector apparatus that is embodied to receive light and to generate electrical signals has a housing and a detector arranged in the housing. The detector includes a light sensor that is embodied to receive light and to release electrons. The light sensor is at a lower electrical potential level than the housing; and that the detector is in thermally conductive contact with the housing via an electrically insulating intermediate arrangement, the thermal conduction direction inside the housing being opposite to the light propagation direction of the light to be detected.
摘要翻译：体现为接收光并产生电信号的检测器装置具有设置在壳体中的壳体和检测器。检测器包括被实现为接收光并释放电子的光传感器。光传感器处于比壳体更低的电位电平; 并且检测器经由电绝缘的中间布置与壳体导热接触，壳体内部的热传导方向与待检测光的光传播方向相反。

17. 发明授权

US08503076B2 Apparatus for the detection of light in a scanning microscope 有权
标题翻译：用于在扫描显微镜中检测光的装置
公开(公告)号：US08503076B2
公开(公告)日：2013-08-06
申请号：US12600646
申请日：2008-05-06
申请人： Holger Birk , Volker Seyfried
发明人： Holger Birk , Volker Seyfried
IPC分类号： G02B21/00
CPC分类号： G01J1/44 , G01J1/46 , G01J3/2803 , G02B21/0032 , G02B21/0096 , H01L31/107
摘要： A light detector for use in a line scanning microscope and a microscope comprising such a light detector are described. The light detector comprises a line array of avalanche semiconductor detectors; and an electronic trigger circuit that is adapted to operate the avalanche semiconductor detectors in at least one of a Geiger mode with internal charge amplification and in a linear mode. The trigger circuit further comprises a parallel counter that is designed to read out in parallel light pulses detected by the avalanche semiconductor detectors. The parallel counter is adapted to accumulate the light pulses detected by the avalanche semiconductor detectors over a preset counting time.
摘要翻译：描述在线扫描显微镜中使用的光检测器和包括这种光检测器的显微镜。光检测器包括雪崩半导体检测器的线阵列; 以及电子触发电路，其适于以具有内部电荷放大和线性模式的Geiger模式中的至少一个来操作雪崩半导体检测器。触发电路还包括并行计数器，其被设计为平行地读出由雪崩半导体检测器检测到的光脉冲。并行计数器适于在预设的计数时间内积累由雪崩半导体检测器检测的光脉冲。

18. 发明申请

US20120130670A1 System and Method for Computer-Controlled Execution of at Least One Test in a Scanning Microscope 有权
标题翻译：在扫描显微镜中进行最少一次测试的计算机控制执行系统和方法
公开(公告)号：US20120130670A1
公开(公告)日：2012-05-24
申请号：US13302025
申请日：2011-11-22
申请人： Holger Birk , Volker Seyfried , Roland Moschel , Derek Webster , Harald Brueggemann , Mario Belzer
发明人： Holger Birk , Volker Seyfried , Roland Moschel , Derek Webster , Harald Brueggemann , Mario Belzer
IPC分类号： G06F19/00
CPC分类号： G02B21/008 , G02B21/365
摘要： The invention relates to a method and a system for central computer controlled execution of at least one test run in a scanning microscope, particularly a confocal microscope, wherein at least one first software module of an application software is tested. The invention achieves the aim by a network made of individual scanning microscope clients and a central server. The clients can be contacted via a network interface and are administered in a central directory in the server. The application software for the individual components of a scanning microscope is made of individual software modules, each associated with a potential test. In order to be able to perform the various tests, the scanning microscope clients have been equipped on the hardware side with additional sensors and components that allow various operating parameters to be determined.
摘要翻译：本发明涉及一种用于中央计算机控制执行扫描显微镜，特别是共焦显微镜中的至少一个测试运行的方法和系统，其中测试应用软件的至少一个第一软件模块。本发明通过由单独的扫描显微镜客户端和中央服务器构成的网络实现了目的。可以通过网络接口联系客户端，并在服务器的中央目录中进行管理。扫描显微镜的各个组件的应用软件由单独的软件模块组成，每个软件模块都与潜在测试相关联。为了能够进行各种测试，扫描显微镜客户端已经在硬件方面配备了额外的传感器和组件，可以确定各种操作参数。

19. 发明申请

US20060219881A1 Microscope 审中-公开
标题翻译：显微镜
公开(公告)号：US20060219881A1
公开(公告)日：2006-10-05
申请号：US11358253
申请日：2006-02-21
申请人： Rafael Storz , Holger Birk , Heinrich Ulrich , Peter Euteneuer
发明人： Rafael Storz , Holger Birk , Heinrich Ulrich , Peter Euteneuer
IPC分类号： H01J5/16
CPC分类号： G02B21/0036
摘要： A microscope includes a scanning head including a scanning device for a light beam. A scanning tube lens is coupled to the scanning head. The scanning head may be a scanning head of a scanning microscope. The scanning tube lens may be disposed inside the scanning head. The scanning tube lens may be adapted to an optical requirement of the scanning head.
摘要翻译：显微镜包括包括用于光束的扫描装置的扫描头。扫描管透镜与扫描头连接。扫描头可以是扫描显微镜的扫描头。扫描管透镜可以设置在扫描头的内部。扫描管透镜可适用于扫描头的光学要求。

20. 发明授权

US06611643B2 Illuminating device and microscope 有权
公开(公告)号：US06611643B2
公开(公告)日：2003-08-26
申请号：US09881046
申请日：2001-06-15
申请人： Holger Birk , Rafael Storz
发明人： Holger Birk , Rafael Storz
IPC分类号： G02B632
CPC分类号： G02B6/02376 , B82Y20/00 , G02B6/02366 , G02B6/02371 , G02B6/1225 , G02B6/2552 , G02B21/002 , G02B21/0032 , G02B21/0056 , G02B21/0064 , G02B21/0076 , G02B21/008 , G02B21/06 , G02F1/353 , H01S3/005 , H01S3/1625 , H01S3/1636
摘要： The invention discloses an illuminating device (1) having a laser (3) that emits a light beam (7), which is directed onto a microstructured optical element (13) that spectrally broadens the light from the laser. The laser (3) and the microstructured optical element (13) are arranged within the casing.

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