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11. 发明授权

US06799157B1 Method for improving pin compatibility in microcomputer emulation equipment 失效
标题翻译：提高微机仿真设备引脚兼容性的方法
公开(公告)号：US06799157B1
公开(公告)日：2004-09-28
申请号：US09532514
申请日：2000-03-21
申请人： Makoto Kudo , Hirofumi Terasawa , Yoshiyuki Miyayama
发明人： Makoto Kudo , Hirofumi Terasawa , Yoshiyuki Miyayama
IPC分类号： G06E760
CPC分类号： G06F17/5022
摘要： An objective is to provide a microcomputer, electronic equipment and emulation method which can realize the optimum circumstance of evaluation while saving the number of terminals. An external bus is shared between external and emulation memories. In the emulation mode, the access of CPU to an internal ROM is switched to the access of CPU to the emulation memory through an external bus. The emulation mode is turned ON or OFF through a mode selection terminal or mode selection register. The emulation memory is controlled by a control signal CNT2 different from a control signal CNT1 which controls the external memory. A memory read signal in CNT2 become active at a timing earlier than that of a memory read signal in CNT1. Thus, the instruction is fetched and decoded within one clock cycle. A mode selection terminal is further provided for selecting a mode of performing the boot from the emulation memory, internal ROM or external memory and a made of selecting OPT mode.
摘要翻译：目的是提供一种微电脑，电子设备和仿真方法，可以在节省终端数量的同时实现最佳的评估环境。外部总线在外部和仿真存储器之间共享。在仿真模式下，CPU对内部ROM的访问通过外部总线切换到CPU对仿真存储器的访问。仿真模式通过模式选择端子或模式选择寄存器打开或关闭。仿真存储器由与控制外部存储器的控制信号CNT1不同的控制信号CNT2控制。 CNT2中的存储器读取信号比在CNT1中的存储器读取信号的时间早一个时间被激活。因此，指令在一个时钟周期内获取和解码。还提供一种模式选择终端，用于从仿真存储器，内部ROM或外部存储器中选择执行引导的模式，并且选择OPT模式。

12. 发明授权

US5770605A Method for treating leukemia with a hexa-cyclic compound 失效
标题翻译：用六环化合物治疗白血病的方法
公开(公告)号：US5770605A
公开(公告)日：1998-06-23
申请号：US811239
申请日：1997-03-03
申请人： Hirofumi Terasawa , Akio Ejima , Satoru Ohsuki , Kouichi Uoto
发明人： Hirofumi Terasawa , Akio Ejima , Satoru Ohsuki , Kouichi Uoto
IPC分类号： C07D491/22 , C07D495/22 , A61K31/47
CPC分类号： C07D491/22 , C07D495/22
摘要： A novel hexa-cyclic compound, a derivative of camptothecin, of the general formula: ##STR1## The compound is prepared from an aminoketone compound and a pyranoindolizine compound by the condensation-ring closing reaction. It is abundantly water-soluble, and has an excellent antitumor activity and a high degree of safety, and can be applied as an antitumor medicine for curing tumors of various kinds.
摘要翻译：一种新颖的六环化合物，喜树碱的衍生物，具有以下通式：该化合物通过缩合闭合反应由氨基酮化合物和吡喃并吲哚化合物制备。水溶性丰富，具有优异的抗肿瘤活性和高度的安全性，可用作治疗各种肿瘤的抗肿瘤药物。

13. 发明申请

US20080244138A1 MICROCOMPUTER 审中-公开
公开(公告)号：US20080244138A1
公开(公告)日：2008-10-02
申请号：US12053194
申请日：2008-03-21
申请人： Hirofumi Terasawa
发明人： Hirofumi Terasawa
IPC分类号： G06F13/24
CPC分类号： G06F13/24
摘要： A microcomputer includes a plurality of processing circuits for executing a plurality of interrupt processes each corresponding to one of a first plurality of causes) a cause register circuit for representing whether each of the first plurality of causes has been solved or unsolved, a processing circuit selection register for defining a plurality of correspondences each between one of the first plurality of causes and one of the plurality of processing circuits responsible to execute one the interrupt processes corresponding to the one of the first plurality of causes, and for outputting, in response to occurrence of one of the causes, to the plurality of processing circuits an interrupt signal representing that one of the interrupt processes should be executed, a vector signal indicating an area in which a content of the one of the interrupt processes corresponding to the one of the causes, and a first selection signal representing which one of the processing circuits should execute the one of the interrupt processes corresponding to the one of the causes, and a processing circuit selection circuit for outputting, in response to the first selection signal, to the processing circuit indicated by the first selection signal, a second selection signal representing that the processing circuit is selected.
摘要翻译：微计算机包括多个处理电路，用于执行各自对应于第一多个原因中的一个的多个中断处理）用于表示第一多个原因中的每一个是否已被解决或未解决的原因寄存器电路，处理电路选择注册用于在多个原因中的一个原因和多个处理电路中的一个处理电路之间定义多个对应关系，负责执行与第一多个原因之一相对应的中断处理，并且响应于发生而输出其中一个原因是向多个处理电路发送一个表示应该执行中断处理中的一个中断信号的向量信号，指示其中一个中断处理的内容对应于其中一个原因的区域以及表示哪个处理电路应该执行t的第一选择信号它是与原因之一相对应的一个中断处理，以及一个处理电路选择电路，用于响应于第一选择信号，向由第一选择信号指示的处理电路输出表示处理的第二选择信号选择电路。

14. 发明授权

US06552197B2 Condensed-hexacyclic compounds and a process therefor 失效
标题翻译：缩合六环化合物及其制备方法
公开(公告)号：US06552197B2
公开(公告)日：2003-04-22
申请号：US09876945
申请日：2001-06-11
申请人： Shinji Kamihara , Kazuaki Kanai , Shigeru Noguchi , Hirofumi Terasawa , Hiroaki Kitaoka
发明人： Shinji Kamihara , Kazuaki Kanai , Shigeru Noguchi , Hirofumi Terasawa , Hiroaki Kitaoka
IPC分类号： C07D47100
CPC分类号： C07D491/22 , Y02P20/55
摘要： Disclosed are a process for the preparation of a compound represented by the formula (1), which comprises treating a compound represented by the formula (2) with methanesulfonic acid and then subjecting the thus-treated compound to recrystallization; and Compound (1) so obtained. This Compound (1) is free of hygroscopicity, excellent in filterability and solubility and easy in handling. Furthermore, according to the preparation process of the present invention, an unnecessary isomer can be converted into the target one and separation of the target isomer can be conducted easily.
摘要翻译：公开了一种制备式（1）表示的化合物的方法，其包括用甲磺酸处理由式（2）表示的化合物，然后使经过处理的化合物进行重结晶; 和化合物（1）。该化合物（1）不具有吸湿性，过滤性和溶解性优异，易于处理。此外，根据本发明的制备方法，可以将不必要的异构体转化成目标物，并且可以容易地进行目标异构体的分离。

15. 发明授权

US06504029B1 Condensed-hexacyclic compounds and a process therefor 失效
公开(公告)号：US06504029B1
公开(公告)日：2003-01-07
申请号：US08501933
申请日：1995-07-13
申请人： Shinji Kamihara , Kazuaki Kanai , Shigeru Noguchi , Hirofumi Terasawa , Hiroaki Kitaoka
发明人： Shinji Kamihara , Kazuaki Kanai , Shigeru Noguchi , Hirofumi Terasawa , Hiroaki Kitaoka
IPC分类号： C07D47116
CPC分类号： C07D491/22 , Y02P20/55
摘要： Disclosed are a process for the preparation of a compound represented by the formula (1), which comprises treating a compound represented by the formula (2) with methanesulfonic acid and then subjecting the thus-treated compound to recrystallization; and Compound (1) so obtained. This Compound (1) is free of hygroscopicity, excellent in filterability and solubility and easy in handling. Furthermore, according to the preparation process of the present invention, an unnecessary isomer can be converted into the target one and separation of the target isomer can be conducted easily.

16. 发明授权

US5834476A Hexa-cyclic compound 失效
标题翻译：六环化合物
公开(公告)号：US5834476A
公开(公告)日：1998-11-10
申请号：US989420
申请日：1997-12-12
申请人： Hirofumi Terasawa , Akio Ejima , Satoru Ohsuki , Kouichi Uoto
发明人： Hirofumi Terasawa , Akio Ejima , Satoru Ohsuki , Kouichi Uoto
IPC分类号： C07D491/22 , C07D495/22 , A61K31/40 , A61K31/435 , C07D471/22
CPC分类号： C07D491/22 , C07D495/22
摘要： A novel hexa-cyclic compound, a derivative of camptothecin, of the general formula: ##STR1## The compound is prepared from an aminoketone compound and a pyranoindolizine compound by the condensation-ring closing reaction. It is abundantly water-soluble, and has an excellent antitumour activity and a high degree of safety, and can be applied as an antitumour medicine for curing tumors of various kinds.
摘要翻译：一种新颖的六环化合物，喜树碱的衍生物，具有以下通式：该化合物通过缩合闭合反应由氨基酮化合物和吡喃并吲哚化合物制备。水溶性丰富，抗肿瘤活性优良，安全性高，可用作治疗各种肿瘤的抗肿瘤药物。

17. 发明授权

US5061795A Hexa-cyclic compound 失效
标题翻译：十六烷环化合物
公开(公告)号：US5061795A
公开(公告)日：1991-10-29
申请号：US457921
申请日：1989-12-27
申请人： Hiroaki Tagawa , Masamichi Sugimori , Hirofumi Terasawa , Akio Ejima , Satoru Ohsuki
发明人： Hiroaki Tagawa , Masamichi Sugimori , Hirofumi Terasawa , Akio Ejima , Satoru Ohsuki
IPC分类号： C07D471/22 , C07D491/22 , C07D495/22
CPC分类号： C07D495/22 , C07D471/22 , C07D491/22
摘要： A novel hexa-cyclic compound, a derivative of camptothecin, of the general formura: ##STR1## The compound is prepared from an aminoketone compound and a pyranoindolizine compound through Friedlaender reaction. It has an excellent antitumour activity and a high degree of safety, and can be applied as an antitumour medicine for curing tumors of various kinds.

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