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11. 发明授权

US06887263B2 Valved connector assembly and sterility barriers for heat exchange catheters and other closed loop catheters 有权
标题翻译：用于热交换导管和其他闭环导管的阀门连接器组件和无菌屏障
公开(公告)号：US06887263B2
公开(公告)日：2005-05-03
申请号：US10273637
申请日：2002-10-18
申请人： Jefferey C. Bleam , George Tsai
发明人： Jefferey C. Bleam , George Tsai
IPC分类号： A61F7/12 , A61M5/172 , A61M5/44 , A61F7/00
CPC分类号： A61F7/12 , A61B90/40 , A61F2007/126 , A61M5/1723 , A61M5/445 , A61M25/1002 , A61M2025/1072 , A61M2205/36
摘要： A connector assembly for catheters having closed loop flow circuits, such as some balloon catheters and heat exchange catheters. The connector assembly comprises first and second connector bodies that may be connected and disconnected from one another. When the connector bodies are disconnected, a syringe or negative pressure source may be attached to withdraw residual fluid from the catheter's closed loop circuit and to deflate any expandable portion of the closed loop circuit (e.g., balloon or expandable heat exchanger). A one way flow valve prevents make up air or other fluid from entering the catheter while the negative pressure is being applied. Also disclosed are sterility barrier assemblies for all types of catheters. Such sterility barrier assemblies are operative to prevent contamination of the portion of a catheter that remains outside of a patient's body so that the catheter may subsequently be further advanced into the patient's body without introducing microbes or other contaminants into the patient's body.
摘要翻译：用于具有闭环流动回路的导管的连接器组件，例如一些气囊导管和热交换导管。连接器组件包括可以彼此连接和断开的第一和第二连接器本体。当连接器主体断开时，可以连接注射器或负压源以从导管的闭环回路中抽出残余流体并使闭合回路的任何可膨胀部分（例如球囊或可膨胀热交换器）放气。单向流量阀防止在施加负压时补充空气或其它流体进入导管。还公开了用于所有类型的导管的无菌屏障组件。这种无菌屏障组件可操作以防止留在患者身体外部的导管部分的污染，使得导管随后可以进一步前进到患者体内，而不会将微生物或其它污染物引入患者体内。

12. 发明授权

US08262716B2 Valved connector assembly and sterility barriers for heat exchange catheters and other closed loop catheters 有权
标题翻译：用于热交换导管和其他闭环导管的阀门连接器组件和无菌屏障
公开(公告)号：US08262716B2
公开(公告)日：2012-09-11
申请号：US12416028
申请日：2009-03-31
申请人： Jefferey C. Bleam , George Tsai
发明人： Jefferey C. Bleam , George Tsai
IPC分类号： A61F7/12
CPC分类号： A61F7/12 , A61B90/40 , A61F2007/126 , A61M5/1723 , A61M5/445 , A61M25/1002 , A61M2025/1072 , A61M2205/36
摘要： A connector assembly for catheters having closed loop flow circuits, such as some balloon catheters and heat exchange catheters. The connector assembly comprises first and second connector bodies that may be connected and disconnected from one another. When the connector bodies are disconnected, a syringe or negative pressure source may be attached to withdraw residual fluid from the catheter's closed loop circuit and to deflate any expandable portion of the closed loop circuit (e.g., balloon or expandable heat exchanger). A one way flow valve prevents make up air or other fluid from entering the catheter while the negative pressure is being applied. Also disclosed are sterility barrier assemblies for all types of catheters. Such sterility barrier assemblies are operative to prevent contamination of the portion of a catheter that remains outside of a patient's body so that the catheter may subsequently be further advanced into the patient's body without introducing microbes or other contaminants into the patient's body.
摘要翻译：用于具有闭环流动回路的导管的连接器组件，例如一些气囊导管和热交换导管。连接器组件包括可以彼此连接和断开的第一和第二连接器本体。当连接器主体断开时，可以连接注射器或负压源以从导管的闭环回路中抽出残留流体并使闭合回路的任何可膨胀部分（例如球囊或可膨胀热交换器）放气。单向流量阀防止在施加负压时补充空气或其它流体进入导管。还公开了用于所有类型的导管的无菌屏障组件。这种无菌屏障组件可操作以防止留在患者身体外部的导管部分的污染，使得导管随后可以进一步前进到患者体内，而不会将微生物或其它污染物引入患者体内。

13. 发明申请

US20090247963A1 VALVED CONNECTOR ASSEMBLY AND STERILITY BARRIERS FOR HEAT EXCHANGE CATHETERS AND OTHER CLOSED LOOP CATHETERS 有权
标题翻译：用于换热器和其他闭合环路的阀门连接器总成和不可穿制障碍物
公开(公告)号：US20090247963A1
公开(公告)日：2009-10-01
申请号：US12416028
申请日：2009-03-31
申请人： Jefferey C. Bleam , George Tsai
发明人： Jefferey C. Bleam , George Tsai
IPC分类号： A61M25/16 , A61M39/22 , A61F7/12
CPC分类号： A61F7/12 , A61B90/40 , A61F2007/126 , A61M5/1723 , A61M5/445 , A61M25/1002 , A61M2025/1072 , A61M2205/36
摘要： A connector assembly for catheters having closed loop flow circuits, such as some balloon catheters and heat exchange catheters. The connector assembly comprises first and second connector bodies that may be connected and disconnected from one another. When the connector bodies are disconnected, a syringe or negative pressure source may be attached to withdraw residual fluid from the catheter's closed loop circuit and to deflate any expandable portion of the closed loop circuit (e.g., balloon or expandable heat exchanger). A one way flow valve prevents make up air or other fluid from entering the catheter while the negative pressure is being applied. Also disclosed are sterility barrier assemblies for all types of catheters. Such sterility barrier assemblies are operative to prevent contamination of the portion of a catheter that remains outside of a patient's body so that the catheter may subsequently be further advanced into the patient's body without introducing microbes or other contaminants into the patient's body.
摘要翻译：用于具有闭环流动回路的导管的连接器组件，例如一些气囊导管和热交换导管。连接器组件包括可以彼此连接和断开的第一和第二连接器本体。当连接器主体断开时，可以连接注射器或负压源以从导管的闭环回路中抽出残余流体并使闭合回路的任何可膨胀部分（例如球囊或可膨胀热交换器）放气。单向流量阀防止在施加负压时补充空气或其它流体进入导管。还公开了用于所有类型的导管的无菌屏障组件。这种无菌屏障组件可操作以防止留在患者身体外部的导管部分的污染，使得导管随后可以进一步前进到患者体内，而不会将微生物或其它污染物引入患者体内。

14. 发明授权

US6143016A Sheath and method of use for a stent delivery system 失效
标题翻译：护套和支架输送系统的使用方法
公开(公告)号：US6143016A
公开(公告)日：2000-11-07
申请号：US840487
申请日：1997-04-21
申请人： Jefferey C. Bleam , Andrew J. MacKenzie
发明人： Jefferey C. Bleam , Andrew J. MacKenzie
IPC分类号： A61M25/00 , A61F2/00 , A61F2/82 , A61M25/01 , A61M29/00
CPC分类号： A61F2/958 , A61F2002/826 , A61F2250/0097
摘要： An apparatus and method for deploying one or more stents within a body lumen comprises a substantially tubular sheath configured for slidable movement over a catheter shaft and configured to receive a stent over a flexible, expandable distal portion of the sheath. The sheath may comprise a part of a stent deployment system including a dilatation catheter (such as a balloon catheter), and one or more substantially tubular stents positioned in their delivery configurations over the expandable distal portion of the sheath. The sheath preferably has a proximal portion that is configured so that a user may advance the sheath over the catheter by maneuvering the sheath proximal end. The substantially tubular stent is preferably a radially expandable stent having a delivery configuration and a deployed configuration.When the apparatus is introduced into a body lumen, the sheath is positioned on the catheter shaft such that the sheath distal portion bearing the stent is proximal of the catheter expandable member (e.g., balloon). Thus, the catheter expandable member may be used to dilate the body lumen without deploying the stent. After dilatation is completed, the sheath is advanced until the stent is positioned around the expandable member which is then expanded, thereby radially expanding and deploying the stent or stents.
摘要翻译：用于在体腔内部署一个或多个支架的装置和方法包括基本上管状的护套，其被配置为可在导管轴上滑动移动并且被配置为在护套的柔性，可扩张的远端部分上容纳支架。护套可以包括支架展开系统的一部分，该支架展开系统包括扩张导管（例如球囊导管），以及一个或多个基本上管状的支架，其定位在其在护套的可扩张远端部分上的输送构型。护套优选地具有近端部分，该近端部分构造成使得使用者可以通过操纵护套近端来将护套推进导管上。基本上管状的支架优选是具有输送构型和展开构造的径向可扩张的支架。当装置被引入体腔时，护套定位在导管轴上，使得支承支架的护套远端部分在导管可扩张构件（例如气囊）的近侧。因此，可以使用导管可扩张构件来扩张体腔而不展开支架。在扩张完成之后，护套前进，直到支架位于可膨胀构件周围，然后膨胀，从而径向扩张和展开支架或支架。

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