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11. 发明专利

CA2383871A1 A NOVEL BAP28 GENE AND PROTEIN 未知
公开(公告)号：CA2383871A1
公开(公告)日：2001-01-04
申请号：CA2383871
申请日：2000-06-23
申请人： GENSET SA
发明人： COHEN-AKENINE ANNICK , CHUMAKOV ILYA , BOUGUELERET LYDIE , BARRY CAROLINE
IPC分类号： C07K14/47 , C12N15/12 , C12Q1/68 , A01K67/027 , C12N5/10 , G01N33/50 , C12N15/63 , G01N33/68
摘要： The present invention is directed to BAP28 polypeptides, BAP28 cDNA sequence s encoding BAP28 polypeptides, to the genomic DNA sequence of the BAP28 gene a s well as to regulatory regions located at the 5'- and 3'-ends of the BAP28 coding region. The invention also deals with antibodies directed specificall y against such polypeptides that are useful as diagnostic reagents. The invention further encompasses biallelic markers of the BAP28 gene useful in genetic analysis. The invention concerns an association of the BAP28-related biallelic markers with prostate cancer. Therefore, the invention contemplate s the diagnostic and treatment methods of prostate cancer.

12. 发明专利

DK1129216T3 未知
公开(公告)号：DK1129216T3
公开(公告)日：2005-01-17
申请号：DK99954287
申请日：1999-11-10
申请人： GENSET SA
发明人： BLUMENFELD MARTA , SCHORK J NICHOLAS , ESSIOUX LAURENT , COHEN-AKENINE ANNICK , COHEN DANIEL
IPC分类号： G01N33/53 , C12N15/09 , C12Q1/68 , G01N33/566 , G06F17/30 , G06F19/18 , G06F19/22 , G06F19/24 , G06F19/00
摘要： The present invention relates to methods, software, and apparati for determining whether a genomic region harbors a gene associated with a detectable trait. In one embodiment, the present invention relates to a method of confirming that a genomic region harbors a gene associated with a detectable trait comprising the steps of identifying a candidate genomic region suspected of harboring the gene associated with the detectable trait, constructing a trait-associated distribution of association values using the biallelic markers in the candidate genomic region, identifying a plurality of biallelic markers in random genomic regions which are not suspected of harboring the gene associated with the detectable trait, constructing a random distribution of association values using the biallelic markers in the random genomic regions, comparing the trait-associated distribution of association values to the random distribution of association values, and determining whether the trait-associated distribution of association values and the random distribution of association values are significantly different from one another. In other embodiments, the present invention comprises software for performing the above method and devices comprising the software in a retrievable form.

13. 发明专利

AU4135600A Prostate cancer associated human fibronectin gene and biallelic markers 未知
公开(公告)号：AU4135600A
公开(公告)日：2000-10-16
申请号：AU4135600
申请日：2000-03-28
申请人： GENSET SA
发明人： BLUMENFELD MARTA , BOUGUELERET LYDIE , CHUMAKOV ILYA , COHEN-AKENINE ANNICK
IPC分类号： C12N15/12 , C12Q1/68 , C12Q1/6886 , C12N5/16 , G06F17/30

14. 发明专利

AU1069600A Methods, software and apparati for identifying genomic regions harboring a gene associated with a detectable trait 未知
公开(公告)号：AU1069600A
公开(公告)日：2000-05-29
申请号：AU1069600
申请日：1999-11-10
申请人： GENSET SA
发明人： SCHORK J NICHOLAS , ESSIOUX LAURENT , COHEN-AKENINE ANNICK , BLUMENFELD MARTA , COHEN DANIEL
IPC分类号： G01N33/53 , C12N15/09 , C12Q1/68 , G01N33/566 , G06F17/30 , G06F19/18 , G06F19/22 , G06F19/24 , G06F19/00
摘要： The present invention relates to methods, software, and apparati for determining whether a genomic region harbors a gene associated with a detectable trait. In one embodiment, the present invention relates to a method of confirming that a genomic region harbors a gene associated with a detectable trait comprising the steps of identifying a candidate genomic region suspected of harboring the gene associated with the detectable trait, constructing a trait-associated distribution of association values using the biallelic markers in the candidate genomic region, identifying a plurality of biallelic markers in random genomic regions which are not suspected of harboring the gene associated with the detectable trait, constructing a random distribution of association values using the biallelic markers in the random genomic regions, comparing the trait-associated distribution of association values to the random distribution of association values, and determining whether the trait-associated distribution of association values and the random distribution of association values are significantly different from one another. In other embodiments, the present invention comprises software for performing the above method and devices comprising the software in a retrievable form.

15. 发明专利

CA2348609A1 METHODS, SOFTWARE AND APPARATI FOR IDENTIFYING GENOMIC REGIONS HARBORING A GENE ASSOCIATED WITH A DETECTABLE TRAIT 未知
公开(公告)号：CA2348609A1
公开(公告)日：2000-05-18
申请号：CA2348609
申请日：1999-11-10
申请人： GENSET SA
发明人： SCHORK J NICHOLAS , COHEN-AKENINE ANNICK , BLUMENFELD MARTA , COHEN DANIEL , ESSIOUX LAURENT
IPC分类号： G01N33/53 , C12N15/09 , C12Q1/68 , G01N33/566 , G06F17/30 , G06F19/18 , G06F19/22 , G06F19/24 , G06F19/00
摘要： The present invention relates to methods, software, and apparati for determining whether a genomic region harbors a gene associated with a detectable trait. In one embodiment, the present invention relates to a meth od of confirming that a genomic region harbors a gene associated with a detectable trait comprising the steps of identifying a candidate genomic region suspected of harboring the gene associated with the detectable trait, constructing a trait-associated distribution of association values using the biallelic markers in the candidate genomic region, identifying a plurality o f biallelic markers in random genomic regions which are not suspected of harboring the gene associated with the detectable trait, constructing a rand om distribution of association values using the biallelic markers in the random genomic regions, comparing the trait-associated distribution of association values to the random distribution of association values, and determining whether the trait-associated distribution of association values and the rand om distribution of association values are significantly different from one another. In other embodiments, the present invention comprises software for performing the above method and devices comprising the software in a retrievable form.

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