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    • 15. 发明授权
    • Avermectin and avermectin monosaccharide derivatives substituted in the 4″-or 4′-position having pesticidal properties
    • 在4“ - 或4”位取代的具有杀虫性的阿维菌素和阿维菌素单糖衍生物
    • US07678740B2
    • 2010-03-16
    • US10543637
    • 2004-01-30
    • Thomas PitternaFiona Murphy KessabiPeter MaienfischJerome CassayreLaura QuarantaPierre Jung
    • Thomas PitternaFiona Murphy KessabiPeter MaienfischJerome CassayreLaura QuarantaPierre Jung
    • A01N25/26A01N43/02A01N43/04C07H17/08
    • A01N43/90C07H17/08
    • What is described are a compound of the formula (I) Wherein U is —N(R2)OR3 or —N+(O−)═C(RE)RZ); n is 0 or 1; X—Y is —CH═CH— or —CH2—CH2—; R1 is C1-C12alkyl, C3-C8cycloalkyl or C2-C12alkenyl; R2 and R3 are, for example; independently from each other, —Q, —C(═O)—Z—Q or —CN; RZ and RE are, independently from each other, —Q, —C(═O)—Z—Q or —CN; or RZ and RE together are a three- to seven membered alkylene or alkenylene bridge, which is unsubstituted or mono- to tri-substituted; Z is a bond, O or —NR4—; Q is H, C1-C12alkyl, C2-C12alkenyl, C2-C12alkynyl, C3-C12-Cycloalkyl, C5-C12-cycloalkenyl, aryl, or heterocyclyl, which are unsubstituted or mono- to pentasubstituted; R4 is for example H, C1-C8alkyl, hydroxy-C1-C8alkyl, C3-C8cycloalkyl or C2-C8alkenyl; or, if appropriate, an E/Z isomer, E/Z isomer mixture and/or tautomer thereof; a process for preparing these compounds, their isomers and tautomers and the use of these compounds, their isomers and tautomers; pesticidal compositions whose active compound is selected from these compounds and their tautomers; intermediates for the preparation of the said compounds of the formula (I), methods for the preparation of the compounds of the formula (I), and a method for controlling pests using these compositions.
    • 描述的是式(I)的化合物,其中U是-N(R 2)OR 3或-N +(O-)= C(RE)R Z); n为0或1; X-Y是-CH = CH-或-CH 2 -CH 2 - ; R1是C1-C12烷基,C3-C8环烷基或C2-C12链烯基; R2和R3例如是: 独立地为-Q,-C(= O)-Z-Q或-CN; RZ和RE彼此独立地为-Q,-C(= O)-Z-Q或-CN; 或RZ和RE一起是三至七元的亚烷基或亚烯基桥,其是未取代的或一至三取代的; Z是O或-NR4-键; Q是未被取代或被一取代或五取代的H,C 1 -C 12烷基,C 2 -C 12烯基,C 2 -C 12炔基,C 3 -C 12环烷基,C 5 -C 12 - 环烯基,芳基或杂环基, R4是例如H,C1-C8烷基,羟基-C1-C8烷基,C3-C8环烷基或C2-C8链烯基; 或者,如果合适的话,E / Z异构体,E / Z异构体混合物和/或其互变异构体; 制备这些化合物,其异构体和互变异构体的方法以及这些化合物,其异构体和互变异构体的用途; 活性化合物选自这些化合物及其互变异构体的杀虫组合物; 用于制备所述式(I)化合物的中间体,式(I)化合物的制备方法和使用这些组合物来控制害虫的方法。
    • 16. 发明申请
    • Avermectins and avermectin monosaccharides substituted in the 4'-and 4
    • 在4'和4“位具有杀虫性质的阿维菌素和阿维菌素单糖被取代
    • US20060094600A1
    • 2006-05-04
    • US10544281
    • 2004-02-03
    • Laura QuarantaThomas PitternaPeter MaienfischFiona Murphy KessabiJerome Cassayre
    • Laura QuarantaThomas PitternaPeter MaienfischFiona Murphy KessabiJerome Cassayre
    • A01N43/04A01N25/26C07H17/08
    • C07H17/08A01N43/90
    • What is described are a compound of the formula (I) wherein the bond of atoms C22 and C23 is a single or double bond; m is 0 or 1; n is 0, 1 or 2; p is 0 or 1; R1 is C1-C12-alkyl, C3-C8-cycloalkyl or C2-C12alkenyl; R2 is for example H, C1-C12-alkyl, C1-C12-haloalkyl or C1-C12-hydroxyalkyl; or together with R4 form with the carbon to which they are bound for example a three- to seven-membered ring; R3 is for example H, C1-C12-alkyl, halogen, halo-C1-C2alkyl, CN, NO2 or C3-C8-cycloalkyl; R4 has the same meanings as R2; R5 and R6 independently of each other are for example H, C1-C12-alkyl, CN, NO2, OH, SH, halogen, halo-C1-C2alkyl or C3-C8cycloalkyl; or, if appropriate, an E/Z isomer, E/Z isomer mixture and/or tautomer thereof, in each case in free form or in salt form a process for preparing and using these compounds and their tautomers; pesticides whose active compound is selected from these compounds and their tautomers; and a process for preparing these compounds and compositions, and the use of these compounds and compositions.
    • 描述的是式(I)的化合物,其中原子C 22和C 23的键是单键或双键; m为0或1; n为0,1或2; p为0或1; R 1是C 1 -C 12 - 烷基,C 3 -C 8亚烷基,C 3 -C 12 - 烷基,C 3 -C 12 - 环烷基或C 2 -C 12链烯基; R 2是例如H,C 1 -C 12 - 烷基,C 1 -C 3 - 12个 - 卤代烷基或C 1 -C 12 - 羟基烷基; 或与R 4 S形成的碳与它们所键合的碳例如为三至七元环; R 3是例如H,C 1 -C 12 - 烷基,卤素,卤素-C 1 - C 2 -C 12烷基,CN,NO 2或C 3 -C 8 - 环烷基; R 4具有与R 2'相同的含义; R 5和R 6彼此独立地是例如H,C 1 -C 12 - 烷基, CN,NO 2,OH,SH,卤素,卤代-C 1 -C 2烷基或C 3 - -C 8环烷基; 或者如果适用,E / Z异构体,E / Z异构体混合物和/或其互变异构体在每种情况下以游离形式或盐形成用于制备和使用这些化合物及其互变异构体的方法; 活性化合物选自这些化合物及其互变异构体的农药; 以及制备这些化合物和组合物的方法,以及这些化合物和组合物的用途。
    • 18. 发明申请
    • Avermectins substituted in the 4
    • 在4“和4”位取代的阿维菌素具有杀虫特性
    • US20060154879A1
    • 2006-07-13
    • US10544274
    • 2004-02-03
    • Jerome CassayreHans ToblerThomas PitternaPeter MaienfischFiona Murphy KessabiLaura QuarantaOttmar Hueter
    • Jerome CassayreHans ToblerThomas PitternaPeter MaienfischFiona Murphy KessabiLaura QuarantaOttmar Hueter
    • A01N43/04C07H17/08
    • C07H17/08
    • What is described are a compound of the formula (I) Wherein A-B is —CH═CH— or —CH2—CH2—; n is 0 or 1; R1, is C1-C12alkyl, C3-C8cycloalkyl or C2-C12alkenyl; R2 and R3 for instance are either, (i) independently from each other for instance -Q, —C(═Y)-Q, or —C(═Y)—O-Q; or (ii) together form with the nitrogen atom to which they are bound a three- to seven-membered ring, (iii) together are ═C(R4)R5; R4 and R5 are, independently from each other, for instance -Q, —C(═Y)-Q, or —C(═Y)—O-Q; Y is O or S; Q is for instance H or unsubstituted or mono- to pentasubstituted C1-C12alkyl; or, if appropriate, an E/Z isomer, E/Z isomer mixture and/or tautomer thereof; a process for preparing these compounds, their isomers and tautomers and the use of these compounds, their isomers and tautomers; pesticidal compositions whose active compound is selected from these compounds and their tautomers; intermediates for the preparation of the said compounds of the formula (I), methods for the preparation of the compounds of the formula (I), and a method for controlling pests using these compositions.
    • 描述的是式(I)的化合物,其中A-B是-CH-CH-或-CH 2 -CH 2 - 。 n为0或1; R 1是C 1 -C 12烷基,C 3 -C 8烷基,C 3 -C 12烷基,C 3 -C 12烷基,C 3 -C 12烷基, >环烷基或C 2 -C 12 - 烯基; 例如,R 2和R 3是(i)彼此独立地例如-Q,-C(-Y)-Q或-C( - Y)-OQ; 或(ii)与其结合的氮原子一起形成三至七元环,(iii)一起为-C(R 4)R 5 >; R 4和R 5各自独立地为例如-Q,-C(-Y)-Q或-C(-Y)-O-Q; Y为O或S; Q是例如H或未被取代或单取代或未取代的C 1 -C 12烷基; 或者,如果合适的话,E / Z异构体,E / Z异构体混合物和/或其互变异构体; 制备这些化合物,其异构体和互变异构体的方法以及这些化合物,其异构体和互变异构体的用途; 活性化合物选自这些化合物及其互变异构体的杀虫组合物; 用于制备所述式(I)化合物的中间体,式(I)化合物的制备方法和使用这些组合物来控制害虫的方法。