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11. 发明申请

WO2005120644A3 SYSTEM AND METHOD FOR AUTOMATED TITRATION OF CONTINUOUS POSITIVE AIRWAY PRESSURE 审中-公开
标题翻译：连续积极航空压力自动测度系统与方法
公开(公告)号：WO2005120644A3
公开(公告)日：2006-03-23
申请号：PCT/US2005019093
申请日：2005-06-01
申请人： UNIV NEW YORK , NORMAN ROBERT G , RAPOPORT DAVID M
发明人： NORMAN ROBERT G , RAPOPORT DAVID M
IPC分类号： A61M16/00 , A61M16/10 , A62B7/00 , F16K31/02
CPC分类号： A61M16/10 , A61M16/0069 , A61M16/024 , A61M2016/0021 , A61M2016/0039
摘要： Described is a method and system for automated titration of CPAP. The system may include an air pressure supply (22) providing air pressure to a patient's airways and a sensor (23) detecting input data corresponding to a patient's breathing patterns of a plurality of breaths. The system also includes a titration device (26) which receives and analyzes the input data to determine existence of breathing disorder and corresponding characteristics. The titration device generating output data for adjusting the air pressure supplied to the patient as a function of the characteristics of the breathing disorder.
摘要翻译：描述了一种自动滴定CPAP的方法和系统。该系统可以包括向患者的气道提供空气压力的空气压力供应（22）和检测对应于多个呼吸的患者的呼吸模式的输入数据的传感器（23）。该系统还包括滴定装置（26），其接收和分析输入数据以确定呼吸障碍的存在和相应的特征。滴定装置产生输出数据，用于根据呼吸障碍的特征调节供应给患者的气压。

12. 发明申请

WO2005018416A3 POSITIVE AIRWAY PRESSURE SYSTEM AND METHOD FOR TREATMENT OF SLEEPING DISORDER IN PATIENT 审中-公开
标题翻译：积极的空气压力系统和治疗患者睡眠障碍的方法
公开(公告)号：WO2005018416A3
公开(公告)日：2005-08-04
申请号：PCT/US2004023433
申请日：2004-07-21
申请人： UNIV NEW YORK , RAPOPORT DAVID M , NORMAN ROBERT G
发明人： RAPOPORT DAVID M , NORMAN ROBERT G
IPC分类号： A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/0476 , A61B5/08 , A61B5/087 , A61M16/00 , A61M16/06
CPC分类号： A61B5/0816 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/0476 , A61B5/087 , A61B5/4809 , A61B5/4818 , A61M16/0066 , A61M16/0069 , A61M16/024 , A61M16/06 , A61M2016/0021 , A61M2016/0039
摘要： Described are a positive airway pressure system and method for treatment of a sleeping disorder in a patient. The system includes a generator, a sensor and a processing arrangement. The generator supplies airflow and applies a pressure at to an airway of a patient. The sensor measures data corresponding to patient's breathing patterns. The processing arrangement analyzes the breathing patterns to determine whether the breathing patterns are indicative of at least one of the following patient's states: (i) a regular breathing state, (ii) a sleep disorder breathing state,.(iii) a REM sleep state and (iv) a troubled wakefulness state. The processing arrangement adjusts the applied pressure as a function of the patient's state.
摘要翻译：描述了用于治疗患者睡眠障碍的正气道压力系统和方法。该系统包括发电机，传感器和处理装置。发电机提供气流并向患者的气道施加压力。传感器测量对应于患者呼吸模式的数据。处理装置分析呼吸模式以确定呼吸模式是否指示以下患者状态中的至少一个：（i）正常呼吸状态，（ii）睡眠障碍呼吸状态，（iii）REM睡眠状态和（iv）困扰的觉醒状态。处理装置根据病人的状态来调节施加的压力。

13. 发明申请

WO2007041182A3 SYSTEM AND METHOD FOR AUTOMATED TITRATION OF CONTINUOUS POSITIVE AIRWAY PRESSURE USING AN OBSTRUCTION INDEX 审中-公开
标题翻译：使用障碍指数自动滴定连续正压气道压力的系统和方法
公开(公告)号：WO2007041182A3
公开(公告)日：2007-10-11
申请号：PCT/US2006037738
申请日：2006-09-28
申请人： UNIV NEW YORK , AYAPPA INDU A , NORMAN ROBERT G , RAPOPORT DAVID M
发明人： AYAPPA INDU A , NORMAN ROBERT G , RAPOPORT DAVID M
IPC分类号： A61M16/00
CPC分类号： A61M16/0051 , A61M16/0069 , A61M16/024 , A61M16/0431 , A61M16/10 , A61M2016/0021 , A61M2016/0027
摘要： Described is a system including an air pressure supply arrangement, a sensor and a titration device. The air pressure supply arrangement provides air pressure to a patient's airways. The sensor detects input data corresponding to a patient's breathing patterns of a plurality of breaths. The titration device receives and analyzes the input data to determine existence of breathing disorder and corresponding characteristics. The titration device generates output data for adjusting the air pressure supplied to the patient as a function of an index of abnormal respiratory events included in the input data.
摘要翻译：描述了包括气压供应装置，传感器和滴定装置的系统。气压供应装置向患者的气道提供气压。传感器检测对应于患者的多次呼吸的呼吸模式的输入数据。滴定装置接收并分析输入数据以确定呼吸障碍和相应特征的存在。滴定装置根据包含在输入数据中的异常呼吸事件的指标生成输出数据，用于调整提供给患者的气压。

14. 发明申请

WO2012006339A3 SYSTEM AND METHOD FOR DIAGNOSIS AND TREATMENT OF OBSTRUCTIVE SLEEP APNEA 审中-公开
标题翻译：用于诊断和治疗阻塞性睡眠呼吸暂停的系统和方法
公开(公告)号：WO2012006339A3
公开(公告)日：2012-03-29
申请号：PCT/US2011043054
申请日：2011-07-06
申请人： UNIV NEW YORK , RAPOPORT DAVID M , NORMAN ROBERT G , AYAPPA INDU A
发明人： RAPOPORT DAVID M , NORMAN ROBERT G , AYAPPA INDU A
IPC分类号： A61B5/08 , A61B5/091
CPC分类号： A61M16/00 , A61B5/087 , A61M16/0066 , A61M16/0069 , A61M16/024 , A61M2016/0021 , A61M2016/0039
摘要： A system for diagnosis and treatment of breathing disorders includes a flow generator supplying an air flow to an airway of a patient via a flow path, a venting arrangement moveable between (i) a closed position in which the flow path is substantially sealed between the flow generator and the patient's airway and (ii) an open position in which the flow path is open to an ambient atmosphere, a sensor detecting data corresponding to flow through the patient's airway, and a processing arrangement controlling operation of the venting arrangement and the flow generator, wherein, in a diagnostic mode, the processing arrangement maintains the venting arrangement in the open position and in a therapeutic mode, the processing arrangement maintains the venting arrangement in the closed position and controls the flow generator to supply to the patient's airway via the flow path a calculated therapeutic pressure.
摘要翻译：一种用于呼吸障碍的诊断和治疗的系统包括流量发生器，该流量发生器经由流动路径向患者的气道供应气流，所述通气装置可在（i）关闭位置和关闭位置之间移动，在所述关闭位置中，流动路径基本上被密封在流动发生器和患者的气道以及（ii）打开位置，其中流动路径对于环境大气开放，传感器检测与通过患者气道的流动相对应的数据，以及处理装置，其控制通气装置和流动发生器的操作，其中在诊断模式中，所述处理装置保持所述通气装置处于所述打开位置并且处于治疗模式中，所述处理装置将所述通气装置保持在所述关闭位置并且控制所述气流发生器以经由所述气流向所述患者的气道供应计算治疗压力。

15. 发明申请

WO2010124191A3 SYSTEM AND METHOD FOR CIRCUITS TO ALLOW CPAP TO PROVIDE ZERO PRESSURE 审中-公开
标题翻译：电路允许CPAP提供零压力的系统和方法
公开(公告)号：WO2010124191A3
公开(公告)日：2011-02-03
申请号：PCT/US2010032211
申请日：2010-04-23
申请人： UNIV NEW YORK , RAPOPORT DAVID M
发明人： RAPOPORT DAVID M
IPC分类号： A61M16/00 , A61M16/20
CPC分类号： A61M16/0069 , A61M1/00 , A61M16/0003 , A61M16/0066 , A61M16/06 , A61M16/0875 , A61M16/10 , A61M16/20 , A61M16/201 , A61M16/202 , A61M2016/0027 , A61M2016/003 , A61M2202/0225 , A61M2205/3334 , A61M2202/0085
摘要： A system comprises a respiratory delivery arrangement adapted to cover at least one respiratory orifice of a patient. The system also comprises a first conduit having a first end and a second end, the second end connected to the respiratory delivery arrangement. A positive pressure is provided to the respiratory orifice via the first conduit and a second conduit having a third end and a fourth end, the fourth end connected to the respiratory delivery arrangement. An exhaled gas is extracted from the respiratory orifice by one or both of a valve configured to redirect flow through the respiratory delivery arrangement and a venturi opening.
摘要翻译：系统包括适于覆盖患者的至少一个呼吸孔的呼吸递送装置。该系统还包括具有第一端和第二端的第一导管，第二端连接到呼吸输送装置。经由第一导管向呼吸孔提供正压力，第二导管具有第三端和第四端，第四端连接到呼吸输送装置。呼吸气体由构造成引导通过呼吸输送装置的流动和文丘里开口的阀中的一个或两个从呼吸孔抽取。

16. 发明申请

WO2007040988A3 SYSTEM AND METHOD FOR DIAGNOSIS AND TREATMENT OF A BREATHING PATTERN OF A PATIENT 审中-公开
标题翻译：诊断和治疗患者呼吸模式的系统和方法
公开(公告)号：WO2007040988A3
公开(公告)日：2007-06-21
申请号：PCT/US2006036594
申请日：2006-09-20
申请人： UNIV NEW YORK , RAPOPORT DAVID M , NORMAN ROBERT G
发明人： RAPOPORT DAVID M , NORMAN ROBERT G
IPC分类号： A61M16/00 , A61B5/08
CPC分类号： A61M16/0057 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/0476 , A61B5/0816 , A61B5/087 , A61B5/4809 , A61B5/4812 , A61B5/4818 , A61B5/7267 , A61M16/00 , A61M16/0051 , A61M16/0066 , A61M16/0069 , A61M16/026 , A61M16/06 , A61M2016/0021 , A61M2016/0039 , A61M2205/3344 , A61M2230/005 , A61M2230/40
摘要： Described is a system including a sensor and a processing arrangement. The sensor measures data corresponding to a patient's breathing patterns. The processing arrangement analyzes the breathing patterns to determine whether the breathing patterns are indicative of a REM sleep state. In another embodiment, the processing arrangement analyzes the breathing patterns to determine whether the breathing patterns are indicative of one of the following states: (i) a wake state and (ii) a sleep state. In another embodiment, a neural network analyzes the data to determine whether the breathing patterns are indicative of one of the following states: (i) a REM sleep state, (ii) a wake state and (iii) a sleep state. In another embodiment, the processing arrangement analyzes the data to determine whether the breathing pattern is indicative of an arousal.
摘要翻译：描述了包括传感器和处理装置的系统。传感器测量对应于患者呼吸模式的数据。处理装置分析呼吸模式以确定呼吸模式是否指示REM睡眠状态。在另一个实施例中，处理装置分析呼吸模式以确定呼吸模式是否指示以下状态之一：（i）唤醒状态和（ii）睡眠状态。在另一个实施例中，神经网络分析数据以确定呼吸模式是否指示以下状态之一：（i）REM睡眠状态，（ii）唤醒状态和（iii）睡眠状态。在另一个实施例中，处理装置分析数据以确定呼吸模式是否指示唤醒。

17. 发明申请

WO2005000805A3 SYSTEM AND METHOD FOR IMPROVED TREATMENT OF SLEEPING DISORDERS USING THERAPEUTIC POSITIVE AIRWAY PRESSURE 审中-公开
标题翻译：使用治疗性积极空气压力改善睡眠障碍治疗的系统和方法
公开(公告)号：WO2005000805A3
公开(公告)日：2006-02-23
申请号：PCT/US2004017703
申请日：2004-06-04
申请人： UNIV NEW YORK , RAPOPORT DAVID M
发明人： RAPOPORT DAVID M
IPC分类号： A61M16/00 , A61M16/06 , A62B7/00 , F16K31/02
CPC分类号： A61M16/024 , A61M16/06 , A61M2016/0021 , A61M2016/0039
摘要： Described is a method and system providing therapeutic positive airway pressure to a particular area of patient's airways. The system may include a flow generator and a processing arrangement. The flow generator supplies an airflow to an airway of the patient. The processing arrangement is connected to the flow generator to control a supply pressure at which the airflow is generated by the flow generator. The processing arrangement continuously adjusts the supply pressure to maintain a pressure in a predetermined portion of the patent's airway substantially constant. The predetermined portion of the patient's airway includes a collapsible portion of an upper airway of the patient. The processing arrangement also controls the supply pressure to maintain the pressure in the collapsible portion of the patient's airway at a value at least as great as a tissue pressure below which the collapsible portion collapses.
摘要翻译：描述了向患者气道的特定区域提供治疗性气道正压的方法和系统。该系统可以包括流量发生器和处理装置。流量发生器向患者的气道提供气流。处理装置连接到流量发生器以控制流量发生器产生气流的供应压力。处理装置连续地调节供应压力以保持专利气道的预定部分中的压力基本上恒定。患者气道的预定部分包括患者的上呼吸道的可折叠部分。处理装置还控制供应压力以将患者气道的可收缩部分中的压力保持在至少与可压缩部分折叠的组织压力以下的值。

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