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11. 发明授权

US08556797B2 Magnetic implants for treating obstructive sleep apnea and methods therefor 有权
标题翻译：用于治疗阻塞性睡眠呼吸暂停的磁性植入物及其方法
公开(公告)号：US08556797B2
公开(公告)日：2013-10-15
申请号：US12183955
申请日：2008-07-31
申请人： Kevin Weadock , Robert A. Rousseau
发明人： Kevin Weadock , Robert A. Rousseau
IPC分类号： A61F2/00
CPC分类号： A61F5/566
摘要： A magnetic implant for treating sleep disorders includes a first anchor, a first magnet coupled to the first anchor, a tongue anchor, a second magnet coupled to the tongue anchor, and a support for aligning the first and second magnets so that a repelling force is generated between the magnets for urging the second magnet away from the first magnet. In one embodiment, the support aligns a magnetic pole of the first magnet with a repelling magnetic pole of the second magnet, guides movement of the first and second magnets relative to one another, and maintains the first magnet at a fixed distance from the first anchor. In one embodiment, the repelling force urges the second magnet toward the first anchor. The first anchor may be connected to bone or soft tissue.
摘要翻译：一种用于治疗睡眠障碍的磁性植入物包括第一锚固件，联接到第一锚固件的第一磁体，舌锚固件，联接到舌锚固件的第二磁体和用于使第一和第二磁体对准的支撑件，使得排斥力为在磁体之间产生用于将第二磁体推离第一磁体的位置。在一个实施例中，支撑件使第一磁体的磁极与第二磁体的排斥磁极对准，引导第一和第二磁体相对于彼此的运动，并且将第一磁体保持在距离第一磁体的固定距离。在一个实施例中，排斥力将第二磁体推向第一锚。第一锚可以连接到骨或软组织。

12. 发明授权

US08307831B2 Implant systems and methods for treating obstructive sleep apnea 有权
标题翻译：植入系统和治疗阻塞性睡眠呼吸暂停的方法
公开(公告)号：US08307831B2
公开(公告)日：2012-11-13
申请号：US12404377
申请日：2009-03-16
申请人： Robert A. Rousseau
发明人： Robert A. Rousseau
IPC分类号： A61F5/56
CPC分类号： A61F5/566 , A61F5/56
摘要： A system for treating obstructive sleep apnea includes a body implantable in a soft palate, and a fastening element at a proximal end of the body for connecting the body with a hard palate. In one embodiment, the body is curved and has a convex top surface and a concave bottom surface. The curved body is adapted to support and/or change the shape of the soft palate for minimizing the likelihood of airway obstructions during sleep. The fastening element, secureable to the hard palate, includes at least one barb adapted to engage the hard palate for anchoring the body to the hard palate. In one embodiment, the body has a surface adapted to promote tissue in-growth. The implant body may be made of materials including nitinol, stainless steel, biocompatible polymers, temperature-sensitive materials, and shape memory materials.
摘要翻译：用于治疗阻塞性睡眠呼吸暂停的系统包括可植入软腭的身体和在身体的近端处的紧固元件，用于将身体与硬腭连接。在一个实施例中，主体是弯曲的并且具有凸顶表面和凹底面。弯曲的身体适于支撑和/或改变软腭的形状，以最小化睡眠期间呼吸道障碍的可能性。可固定到硬腭的紧固元件包括适于接合硬腭的至少一个倒钩，用于将身体固定到硬腭上。在一个实施方案中，身体具有适于促进组织生长的表面。植入体可以由包括镍钛诺，不锈钢，生物相容性聚合物，温度敏感材料和形状记忆材料的材料制成。

13. 发明申请

US20110100377A1 TONGUE SUSPENSION SYSTEM WITH HYOID-EXTENDER FOR TREATING OBSTRUCTIVE SLEEP APNEA 有权
标题翻译：用于治疗阻塞性睡眠障碍的超声剂延迟系统
公开(公告)号：US20110100377A1
公开(公告)日：2011-05-05
申请号：US12608168
申请日：2009-10-29
申请人： Kevin S. Weadock , Robert A. Rousseau , David C. Lindh, SR.
发明人： Kevin S. Weadock , Robert A. Rousseau , David C. Lindh, SR.
IPC分类号： A61F5/56
CPC分类号： A61F5/566
摘要： A system for treating obstructive sleep apnea includes a first element implantable in a tongue and a second element implantable between muscle planes of an inframandibular region. The second element has a first end coupled with the first element and a second end coupled with a hyoid bone for preventing the base of the tongue from collapsing against an opposing pharyngeal wall during sleep. The first and second implantable elements have outer surfaces that are substantially impermeable to tissue in-growth to allow for post-surgical adjustment or removal, if necessary. The first implantable element is elongated and includes a first end, a second end, and a center section located between the first and second ends. The center section is implantable in the tongue, and the first and second ends of the first implantable element are advanceable beneath the tongue for being coupled with the anterior end of the second implantable element.
摘要翻译：用于治疗阻塞性睡眠呼吸暂停的系统包括可植入舌头的第一元件和可植入在下颌下区域的肌肉平面之间的第二元件。第二元件具有与第一元件相结合的第一端和与舌骨相连的第二端，用于防止舌头的基部在睡眠期间塌陷在相对的咽壁上。第一和第二可植入元件具有外表面，其对组织生长进行基本上是不可渗透的，以便在需要时进行手术后调整或移除。第一可植入元件是细长的并且包括第一端部，第二端部和位于第一端部和第二端部之间的中心部分。中心部分可植入舌部，并且第一可植入元件的第一和第二端可在舌下方前进，以与第二可植入元件的前端相连。

14. 发明申请

US20100312358A1 Implantable Repair Device 有权
标题翻译：植入式修复装置
公开(公告)号：US20100312358A1
公开(公告)日：2010-12-09
申请号：US12858827
申请日：2010-08-18
申请人： Robert A. Rousseau , David C. Lindh, SR. , John R. Jacobs , Ilya S. Koyfman , Gaoyuan Gavin Chen , Donald G. Hill
发明人： Robert A. Rousseau , David C. Lindh, SR. , John R. Jacobs , Ilya S. Koyfman , Gaoyuan Gavin Chen , Donald G. Hill
IPC分类号： A61F2/02
CPC分类号： A61F2/02 , A61F2/0063 , A61F2002/0068 , A61F2210/0004
摘要： An implantable prosthesis for repairing or reinforcing a tissue or muscle wall defect including a first composite structure including at least one layer of a non-absorbable material, wherein the first composite structure has a central portion sized and shaped to cover at least a portion of the tissue or muscle wall defect, and has an outer periphery. The prosthesis further includes a second structure having a reinforced central region and an outer peripheral edge, a reinforcing element positioned between the first and second structures, and having an outer periphery and a stiffness greater than that of the first and second structures, and at least one pulling element coupled to the reinforced central region of the second structure. The second structure is coupled to the first structure substantially only at their respective peripheries.
摘要翻译：一种用于修复或加强组织或肌肉壁缺损的可植入假体，其包括包括至少一层不可吸收材料的第一复合结构，其中所述第一复合结构具有尺寸和形状以覆盖所述第一复合结构的至少一部分的中心部分组织或肌肉壁缺损，并具有外周。所述假体还包括具有加强的中心区域和外周边缘的第二结构，位于所述第一和第二结构之间的加强元件，并且具有大于所述第一和第二结构的外周边和刚度的至少一个牵引元件联接到第二结构的加强中心区域。第二结构基本上仅在它们各自的周边耦合到第一结构。

15. 发明申请

US20100080791A1 Composition and Method For Treating Tissue Defects 审中-公开
标题翻译：用于治疗组织缺损的组合物和方法
公开(公告)号：US20100080791A1
公开(公告)日：2010-04-01
申请号：US12238991
申请日：2008-09-26
申请人： Robert A. Rousseau , Kevin S. Weadock , John R. Jacobs
发明人： Robert A. Rousseau , Kevin S. Weadock , John R. Jacobs
IPC分类号： A61K38/48 , A61K38/36 , A61P17/00 , A61Q19/00
CPC分类号： A61L27/48 , A61L27/446 , A61L27/50
摘要： The present invention provides a composition and method for treating tissue defects. The composition includes thrombin and fibrinogen, or sodium alginate and calcium chloride, and also a surfactant, and non-resorbable polymer microparticles dispersed within the composition.
摘要翻译：本发明提供了治疗组织缺陷的组合物和方法。组合物包括凝血酶和纤维蛋白原，藻酸钠和氯化钙，以及分散在组合物内的表面活性剂和不可再吸收的聚合物微粒。

16. 发明授权

US09173766B2 Systems and methods to treat upper pharyngeal airway of obstructive sleep apnea patients 有权
标题翻译：阻塞性睡眠呼吸暂停患者上咽气道治疗的系统和方法
公开(公告)号：US09173766B2
公开(公告)日：2015-11-03
申请号：US13486293
申请日：2012-06-01
申请人： An-Min Jason Sung , Robert A. Rousseau , David C. Lindh, Sr.
发明人： An-Min Jason Sung , Robert A. Rousseau , David C. Lindh, Sr.
IPC分类号： A61F5/56
CPC分类号： A61F5/566
摘要： Obstructive Sleep Apnea (OSA) may be caused by a collapse of the pharyngeal wall as a result of increasing negative airway pressure. This invention is directed to systems and methods to resist collapse of the pharyngeal wall by minimally invasive upper pharyngeal airway surgery.
摘要翻译：阻塞性睡眠呼吸暂停（OSA）可能是由于气道压力增加导致咽壁塌陷引起的。本发明涉及通过微创上咽气道手术抵抗咽壁塌陷的系统和方法。

17. 发明授权

US08973582B2 Tongue suspension device and method 有权
标题翻译：舌悬挂装置及方法
公开(公告)号：US08973582B2
公开(公告)日：2015-03-10
申请号：US13307482
申请日：2011-11-30
申请人： Robert A. Rousseau
发明人： Robert A. Rousseau
IPC分类号： A61F5/56 , A61C5/14
CPC分类号： A61F5/566
摘要： An implantable tissue suspension device and its method for use. The device includes first and second filamentary elements bonded together only at a central connection region such that first and second leading and trailing legs of the respective first and second filamentary elements extend outwardly from the central connection region. The method includes implanting the device such that the central connection region extends laterally across a patient's tongue and the first and second leading and trailing legs of the first and second filamentary elements extend through the tongue such that ends thereof are positioned external to the genioglossus muscle.
摘要翻译：一种可植入组织悬浮装置及其使用方法。该装置包括仅在中心连接区域处结合在一起的第一和第二丝状元件，使得相应的第一和第二丝状元件的第一和第二前后腿从中心连接区域向外延伸。该方法包括植入装置使得中心连接区域横向延伸穿过患者的舌部，并且第一和第二丝状元件的第一和第二前导腿和后腿延伸穿过舌部，使得其端部位于颏舌肌的外部。

18. 发明授权

US08561616B2 Methods and devices for the indirect displacement of the hyoid bone for treating obstructive sleep apnea 有权
标题翻译：舌骨间接移位用于治疗阻塞性睡眠呼吸暂停的方法和装置
公开(公告)号：US08561616B2
公开(公告)日：2013-10-22
申请号：US12257563
申请日：2008-10-24
申请人： Robert A. Rousseau , Kevin S. Weadock
发明人： Robert A. Rousseau , Kevin S. Weadock
IPC分类号： A61F13/00 , A61F5/56 , A61C5/14 , A61B19/00
CPC分类号： A61F5/566
摘要： An implant for treating obstructive sleep apnea includes an elongated body having a central region, a first end, and a second end opposite the first end. The central region of the elongated body engages inframandibular musculature that extends between a mandible and a hyoid bone. The first and second ends of the elongated body are optionally anchored to the mandible. The elongated body is under tension for urging the inframandibular musculature in an inferior direction, which, in turn, pulls the hyoid bone anteriorly for minimizing the likelihood of occurrence of obstructive sleep apnea episodes.
摘要翻译：用于治疗阻塞性睡眠呼吸暂停的植入物包括具有中心区域，第一端和与第一端相对的第二端的细长体。细长体的中心区域接合在下颌骨和舌骨之间延伸的下颌骨肌肉组织。细长体的第一和第二端可选地被锚定到下颌骨。细长的身体处于紧张状态，用于沿较低的方向推动下颌骨肌肉组织，这又反过来拉动舌骨前方以最小化发生阻塞性睡眠呼吸暂停发作的可能性。

19. 发明申请

US20130174857A1 METHODS AND DEVICES FOR TREATMENT OF OBSTRUCTIVE SLEEP APNEA 有权
标题翻译：用于治疗阻塞性睡眠障碍的方法和装置
公开(公告)号：US20130174857A1
公开(公告)日：2013-07-11
申请号：US13784077
申请日：2013-03-04
申请人： Robert A. Rousseau , Kevin S. Weadock
发明人： Robert A. Rousseau , Kevin S. Weadock
IPC分类号： A61F5/56
CPC分类号： A61F5/56 , A61F5/566
摘要： A pharyngeal retractor device and implantation methods are provided for use in the treatment of obstructive sleep apnea. The device includes a retracting element and a tissue engaging element that promotes tissue ingrowth around or onto the retracting element. The device is implanted in tissue space beneath the pharyngeal wall to alter the shape of the wall. The device may be implanted through the oral cavity alone or by using a trocar or a hand-held delivery system to deliver the device through the pharyngeal wall. Alternatively, the device may be implanted using an open, direct visualization approach from the side of a patient's neck.
摘要翻译：提供咽收缩器装置和植入方法用于治疗阻塞性睡眠呼吸暂停。该装置包括回缩元件和组织接合元件，其促进组织向内生长在收缩元件周围或上。该装置植入咽壁下方的组织空间以改变壁的形状。该装置可以单独地通过口腔植入，或者通过使用套管针或手持递送系统将装置输送通过咽壁。或者，可以使用来自患者颈部侧面的开放的直接可视化方法来植入该装置。

20. 发明申请

US20130139828A1 MEDICAL INSERTION DEVICE AND METHOD OF USE 有权
标题翻译：医疗插入装置及其使用方法
公开(公告)号：US20130139828A1
公开(公告)日：2013-06-06
申请号：US13309751
申请日：2011-12-02
申请人： Robert A. Rousseau , David C. Lindh, SR.
发明人： Robert A. Rousseau , David C. Lindh, SR.
IPC分类号： A61F5/56 , A61B17/28
CPC分类号： A61B17/0483 , A61B17/0469 , A61B17/0485 , A61B17/06109 , A61B17/0642 , A61B17/0682 , A61B2017/00455 , A61B2017/06009 , A61B2017/06042 , A61B2017/06052 , A61B2017/0641 , A61B2090/0807 , A61F5/566 , F04C2270/0421
摘要： An insertion device and method of use for treating obstructive sleep apnea. The device includes an outer tubular element with a tissue penetrating end and a side opening, an inner tubular element positioned partially within the outer member and movable longitudinally relative to it, a grasping device fixedly coupled to the inner element, and a central shaft extending through the inner tubular element and movable longitudinally relative to the inner and outer tubular elements. The central shaft is slidably coupled with the grasping device. The inner tubular element is further movable between a retracted position wherein the grasping device is positioned entirely within the outer tubular element, and an extended position wherein it extends outwardly therefrom through the side opening. In the extended position, the grasping device is adapted to grasp a filamentary element positioned external of the outer tubular element and in proximity thereto.
摘要翻译：一种用于治疗阻塞性睡眠呼吸暂停的插入装置和方法。该装置包括具有组织穿透端和侧开口的外部管状元件，内部管状元件，其部分地位于外部构件内并相对于其纵向移动，固定地联接到内部元件的抓握装置和延伸穿过的中心轴内部管状元件并且相对于内部和外部管状元件纵向移动。中心轴与抓握装置可滑动地联接。内部管状元件还可以在缩回位置之间移动，其中抓握装置完全位于外部管状元件内，并且延伸位置，其中通过侧开口向外延伸。在延伸位置，抓持装置适于抓住位于外部管状元件外部并且靠近其的丝状元件。

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