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11. 发明授权

US08104644B2 One-way valve and apparatus and method of using the valve 有权
标题翻译：单向阀及其使用方法及阀门
公开(公告)号：US08104644B2
公开(公告)日：2012-01-31
申请号：US12901422
申请日：2010-10-08
申请人： Daniel Py , Julian V. Chan , Benoit Adamo , Nathaniel Houle
发明人： Daniel Py , Julian V. Chan , Benoit Adamo , Nathaniel Houle
IPC分类号： B65D37/00
CPC分类号： B67D1/108 , B05B11/00444 , B65B39/004 , B65D51/002 , B65D51/1616 , B67D1/0004 , B67D1/0007 , B67D1/0009 , B67D1/0082 , B67D1/0801 , B67D1/10 , B67D1/1279 , B67D3/0067 , B67D3/04 , B67D2001/0827 , F04B53/1037
摘要： A flexible pouch and valve assembly is provided for aseptically storing a substance, dispensing multiple portions of the stored substance therefrom, and maintaining substance remaining in the pouch in an aseptic condition sealed with respect to ambient atmosphere. The flexible pouch and valve assembly are receivable within a relatively rigid housing, and are adapted to cooperate with a pump for pumping discrete portions of substance from the pouch and through the one-way valve to dispense the substance therefrom. The assembly comprises a flexible pouch defining therein a variable-volume storage chamber sealed with respect to the ambient atmosphere for aseptically storing therein multiple portions of the substance. A one-way valve of the assembly includes a valve body defining an axially-extending valve seat and at least one flow aperture extending through the valve body and/or the valve seat.
摘要翻译：提供了一种柔性袋和阀组件，用于无菌存储物质，从其中分配多部分储存物质，并将残留在袋中的物质保持在相对于环境大气密封的无菌状态。柔性袋和阀组件可接收在相对刚性的壳体内，并且适于与泵协作，用于泵送物质的离散部分并且通过单向阀从其分配物质。组件包括柔性袋，其中限定有相对于环境大气密封的可变容积存储室，用于将物质的多个部分无菌存储。组件的单向阀包括限定轴向延伸的阀座的阀体和延伸穿过阀体和/或阀座的至少一个流动孔。

12. 发明授权

US07278553B2 One-way valve and apparatus using the valve 有权
标题翻译：单向阀和使用阀门的装置
公开(公告)号：US07278553B2
公开(公告)日：2007-10-09
申请号：US11295274
申请日：2005-12-05
申请人： Daniel Py , Julian V. Chan , Benoit Adamo , Nathaniel Houle
发明人： Daniel Py , Julian V. Chan , Benoit Adamo , Nathaniel Houle
IPC分类号： B65D37/00
CPC分类号： B67D1/0004 , B65B39/004 , B67D1/0007 , B67D1/0009 , B67D1/0082 , B67D1/10 , B67D1/108 , B67D1/1279 , B67D3/04 , B67D2001/0827 , F04B43/1238 , F04B53/1037 , Y10T137/7761
摘要： An apparatus has a valve body defining a first passageway, a valve seat, and a flow aperture extending through the valve body and coupled in fluid communication with the first passageway. An elastic valve cover includes a valve portion overlying the valve seat, forming an interference fit with the valve seat, and defining an axially-extending valve opening therebetween. The valve portion is movable between a normally closed position with the valve portion engaging the valve seat, and an open position with at least a segment of the valve portion spaced away from the valve seat to allow the passage of fluid from the flow aperture through the valve opening. A hermetically sealed variable-volume storage chamber is connectible in fluid communication with the one-way valve assembly. A pump is coupled between the variable-volume storage chamber and the one-way valve assembly to dispense discrete portions of fluid through the valve assembly.
摘要翻译：一种装置具有限定第一通道，阀座和延伸穿过阀体并与第一通道流体连通地联接的流动孔的阀体。弹性阀盖包括覆盖在阀座上的阀部分，与阀座形成过盈配合，并在其间限定一个轴向延伸的阀开口。阀部分可以在与阀座接合的阀部分的常闭位置和打开位置之间移动，打开位置具有与阀座间隔开的阀部分的至少一段，以允许流体从流动孔通过通过阀门开启。密封的可变容积的储存室可与单向阀组件流体连通地连接。泵连接在可变体积存储室和单向阀组件之间，以通过阀组件分配流体的离散部分。

13. 发明申请

US20140246462A1 ONE-WAY VALVE AND APPARATUS AND METHOD OF USING THE VALVE 有权
标题翻译：单向阀和装置以及使用阀的方法
公开(公告)号：US20140246462A1
公开(公告)日：2014-09-04
申请号：US14101981
申请日：2013-12-10
申请人： Daniel Py , Julian V. Chan , Benoit Adamo , Nathaniel Houle
发明人： Daniel Py , Julian V. Chan , Benoit Adamo , Nathaniel Houle
IPC分类号： B65D37/00
CPC分类号： B67D1/108 , B05B11/00444 , B65B39/004 , B65D51/002 , B65D51/1616 , B67D1/0004 , B67D1/0007 , B67D1/0009 , B67D1/0082 , B67D1/0801 , B67D1/10 , B67D1/1279 , B67D3/0067 , B67D3/04 , B67D2001/0827 , F04B53/1037
摘要： A flexible pouch and valve assembly is provided for aseptically storing a substance, dispensing multiple portions of the stored substance therefrom, and maintaining substance remaining in the pouch in an aseptic condition sealed with respect to ambient atmosphere. The flexible pouch and valve assembly are receivable within a relatively rigid housing, and are adapted to cooperate with a pump for pumping discrete portions of substance from the pouch and through the one-way valve to dispense the substance therefrom. The assembly comprises a flexible pouch defining therein a variable-volume storage chamber sealed with respect to the ambient atmosphere for aseptically storing therein multiple portions of the substance. A one-way valve of the assembly includes a valve body defining an axially-extending valve seat and at least one flow aperture extending through the valve body and/or the valve seat.
摘要翻译：提供了一种柔性袋和阀组件，用于无菌存储物质，从其中分配多部分储存物质，并将残留在袋中的物质保持在相对于环境大气密封的无菌状态。柔性袋和阀组件可接收在相对刚性的壳体内，并且适于与泵协作，用于泵送物质的离散部分并且通过单向阀从其分配物质。组件包括柔性袋，其中限定有相对于环境大气密封的可变容积存储室，用于将物质的多个部分无菌存储。组件的单向阀包括限定轴向延伸的阀座的阀体和延伸穿过阀体和/或阀座的至少一个流动孔。

14. 发明授权

US08602259B2 One-way valve and apparatus and method of using the valve 有权
公开(公告)号：US08602259B2
公开(公告)日：2013-12-10
申请号：US13362532
申请日：2012-01-31
申请人： Daniel Py , Julian V. Chan , Benoit Adamo , Nathaniel Houle
发明人： Daniel Py , Julian V. Chan , Benoit Adamo , Nathaniel Houle
IPC分类号： B67D7/14
CPC分类号： B67D1/108 , B05B11/00444 , B65B39/004 , B65D51/002 , B65D51/1616 , B67D1/0004 , B67D1/0007 , B67D1/0009 , B67D1/0082 , B67D1/0801 , B67D1/10 , B67D1/1279 , B67D3/0067 , B67D3/04 , B67D2001/0827 , F04B53/1037
摘要： A flexible pouch and valve assembly is provided for aseptically storing a substance, dispensing multiple portions of the stored substance therefrom, and maintaining substance remaining in the pouch in an aseptic condition sealed with respect to ambient atmosphere. The flexible pouch and valve assembly are receivable within a relatively rigid housing, and are adapted to cooperate with a pump for pumping discrete portions of substance from the pouch and through the one-way valve to dispense the substance therefrom. The assembly comprises a flexible pouch defining therein a variable-volume storage chamber sealed with respect to the ambient atmosphere for aseptically storing therein multiple portions of the substance. A one-way valve of the assembly includes a valve body defining an axially-extending valve seat and at least one flow aperture extending through the valve body and/or the valve seat.

15. 发明授权

US08181431B2 Sterile de-molding apparatus and method 有权
标题翻译：无菌脱模装置及方法
公开(公告)号：US08181431B2
公开(公告)日：2012-05-22
申请号：US13012074
申请日：2011-01-24
申请人： Daniel Py , Benoit Adamo , John Guthy , Nathaniel Houle , M. Jeffrey Willey
发明人： Daniel Py , Benoit Adamo , John Guthy , Nathaniel Houle , M. Jeffrey Willey
IPC分类号： B65B3/02 , B65B5/02
CPC分类号： B65B3/022
摘要： Apparatus for molding and filling a device having a body defining an opening in communication with an interior chamber for receiving a substance therein, and a closure including a penetrable and resealable portion for sealing the opening and substance received in the device. A mold includes within the aseptic chamber plural mold cavities shaped to form the closure and body, and substantially sterile surfaces extending about and contiguous to the peripheries of the mold cavities. An assembly device including end-of-arm tooling having an engaging portion engageable with each of the body and closure is movable relative to the mold to engage and de-mold the substantially sterile closures and bodies from the mold cavities. Flexible barriers are coupled to the mold and the tool to substantially prevent the passage of contaminants from the molding machine and tool therethrough.
摘要翻译：用于模制和填充具有本体的装置的装置，该主体限定与用于在其中容纳物质的内部腔室连通的开口;以及封闭件，包括用于密封容纳在装置中的开口和物质的可穿透和可重新密封的部分。模具包括在无菌室内的多个模具腔，其形状形成封闭件和主体，以及基本上无菌的表面，其围绕并邻近模具腔的周边延伸。包括端臂工具的组装装置具有可与主体和闭合件中的每一个接合的接合部分，其可相对于模具移动以将基本无菌的闭合件和主体与模腔接合和脱模。柔性屏障耦合到模具和工具，以基本上防止污染物从模制机器和工具通过。

16. 发明授权

US08071009B2 Sterile de-molding apparatus and method 有权
标题翻译：无菌脱模装置及方法
公开(公告)号：US08071009B2
公开(公告)日：2011-12-06
申请号：US11582291
申请日：2006-10-17
申请人： Daniel Py , Benoit Adamo , John Guthy , Nathaniel Houle , Giovanni Rodriguez
发明人： Daniel Py , Benoit Adamo , John Guthy , Nathaniel Houle , Giovanni Rodriguez
IPC分类号： B29C45/04
CPC分类号： B29C45/1701 , B29C37/0007 , B29C45/006 , B29C45/1753 , B29C45/40 , B29C45/42 , B29C2045/1797 , B29C2791/005
摘要： An apparatus and method are provided for molding sterile parts. The apparatus has a first mold portion and a second mold portion. At least one of the first and second mold portions defines a mold cavity configured to receive a molten plastic and form therefrom at least one molded part At least one of the first and second mold portions is movable relative to the other between (i) a closed position for sealing the mold cavity or cavities and molding at least one part therein, and (ii) an open position defining a fluid passageway between the first and second mold portions and permitting the passage of a fluid sterilant therein. A fluid source that contains or otherwise generates a fluid sterilant, such as vaporized hydrogen peroxide, is connectable in fluid communication with the fluid passageway for introducing the sterilant into the fluid passageway with at least one of the first and second mold portions in the open position, and in turn contacting with the sterilant the surfaces of the first and second mold portions forming the fluid passageway and located adjacent to the at least one mold cavity, but not contacting an interior surface of a molded part within the mold cavity, to sterilize the exposed mold surfaces and thereby prevent contamination of the molded part.
摘要翻译：提供了用于模制无菌部件的装置和方法。该装置具有第一模具部分和第二模具部分。第一模具部分和第二模具部分中的至少一个限定了模腔，其被配置为容纳熔融塑料并从其形成至少一个模制部件。第一模具部分和第二模具部分中的至少一个可相对于彼此移动，用于密封模腔或空腔并在其中模制至少一个部件的位置，以及（ii）限定第一和第二模具部分之间的流体通道并允许其中的流体灭菌剂通过的打开位置。包含或以其它方式产生流体灭菌剂的流体源例如蒸发的过氧化氢可连接到流体通道，用于将灭菌剂引入流体通道，其中第一和第二模具部分中的至少一个处于打开位置并且又与灭菌剂接触形成第一和第二模具部分的表面，形成流体通道并且位于与至少一个模具腔相邻但不与模具腔内的模制部件的内表面接触，以消毒暴露的模具表面，从而防止模制部件的污染。

17. 发明申请

US20110113729A1 Sterile De-Molding Apparatus and Method 有权
标题翻译：无菌脱模装置及方法
公开(公告)号：US20110113729A1
公开(公告)日：2011-05-19
申请号：US13012074
申请日：2011-01-24
申请人： Daniel Py , Benoit Adamo , John Guthy , Nathaniel Houle , M. Jeffrey Willey
发明人： Daniel Py , Benoit Adamo , John Guthy , Nathaniel Houle , M. Jeffrey Willey
IPC分类号： B65B55/02 , B65B47/00 , B65B5/02
CPC分类号： B65B3/022
摘要： Apparatus for molding and filling a device having a body defining an opening in communication with an interior chamber for receiving a substance therein, and a closure including a penetrable and resealable portion for sealing the opening and substance received in the device. A mold includes within the aseptic chamber plural mold cavities shaped to form the closure and body, and substantially sterile surfaces extending about and contiguous to the peripheries of the mold cavities. An assembly device including end-of-arm tooling having an engaging portion engageable with each of the body and closure is movable relative to the mold to engage and de-mold the substantially sterile closures and bodies from the mold cavities. Flexible barriers are coupled to the mold and the tool to substantially prevent the passage of contaminants from the molding machine and tool therethrough.
摘要翻译：用于模制和填充具有本体的装置的装置，该主体限定与用于在其中容纳物质的内部腔室连通的开口;以及封闭件，包括用于密封容纳在装置中的开口和物质的可穿透和可重新密封的部分。模具包括在无菌室内的多个模具腔，其形状形成封闭件和主体，以及基本上无菌的表面，其围绕并邻近模具腔的周边延伸。包括端臂工具的组装装置具有可与主体和闭合件中的每一个接合的接合部分，其可相对于模具移动以将基本无菌的闭合件和主体与模腔接合和脱模。柔性屏障耦合到模具和工具，以基本上防止污染物从模制机器和工具通过。

18. 发明申请

US20090145089A1 STERILE DE-MOLDING APPARATUS AND METHOD 有权
标题翻译： STERILE脱模装置和方法
公开(公告)号：US20090145089A1
公开(公告)日：2009-06-11
申请号：US12371601
申请日：2009-02-14
申请人： Daniel Py , Benoit Adamo , John Guthy , Nathaniel Houle , M. Jeffrey Willey
发明人： Daniel Py , Benoit Adamo , John Guthy , Nathaniel Houle , M. Jeffrey Willey
IPC分类号： B65B3/02 , B65B5/02 , B65B55/18 , B65B55/10
CPC分类号： B65B3/022
摘要： Apparatus for molding and filling a device having a body defining an opening in communication with an interior chamber for receiving a substance therein, and a closure including a penetrable and resealable portion for sealing the opening and substance received in the device. A mold includes within the aseptic chamber plural mold cavities shaped to form the closure and body, and substantially sterile surfaces extending about and contiguous to the peripheries of the mold cavities. An assembly device including end-of-arm tooling having an engaging portion engageable with each of the body and closure is movable relative to the mold to engage and de-mold the substantially sterile closures and bodies from the mold cavities. Flexible barriers are coupled to the mold and the tool to substantially prevent the passage of contaminants from the molding machine and tool therethrough.
摘要翻译：用于模制和填充具有本体的装置的装置，该主体限定与用于在其中容纳物质的内部腔室连通的开口;以及封闭件，包括用于密封容纳在装置中的开口和物质的可穿透和可重新密封的部分。模具包括在无菌室内的多个模具腔，其形状形成封闭件和主体，以及基本上无菌的表面，其围绕并邻近模具腔的周边延伸。包括端臂工具的组装装置具有可与主体和闭合件中的每一个接合的接合部分，其可相对于模具移动以将基本无菌的闭合件和主体与模腔接合和脱模。柔性屏障耦合到模具和工具，以基本上防止污染物从模制机器和工具通过。

19. 发明申请

US20120076883A1 Sterile De-Molding Apparatus and Method 有权
标题翻译：无菌脱模装置及方法
公开(公告)号：US20120076883A1
公开(公告)日：2012-03-29
申请号：US13311616
申请日：2011-12-06
申请人： Daniel Py , Benoit Adamo , John Guthy , Nathaniel Houle , Giovanni Rodriguez
发明人： Daniel Py , Benoit Adamo , John Guthy , Nathaniel Houle , Giovanni Rodriguez
IPC分类号： B29C45/18
CPC分类号： B29C45/1701 , B29C37/0007 , B29C45/006 , B29C45/1753 , B29C45/40 , B29C45/42 , B29C2045/1797 , B29C2791/005
摘要： At least one of first and second mold portions defines a mold cavity to receive molten plastic and form therefrom at least one molded part, and is movable relative to the other between (i) a closed position for sealing the mold cavity or cavities and molding at least one part therein, and (ii) an open position defining a fluid passageway between the mold portions and permitting the passage of a fluid sterilant therein. A fluid sterilant source is connectable in fluid communication with the fluid passageway for introducing the sterilant therein in the open position, contacting with the sterilant the surfaces of the first and second mold portions forming the fluid passageway and located adjacent to the at least one mold cavity, but not contacting an interior surface of a molded part within the mold cavity, to sterilize the exposed mold surfaces and thereby prevent contamination of the molded part.
摘要翻译：第一和第二模具部分中的至少一个限定了模腔以接收熔融塑料并从其形成至少一个模制部件，并且可以在（i）用于密封模腔或空腔的闭合位置和相对于另一模制部件其中至少一部分，以及（ii）在模具部分之间限定流体通道并允许其中的流体灭菌剂通过的打开位置。流体灭菌剂源可连接到流体通道，用于将灭菌剂在其中引入打开位置，与杀菌剂接触，形成第一和第二模具部分的形成流体通道的表面并且邻近于至少一个模腔但是不与模腔内的模制部件的内表面接触，对暴露的模具表面进行消毒，从而防止模制部件的污染。

20. 发明申请

US20100316774A1 READY TO DRINK CONTAINER WITH NIPPLE AND NEEDLE PENETRABLE AND LASER RESEALABLE PORTION, AND RELATED METHOD 失效
标题翻译：准备饮用容器和针头和可激光部分及相关方法
公开(公告)号：US20100316774A1
公开(公告)日：2010-12-16
申请号：US12861354
申请日：2010-08-23
申请人： Daniel Py , Benoit Adamo , John Guthy , Nathaniel Houle , Brian Tulley , Jeffrey Willey
发明人： Daniel Py , Benoit Adamo , John Guthy , Nathaniel Houle , Brian Tulley , Jeffrey Willey
IPC分类号： A61J9/00 , B65B55/08
CPC分类号： A61J11/0005 , A61J1/1406 , A61J9/003 , A61J11/04 , B65D51/002
摘要： A container is provided for storing a product, such as a fat containing liquid product, and includes a body defining a chamber for receiving the product; and a container closure including a sealing portion for sealing the product within the chamber. The container closure includes a member forming a substantially fluid-tight seal between the container closure and the body; a nipple in fluid communication with the chamber that seals the chamber with respect to the ambient atmosphere during storage of the product in the chamber and that can be opened to dispense product from the chamber therethrough; and a needle penetrable and laser resealable portion that is penetrable by the needle for aseptically filling the chamber with the product, and that is thermally resealable by the application of laser radiation thereto to seal the product within the chamber.
摘要翻译：提供容器用于储存诸如含脂肪的液体产品的产品，并且包括限定用于容纳产品的室的主体; 以及容器封闭件，其包括用于密封腔室内的产品的密封部分。容器封闭件包括在容器封闭件和主体之间形成基本上流体密封的密封件; 与腔室流体连通的乳头，其在产品在腔室中储存期间相对于环境大气密封腔室，并且可以打开以从腔室通过其分配产品; 以及针可穿透和可激光重新密封的部分，其可由针穿透，用于用产品无菌填充腔室，并且通过施加激光辐射可热再密封以密封腔室内的产品。

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