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11. 发明申请

WO2013093024A1 MULTILAYERED WOVEN MANUFACTURE AND USE OF THE MULTILAYER WOVEN MANUFACTURE AS CARRIERS FOR DRIED MATRIX SPOT APPLICATIONS 审中-公开
标题翻译：多层织物制造和多层织物制造作为干燥基质应用的载体
公开(公告)号：WO2013093024A1
公开(公告)日：2013-06-27
申请号：PCT/EP2012/076688
申请日：2012-12-21
申请人： DSM IP ASSETS B.V.
发明人： MENGERINK, Ynze , MOMMERS, Johannes Helena Michael , QIU, Jun
IPC分类号： B32B5/26 , G01N33/48
CPC分类号： B32B5/024 , B01J20/28023 , B01J20/28033 , B01J20/28035 , B01J20/28038 , B01J20/28052 , B01J20/28054 , B01J20/28095 , B01L3/508 , B01L2200/12 , B01L2300/069 , B01L2300/0816 , B01L2300/0874 , B01L2300/0887 , B01L2400/0406 , B32B5/12 , B32B5/26 , B32B2250/20 , B32B2262/0276 , B32B2307/728 , G01N33/48 , G01N33/5302 , Y10T428/24074 , Y10T428/24091 , Y10T428/24099 , Y10T428/24107 , Y10T428/24124 , Y10T428/24132 , Y10T428/24322 , Y10T428/24967 , Y10T442/153 , Y10T442/2484 , Y10T442/3179 , Y10T442/3472 , Y10T442/3528 , Y10T442/3667 , Y10T442/3976
摘要： The invention relates to a substantially laminary manufacture comprising 2 substantially laminary layers in contact, wherein the layers comprise a woven, hydrophilic material.
摘要翻译：本发明涉及包括2个基本上接触层的层的大体上的层叠制造方法，其中层包括编织的亲水材料。

12. 发明公开

EP4127046A1 INJECTION MOLDED PARTS 审中-实审
公开(公告)号：EP4127046A1
公开(公告)日：2023-02-08
申请号：EP21713431.1
申请日：2021-03-25
申请人： DSM IP Assets B.V.
发明人： CREVECOEUR, Jeroen, Joost , QIU, Jun
IPC分类号： C08K7/14 , C08G75/0204 , C08L81/02

13. 发明公开

EP2346952A1 ANTIFOULING COATING COMPOSITION COMPRISING FUNCTIONALIZED NANOPARTICULES 审中-公开
标题翻译：具有功能纳米颗粒防污漆
公开(公告)号：EP2346952A1
公开(公告)日：2011-07-27
申请号：EP09741319.9
申请日：2009-10-30
申请人： DSM IP Assets B.V.
发明人： QIU, Jun , de RIJK, Ronnie Bernardus Maria , THIES, Jens Christoph
IPC分类号： C09D5/16 , C09D7/12 , C09C1/30 , C09C3/10
CPC分类号： C09C1/3081 , B82Y30/00 , C01G23/047 , C01P2004/64 , C01P2004/84 , C09C1/043 , C09C1/3684 , C09C1/40 , C09C3/12 , C09D5/1637 , C09D5/1687 , Y10T428/31507 , Y10T428/31544 , Y10T428/31663 , Y10T428/31678 , Y10T428/31721 , Y10T428/31739 , Y10T428/31786 , Y10T428/31855 , Y10T428/31935 , Y10T428/31938
摘要： Method for providing a substrate with an anti-biofouling coating the method comprising: a. obtaining a coating composition comprising nanoparticles being grafted with reactive groups and hydrophilic polymer chains and a solvent; b. applying the coating composition to the substrate; and c. optionally curing the coating composition. herein the surface tension of the coating composition at 25°C is below 40 mN/m.

14. 发明公开

EP2794260A1 MULTILAYERED WOVEN MANUFACTURE AND USE OF THE MULTILAYER WOVEN MANUFACTURE AS CARRIERS FOR DRIED MATRIX SPOT APPLICATIONS 审中-公开
标题翻译：多层编织制造和使用多层编织制造作为干燥矩阵点应用的载体
公开(公告)号：EP2794260A1
公开(公告)日：2014-10-29
申请号：EP12813368.3
申请日：2012-12-21
申请人： DSM IP Assets B.V.
发明人： MENGERINK, Ynze , MOMMERS, Johannes Helena Michael , QIU, Jun
IPC分类号： B32B5/26 , G01N33/48
CPC分类号： B32B5/024 , B01J20/28023 , B01J20/28033 , B01J20/28035 , B01J20/28038 , B01J20/28052 , B01J20/28054 , B01J20/28095 , B01L3/508 , B01L2200/12 , B01L2300/069 , B01L2300/0816 , B01L2300/0874 , B01L2300/0887 , B01L2400/0406 , B32B5/12 , B32B5/26 , B32B2250/20 , B32B2262/0276 , B32B2307/728 , G01N33/48 , G01N33/5302 , Y10T428/24074 , Y10T428/24091 , Y10T428/24099 , Y10T428/24107 , Y10T428/24124 , Y10T428/24132 , Y10T428/24322 , Y10T428/24967 , Y10T442/153 , Y10T442/2484 , Y10T442/3179 , Y10T442/3472 , Y10T442/3528 , Y10T442/3667 , Y10T442/3976
摘要： The invention relates to a substantially laminary manufacture comprising 2 substantially laminary layers in contact, wherein the layers comprise a woven, hydrophilic material.
摘要翻译：本发明涉及包括2个基本上层压的层接触的基本上薄片状的制造，其中所述层包含织造的亲水材料。

15. 发明公开

EP2411477A1 IMPROVED ANTI-BIOFOULING COATING 审中-公开
标题翻译：改善的抗生物附着涂料
公开(公告)号：EP2411477A1
公开(公告)日：2012-02-01
申请号：EP10711209.6
申请日：2010-03-25
申请人： DSM IP Assets B.V.
发明人： BUSKENS, Pascal Jozef Paul , VERMEULEN, Jacobus Adriaan Antonius , RIJK, de, Ronnie , THIES, Jens Christoph , QIU, Jun
IPC分类号： C09D5/16 , C08J7/04 , C09D201/00 , C08G83/00
CPC分类号： C08F283/12 , C08F291/00 , C08J7/047 , C08L51/003 , C08L51/085 , C09D5/1637 , C09D151/003 , C09D151/085 , C09D201/005 , C08L2666/02
摘要： The invention relates to a coating material suitable for providing a substrate with an anti-biofouling coating, the coating material comprising a macromolecule comprising: (A) a macromolecular scaffold comprising a reactive group capable of undergoing a Michael type reaction between a Michael type acceptor group and a Michael type donor group, (B) at least one functional moiety attached to the macromolecular scaffold, said at least one functional moiety comprising a hydrophilic moiety, wherein the functional moiety is derivable from a Michael type reaction, involving the reactive group on the macromolecular scaffold and a reactive hydrophilic moiety and (C) at least one moiety capable of crosslinking the coating material.

16. 发明公开

EP2217357A2 HIGH PERFORMANCE MEMBRANE 失效
标题翻译：聚乙烯薄膜麻醉多糖BESCHICHTUNG
公开(公告)号：EP2217357A2
公开(公告)日：2010-08-18
申请号：EP08850102.8
申请日：2008-11-14
申请人： DSM IP Assets B.V.
发明人： QIU, Jun , RULKENS, Rudy , KAMP, OP DEN, Johannes Leonardus Maria , THIES, Jens Christoph
IPC分类号： B01D67/00 , B01D69/12
CPC分类号： B01D67/0088 , B01D69/02 , B01D71/26 , B01D71/56 , B01D2323/02 , B01D2325/22 , B01D2325/24 , H01M2/145 , H01M2/1653
摘要： The invention relates to a micro-porous membrane comprising a porous membrane carrier made of a first polymeric material (A) and comprising a second polymeric material (B) intimately divided throughout the porous membrane carrier, wherein the porous membrane carrier comprises a plurality of interconnected polymeric fibers, fibrils, filaments and/or lamellae having a thickness of less than 1 µm, the porous membrane carrier has an interconnected open porous structure formed by the plurality of interconnected polymeric fibers, fibrils, filaments and/or lamellae and a porosity of at least 50%; and the polymeric material (B) comprises a thermoplastic polycondensation polymer and is present in an amount of at most 30 wt.%, relative to the total weight of (A) and (B). The invention also relates to a process for preparing such a micro-porous membrane comprising steps wherein (i) a porous membrane carrier made of a first polymeric material (A) is impregnated with a polymer solution comprising a second polymeric material (B) in a solvent system (X), and (ii) the resulting impregnated membrane carrier is quenched in a non-solvent system (Y), thereby precipitating at least part of the second polymeric material (B).
摘要翻译：本发明涉及一种改性多孔膜的方法，包括以下步骤：（a）具有开孔结构的多孔膜载体（A）用包含聚合物（B-1）在溶剂中的溶液（X）浸渍（X-1），其中聚合物（B-1）可溶，从而形成浸渍有聚合物溶液（X）的多孔膜载体，并且由浸渍溶液组成的聚合物（B-1）的至少一部分是通过用包含用于所述聚合物的非溶剂（Y-1）的液体（Y）进行淬火从溶液中沉淀出来。本发明还涉及包含多孔膜载体（A）和聚合物材料（B）的微孔膜，所述聚合物材料（B）包含在整个多孔膜载体上密切分布的缩聚聚合物，其中聚合物材料包含缩聚聚合物，以及制备所述膜的方法及其用途。

17. 发明公开

EP3423511A1 ANTI-FOULING AND SPECIFIC BINDING SURFACE, DISPERSIONS COMPRISING PARTICLES HAVING SUCH SURFACES, AND METHODS OF MAKING THESE 有权
公开(公告)号：EP3423511A1
公开(公告)日：2019-01-09
申请号：EP17707909.2
申请日：2017-03-03
申请人： DSM IP Assets B.V.
发明人： ZONG, Mengmeng , DIAS, Aylvin Jorge Angelo Athanasius , VAN DEN BOSCH, Edith Elisabeth M , QIU, Jun
IPC分类号： C08G73/02

18. 发明授权

EP2217357B1 POLYETHYLENE MEMBRANE WITH POLYAMIDE COATING 失效
标题翻译：带聚酰胺涂层的聚乙烯膜
公开(公告)号：EP2217357B1
公开(公告)日：2017-10-11
申请号：EP08850102.8
申请日：2008-11-14
申请人： DSM IP Assets B.V.
发明人： QIU, Jun , RULKENS, Rudy , KAMP, OP DEN, Johannes Leonardus Maria , THIES, Jens Christoph
IPC分类号： B01D69/02 , B01D71/26 , H01M2/14
CPC分类号： B01D67/0088 , B01D69/02 , B01D71/26 , B01D71/56 , B01D2323/02 , B01D2325/22 , B01D2325/24 , H01M2/145 , H01M2/1653

19. 发明公开

EP2576031A1 MEMBRANE SUITABLE FOR BLOOD FILTRATION 审中-公开
标题翻译： MEMBRAN ZUR BLUTFILTRATION
公开(公告)号：EP2576031A1
公开(公告)日：2013-04-10
申请号：EP11722446.9
申请日：2011-05-31
申请人： DSM IP Assets B.V.
发明人： DULLAERT, Konraad , DORSCHU, Marko , QIU, Jun , THIES, Jens Christoph
IPC分类号： B01D71/56 , B01D67/00 , B01D69/10 , D01F6/60 , D01F6/80 , D01F6/90 , B01D39/16
CPC分类号： B01D71/56 , B01D65/08 , B01D67/0088 , B01D69/12 , B01D71/26 , B01D2239/025 , B01D2239/1233 , B01D2321/28 , B01D2323/39 , B01D2325/36 , D01F6/60 , D01F6/80 , D01F6/90 , D04H1/728 , G01N33/491
摘要： The invention relates to a membrane construction comprising multiple layers wherein at least one of the layers is a nanoweb made of polymeric nanofibers, wherein the mean flow pore size of the nanoweb is in the range from 50 nm to 5 mum, wherein the number average diameter of the nanofibers is in the range from 100 to 600 nm, wherein the basis weight of the nanoweb is in the range from 1 to 20 g/m2, wherein the porosity of the nanoweb is in the range from 60 to 95%, wherein at least one of the layers is a support layer and wherein the nanoweb is hydrophilic.
摘要翻译：本发明涉及包括多个层的膜结构，其中至少一个层是由聚合物纳米纤维制成的纳米网，其中纳米纤维网的平均流动孔径在50nm至5μm的范围内，其中数均直径的纳米纤维的范围在100至600nm的范围内，其中纳米纤维网的基重在1至20g / m 2的范围内，其中纳米纤维网的孔隙率在60至95％的范围内，其中在层中的至少一层是支撑层，其中纳米网是亲水性的。

20. 发明申请

WO2005119252A2 GPR35 AND MODULATORS THEREOF FOR THE TREATMENT OF METABOLIC-RELATED DISORDERS 审中-公开
标题翻译： GPR35的调节剂用于治疗与代谢相关的疾病
公开(公告)号：WO2005119252A2
公开(公告)日：2005-12-15
申请号：PCT/US2005/018082
申请日：2005-05-23
申请人： ARENA PHARMACEUTICALS, INC. , LEONARD, James N. , CHU, Zhi Liang , UNETT, David J. , GATLIN, Joel E. , GAIDAROV, Ibragim , QIU, Jun , SKINNER, Philip J. , BOATMAN, P. Douglas
发明人： LEONARD, James N. , CHU, Zhi Liang , UNETT, David J. , GATLIN, Joel E. , GAIDAROV, Ibragim , QIU, Jun , SKINNER, Philip J. , BOATMAN, P. Douglas
IPC分类号： G01N33/50
CPC分类号： G01N33/6893 , A61K31/425 , G01N2333/726 , G01N2500/00
摘要： The present invention relates to a method for identifying a metabolic stabilizing compound, comprising: a) contacting a candidate compound with GPR35, and b) determining whether GPR35 functionality is increased, wherein an increase in GPR35 functionality is indicative of the candidate compound being a metabolic stabilizing compound. The invention further relates to use of a GPR35 modulator for the manufacture of a medicament for use as a metabolic stabilizing agent. In addition, the invention relates to a method for increasing GPR35 function, comprising contacting GPR35 with an effective amount of a compound of Formula (I): or a pharmaceutically acceptable salt thereof, wherein X is O or S; and R1, R2, R3, R4, and R5 are each independently selected from the group consisting of H, C1-4 alkoxy, C1-4 alkyl, halogen, hydroxyl, and nitro; wherein said C1-4 alkoxy is optionally substituted with carbo-C1-4-alkoxy or carboxy.
摘要翻译：本发明涉及用于鉴定代谢稳定化合物的方法，包括：a）使候选化合物与GPR35接触，和b）确定GPR35的功能是否增加，其中GPR35功能的增加指示候选化合物是代谢稳定化合物。本发明还涉及GPR35调节剂在制备用作代谢稳定剂的药物中的用途。另外，本发明涉及增加GPR35功能的方法，包括使GPR35与有效量的式（I）化合物或其可药用盐接触，其中X为O或S; R 1，R 2，R 3，R 4和R 5各自独立地选自H，C 1-4烷氧基，C 1-4烷基，卤素，羟基和硝基; 其中所述C 1-4烷氧基任选被C 1-4 - 烷氧基或羧基取代。

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