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11. 发明申请

US20070299445A1 SPINE TREATMENT DEVICES AND METHODS 审中-公开
标题翻译：脊柱治疗装置和方法
公开(公告)号：US20070299445A1
公开(公告)日：2007-12-27
申请号：US11767402
申请日：2007-06-22
申请人： John Shadduck , Csaba Truckai , Robert Luzzi
发明人： John Shadduck , Csaba Truckai , Robert Luzzi
IPC分类号： A61B17/58
CPC分类号： A61B17/7059 , A61B17/7011 , A61B17/7044 , A61B17/7055 , A61B17/7067 , A61B2017/00867
摘要： A modular implant system and method for dynamic stabilization of a spine segment that can be implanted in a minimally invasive posterior approach. In one embodiment, the implant device has an inferior body portion configured for fixation in a sacrum or ilium and a superior body portion configured for engaging one or more spinous processes to limit extension and optionally flexion while off-loading a spine segment. The implant system can be configured to stabilize a spine segment, re-distribute loads with the spine segment and still allow spine lateral bending and torsion. Besides being far less invasive than other procedures, the system and method is reversible and adjustable post-implant.
摘要翻译：用于动态稳定脊柱段的模块化植入物系统和方法，其可以以微创后路方法植入。在一个实施例中，植入装置具有被配置为固定在骶骨或髂骨中的下主体部分和被配置为接合一个或多个棘突以限制延伸和可选地屈曲同时卸载脊椎段的上身部分。植入系统可以被配置为稳定脊柱段，使用脊柱部分重新分布负载，并且还允许脊柱横向弯曲和扭转。除了其他程序的侵入性要小得多，该系统和方法是可逆的和可调整的植入后。

12. 发明申请

US20060122625A1 Bone treatment systems and methods 有权
标题翻译：骨治疗系统和方法
公开(公告)号：US20060122625A1
公开(公告)日：2006-06-08
申请号：US11209035
申请日：2005-08-22
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61F2/34
CPC分类号： A61B17/8805 , A61B17/70 , A61B17/8822 , A61B17/8827 , A61B17/8836 , A61B2017/00022 , A61B2017/00026 , A61B2017/00084 , A61B2017/564 , A61F2/44
摘要： The present invention relates in certain embodiments to medical devices for treating vertebral compression fractures. More particularly, embodiments of the invention relate to instruments and methods for controllably restoring vertebral body height by controlling the flow of bone cement into the interior of a vertebra and the application of forces causes by the cement flow. An exemplary system utilizes Rf energy in combination a conductive bone cement for selectively polymerizing the inflow plume to increase the viscosity of the cement. In one aspect of the invention, the system utilizes a controller to control bone cement flow parameters to either allow or disallow cement interdigitation into cancellous bone. A method of the invention includes pulsing the flows of bone cement wherein high acceleration of the flow pulses can apply expansion forces across the surface of the cement plume to reduce a vertebral fracture.
摘要翻译：本发明在某些实施例中涉及用于治疗脊椎压缩性骨折的医疗装置。更具体地，本发明的实施例涉及通过控制骨水泥进入椎骨内部并且由水泥流引起的力的施加来可控地恢复椎体高度的仪器和方法。示例性系统利用结合导电骨水泥的Rf能量来选择性聚合流入羽流以增加水泥的粘度。在本发明的一个方面，该系统利用控制器来控制骨水泥流动参数以允许或不允许水泥交叉指向松质骨。本发明的方法包括脉动骨粘固剂的流动，其中流动脉冲的高加速度可以施加穿过水泥羽流表面的膨胀力，以减少椎骨骨折。

13. 发明申请

US20060106459A1 Bone treatment systems and methods 审中-公开
标题翻译：骨治疗系统和方法
公开(公告)号：US20060106459A1
公开(公告)日：2006-05-18
申请号：US11215730
申请日：2005-08-30
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61F2/44
CPC分类号： A61B17/8836 , A61B17/7095 , A61B17/7098
摘要： A system for treating an abnormal vertebral body such as a compression fracture. In an exemplary embodiment, the system includes a biocompatible flow-through implant structure configured with a three-dimensional interior web that defines flow openings therein for cooperating with a two-part hardenable bone cement. The flow-through structure is capable of compacted and extended shapes and in one embodiment provides a gradient in flow openings for controlling flow parameters of a bone cement injected under high pressure into the interior thereof. The flow-through implant structure is configured for transducing cement injection forces into a selected direction for moving apart cortical endplates of a vertebra to reduce a fracture. In one embodiment, the flow-through implant structure is coupled to an Rf source for applying Rf energy to a two-part bone cement to accelerate curing of the cement to thereby allow on-demand alterations of cement viscosity. The Rf system allows for control of bone cement polymerization globally or regionally to prevent cement extravasion and to direct forces applied to a vertebra to reduce a fracture.
摘要翻译：用于治疗异常椎体的系统，例如压缩性骨折。在一个示例性实施例中，该系统包括生物相容性流通植入结构，该植入结构被构造成具有限定其中的流动开口的三维内部腹板，用于与两部分可硬化骨粘固剂配合。流通结构能够压实和延伸形状，并且在一个实施例中提供流动开口中的梯度，用于控制在高压下注入其内部的骨粘固剂的流动参数。流通植入结构被配置为将水泥注射力转换到选定的方向以移动分开的椎骨的皮层终板以减少骨折。在一个实施例中，流过植入结构耦合到Rf源，以将Rf能量施加到两部分骨水泥以加速水泥的固化，从而允许水泥粘度的按需改变。 Rf系统允许全局或区域地控制骨水泥聚合，以防止水泥外渗，并引导施加到椎骨上的力以减少骨折。

14. 发明申请

US20050267464A1 Electrosurgical instrument and method of use 审中-公开
标题翻译：电外科仪器及使用方法
公开(公告)号：US20050267464A1
公开(公告)日：2005-12-01
申请号：US10973818
申请日：2004-10-25
申请人： Csaba Truckai , John Shadduck , Bruno Strul , James Baker
发明人： Csaba Truckai , John Shadduck , Bruno Strul , James Baker
IPC分类号： A61B18/14
CPC分类号： A61B18/1442 , A61B2018/00619
摘要： An embodiment of a method of the invention provides a method for welding tissue comprising providing a tissue welding device having first and second tissue engaging surfaces with at least one surface including an electrode surface that defines a plurality of surface portions having different resistances to electrical current flow therethrough. A target tissue volume is engaged with the tissue engaging surfaces. Rf energy is delivered to the target volume to create a substantially even temperature distribution across at least a portion of the target tissue volume to substantially uniformly weld at least a portion of the target tissue volume.
摘要翻译：本发明的方法的一个实施例提供了一种焊接组织的方法，包括提供具有第一和第二组织接合表面的组织焊接装置，其中至少一个表面包括限定对电流流动具有不同电阻的多个表面部分的电极表面通过。目标组织体积与组织接合表面接合。将Rf能量传递到目标体积以在目标组织体积的至少一部分上产生基本均匀的温度分布，以基本均匀地焊接目标组织体积的至少一部分。

15. 发明申请

US20050192568A1 Electrosurgical jaw structure for controlled energy delivery 有权
标题翻译：用于受控能量输送的电外科钳口结构
公开(公告)号：US20050192568A1
公开(公告)日：2005-09-01
申请号：US11118881
申请日：2005-04-29
申请人： Csaba Truckai , James Baker , Bruno Strul , John Shadduck
发明人： Csaba Truckai , James Baker , Bruno Strul , John Shadduck
IPC分类号： A61B18/14
CPC分类号： A61B18/1442 , A61B2018/00077 , A61B2018/00083 , A61B2018/00148 , A61B2018/0063 , A61B2018/00809
摘要： A working end of a surgical instrument that carries first and second jaws for delivering energy to tissue. In a preferred embodiment, at least one jaw of the working end defines a tissue-engagement plane that contacts the targeted tissue. The cross-section of the engagement plane reveals that it defines a surface conductive portion that overlies a variably resistive matrix of a temperature-sensitive resistive material or a pressure-sensitive resistive material. An interior of the jaw carries a conductive material or electrode that is coupled to an Rf source and controller. In an exemplary embodiment, the variably resistive matrix can comprise a positive temperature coefficient (PTC) material, such as a ceramic, that is engineered to exhibit a dramatically increasing resistance (i.e., several orders of magnitude) above a specific temperature of the material.
摘要翻译：手术器械的工作端，其携带用于将能量递送至组织的第一和第二钳口。在优选实施例中，工作端的至少一个钳口限定了接触目标组织的组织接合平面。接合平面的横截面显示它限定了覆盖在温度敏感电阻材料或压敏电阻材料的可变电阻矩阵上的表面导电部分。钳口的内部承载耦合到Rf源和控制器的导电材料或电极。在示例性实施例中，可变电阻矩阵可以包括正温度系数（PTC）材料，例如陶瓷，其被工程化以显示高于材料的特定温度的显着增加的电阻（即几个数量级）。

16. 发明授权

US08075558B2 Electrosurgical instrument and method 有权
标题翻译：电外科仪器和方法
公开(公告)号：US08075558B2
公开(公告)日：2011-12-13
申请号：US11173878
申请日：2005-07-02
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61B18/14
CPC分类号： A61B18/1445 , A61B17/320016 , A61B17/3201 , A61B18/08 , A61B18/085 , A61B18/1442 , A61B18/1815 , A61B2017/00084 , A61B2017/2933 , A61B2017/2934 , A61B2017/2945 , A61B2017/320064 , A61B2018/00107 , A61B2018/00619 , A61B2018/0063 , A61B2018/00702 , A61B2018/00791 , A61B2018/1432
摘要： An electrosurgical working end and method for sealing and transecting tissue. An exemplary working end provides curved jaw members that are positioned on opposing sides of the targeted anatomic structure. The working end carries a slidable extension member having flange portions with inner surfaces that slide over the jaw members to clamp tissue therebetween. The working end carries an independent slidable cutting member that is flexible to follow the curved axis of the jaws. The electrosurgical surfaces of the jaws include partially-resistive bodies for carrying a current or load which modulates ohmic heating in the engaged tissue to prevent charring and desiccation of tissue to create a high strength thermal seal.
摘要翻译：电外科工作端及组织密封和横切方法。示例性工作端提供定位在目标解剖结构的相对侧上的弯曲钳口构件。工作端承载有可滑动的延伸构件，其具有凸缘部分，其内表面在钳口构件上滑动以在其间夹紧组织。工作端具有独立的可滑动切割构件，其可挠曲地沿着夹爪的弯曲轴线。钳口的电外科表面包括用于承载电流或负载的部分电阻体，其调节接合组织中的欧姆加热，以防止组织的烧焦和干燥以产生高强度热密封。

17. 发明申请

US20080027456A1 Bone treatment systems and methods 审中-公开
标题翻译：骨治疗系统和方法
公开(公告)号：US20080027456A1
公开(公告)日：2008-01-31
申请号：US11880475
申请日：2007-07-19
申请人： Csaba Truckai , Robert Luzzi , John Shadduck , Eric Buehlmann
发明人： Csaba Truckai , Robert Luzzi , John Shadduck , Eric Buehlmann
IPC分类号： A61B17/58
CPC分类号： A61B17/8836 , A61B17/8811 , A61B2017/00022
摘要： A bone cement injector used for treating vertebral compression fractures has diamond-like coatings or amorphous carbon based coatings with a high hardness and a low coefficient of friction on an interior flow channel thereof. Such a bone cement injector includes a sensor system for sensing retrograde bone cement flows that can migrate along a fractured path toward a pedicle and risk leakage into the spinal canal. An energy delivery system can be coupled to the injector for applying energy to tissue and/or to bone cement that migrates in a retrograde direction, wherein the energy polymerizes the cement and/or coagulates tissue to inhibit further retrograde cement migration.
摘要翻译：用于治疗椎体压缩骨折的骨水泥注射器具有金刚石状涂层或其内部流动通道具有高硬度和低摩擦系数的无定形碳基涂层。这种骨水泥注射器包括用于感测逆行骨水泥流的传感器系统，其可以沿着骨折路径朝向椎弓根移动并且有可能泄漏到椎管内。能量递送系统可以耦合到注射器，以将能量施加到沿逆行方向迁移的组织和/或骨水泥，其中能量聚合水泥和/或凝结组织以抑制进一步逆行水泥迁移。

18. 发明申请

US20080021466A1 SPINE TREATMENT DEVICES AND METHODS 审中-公开
标题翻译：脊柱治疗装置和方法
公开(公告)号：US20080021466A1
公开(公告)日：2008-01-24
申请号：US11781051
申请日：2007-07-20
申请人： John Shadduck , Csaba Truckai , Robert Luzzi
发明人： John Shadduck , Csaba Truckai , Robert Luzzi
IPC分类号： A61B17/58 , A61B17/08 , A61F2/44 , A61B17/56
CPC分类号： A61B17/7062 , A61B17/08 , A61B17/7041
摘要： A modular implant device and method for dynamic stabilization of a spine segment that can be implanted in a minimally invasive posterior approach. The implant device has superior and inferior body portions configured for engaging two spaced apart spinous processes to limit extension and, optionally, flexion while off-loading a spine segment. The implant device can stabilize a spine segment, re-distribute loads with the spine segment and still allow spine lateral bending and torsion. Implantation of the device is reversible and adjustable post-implantation.
摘要翻译：用于动态稳定脊柱段的模块化植入装置和方法，其可植入微创后路。植入装置具有优良的和较差的主体部分，其构造成用于接合两个间隔开的棘突以限制延伸，并且可选地，在卸载脊椎段的同时弯曲。植入装置可以稳定脊柱段，用脊柱段重新分配载荷，并且还允许脊柱横向弯曲和扭转。装置的植入是可植入后可逆的和可调节的。

19. 发明申请

US20080021465A1 SPINE TREATMENT DEVICES AND METHODS 审中-公开
标题翻译：脊柱治疗装置和方法
公开(公告)号：US20080021465A1
公开(公告)日：2008-01-24
申请号：US11780967
申请日：2007-07-20
申请人： John Shadduck , Csaba Truckai , Robert Luzzi
发明人： John Shadduck , Csaba Truckai , Robert Luzzi
IPC分类号： A61B17/58 , A61B17/56
CPC分类号： A61B17/866 , A61B17/7002 , A61B17/864 , A61B17/8685 , A61B2017/00867
摘要： A spine implant device for fusion or dynamic stabilization of a spine segment can include a fixation device with a shaft portion for engaging bone and a proximal end for coupling to a rod that allows for limited flexing of the proximal end relative to the shaft portion. A spine implant system and method utilizing such a bone fixation device can include an energy delivery mechanism for on-demand curing of bone cement delivered through the bone fixation device into a bone.
摘要翻译：用于脊柱段的融合或动态稳定的脊柱植入装置可以包括具有用于接合骨的轴部分的固定装置和用于联接到杆的近端，其允许近端相对于轴部分的有限的弯曲。使用这种骨固定装置的脊柱植入系统和方法可以包括能量输送机构，用于按照骨骼固定装置输送骨骼的骨水泥按需固化。

20. 发明申请

US20070213704A1 ELECTRICAL DISCHARGE DEVICES AND TECHNIQUES FOR MEDICAL PROCEDURES 审中-公开
标题翻译：电子放电设备和医疗程序的技术
公开(公告)号：US20070213704A1
公开(公告)日：2007-09-13
申请号：US11735318
申请日：2007-04-13
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61B18/18
CPC分类号： A61B17/22004 , A61B18/042 , A61B2017/22008 , A61B2018/1213
摘要： A medical instrument coupled to first and second energy means and a computer controller for the controlled volumetric removal of thin tissue layers. The system provides a source for introducing a gas to controllably form and capture transient gas volumes in a microchannel structure at the working surface of the instrument that interfaces with a targeted tissue site. Each of the microchannel features of the working surface carries an electrode element coupled to the electrical source. The energy may be applied to the targeted site in either of two modes of operation, depending in part on voltage and repetition rate of energy delivery. In one mode of energy application, electrical potential is selected to cause an intense electrical arc across the transient ionized gas volumes to cause an energy-tissue interaction characterized by tissue vaporization. In another preferred mode of energy delivery, the system applies selected levels of energy to the targeted site by means of an energetic plasma at the instrument working surface to cause molecular volatilization of surface macromolecules thus resulting in material removal. Both modes of operation limit collateral thermal damage to tissue volumes adjacent to the targeted site. Another preferred embodiment provides and an ultrasound source or other vibrational source coupled to the working end to cause cavitation in fluid about the working end.
摘要翻译：耦合到第一和第二能量装置的医疗器械和用于受控体积移除薄组织层的计算机控制器。该系统提供用于引入气体的源，以可控地形成并捕获与目标组织部位相接触的仪器工作表面处的微通道结构中的瞬态气体体积。工作表面的每个微通道特征带有耦合到电源的电极元件。能量可以以两种操作模式中的任一种施加到目标位置，部分取决于能量传递的电压和重复率。在一种能量应用模式中，选择电势以在瞬态电离气体体积上引起强烈的电弧以引起以组织蒸发为特征的能量 - 组织相互作用。在另一种优选的能量输送模式中，系统通过仪器工作表面上的能量等离子体将选择的能量施加到目标部位，从而导致表面大分子的分子挥发，从而导致材料去除。两种操作模式都限制了与目标部位相邻的组织体积的附带热损伤。另一个优选实施例提供了耦合到工作端的超声源或其他振动源，以在工作端周围引起流体中的空化。

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