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11. 发明申请

US20110295185A1 Intestinal Brake Inducing Intraluminal Therapeutic Substance Eluting Devices and Methods 有权
标题翻译：肠制动诱导腔内治疗物质洗脱装置及方法
公开(公告)号：US20110295185A1
公开(公告)日：2011-12-01
申请号：US13104313
申请日：2011-05-10
申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , Prasanna Malaviya , Glenda C. Marsh , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , James W. Voegele , Lauren S. Weaner , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , Prasanna Malaviya , Glenda C. Marsh , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , James W. Voegele , Lauren S. Weaner , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
IPC分类号： A61M37/00 , A61K31/20 , A61M5/00 , A61F2/00 , A61M5/168 , A61N1/36
CPC分类号： A61M31/002 , A61F2/04 , A61F5/0013 , A61F5/0026 , A61F2002/045 , A61K9/0065 , A61M5/14276 , A61M39/0208 , A61M2210/106 , A61M2210/1064 , A61N1/0509 , A61N1/36007 , A61N1/37205
摘要： Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems and ingestible pills. In one embodiment, a method of producing satiety comprising the steps of accessing a gastrointestinal tract of a patient and implanting an intraintestinal therapeutic substance eluting implant. The implant is capable of eluting a satiety inducing substance selected from at least one of a nutrient, a specific satiety inducing bio-active substance, pancreatic polypeptides, free fatty acids, cholecystokinin, amino acids, glutamine, lipids, linoleic acid, or a combination thereof, from the implant into the gastrointestinal tract.
摘要翻译：方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。这些方法和装置通过稳定的可植入系统和可摄取的药丸来实现。在一个实施方案中，产生饱腹感的方法包括以下步骤：进入患者的胃肠道并植入肠内治疗物质洗脱植入物。植入物能够洗脱选自营养物，特定饱腹感生物活性物质，胰腺多肽，游离脂肪酸，缩胆囊素，氨基酸，谷氨酰胺，脂质，亚油酸或组合中的至少一种的饱腹感受物质从植入物到胃肠道。

12. 发明申请

US20130041389A1 GASTRIC BAND WITH OVERMOLD 有权
公开(公告)号：US20130041389A1
公开(公告)日：2013-02-14
申请号：US13205853
申请日：2011-08-09
申请人： Stephen M. Torain , Harry E. Payne , Jeffrey P. Wiley , Lauren S. Weaner
发明人： Stephen M. Torain , Harry E. Payne , Jeffrey P. Wiley , Lauren S. Weaner
IPC分类号： A61B17/12
CPC分类号： A61F5/0056
摘要： A gastric band comprises a bladder having an opening, an insertable component to fluidly seal the opening, and a strap that may be overmolded onto the bladder. The insertable component may be a grommet or a plug. Additionally, the insertable component may be coupled to a support member via a living hinge. In another configuration, the insertable component comprises a grommet and a suture loop at least partially formed within the grommet. A band may be provided instead of the strap, with the band having a grommet aperture formed through a deck such that the grommet may be inserted into the opening of the bladder. An overmolded shell having a latching member may be overmolded onto the deck to secure the grommet and a portion of the suture loop therein. The gastric band may further be coupled to a flexible conduit and an injection port.
摘要翻译：胃带包括具有开口的囊，用于流体地密封开口的可插入部件，以及可以包覆模制到囊上的带子。可插入部件可以是索环或塞子。另外，可插入部件可以经由活动铰链连接到支撑部件。在另一种构造中，可插入部件包括至少部分地形成在护环内的索环和缝线环。可以提供带而不是带，带具有通过甲板形成的索环孔，使得索环可以插入到囊的开口中。具有闩锁构件的包覆成型的壳可以包覆成型到甲板上，以将索环和缝合线环的一部分固定在其中。胃带还可以连接到柔性导管和注射端口。

13. 发明授权

US08663255B2 Gastric band with overmold 有权
标题翻译：胃肠带包覆成型
公开(公告)号：US08663255B2
公开(公告)日：2014-03-04
申请号：US13205853
申请日：2011-08-09
申请人： Stephen M. Torain , Harry E. Payne , Jeffrey P. Wiley , Lauren S. Weaner
发明人： Stephen M. Torain , Harry E. Payne , Jeffrey P. Wiley , Lauren S. Weaner
IPC分类号： A61B17/12
CPC分类号： A61F5/0056
摘要： A gastric band comprises a bladder having an opening, an insertable component to fluidly seal the opening, and a strap that may be overmolded onto the bladder. The insertable component may be a grommet or a plug. Additionally, the insertable component may be coupled to a support member via a living hinge. In another configuration, the insertable component comprises a grommet and a suture loop at least partially formed within the grommet. A band may be provided instead of the strap, with the band having a grommet aperture formed through a deck such that the grommet may be inserted into the opening of the bladder. An overmolded shell having a latching member may be overmolded onto the deck to secure the grommet and a portion of the suture loop therein. The gastric band may further be coupled to a flexible conduit and an injection port.
摘要翻译：胃带包括具有开口的囊，用于流体地密封开口的可插入部件，以及可以包覆模制到囊上的带子。可插入部件可以是索环或塞子。另外，可插入部件可以经由活动铰链连接到支撑部件。在另一种构造中，可插入部件包括至少部分地形成在护环内的索环和缝线环。可以提供带而不是带，带具有通过甲板形成的索环孔，使得索环可以插入到囊的开口中。具有闩锁构件的包覆成型的壳可以包覆成型到甲板上，以将索环和缝合线环的一部分固定在其中。胃带还可以连接到柔性导管和注射端口。

14. 发明授权

US07367937B2 Gastric band 有权
标题翻译：胃带
公开(公告)号：US07367937B2
公开(公告)日：2008-05-06
申请号：US11364362
申请日：2006-03-01
申请人： Kristin L. Jambor , Jeffrey P. Wiley , Lauren S. Weaner , Mark Tsonton , Patrick J. Swindon
发明人： Kristin L. Jambor , Jeffrey P. Wiley , Lauren S. Weaner , Mark Tsonton , Patrick J. Swindon
IPC分类号： A61F2/00
CPC分类号： A61F5/005 , A61B17/1327 , A61B2017/0042 , A61F5/0053 , A61F5/0066
摘要： A gastric band includes a balloon shaped and dimensioned to circumscribe the stomach at a predetermined location. The balloon includes a longitudinally extending body and a supply tube is secured to the balloon for fluid communication with an internal cavity of the balloon.
摘要翻译：胃带包括一个形状和尺寸适于围绕预定位置的胃的气球。气囊包括纵向延伸的主体，并且供应管固定到球囊上以与球囊的内腔流体连通。

15. 发明申请

US20110040309A1 IMPLANTABLE RESTRICTION DEVICE WITH SPACER 审中-公开
标题翻译：带间隔的可植入限制装置
公开(公告)号：US20110040309A1
公开(公告)日：2011-02-17
申请号：US12541579
申请日：2009-08-14
申请人： Daniel F. Dlugos, JR. , Chad P. Boudreaux , Robert P. Gill , Steven G. Hall , Christopher J. Hess , Jerome R. Morgan , Frederick E. Shelton, IV , Jeffrey S. Swayze , Omar J. Vakharia , Lauren S. Weaner , William Bruce Weisenburgh, II , Andrew M. Zwolinski
发明人： Daniel F. Dlugos, JR. , Chad P. Boudreaux , Robert P. Gill , Steven G. Hall , Christopher J. Hess , Jerome R. Morgan , Frederick E. Shelton, IV , Jeffrey S. Swayze , Omar J. Vakharia , Lauren S. Weaner , William Bruce Weisenburgh, II , Andrew M. Zwolinski
IPC分类号： A61B17/00
CPC分类号： A61F5/005 , A61F5/0086
摘要： An implantable restriction device includes a belt and a balloon secured to the belt for engagement with tissue when the implantable restriction device is positioned about the stomach. A spacer is associated with the belt for maintaining the restriction device in a spaced relation with a staple line employed during gastric reduction surgery.
摘要翻译：植入式限制装置包括带和固定到带上的球囊，当可植入的限制装置围绕胃定位时，与球体接合。间隔件与带相关联，用于将限制装置与胃减压手术期间使用的缝合线保持间隔开。

16. 发明授权

US09750629B2 Implantable restriction system tension release mechanism 有权
公开(公告)号：US09750629B2
公开(公告)日：2017-09-05
申请号：US12562267
申请日：2009-09-18
申请人： Daniel F. Dlugos, Jr. , Randal T. Byrum , Toralf Bork , Rocco Crivelli , Dean L. Garner , Alec J. Ginggen , Geoffrey C. Hueil , Donna L. Korvick , David T. Krumanaker , Amy L. Marcotte , Jeffrey D. Messerly , Kyle P. Moore , Daniel J. Mumaw , Anil K. Nalagatla , Mark S. Ortiz , Frederick E. Shelton, IV , Bret W. Smith , Jeffrey S. Swayze , Patrick J. Swindon , Richard W. Timm , Eric W. Thompson , Lauren S. Weaner
发明人： Daniel F. Dlugos, Jr. , Randal T. Byrum , Toralf Bork , Rocco Crivelli , Dean L. Garner , Alec J. Ginggen , Geoffrey C. Hueil , Donna L. Korvick , David T. Krumanaker , Amy L. Marcotte , Jeffrey D. Messerly , Kyle P. Moore , Daniel J. Mumaw , Anil K. Nalagatla , Mark S. Ortiz , Frederick E. Shelton, IV , Bret W. Smith , Jeffrey S. Swayze , Patrick J. Swindon , Richard W. Timm , Eric W. Thompson , Lauren S. Weaner
IPC分类号： A61B17/122 , A61F5/00 , A61F2/00
CPC分类号： A61F5/0053 , A61F2/0036 , A61F5/003 , A61F5/0056 , A61F5/0059
摘要： An apparatus for regulating the functioning of a patient's organ or duct includes an elongated member having a first end and a second end. A fastener is disposed on the first end of the elongated member. The fastener is configured to engage the second end of the elongated member so that the elongated member forms a loop around the organ or duct. A tension element is disposed for movement within the elongated member. A drive element is associated with and engages the tension element for causing the tension element to control the tension applied by the elongated member against a patient's body organ or duct. A tension release mechanism is associated with the tension element.

17. 发明申请

US20110071553A1 IMPLANTABLE RESTRICTION SYSTEM WITH LOAD MONITOR 有权
标题翻译：带有负载监控器的可植入式限制系统
公开(公告)号：US20110071553A1
公开(公告)日：2011-03-24
申请号：US12562257
申请日：2009-09-18
申请人： Daniel F. Dlugos, JR. , Wells D. Haberstich , Geoffrey C. Hueil , Donna L. Korvick , Jeffrey D. Messerly , Kyle P. Moore , Daniel J. Mumaw , Mark S. Ortiz , Frederick E. Shelton, IV , Patrick J. Swindon , Eric W. Thompson , Lauren S. Weaner
发明人： Daniel F. Dlugos, JR. , Wells D. Haberstich , Geoffrey C. Hueil , Donna L. Korvick , Jeffrey D. Messerly , Kyle P. Moore , Daniel J. Mumaw , Mark S. Ortiz , Frederick E. Shelton, IV , Patrick J. Swindon , Eric W. Thompson , Lauren S. Weaner
IPC分类号： A61B17/12 , G01L1/22 , G01L3/00
CPC分类号： A61F5/0059 , A61F2/0036 , A61F5/003 , A61F5/0056
摘要： An apparatus for regulating the functioning of a patient's organ or duct includes an elongated member having a first end and a second end. A fastener is disposed on the first end of the elongated member. The fastener is configured to engage the second end of the elongated member so that the elongated member forms a loop around the organ or duct. A tension element is disposed for movement within the elongated member. A drive element is associated with and engages the tension element for causing the tension element to control the tension applied by the elongated member against a patient's body organ or duct. A load monitor ensures that excessive pressure is not applied to a patient's body organ or duct.
摘要翻译：用于调节患者器官或管道的功能的装置包括具有第一端和第二端的细长构件。紧固件设置在细长构件的第一端上。紧固件构造成接合细长构件的第二端，使得细长构件围绕器官或管道形成环。张力元件设置成在细长构件内移动。驱动元件与张力元件相关联并与其接合，用于使张力元件控制由细长构件施加的抗张力抵靠患者身体器官或管道的张力。负载监视器确保不会对患者的身体器官或管道施加过大的压力。

18. 发明授权

US08523885B2 Implantable restriction system with load monitor 有权
标题翻译：带有负载监视器的可植入限制系统
公开(公告)号：US08523885B2
公开(公告)日：2013-09-03
申请号：US12562257
申请日：2009-09-18
申请人： Daniel F. Dlugos, Jr. , Wells D. Haberstich , Geoffrey C. Hueil , Donna L. Korvick , Jeffrey D. Messerly , Kyle P. Moore , Daniel J. Mumaw , Mark S. Ortiz , Frederick E. Shelton, IV , Patrick J. Swindon , Eric W. Thompson , Lauren S. Weaner
发明人： Daniel F. Dlugos, Jr. , Wells D. Haberstich , Geoffrey C. Hueil , Donna L. Korvick , Jeffrey D. Messerly , Kyle P. Moore , Daniel J. Mumaw , Mark S. Ortiz , Frederick E. Shelton, IV , Patrick J. Swindon , Eric W. Thompson , Lauren S. Weaner
IPC分类号： A61B17/12
CPC分类号： A61F5/0059 , A61F2/0036 , A61F5/003 , A61F5/0056
摘要： An apparatus for regulating the functioning of a patient's organ or duct includes an elongated member having a first end and a second end. A fastener is disposed on the first end of the elongated member. The fastener is configured to engage the second end of the elongated member so that the elongated member forms a loop around the organ or duct. A tension element is disposed for movement within the elongated member. A drive element is associated with and engages the tension element for causing the tension element to control the tension applied by the elongated member against a patient's body organ or duct. A load monitor ensures that excessive pressure is not applied to a patient's body organ or duct.
摘要翻译：用于调节患者器官或管道的功能的装置包括具有第一端和第二端的细长构件。紧固件设置在细长构件的第一端上。紧固件构造成接合细长构件的第二端，使得细长构件围绕器官或管道形成环。张力元件设置成在细长构件内移动。驱动元件与张力元件相关联并与其接合，用于使张力元件控制由细长构件施加的抗张力抵靠患者身体器官或管道的张力。负载监视器确保不会对患者的身体器官或管道施加过大的压力。

19. 发明申请

US20110071558A1 IMPLANTABLE RESTRICTION SYSTEM TENSION RELEASE MECHANISM 有权
标题翻译：可伸缩限制系统张力释放机制
公开(公告)号：US20110071558A1
公开(公告)日：2011-03-24
申请号：US12562267
申请日：2009-09-18
申请人： Daniel F. Dlugos, JR. , Randal T. Byrum , Toralf Bork , Rocco Crivelli , Dean L. Garner , Alec J. Ginggen , Geoffrey C. Hueil , Donna L. Korvick , David T. Krumanaker , Amy L. Marcotte , Jeffrey D. Messerly , Kyle P. Moore , Daniel J. Mumaw , Anil K. Nalagatla , Mark S. Ortiz , Frederick E. Shelton, IV , Bret W. Smith , Jeffrey S. Swayze , Patrick J. Swindon , Richard W. Timm , Eric W. Thompson , Lauren S. Weaner
发明人： Daniel F. Dlugos, JR. , Randal T. Byrum , Toralf Bork , Rocco Crivelli , Dean L. Garner , Alec J. Ginggen , Geoffrey C. Hueil , Donna L. Korvick , David T. Krumanaker , Amy L. Marcotte , Jeffrey D. Messerly , Kyle P. Moore , Daniel J. Mumaw , Anil K. Nalagatla , Mark S. Ortiz , Frederick E. Shelton, IV , Bret W. Smith , Jeffrey S. Swayze , Patrick J. Swindon , Richard W. Timm , Eric W. Thompson , Lauren S. Weaner
IPC分类号： A61B17/122 , A61F2/04
CPC分类号： A61F5/0053 , A61F2/0036 , A61F5/003 , A61F5/0056 , A61F5/0059
摘要： An apparatus for regulating the functioning of a patient's organ or duct includes an elongated member having a first end and a second end. A fastener is disposed on the first end of the elongated member. The fastener is configured to engage the second end of the elongated member so that the elongated member forms a loop around the organ or duct. A tension element is disposed for movement within the elongated member. A drive element is associated with and engages the tension element for causing the tension element to control the tension applied by the elongated member against a patient's body organ or duct. A tension release mechanism is associated with the tension element.
摘要翻译：用于调节患者器官或管道的功能的装置包括具有第一端和第二端的细长构件。紧固件设置在细长构件的第一端上。紧固件构造成接合细长构件的第二端，使得细长构件围绕器官或管道形成环。张力元件设置成在细长构件内移动。驱动元件与张力元件相关联并与其接合，用于使张力元件控制由细长构件施加的抗张力抵靠患者身体器官或管道的张力。张力释放机构与张力元件相关联。

20. 发明申请

US20110040313A1 IMPLANTABLE RESTRICTION DEVICE WITH PROTECTIVE MEMBER 审中-公开
标题翻译：具有保护构件的可植入限制装置
公开(公告)号：US20110040313A1
公开(公告)日：2011-02-17
申请号：US12541630
申请日：2009-08-14
申请人： Daniel F. Dlugos, JR. , Steven G. Hall , David T. Krumanaker , Brandon J. Lloyd , Amy L. Marcotte , Jerome R. Morgan , Mark S. Ortiz , David N. Plescia , Frederick E. Shelton, IV , Jeffrey S. Swayze , Richard W. Timm , Lauren S. Weaner , Duane A. Granston
发明人： Daniel F. Dlugos, JR. , Steven G. Hall , David T. Krumanaker , Brandon J. Lloyd , Amy L. Marcotte , Jerome R. Morgan , Mark S. Ortiz , David N. Plescia , Frederick E. Shelton, IV , Jeffrey S. Swayze , Richard W. Timm , Lauren S. Weaner , Duane A. Granston
IPC分类号： A61B17/12
CPC分类号： A61F5/0056 , A61F5/003
摘要： An implantable restriction device includes a belt and a balloon secured to the belt for engagement with tissue when the implantable restriction device is positioned about an organ. A protective member is associated with the balloon for positioning between the balloon and a tissue surface defining a band tissue interface.
摘要翻译：植入式限制装置包括带和固定到带上的球囊，当可植入式限制装置围绕器官定位时，与球体接合。保护构件与球囊相关联，用于在球囊和限定带组织界面的组织表面之间进行定位。

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