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11. 发明授权

US07961983B2 Generating gigapixel images 有权
标题翻译：生成千兆像素图像
公开(公告)号：US07961983B2
公开(公告)日：2011-06-14
申请号：US11779871
申请日：2007-07-18
申请人： Matthew Uyttendaele , Michael Cohen
发明人： Matthew Uyttendaele , Michael Cohen
IPC分类号： G06K9/00 , G06K9/36 , G06K9/32
CPC分类号： G06T3/4038
摘要： A gigapixel image is generated from a set of images in raw format depicting different portions of a panoramic scene that has up to a full spherical field of view. Radiometric alignment of the images creates a set of images in radiance format. Geometric alignment of the radiance format images creates a set of true poses for the images in radiance format. A gigapixel image depicting the entire scene is assembled from the set of radiance format images and radiance format true poses for the images. The set of images in raw format is captured using a conventional digital camera, equipped with a telephoto lens, attached to a motorized head. The head is programmed to pan and tilt the camera in prescribed increments to individually capture the images at a plurality of exposures and with a prescribed overlap between images depicting adjacent portions of the scene.
摘要翻译：从原始格式的一组图像生成一个千兆像素图，描绘具有全球面视野的全景场景的不同部分。图像的放射线对准会以辐射格式创建一组图像。辐射格式图像的几何对齐为辐射格式的图像创建一组真实姿势。描绘整个场景的百万像素图像是由一组辐射格式图像和辐射格式组合而成的图像的真实姿势。原始格式的图像集是使用配有远摄镜头的常规数码相机来捕捉的，该长焦镜头连接到电动头部。头被编程为以规定的增量平移和倾斜相机，以单独地以多次曝光并且以描绘场景的相邻部分的图像之间的规定的重叠来捕获图像。

12. 发明授权

US07729256B2 Correlating packets 有权
标题翻译：关联数据包
公开(公告)号：US07729256B2
公开(公告)日：2010-06-01
申请号：US11180879
申请日：2005-07-13
申请人： Patrick J. Malloy , Michael Cohen , Alain J. Cohen
发明人： Patrick J. Malloy , Michael Cohen , Alain J. Cohen
IPC分类号： G01R31/08 , G06F15/173
CPC分类号： H04L63/0236 , H04L1/18 , H04L63/1416 , H04L2012/565
摘要： A system/method searches a traffic stream for a sequence of “matching” packets that exhibit a high degree of correlation or similarity to a sequence of “reference” packets. The correlation between matching and reference packets is based on a degree of correspondence between individual packets, as well as the sequence-order of the corresponding packets. A variation of the Needleman-Wunsch algorithm is preferably used to select corresponding packets in the traffic stream that provide a sequence-order that best matches the sequence-order of the reference packets, based on a measure of the correspondence for each match, and a penalty associated with each non-match. The algorithm is further modified to reduce the required search-space for finding corresponding packets in the traffic stream.
摘要翻译：系统/方法在业务流中搜索与“参考”分组的序列呈现高度相关性或相似性的“匹配”分组序列。匹配和参考分组之间的相关性基于各个分组之间的对应程度以及相应分组的顺序。 Needleman-Wunsch算法的变体优选地用于基于每个匹配的对应度的度量来选择提供与参考分组的序列顺序最佳匹配的序列顺序的业务流中的相应分组，以及与每个不匹配相关的罚款。该算法被进一步修改以减少用于在流量流中找到相应分组的所需搜索空间。

13. 发明授权

US07687506B2 Selective serine/threonine kinase inhibitors 有权
标题翻译：选择性丝氨酸/苏氨酸激酶抑制剂
公开(公告)号：US07687506B2
公开(公告)日：2010-03-30
申请号：US10552847
申请日：2004-04-12
申请人： Jack Taunton , Michael Cohen , Kevan Shokat , Chao Zhang
发明人： Jack Taunton , Michael Cohen , Kevan Shokat , Chao Zhang
IPC分类号： C07D487/04 , A61K31/52
CPC分类号： C07D487/04
摘要： Inhibition of protein kinases having one or more cysteine residues within the ATP binding site is effected by contacting the kinase, per se or in a cell or subject, with an inhibitory-effective amount of a compound having a heterocyclic core structure comprised of two or more fused rings containing at least one nitrogen ring atom, and an electrophilic substituent that is capable of reacting with a cysteine residue within the ATP binding site of a kinase. Preferred compounds include certain pyrrolopyrimidines and oxindoles having such an electrophilic substituent and optionally an aromatic or heteroaromatic substituent that is capable of interacting with a threonine or smaller residue located in the gatekeeper position of the kinase. Kinases lacking such cysteine residues may be engineered or modified so that they are capable of being inhibited by such compounds by replacing a valine or other amino acid residue within the ATP binding site by a cysteine residue.
摘要翻译：在ATP结合位点内具有一个或多个半胱氨酸残基的蛋白激酶的抑制通过使本身或细胞或受试者中的激酶与抑制有效量的具有由两个或更多个的杂环核心结构组成的化合物接触来实现含有至少一个氮环原子的稠环，以及能够与激酶的ATP结合位点内的半胱氨酸残基反应的亲电取代基。优选的化合物包括具有这样的亲电子取代基的某些吡咯并嘧啶和羟吲哚，以及任选的能够与位于激酶的关守位置的苏氨酸或更小残基相互作用的芳族或杂芳族取代基。缺乏这种半胱氨酸残基的激酶可以被改造或修饰，使得它们能够被这样的化合物抑制，通过用半胱氨酸残基替换ATP结合位点内的缬氨酸或其它氨基酸残基。

14. 发明申请

US20100075417A1 Methods and devices for isolating embryonic stem cells 审中-公开
标题翻译：用于分离胚胎干细胞的方法和装置
公开(公告)号：US20100075417A1
公开(公告)日：2010-03-25
申请号：US12454263
申请日：2009-05-14
申请人： Michael Cohen , Xiangcan Zhan , Michael J. Shamblott
发明人： Michael Cohen , Xiangcan Zhan , Michael J. Shamblott
IPC分类号： C12N5/0735 , C12M1/12
CPC分类号： C12N5/0606
摘要： Methods, devices and kits are provided for isolating or enriching multicellular embryonic stem (ES) cell colonies from a mixture of multicellular ES cell colonies and single ES cells present in a cellular suspension, by utilizing a filtration matrix that selectively excludes passage of multicellular ES cell colonies. Isolated or enriched multicellular ES cell colonies can be used for propagating pluripotent ES cells.
摘要翻译：提供了方法，装置和试剂盒，用于通过使用选择性排除多细胞ES细胞通过的过滤基质从多细胞ES细胞集落和存在于细胞悬液中的单个ES细胞的混合物中分离或富集多细胞胚胎干细胞集落群落。分离或富集的多细胞ES细胞集落可用于繁殖多能ES细胞。

15. 发明授权

US07483553B2 Caricature exaggeration 有权
标题翻译：漫画夸张
公开(公告)号：US07483553B2
公开(公告)日：2009-01-27
申请号：US10812754
申请日：2004-03-29
申请人： Ying-Qing Xu , Heung-Yeung Shum , Michael Cohen , Lin Liang , Hua Zhong
发明人： Ying-Qing Xu , Heung-Yeung Shum , Michael Cohen , Lin Liang , Hua Zhong
IPC分类号： G06K9/00
CPC分类号： G06T11/00
摘要： Caricature exaggeration systems, engines, and methods create a drawing of a facial image, compare relationships among facial features in the drawing to corresponding relationships in facial images and corresponding caricatures in a database, and automatically exaggerate at least one relationship among facial features in the drawing based on the facial images and the corresponding caricatures in the database.
摘要翻译：漫画夸张系统，引擎和方法创建面部图像的图形，比较绘图中的面部特征与面部图像中的对应关系和数据库中相应漫画的关系，并自动夸大图中面部特征之间的至少一个关系基于面部图像和数据库中的相应漫画。

16. 发明申请

US20080233087A1 Methods for identifying, isolating, and utilizing endocrine progenitor cells from adult human pancreata 审中-公开
标题翻译：从成年人胰腺鉴定，分离和利用内分泌祖细胞的方法
公开(公告)号：US20080233087A1
公开(公告)日：2008-09-25
申请号：US11980797
申请日：2007-10-31
申请人： Michael J. Shamblott , Michael Cohen
发明人： Michael J. Shamblott , Michael Cohen
IPC分类号： A61K35/12 , G01N33/569 , C12M1/00 , A61P3/10 , C12N5/06
CPC分类号： G01N33/56966 , C12N5/0678 , G01N2333/70596 , G01N2400/02 , G01N2800/042
摘要： The presence of the cell surface marker CD133 or the presence of a glycosylated form of the prominin-1 gene product on adult pancreatic cells is used to identify pancreatic endocrine progenitor cells, and useful in methods of isolation and enrichment. Isolated pancreatic endocrine progenitor cells can be used for cell based therapy for insulin-dependent diabetes and pancreatectomy patients.
摘要翻译：使用细胞表面标志物CD133的存在或成年胰腺细胞上存在的糖基化形式的表位蛋白-1基因产物用于鉴定胰腺内分泌祖细胞，并且可用于分离和富集的方法。分离的胰腺内分泌祖细胞可用于胰岛素依赖性糖尿病和胰腺切除术患者的基于细胞的治疗。

17. 发明申请

US20070206878A1 SYSTEM AND METHOD FOR HEAD SIZE EQUALIZATION IN 360 DEGREE PANORAMIC IMAGES 有权
标题翻译：用于360度全景图像中的大小均匀化的系统和方法
公开(公告)号：US20070206878A1
公开(公告)日：2007-09-06
申请号：US11465703
申请日：2006-08-18
申请人： Zicheng Liu , Ross Cutler , Michael Cohen , Zhengyou Zhang
发明人： Zicheng Liu , Ross Cutler , Michael Cohen , Zhengyou Zhang
IPC分类号： G06K9/36
CPC分类号： G06T3/0062 , G06K9/00228 , G06T3/4038 , G06T5/006 , G06T7/30
摘要： A real-time approximately 360 degree image correction system and a method for alleviating distortion and perception problems in images captured by omni-directional cameras. In general, the real-time panoramic image correction method generates a warp table from pixel coordinates of a panoramic image and applies the warp table to the panoramic image to create a corrected panoramic image. The corrections are performed using a parametric class of warping functions that include Spatially Varying Uniform (SVU) scaling functions. The SVU scaling functions and scaling factors are used to perform vertical scaling and horizontal scaling on the panoramic image pixel coordinates. A horizontal distortion correction is performed using the SVU scaling functions at at least two different scaling factors. This processing generates a warp table that can be applied to the panoramic image to yield the corrected panoramic image. In one embodiment the warp table is concatenated with a stitching table used to create the panoramic image.
摘要翻译：一种实时大约360度的图像校正系统和一种减轻全方位摄像机拍摄图像失真和感知问题的方法。通常，实时全景图像校正方法从全景图像的像素坐标生成扭曲表，并将经线表应用于全景图像，以创建校正的全景图像。校正使用包括空间变化均匀（SVU）缩放函数的参数化的翘曲函数类来执行。 SVU缩放函数和缩放因子用于对全景图像像素坐标执行垂直缩放和水平缩放。使用SVU缩放函数以至少两个不同的缩放因子执行水平失真校正。该处理产生可应用于全景图像以产生经校正的全景图像的经向表。在一个实施例中，经线台与用于创建全景图像的缝合台连接。

18. 发明申请

US20070189627A1 Automated face enhancement 有权
标题翻译：自动脸部增强
公开(公告)号：US20070189627A1
公开(公告)日：2007-08-16
申请号：US11353799
申请日：2006-02-14
申请人： Michael Cohen , Jue Wang
发明人： Michael Cohen , Jue Wang
IPC分类号： G06K9/40 , G06K9/00
CPC分类号： G06K9/00228
摘要： An automated face enhancement system and process which can automatically improve faces in videos or other images by applying cosmetic effects, given only a small amount of user interaction for initialization. For an input video, the system will first track the face and eye locations, and classify pixels in the face into different facial components based on local color models. The classification results of different frames are temporally smoothed to ensure temporal coherence. A set of cosmetic filters are then applied to different facial components.
摘要翻译：一种自动化的面部增强系统和过程，可以通过应用美容效果来自动改善视频或其他图像中的脸部，只给予少量用户交互进行初始化。对于输入视频，系统将首先跟踪脸部和眼睛的位置，并根据本地颜色模型将脸部像素分类为不同的面部组件。不同帧的分类结果在时间上平滑，以确保时间一致性。然后将一套美容过滤器应用于不同的面部组件。

19. 发明申请

US20070076016A1 Photographing big things 有权
标题翻译：拍摄大件事情
公开(公告)号：US20070076016A1
公开(公告)日：2007-04-05
申请号：US11323241
申请日：2005-12-30
申请人： Aseem Agarwala , Maneesh Agrawala , Michael Cohen , David Salesin , Richard Szeliski
发明人： Aseem Agarwala , Maneesh Agrawala , Michael Cohen , David Salesin , Richard Szeliski
IPC分类号： G09G5/00
CPC分类号： G06T3/4038 , Y10S707/99933
摘要： The claimed subject matter can provide an architecture that facilitates producing a single image that can visualize a scene too large to depict from any single perspective view. These images can be stitched together on a 2-dimensional picture surface to form a multi-perspective image of the entire extent of the scene depicted by the input images. Where the respective images overlap, an objective function can be employed to determine where to make a transition between one image and the next. The objective function can employ a data cost and a seam cost to make this determination.
摘要翻译：所要求保护的主题可以提供便于产生可以使场景过大可视化的单个图像的架构，从而不能从任何单个透视图描绘。这些图像可以在二维图像表面上缝合在一起以形成由输入图像描绘的场景的整个范围的多视角图像。在各个图像重叠的地方，可以采用目标函数来确定在一个图像和下一个图像之间进行转换的位置。目标函数可以采用数据成本和接缝成本来做出这一决定。

20. 发明申请

US20070028757A1 Composite armor plate and ceramic bodies for use therein 审中-公开
标题翻译：复合铠装板和陶瓷体用于其中
公开(公告)号：US20070028757A1
公开(公告)日：2007-02-08
申请号：US11187550
申请日：2005-07-22
申请人： Michael Cohen
发明人： Michael Cohen
IPC分类号： F41H5/02
CPC分类号： F41H5/0414 , F41H5/0492
摘要： The invention provides a composite armor plate for absorbing and dissipating kinetic energy from high-velocity projectiles, the plate comprising a single internal layer of pellets which are bound and retained in plate form by an elastic material, substantially internally within the elastic material, such that the pellets are bound in a plurality of spaced-apart rows and columns, the pellets being made of ceramic material, and the pellets being substantially fully embedded in the elastic material so that the pellets form an internal layer, wherein the solidified material and the plate are elastic, and wherein a majority of each of the pellets is in direct contact with six adjacent pellets in the same layer to provide mutual lateral confinement therebetween, each of the pellets being characterized by a body having a substantially regular geometric cross-sectional area and first and second end faces, each of the end faces projecting from the body and having an outwardly decreasing cross-sectional area wherein the height of the end face disposed substantially opposite to an outer impact receiving major surface of the plate is less than 15% of the length of the diameter of the pellet body from which it projects.
摘要翻译：本发明提供了一种用于从高速弹丸吸收和耗散动能的复合装甲板，该板包括单个的内部颗粒，其内部基本上在弹性材料内部以弹性材料结合并保持为板状，使得颗粒以多个间隔开的行和列结合，颗粒由陶瓷材料制成，并且颗粒基本上完全嵌入弹性材料中，使得颗粒形成内层，其中固化材料和板并且其中大部分颗粒与相同层中的六个相邻颗粒直接接触以在其间提供相互的侧向约束，每个颗粒的特征在于具有基本上规则的几何横截面积的主体，以及第一和第二端面，每个端面从主体突出并且具有向外减小的交叉其特征在于，与所述板的外部冲击接收主表面大致相对的端面的高度小于其从其突出的球团体直径的长度的15％。

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