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11. 发明授权

US4865848A Skin permeation enhancer compositions using sucrose esters 失效
标题翻译：使用蔗糖酯的皮肤渗透促进剂组合物
公开(公告)号：US4865848A
公开(公告)日：1989-09-12
申请号：US19442
申请日：1987-02-26
申请人： Yu-Ling Cheng , Robert M. Gale , Edna Sugihara , Harold F. Sanders
发明人： Yu-Ling Cheng , Robert M. Gale , Edna Sugihara , Harold F. Sanders
IPC分类号： A61K9/70 , A61K47/00 , A61K47/26
CPC分类号： A61K9/7053 , A61K47/26 , A61K9/7076 , A61K9/7084
摘要： A method for enhancing the transdermal flux of a transdermally deliverable drug through intact skin is described in which the drug is delivered simultaneously with sucrose monolaurate or a mixture of sucrose esters of coconut fatty acids, which is predominantly sucrose monolaurate. Preferred embodiments of therapeutic systems for delivering the drug and the sucrose ester employ a matrix containing drug at a concentration above saturation.

12. 发明授权

US4820720A Transdermal drug composition with dual permeation enhancers 失效
标题翻译：具有双重渗透促进剂的透皮药物组合物
公开(公告)号：US4820720A
公开(公告)日：1989-04-11
申请号：US174932
申请日：1988-03-29
申请人： Harold F. Sanders , Yu-Ling Cheng , David J. Enscore , Shari B. Libicki
发明人： Harold F. Sanders , Yu-Ling Cheng , David J. Enscore , Shari B. Libicki
IPC分类号： A61K9/00 , A61K9/70 , A61K47/10 , A61K47/14 , A61K31/44
CPC分类号： A61K9/7053 , A61K47/10 , A61K47/14 , A61K9/0014 , A61K9/7084 , Y10S514/946 , Y10S514/947
摘要： A dosage form that coadministers a drug and two percutaneous absorption enhancers to a defined area of the skin is described. The dosage form comprises a body that contains supplies of drug and enhancers and has a basal surface that contacts the area of skin and transmits the drug and enhancers to the area for absorption thereby.
摘要翻译：描述了将药物和两个经皮吸收促进剂组合到皮肤的限定区域的剂型。剂型包括含有药物和增强剂供应的身体，并且具有接触皮肤区域的基底表面并将药物和增强剂传递到所述吸收区域。

13. 发明授权

US4764379A Transdermal drug delivery device with dual permeation enhancers 失效
标题翻译：具有双重渗透促进剂的透皮药物递送装置
公开(公告)号：US4764379A
公开(公告)日：1988-08-16
申请号：US88767
申请日：1987-08-24
申请人： Harold F. Sanders , Yu-Ling Cheng , David J. Enscore , Shari B. Libicki
发明人： Harold F. Sanders , Yu-Ling Cheng , David J. Enscore , Shari B. Libicki
IPC分类号： A61K9/00 , A61K9/70 , A61K47/10 , A61K47/14 , A61K47/26 , A61F13/00
CPC分类号： A61K9/7084 , A61K47/10 , A61K47/14 , A61K9/0014 , Y10S514/946 , Y10S514/947
摘要： A dosage form that coadministers a drug and two percutaneous adsorption enhancers to a defined area of the skin is described. The dosage form comprises a body that contains supplies of drug and enhancers and has a basal surface that contacts the area of skin and transmits the drug and enhancers to the area for absorption thereby.

14. 发明申请

US20210139356A1 TREATMENT OF FECAL MATTER BY SMOLDERING AND CATALYSIS 有权
公开(公告)号：US20210139356A1
公开(公告)日：2021-05-13
申请号：US16318050
申请日：2017-07-17
申请人： Yu-Ling Cheng
发明人： Yu-Ling Cheng , Shadi Saberi , Aaron Fernandes
IPC分类号： C02F1/72 , C02F11/10 , C01B32/50 , C01B5/00 , B01J23/42
摘要： Described are methods and devices for the treatment of fecal matter. A column reactor is used to smolder fecal matter to produce and a volatile components stream and smoldered media. The volatile components stream may be subject to catalysis to reduce the emission of noxious substances and/or generate heat energy. Also described is the use of a turntable for removing smoldered media from the column reactor.

15. 发明授权

US08724842B2 Universal angle loudspeaker bracket 有权
标题翻译：通用角度扬声器支架
公开(公告)号：US08724842B2
公开(公告)日：2014-05-13
申请号：US13425745
申请日：2012-03-21
申请人： Yoichiro Sumitani , Chun-Yi Lin , Yu-Ling Cheng , Chih-Huang Hsiao
发明人： Yoichiro Sumitani , Chun-Yi Lin , Yu-Ling Cheng , Chih-Huang Hsiao
IPC分类号： H04R1/02
CPC分类号： H04R1/026 , H04R1/021 , H04R1/32
摘要： An apparatus for mounting a loudspeaker unit to a structure is disclosed. A primary mounting bracket is defined by an arcuate center section and a pair of opposed arms extending therefrom. There is at least one open groove and at least one substantially coextensive track spanning the arcuate center section. Each of the arms include a circular planar bearing structure rotatably engageable to a corresponding one of bracket coupling platforms on an enclosure of the loudspeaker unit. A tab defining at least one mounting hardware hole in axial alignment with open groove substantially throughout its length is in a guided sliding engagement with the track. The enclosure of the loudspeaker unit is rotatable about a first axis extending between the arms of the primary mounting bracket and about a second axis defined by a radial center of an arc corresponding to a travel path of the tab along the track.
摘要翻译：公开了一种用于将扬声器单元安装到结构的装置。主安装支架由弧形中心部分和从其延伸的一对相对臂限定。至少有一个开槽和跨过弧形中心部分的至少一个基本上共同延伸的轨迹。每个臂包括可旋转地接合到扬声器单元的外壳上的对应的一个支架联接平台的圆形平面轴承结构。基本上整个其长度上限定至少一个与开放槽轴向对准的安装硬件孔的突片处于与轨道的引导滑动接合中。扬声器单元的外壳可围绕在主安装支架的臂之间延伸的第一轴线旋转，并且围绕第二轴线旋转，该第二轴线由对应于突片沿着轨道的行进路径的弧的径向中心限定。

16. 发明申请

US20130251187A1 UNIVERSAL ANGLE LOUDSPEAKER BRACKET 有权
标题翻译：通用角度扬声器支架
公开(公告)号：US20130251187A1
公开(公告)日：2013-09-26
申请号：US13425745
申请日：2012-03-21
申请人： Yoichiro Sumitani , Chun-Yi Lin , Yu-Ling Cheng , Chih-Huang Hsiao
发明人： Yoichiro Sumitani , Chun-Yi Lin , Yu-Ling Cheng , Chih-Huang Hsiao
IPC分类号： H04R1/02
CPC分类号： H04R1/026 , H04R1/021 , H04R1/32
摘要： An apparatus for mounting a loudspeaker unit to a structure is disclosed. A primary mounting bracket is defined by an arcuate center section and a pair of opposed arms extending therefrom. There is at least one open groove and at least one substantially coextensive track spanning the arcuate center section. Each of the arms include a circular planar bearing structure rotatably engageable to a corresponding one of bracket coupling platforms on an enclosure of the loudspeaker unit. A tab defining at least one mounting hardware hole in axial alignment with open groove substantially throughout its length is in a guided sliding engagement with the track. The enclosure of the loudspeaker unit is rotatable about a first axis extending between the arms of the primary mounting bracket and about a second axis defined by a radial center of an arc corresponding to a travel path of the tab along the track.
摘要翻译：公开了一种用于将扬声器单元安装到结构的装置。主安装支架由弧形中心部分和从其延伸的一对相对臂限定。至少有一个开槽和跨过弧形中心部分的至少一个基本上共同延伸的轨迹。每个臂包括可旋转地接合到扬声器单元的外壳上的对应的一个支架联接平台的圆形平面轴承结构。基本上整个其长度上限定至少一个与开放槽轴向对准的安装硬件孔的突片处于与轨道的引导滑动接合中。扬声器单元的外壳可围绕在主安装支架的臂之间延伸的第一轴线旋转，并且围绕第二轴线旋转，该第二轴线由对应于突片沿着轨道的行进路径的弧的径向中心限定。

17. 发明授权

US07193007B2 Environment responsive gelling copolymer 失效
标题翻译：环境响应胶凝共聚物
公开(公告)号：US07193007B2
公开(公告)日：2007-03-20
申请号：US10221084
申请日：2001-03-15
申请人： Yu-Ling Cheng , Hai-Hui Lin
发明人： Yu-Ling Cheng , Hai-Hui Lin
IPC分类号： C08F290/04 , C08L53/00
CPC分类号： C08L53/00 , A61L27/16 , A61L27/52 , C08F293/00 , C08F297/00 , Y10S524/916
摘要： The invention relates to a gelable copolymer composition comprising a copolymer in a solvent. The copolymer has the structure A(B)n, wherein the core (A) is soluble in the solvent, the arms (B) are convertible between soluble and insoluble in the solent depending on an environmental condition, and n>1. The composition forms a gel under environmental conditions in which B is insoluble, through formation of B aggregates. Block copolymers comprising polyethylene glycol (PEG) and poly(N-iso-propylacrylamide) (PNIPAAm) having a liquid form at ambient temperature under aqueous conditions and a gel form at body temperature are disclosed. Copolymer compositions according to the invention can be used to form in situ implants useful in slow-release formulations of biologically active molecules
摘要翻译：本发明涉及在溶剂中包含共聚物的可胶凝共聚物组合物。共聚物具有结构A（B）n，其中核（A）可溶于溶剂，臂（B）可根据环境条件在可溶性和不溶性之间转化，并且n> 1。组合物通过形成B聚集体在环境条件下形成凝胶，其中B不溶。公开了包含聚乙二醇（PEG）和聚环氧乙烷（PNIPAAm）在环境温度和水温条件下具有液态的嵌段共聚物和体温下的凝胶形式。根据本发明的共聚物组合物可用于形成用于生物活性分子的缓释制剂的原位植入物

18. 发明申请

US20050020719A1 Environment responsive gelling copolymer 失效
标题翻译：环境响应胶凝共聚物
公开(公告)号：US20050020719A1
公开(公告)日：2005-01-27
申请号：US10221084
申请日：2001-03-15
申请人： Yu-Ling Cheng , Hai-Hui Lin
发明人： Yu-Ling Cheng , Hai-Hui Lin
IPC分类号： A61L27/16 , A61L27/52 , C08F293/00 , C08F297/00 , C08L53/00 , C08K3/00 , A61F2/00 , C08F20/54 , C08L1/00
CPC分类号： C08L53/00 , A61L27/16 , A61L27/52 , C08F293/00 , C08F297/00 , Y10S524/916
摘要： The invention relates to a gelable copolymer composition comprising a copolymer in a solvent. The copolymer has the structure A(B)n, wherein the core (A) is soluble in the solvent, the arms (B) are convertible between soluble and insoluble in the solent depending on an environmental condition, and n>1. The composition forms a gel under environmental conditions in which B is insoluble, through formation of B aggregates. Block copolymers comprising polyethylene glycol (PEG) and poly(N-iso-propylacrylamide) (PNIPAAm) having a liquid form at ambient temperature under aqueous conditions and a gel form at body temperature are disclosed. Copolymer compositions according to the invention can be used to form in situ implants useful in slow-release formulations of biologically active molecules.
摘要翻译：本发明涉及在溶剂中包含共聚物的可胶凝共聚物组合物。共聚物具有结构A（B）n，其中核（A）可溶于溶剂，臂（B）可根据环境条件在可溶性和不溶性之间转化，并且n> 1。组合物通过形成B聚集体在环境条件下形成凝胶，其中B不溶。公开了包含聚乙二醇（PEG）和聚环氧乙烷（PNIPAAm）在环境温度和水温条件下具有液态的嵌段共聚物和体温下的凝胶形式。根据本发明的共聚物组合物可用于形成用于生物活性分子的缓释制剂的原位植入物。

19. 发明授权

US4153430A Process and apparatuses for contacting a gas phase and a liquid phase 失效
标题翻译：用于接触气相和液相的方法和装置
公开(公告)号：US4153430A
公开(公告)日：1979-05-08
申请号：US694464
申请日：1976-06-09
申请人： Chen-Yen Cheng , Yu-Ling Cheng , Wu-Cheng Cheng
发明人： Chen-Yen Cheng , Yu-Ling Cheng , Wu-Cheng Cheng
IPC分类号： B01D47/00 , B01D53/18
CPC分类号： B01D47/00 , B01D53/18
摘要： This invention introduces a process and apparatuses for bringing a gas phase into contact with a liquid phase for an extended period of time and subjecting the phases to appropriate motions so as to accomplish efficient absorption and desorption operations and efficient pressurization and depressurization operations. The process is conducted in a processing system that comprises of many small compartments and a moving mechanism to which the compartments are attached. Each compartment has a confining wall to contain a mass of the feed gas and has an opening through which a liquid may be brought in contact with the gas to provide a gas-liquid interface. The processing system is submerged in the liquid phase and is divided into a first zone and a second zone; the compartments in the two zones are respectively subjected to a downward movement and an upward movement. The net force (buoyancy - gravity) that each zone of the system is subjected to is reduced by properly adjusting the amount of gas introduced in each compartment, distributing the masses of the confining walls of the compartments and the moving mechanism and by purposely adding weights and distributing the added weights. The upward motion and the downward motion of the two zones are coupled together through the moving mechanism so that the net forces applied to the two zones are balanced against each other. Thus, the two motions help each other to cut down the work input needed in the process.
摘要翻译：本发明引入了一种用于使气相与液相接触较长时间的方法和装置，并使相适当的运动进行，以便实现有效的吸收和解吸操作以及有效的加压和减压操作。该过程在包括许多小隔室和移动机构的处理系统中进行，隔室连接到该移动机构。每个隔间具有一个限制壁，以容纳一定量的进料气体，并具有一个开口，液体可以通过该开口与气体接触以提供气 - 液界面。处理系统浸没在液相中，分为第一区和第二区; 两个区域中的隔室分别经受向下运动和向上运动。通过适当地调整每个隔室中引入的气体量，分配隔室的限制壁和移动机构的质量，并通过有意添加重量来减少系统每个区域受到的净力（浮力 - 重力）并分配加权。两个区域的向上运动和向下运动通过移动机构联接在一起，使得施加到两个区域的净力相互平衡。因此，这两个动议有助于减少此过程中所需的工作投入。

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