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11. 发明申请

US20110060362A1 DEVICES AND METHODS FOR TREATING RECTOVAGINAL AND OTHER FISTULAE 审中-公开
标题翻译：用于治疗重建和其他造影剂的装置和方法
公开(公告)号：US20110060362A1
公开(公告)日：2011-03-10
申请号：US12948177
申请日：2010-11-17
申请人： Umesh H. Patel , F. Joseph Obermiller
发明人： Umesh H. Patel , F. Joseph Obermiller
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00641
摘要： Provided by certain aspects of the invention are methods for treating fistulae and various fistula graft assemblages useful in this regard. Illustratively, some inventive methods are useful in treating fistulae having at least a first fistula opening, a second fistula opening and a fistula tract extending therebetween. In one step, a first capping member is positioned over the first fistula opening such that a first pulling member, which extends from the first capping member, passes through the fistula tract. In another step, a second capping member is positioned over the second fistula opening such that a second pulling member, which extends from the second capping member, passes through the fistula tract. A first pulling force is applied to the first pulling member, and a second pulling force is applied to the second pulling member, for maintaining the first capping member over the first fistula opening and for maintaining the second capping member over the second fistula opening, respectively.
摘要翻译：由本发明的某些方面提供的是用于治疗瘘管和各种瘘移植物组合物的方法。说明性地，一些本发明的方法可用于治疗具有至少第一瘘开口，第二瘘开口和在其间延伸的瘘管道的瘘。在一个步骤中，第一封盖构件定位在第一瘘开口上方，使得从第一封盖构件延伸的第一牵引构件穿过瘘管道。在另一步骤中，第二封盖构件定位在第二瘘开口上方，使得从第二封盖构件延伸的第二牵引构件穿过瘘管道。第一拉力被施加到第一牵引构件，并且第二拉力施加到第二牵引构件，用于将第一封盖构件保持在第一瘘开口上方并且用于将第二封盖构件分别保持在第二瘘开口上方。

12. 发明申请

US20110046576A1 TISSUE AUGMENTATION DEVICES AND METHODS 有权
标题翻译：组织补充装置及方法
公开(公告)号：US20110046576A1
公开(公告)日：2011-02-24
申请号：US12939636
申请日：2010-11-04
申请人： Umesh H. Patel , F. Joseph Obermiller , Bhavin Shah , Chad E. Johnson
发明人： Umesh H. Patel , F. Joseph Obermiller , Bhavin Shah , Chad E. Johnson
IPC分类号： A61M5/00
CPC分类号： A61F2/0059
摘要： Tissue augmentation devices, as well as methods of manufacturing and using the same, are disclosed. In certain embodiments, a tissue augmentation device comprises an elongate tissue penetrating member and an amount of remodelable material, wherein at least a portion of the elongate member is cannulated, and at least a portion of the amount of material is received within at least a portion of the cannulated portion of the elongate member. The elongate tissue penetrating member may provide at least one deformation that is configured to constrict portions of the amount of remodelable material received within the elongate member. In alternate embodiments, a flexible covering over an implantable biomaterial provides protection and allows an easier delivery of the biomaterial to a tissue tract.
摘要翻译：公开了组织增加装置，以及制造和使用它们的方法。在某些实施例中，组织增强装置包括细长的组织穿透构件和一定量的可重塑材料，其中细长构件的至少一部分被插管，并且至少部分材料量被容纳在至少一部分内的细长构件的插管部分。细长组织穿透构件可以提供至少一个变形，其被构造成收缩在细长构件内容纳的可重塑材料的量的部分。在替代实施例中，可植入生物材料上的柔性覆盖物提供保护并且允许将生物材料更容易地递送到组织道。

13. 发明授权

US07897167B2 Implantable graft to close a fistula 有权
标题翻译：植入式移植物闭合瘘管
公开(公告)号：US07897167B2
公开(公告)日：2011-03-01
申请号：US11472642
申请日：2006-06-21
申请人： David N. Armstrong , Brian L. Bates , Mark W. Bleyer , F. Joseph Obermiller , Umesh H. Patel
发明人： David N. Armstrong , Brian L. Bates , Mark W. Bleyer , F. Joseph Obermiller , Umesh H. Patel
IPC分类号： A61F2/02
CPC分类号： A61B17/0057 , A61B17/0401 , A61B17/06 , A61B17/06166 , A61B17/3468 , A61B50/30 , A61B2017/00004 , A61B2017/00628 , A61B2017/00641 , A61B2017/00646 , A61B2017/00654 , A61B2017/00659 , A61B2017/00898 , A61B2017/0404 , A61B2017/0464 , A61B2017/0496 , A61B2017/22038 , A61L27/227 , A61L27/24 , A61L27/3616 , A61L27/3629 , A61L27/3633 , A61L27/58 , A61M27/00
摘要： An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and/or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.
摘要翻译：提供了一种植入式移植物，其可以插入瘘道以封闭瘘的主要开口。为了防止移植物的意外移位或将移植物从患者的瘘管挤出，移植物可以设置有从移植物的主体的至少一端侧向延伸的帽，其中帽可以与移植物的主体，可附接到移植物的身体的至少一端，和/或沿着移植物的主体移动。移植物还可以具有从移植物的身体的一端延伸的尾部，以帮助将移植物放置在瘘管道中。移植物可以是由诸如异种移植材料的单一材料制成的整体单元，或者可以包括由相同或不同材料制成的不同部件。还提供了关闭瘘管的方法。

14. 发明授权

US08501217B2 Implantable graft to close a fistula 有权
标题翻译：植入式移植物闭合瘘管
公开(公告)号：US08501217B2
公开(公告)日：2013-08-06
申请号：US13018582
申请日：2011-02-01
申请人： David N. Armstrong , Brain L. Bates , Mark W. Bleyer , F. Joseph Obermiller , Umesh H. Patel
发明人： David N. Armstrong , Brain L. Bates , Mark W. Bleyer , F. Joseph Obermiller , Umesh H. Patel
IPC分类号： A61F2/02
CPC分类号： A61B17/0057 , A61B17/0401 , A61B17/06 , A61B17/06166 , A61B17/3468 , A61B50/30 , A61B2017/00004 , A61B2017/00628 , A61B2017/00641 , A61B2017/00646 , A61B2017/00654 , A61B2017/00659 , A61B2017/00898 , A61B2017/0404 , A61B2017/0464 , A61B2017/0496 , A61B2017/22038 , A61L27/227 , A61L27/24 , A61L27/3616 , A61L27/3629 , A61L27/3633 , A61L27/58 , A61M27/00
摘要： An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and/or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.
摘要翻译：提供了一种植入式移植物，其可以插入瘘道以封闭瘘的主要开口。为了防止移植物的意外移位或将移植物从患者的瘘管挤出，移植物可以设置有从移植物的主体的至少一端侧向延伸的帽，其中帽可以与移植物的主体，可附接到移植物的身体的至少一端，和/或沿着移植物的主体移动。移植物还可以具有从移植物的身体的一端延伸的尾部，以帮助将移植物放置在瘘管道中。移植物可以是由诸如异种移植材料的单一材料制成的整体单元，或者可以包括由相同或不同材料制成的不同部件。还提供了关闭瘘管的方法。

15. 发明授权

US08470356B2 Tissue augmentation devices and methods 有权
标题翻译：组织增强装置和方法
公开(公告)号：US08470356B2
公开(公告)日：2013-06-25
申请号：US12939636
申请日：2010-11-04
申请人： Umesh H. Patel , F. Joseph Obermiller , Bhavin Shah , Chad E. Johnson
发明人： Umesh H. Patel , F. Joseph Obermiller , Bhavin Shah , Chad E. Johnson
IPC分类号： A61M5/158 , C12N5/00 , A61F2/00 , A61M31/00 , A61M5/178 , A61B17/34 , A61B17/04 , A61B17/06 , C12M1/00
CPC分类号： A61F2/0059
摘要： Tissue augmentation devices, as well as methods of manufacturing and using the same, are disclosed. In certain embodiments, a tissue augmentation device comprises an elongate tissue penetrating member and an amount of remodelable material, wherein at least a portion of the elongate member is cannulated, and at least a portion of the amount of material is received within at least a portion of the cannulated portion of the elongate member. The elongate tissue penetrating member may provide at least one deformation that is configured to constrict portions of the amount of remodelable material received within the elongate member. In alternate embodiments, a flexible covering over an implantable biomaterial provides protection and allows an easier delivery of the biomaterial to a tissue tract.
摘要翻译：公开了组织增加装置，以及制造和使用它们的方法。在某些实施例中，组织增强装置包括细长的组织穿透构件和一定量的可重塑材料，其中细长构件的至少一部分被插管，并且至少部分材料量被容纳在至少一部分内的细长构件的插管部分。细长组织穿透构件可以提供至少一个变形，其被构造成收缩在细长构件内容纳的可重塑材料的量的部分。在替代实施例中，可植入生物材料上的柔性覆盖物提供保护并且允许将生物材料更容易地递送到组织道。

16. 发明授权

US07850985B2 Tissue augmentation devices and methods 有权
标题翻译：组织增强装置和方法
公开(公告)号：US07850985B2
公开(公告)日：2010-12-14
申请号：US11481422
申请日：2006-07-05
申请人： Umesh H. Patel , F. Joseph Obermiller , Bhavin Shah , Chad E. Johnson
发明人： Umesh H. Patel , F. Joseph Obermiller , Bhavin Shah , Chad E. Johnson
IPC分类号： A61M5/158 , A61F2/00 , C12N5/00 , A61M5/178 , A61M31/00 , C12M1/00 , A61B17/34 , A61B17/04 , A61B17/06
CPC分类号： A61F2/0059
摘要： Tissue augmentation devices, as well as methods of manufacturing and using the same, are disclosed. In certain embodiments, a tissue augmentation device comprises an elongate tissue penetrating member and an amount of remodelable material, wherein at least a portion of the elongate member is cannulated, and at least a portion of the amount of material is received within at least a portion of the cannulated portion of the elongate member. The elongate tissue penetrating member may provide at least one deformation that is configured to constrict portions of the amount of remodelable material received within the elongate member. In alternate embodiments, a flexible covering over an implantable biomaterial provides protection and allows an easier delivery of the biomaterial to a tissue tract.
摘要翻译：公开了组织增加装置，以及制造和使用它们的方法。在某些实施例中，组织增强装置包括细长的组织穿透构件和一定量的可重塑材料，其中细长构件的至少一部分被插管，并且至少部分材料量被容纳在至少一部分内的细长构件的插管部分。细长组织穿透构件可以提供至少一个变形，其被构造成收缩在细长构件内容纳的可重塑材料的量的部分。在替代实施例中，可植入生物材料上的柔性覆盖物提供保护并且允许将生物材料更容易地递送到组织道。

17. 发明申请

US20080248079A1 TISSUE AUGMENTATION DEVICES AND METHODS 有权
标题翻译：组织补充装置及方法
公开(公告)号：US20080248079A1
公开(公告)日：2008-10-09
申请号：US12114456
申请日：2008-05-02
申请人： Ryan Dempsey , Jeffrey Miller , Steve Chen , Umesh H. Patel , F. Joseph Obermiller , Bhavin Shah , Chad E. Johnson
发明人： Ryan Dempsey , Jeffrey Miller , Steve Chen , Umesh H. Patel , F. Joseph Obermiller , Bhavin Shah , Chad E. Johnson
IPC分类号： A61F2/00 , A61M31/00
CPC分类号： A61F2/0059 , A61B17/06004 , A61B2017/06052 , A61F2/02 , A61L27/24 , A61M5/32 , A61M25/0662 , A61M2025/018 , Y10S623/915
摘要： Tissue augmentation devices, as well as methods of manufacturing and using the same, are disclosed. In certain embodiments, a tissue augmentation device comprises an elongate tissue penetrating member and an amount of remodelable material, wherein at least a portion of the elongate member is cannulated, and at least a portion of the amount of material is received within at least a portion of the cannulated portion of the elongate member. The elongate tissue penetrating member may provide at least one deformation that is configured to constrict portions of the amount of remodelable material received within the elongate member. In alternate embodiments, a flexible covering over an implantable biomaterial provides protection and allows an easier delivery of the biomaterial to a tissue tract.
摘要翻译：公开了组织增加装置，以及制造和使用它们的方法。在某些实施例中，组织增强装置包括细长的组织穿透构件和一定量的可重塑材料，其中细长构件的至少一部分被插管，并且至少部分材料量被容纳在至少一部分内的细长构件的插管部分。细长组织穿透构件可以提供至少一个变形，其被构造成收缩在细长构件内容纳的可重塑材料的量的部分。在替代实施例中，可植入生物材料上的柔性覆盖物提供保护并且允许将生物材料更容易地递送到组织道。

18. 发明授权

US09186140B2 Medical devices and methods useful for applying bolster material 有权
标题翻译：适用于枕垫材料的医疗器械和方法
公开(公告)号：US09186140B2
公开(公告)日：2015-11-17
申请号：US12110006
申请日：2008-04-25
申请人： Michael C. Hiles , Umesh H. Patel , Bhavin Shah , Chad S. McAlexander
发明人： Michael C. Hiles , Umesh H. Patel , Bhavin Shah , Chad S. McAlexander
IPC分类号： A61B17/08 , A61B17/072 , A61B17/00 , A61B19/02 , A61B19/00
CPC分类号： A61B17/07292 , A61B17/00491 , A61B17/0643 , A61B17/0644 , A61B17/072 , A61B17/07207 , A61B50/20 , A61B2017/00884 , A61B2090/037
摘要： Described are medical devices useful for applying a bolster material to a surgical fastening device such as a stapler, and related methods of manufacture and use. The devices include an applicator element for receipt between arms of the stapler, and a bolster material, desirably a remodelable extracellular matrix material, coupled to the applicator element. In certain embodiments, the bolster material is held by the applicator element, for example having at least a portion looped around or received through or over a portion of the applicator element. Also described are unique implantable materials including coatings of dried, reversible adhesive.
摘要翻译：描述了可用于将枕头材料应用于诸如吻合器的外科紧固装置的医疗装置，以及相关的制造和使用方法。这些装置包括用于在吻合器的臂之间接收的施加器元件和耦合到施加器元件的垫片材料，期望地是可重塑的细胞外基质材料。在某些实施例中，枕垫材料被施用器元件保持，例如具有至少部分环绕或接收通过施加器元件的一部分的部分。还描述了独特的可植入材料，包括干燥的可逆粘合剂的涂层。

19. 发明授权

US08920516B2 Graft prosthesis, material and methods 有权
标题翻译：接枝假体，材料和方法
公开(公告)号：US08920516B2
公开(公告)日：2014-12-30
申请号：US12693908
申请日：2010-01-26
申请人： William A. Cook , Michael C. Hiles , Thomas G. Kozma , Umesh H. Patel
发明人： William A. Cook , Michael C. Hiles , Thomas G. Kozma , Umesh H. Patel
IPC分类号： A61F2/02 , A61L27/24 , A61L2/00 , A61L27/36 , A61L27/38 , A61L29/00 , A61L31/00 , A61F2/06 , A61F2/07
CPC分类号： A61L27/24 , A61F2/06 , A61F2/07 , A61L2/0088 , A61L27/3604 , A61L27/3662 , A61L27/3683 , A61L27/3695 , A61L27/3839 , A61L27/3843 , A61L27/386 , A61L29/005 , A61L31/005 , Y10S623/925
摘要： A graft prostheses (11), materials and method for implanting, transplanting, replacing, or repairing a part of a patient. The graft prosthesis includes a purified, collagen-based matrix structure removed from a submucosa tissue source. The submucosa tissue source is purified by disinfection and removal steps to deactivate and remove contaminants, thereby making the purified structure biocompatible and suitable for grafting on and/or in a patient.
摘要翻译：移植假体（11），用于植入，移植，替换或修复患者的一部分的材料和方法。移植假体包括从粘膜下层组织源移除的纯化的基于胶原的基质结构。通过消毒和去除步骤来净化粘膜下组织来源，以去活化和去除污染物，从而使纯化的结构生物相容并适于在患者和/或患者中接枝。

20. 发明授权

US08920443B2 Medical devices and methods useful for applying bolster material 有权
公开(公告)号：US08920443B2
公开(公告)日：2014-12-30
申请号：US11060078
申请日：2005-02-17
申请人： Michael C. Hiles , Umesh H. Patel , Bhavin Shah , Chad S. McAlexander
发明人： Michael C. Hiles , Umesh H. Patel , Bhavin Shah , Chad S. McAlexander
IPC分类号： A61B17/08 , A61B17/072 , A61B17/00 , A61B19/02 , A61B19/00
CPC分类号： A61B17/07292 , A61B17/00491 , A61B17/0643 , A61B17/0644 , A61B17/072 , A61B17/07207 , A61B50/20 , A61B2017/00884 , A61B2090/037
摘要： Described are medical devices useful for applying a bolster material to a surgical fastening device such as a stapler, and related methods of manufacture and use. The devices include an applicator element for receipt between arms of the stapler, and a bolster material, desirably a remodelable extracellular matrix material, coupled to the applicator element. In certain embodiments, the bolster material is held by the applicator element, for example having at least a portion looped around or received through or over a portion of the applicator element. Also described are unique implantable materials including coatings of dried, reversible adhesive.

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