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11. 发明公开

EP2739355A2 DOSE-OPTIMISED PATIENT POSITIONING FOR RADIOTHERAPY 有权转让
标题翻译：剂量，提高了患者定位放射治疗
公开(公告)号：EP2739355A2
公开(公告)日：2014-06-11
申请号：EP11738244.0
申请日：2011-08-02
申请人： Brainlab AG
发明人： GUM, Franz , FROEHLICH, Stephan
IPC分类号： A61N5/10
CPC分类号： A61N5/1039 , A61B6/032 , A61B6/4085 , A61N5/1031 , A61N5/1048 , A61N5/1049 , A61N5/1077 , A61N2005/1061

12. 发明授权

EP3590430B1 RADIATION BEAM POSITIONING 有权
公开(公告)号：EP3590430B1
公开(公告)日：2020-09-09
申请号：EP19190526.4
申请日：2014-07-03
申请人： Brainlab AG
发明人： FROEHLICH, Stephan , BERLINGER, Kajetan , WOHLGEMUTH, Richard
IPC分类号： A61B6/00 , A61N5/10 , A61B90/00 , A61B34/20

13. 发明公开

EP3248652A1 NON-PLANAR TREATMENT BEAM CONTROL 有权
标题翻译：非平面处理梁控制
公开(公告)号：EP3248652A1
公开(公告)日：2017-11-29
申请号：EP17173193.8
申请日：2010-07-23
申请人： Brainlab AG
发明人： BERLINGER, Kajetan , FROEHLICH, Stephan , GUM, Franz
IPC分类号： A61N5/10
CPC分类号： A61N5/1049 , A61N5/10 , A61N5/103 , A61N5/1042 , A61N5/1082
摘要： The present invention relates to a data processing method for determining control data for controlling beam positions which beam positions describe positions which a treatment beam has or would have if emitted by a beam source, the treatment beam being for treating a treatment body part of a patient, said method constituted to be performed by a computer and comprising the steps of:
• providing treatment data which comprise data on a position of the treatment body part;
• providing condition data which describe:
constraints on the beam positions and/or constraints on positional changes of the beam positions, wherein said constraints allow for at least a part of the beam positions to lie not in a common plane;

• providing an arrangement of the beam positions on the basis of the treatment data which arrangement fulfils the condition data;
• determining control data for controlling a change of a relative position of the beam source relative to the treatment body part for changing the beam positions and for controlling an emission of the treatment beam from the beam source, the determined control data being constituted to change the beam positions to follow the provided arrangement of the beam positions and to cause continuous emission of the treatment beam during a continuous change of the beam positions while the beam positions follow at least a part of the arrangement.
摘要翻译：本发明涉及一种用于确定用于控制射束位置的控制数据的数据处理方法，该射束位置描述了治疗射束具有或将由射束源发射的位置，治疗射束用于治疗患者的治疗身体部位所述方法构成为由计算机执行并且包括以下步骤：·提供治疗数据，所述治疗数据包括关于治疗身体部位的位置的数据; ·提供条件数据，其描述：对射束位置的约束和/或对射束位置的位置变化的约束，其中所述约束允许射束位置的至少一部分不在公共平面中; •根据处理数据提供光束位置的布置，该布置满足条件数据; ·确定用于控制束源相对于治疗主体部分的相对位置的改变的控制数据，用于改变束位置并且用于控制来自束源的治疗束的发射，所确定的控制数据被构造成改变光束位置跟随所提供的光束位置的布置并且在光束位置的连续改变期间引起治疗光束的连续发射，而光束位置跟随布置的至少一部分。

14. 发明公开

EP3110331A1 TRACKING SOFT TISSUE IN MEDICAL IMAGES 有权转让
标题翻译： VERFOLGUNG VON WEICHGEWEBE BEI MEDISINISCHEN BILDERN
公开(公告)号：EP3110331A1
公开(公告)日：2017-01-04
申请号：EP14708825.6
申请日：2014-02-26
申请人： Brainlab AG
发明人： BERLINGER, Kajetan , FROEHLICH, Stephan
IPC分类号： A61B6/00 , A61N5/10
CPC分类号： A61N5/1049 , A61B6/022 , A61B6/032 , A61B6/487 , A61B6/5223 , A61B6/5235 , A61B6/5264 , A61B6/5288 , A61B6/541 , A61N5/1067 , A61N5/1068 , A61N5/107 , A61N2005/1061 , G06F19/00 , G06K9/6202 , G06T7/0014 , G06T7/11 , G06T7/248 , G06T7/73 , G06T2207/10021 , G06T2207/10081 , G06T2207/10124 , G06T2207/20104 , G16H50/50
摘要： The present disclosure is directed to a system, method and apparatus for tracking an anatomical body part in a series of x-ray images. The anatomical body part moves due to a vital movement, such as breathing motion of the thorax. The anatomical body part is defined in a CT image acquired beforehand and is associated with a known movement phase during the vital movement. The series of x-ray images of the moving anatomical body part is taken. The movement phase associated with each one of the x-ray images is determined. In one implementation, the system may track the body part movement using external infrared-reflecting markers and a navigation system while taking a series of x-ray images and time-stamping the x-ray images and the positional information for the body part. The time stamps relate each one of the x-ray images with a specific movement phase of the body part. The specific x-ray image being associated with the same movement phase as the CT image is determined and the representation of the anatomical body part defined in the CT image can be determined in the x-ray image by comparing the CT image with the specific x-ray image. The specific x-ray image may be compared to the other x-ray images to find the anatomical body part in those x-ray images and preferably highlight it to be easily recognized by a user.
摘要翻译：本公开涉及用于跟踪一系列X射线图像中的解剖体部分的系统，方法和装置。由于重要的运动，例如胸部呼吸运动，解剖身体部位移动。解剖体部分被定义在事先获得的CT图像中，并且在重要运动期间与已知的运动相关联。拍摄移动解剖体部分的一系列X射线图像。确定与每个X射线图像相关联的移动阶段。在一个实施方案中，系统可以使用外部红外线反射标记和导航系统跟踪身体部位运动，同时采取一系列x射线图像和时间戳X射线图像和身体部位的位置信息。时间戳将身体部位的特定运动相位中的每一个x射线图像相关联。确定与CT图像相同的移动相位的特定X射线图像，并且可以在X射线图像中通过将CT图像与特定x比较来确定在CT图像中定义的解剖体部分的表示 -ray图像。可以将特定的X射线图像与其他x射线图像进行比较以在那些X射线图像中找到解剖体部分，并且优选地突出显示它以便用户容易地识别。

15. 发明公开

EP2900322A1 ISOCENTRIC PATIENT ROTATION FOR DETECTION OF THE POSITION OF A MOVING OBJECT 审中-公开
标题翻译： ISOZENTRISCHE PATITENTENROTATION ZUR DETEKTION DER POSITION EINES BEWEGLICHEN OBJEKTS
公开(公告)号：EP2900322A1
公开(公告)日：2015-08-05
申请号：EP12769390.1
申请日：2012-09-28
申请人： Brainlab AG
发明人： BERLINGER, Kajetan , FROEHLICH, Stephan
IPC分类号： A61N5/10 , G06T7/00 , G06T7/20 , G06T11/00 , A61B6/02 , A61B6/04
CPC分类号： G06T7/0012 , A61B6/025 , A61B6/0492 , A61B6/486 , A61B6/5235 , A61B6/5264 , A61B6/5288 , A61B6/541 , A61N5/1049 , A61N5/1065 , A61N5/1068 , A61N2005/1051 , A61N2005/1059 , G06T7/20 , G06T7/70 , G06T2207/10081 , G06T2207/10112
摘要： The invention relates to a method for determining the position of an object moving within a body, wherein the body is connected to markers, a movement signal is determined based on the measured movement of the markers, images are taken from the object using a camera or detector, wherein the camera or detector is moved with respect to the object, it is determined from which direction or range of angles or segment the most images corresponding to a predefined cycle of the movement signal are taken, and using at least some or all of the images of the segment containing the most images for a specified movement cycle, an image of the object is reconstructed.
摘要翻译：本发明涉及一种用于确定在身体内移动的物体的位置的方法，其中身体连接到标记，基于所测量的标记的移动来确定移动信号，使用照相机从物体拍摄图像，检测器，其中所述照相机或检测器相对于物体移动，确定从哪个方向或角度范围或者划分对应于移动信号的预定周期的大多数图像，并且使用至少部分或全部包含指定运动周期的最多图像的片段的图像，物体的图像被重建。

16. 发明公开

EP3799782A1 HUMAN BODY MEASUREMENT USING THERMOGRAPHIC IMAGES 有权
公开(公告)号：EP3799782A1
公开(公告)日：2021-04-07
申请号：EP20203248.8
申请日：2014-12-02
申请人： Brainlab AG
发明人： FROEHLICH, Stephan , VILSMEIER, Stefan , KAISER, Hagen
IPC分类号： A61B5/01 , G03B35/00 , H04N13/204 , A61N5/10 , A61B5/11 , G01J5/10 , G16H30/40
摘要： A medical data processing method for tracking at least a part of the surface of the body of a patient (P), comprising the steps of:
- measuring, at a first point in time, first locations of a plurality of points on the surface of the body by acquiring at least two two-dimensional image datasets, wherein each two-dimensional image dataset represents a two-dimensional image of at least a part of the surface which comprises the plurality of points, and wherein the two-dimensional images are taken from different and known viewing directions, determining the pixels in the two-dimensional image datasets which show said plurality of points on the surface of the body, and calculating the spatial location of the plurality of points from the locations of the determined pixels in the two-dimensional image datasets and the viewing directions of the two-dimensional images;
- measuring, at a second point in time which is later than the first point in time, second locations of the plurality of points in the same manner as the first locations; and
- calculating a movement of at least the part of the surface of the body from the difference between the first locations and the second locations.

17. 发明公开

EP3590430A1 RADIATION BEAM POSITIONING 有权
公开(公告)号：EP3590430A1
公开(公告)日：2020-01-08
申请号：EP19190526.4
申请日：2014-07-03
申请人： Brainlab AG
发明人： FROEHLICH, Stephan , BERLINGER, Kajetan , WOHLGEMUTH, Richard
IPC分类号： A61B6/00 , A61N5/10 , A61B90/00 , A61B34/20
摘要： The present invention relates to a data processing method for correlating the position of a radiation beam with the position of a target to be irradiated and contained in a structure underlying a repetitive motion comprising a plurality of successive motion cycles, the method comprising the following steps which are constituted to be executed by a computer:
a) acquiring, at a processor of the computer, first external position data, second external position data and third external position data from a tracking system, describing the position of at least one external feature of said structure, for one or more sections of at least one first motion cycle occurring during a first period of time, for one or more sections of at least one second motion cycle occurring during a second period of time, and for one or more sections of at least one third motion cycle occurring during said second period of time, respectively;
b) acquiring, at the processor of the computer, first target position data and second target position data from a first imaging device, describing the position of said target for at least one of said sections of said at least one first motion cycle, and for said sections of said at least one second motion cycle, respectively;
c) determining, by the processor of the computer and based on said first external position data and said first target position data, correlation model data describing a positional correlation of said external position and said target position;
d) determining, by the processor of the computer and based on said correlation model data and said second external position data, second predicted target position data describing a predicted position of said target for one or more sections of said at least one second motion cycle;
e) determining, by the processor of the computer and based on said second target position data and said second predicted target position data, primary verification data describing whether the position of said target for said sections of said at least one second motion cycles is different from said predicted position;
f) acquiring, at the processor of the computer and in case said primary verification data indicates that the position of said target is not different from the predicted position of said target, auxiliary second target position data and auxiliary third target position data from a second imaging device, describing the position of said target for one or more sections of said at least one second motion cycle, and of said at least one third motion cycle, respectively;
g) determining, by the processor of the computer and based on said first and/or said second external position data, said auxiliary second target position data and said third external position data, third predicted target position data describing a predicted position of said target for said sections of said at least one third motion cycle;
h) determining, by the processor of the computer and based on said auxiliary third target position data and said third predicted target position data, secondary verification data describing whether the position of said target for said sections of said at least one third motion cycle is different from said predicted position.

18. 发明公开

EP3226754A1 HUMAN BODY MEASUREMENT USING THERMOGRAPHIC IMAGES 有权
标题翻译：使用热成像图像进行人体测量
公开(公告)号：EP3226754A1
公开(公告)日：2017-10-11
申请号：EP14808585.5
申请日：2014-12-02
申请人： Brainlab AG
发明人： KAISER, Hagen , FROEHLICH, Stephan , VILSMEIER, Stephan
IPC分类号： A61B5/01 , G03B35/00 , H04N13/02
CPC分类号： A61B5/1128 , A61B5/0035 , A61B5/0064 , A61B5/0077 , A61B5/015 , A61B5/055 , A61B5/11 , A61B5/113 , A61B5/7292 , A61B6/032 , A61B6/5247 , A61B2560/0223 , A61B2576/00 , A61B2576/02 , A61N5/1049 , A61N5/1068 , A61N5/1069 , G01J5/00 , G01J5/10 , G01J2005/0077 , G01J2005/0081 , G01R33/4808 , G03B35/02 , G06F19/00 , G06T7/0012 , G06T7/33 , G06T7/70 , G06T2207/10004 , G06T2207/10028 , G06T2207/10048 , G06T2207/10081 , G06T2207/10088 , G06T2207/30196 , H04N13/204 , H04N13/239 , H04N2013/0081
摘要： A medical image processing method performed by a computer, for measuring the spatial location of a point on the surface of a patient's body including: acquiring at least two two-dimensional image datasets, wherein each two-dimensional image dataset represents a two-dimensional image of at least a part of the surface which comprises the point, and wherein the two-dimensional images are taken from different and known viewing directions; determining the pixels in the two-dimensional image datasets which show the point on the surface of the body; and calculating the spatial location of the point from the locations of the determined pixels in the two-dimensional image datasets and the viewing directions of the two-dimensional images; wherein the two-dimensional images are thermographic images.
摘要翻译：一种由计算机执行的用于测量患者身体表面上的点的空间位置的医疗数据处理方法，包括以下步骤： - 获取至少两个二维图像数据集，其中每个二维图像数据集表示构成该点的表面的至少一部分的二维图像，并且其中二维图像取自不同的且已知的观察方向; - 确定在身体表面上显示所述点的二维图像数据集中的像素; 以及 - 根据所述二维图像数据集中的所确定的像素的位置和所述二维图像的观察方向来计算所述点的空间位置; 其中二维图像是热成像图像。

19. 发明公开

EP2595703A1 NON-PLANAR TREATMENT BEAM CONTROL 有权转让
标题翻译： STEUERUNG EINES NICHTPLANAREN BEHANDLUNGSSTRAHLS
公开(公告)号：EP2595703A1
公开(公告)日：2013-05-29
申请号：EP10737038.9
申请日：2010-07-23
申请人： BrainLAB AG
发明人： FROEHLICH, Stephan , GUM, Franz , BERLINGER, Kajetan
IPC分类号： A61N5/10
CPC分类号： A61N5/1049 , A61N5/10 , A61N5/103 , A61N5/1042 , A61N5/1082
摘要： The present invention relates to a data processing method for determining control data for controlling beam positions which beam positions describe positions which a treatment beam has or would have if emitted by a beam source, the treatment beam being for treating a treatment body part of a patient, said method constituted to be performed by a computer and comprising the steps of: • providing treatment data which comprise data on a position of the treatment body part; • providing condition data which describe: constraints on the beam positions and/or constraints on positional changes of the beam positions, wherein said constraints allow for at least a part of the beam positions to lie not in a common plane; • providing an arrangement of the beam positions on the basis of the treatment data which arrangement fulfils the condition data; • determining control data for controlling a change of a relative position of the beam source relative to the treatment body part for changing the beam positions and for controlling an emission of the treatment beam from the beam source, the determined control data being constituted to change the beam positions to follow the provided arrangement of the beam positions and to cause continuous emission of the treatment beam during a continuous change of the beam positions while the beam positions follow at least a part of the arrangement.
摘要翻译：本发明涉及一种用于确定控制数据的数据处理方法，所述控制数据用于控制光束位置，所述光束位置描述了由光束源发射时处理光束具有或将具有的位置，所述处理光束用于治疗患者的治疗主体部分所述方法构成为由计算机执行，并且包括以下步骤：提供治疗数据，其包括关于治疗体部位的位置的数据; 。提供条件数据，其描述：对光束位置的约束和/或对光束位置的位置变化的约束，其中所述约束允许光束位置的至少一部分不在公共平面内; 。基于所述处理数据提供所述光束位置的布置，所述处理数据满足条件数据; 。确定控制数据，用于控制波束源相对于治疗主体部分的相对位置的改变以改变波束位置并且用于控制来自波束源的治疗波束的发射，所确定的控制数据被构造成改变波束遵循所提供的光束位置的布置的位置，并且在光束位置的连续变化期间引起处理光束的连续发射，而光束位置遵循该布置的至少一部分。

20. 发明授权

EP3110331B1 TRACKING SOFT TISSUE IN MEDICAL IMAGES 有权转让
公开(公告)号：EP3110331B1
公开(公告)日：2018-10-10
申请号：EP14708825.6
申请日：2014-02-26
申请人： Brainlab AG
发明人： BERLINGER, Kajetan , FROEHLICH, Stephan
IPC分类号： A61B6/00 , A61N5/10
CPC分类号： A61N5/1049 , A61B6/022 , A61B6/032 , A61B6/487 , A61B6/5223 , A61B6/5235 , A61B6/5264 , A61B6/5288 , A61B6/541 , A61N5/1067 , A61N5/1068 , A61N5/107 , A61N2005/1061 , G06F19/00 , G06K9/6202 , G06T7/0014 , G06T7/11 , G06T7/248 , G06T7/73 , G06T2207/10021 , G06T2207/10081 , G06T2207/10124 , G06T2207/20104 , G16H50/50
摘要： The present disclosure is directed to a system, method and apparatus for tracking an anatomical body part in a series of x-ray images. The anatomical body part moves due to a vital movement, such as breathing motion of the thorax. The anatomical body part is defined in a CT image acquired beforehand and is associated with a known movement phase during the vital movement. The series of x-ray images of the moving anatomical body part is taken. The movement phase associated with each one of the x-ray images is determined. In one implementation, the system may track the body part movement using external infrared-reflecting markers and a navigation system while taking a series of x-ray images and time-stamping the x-ray images and the positional information for the body part. The time stamps relate each one of the x-ray images with a specific movement phase of the body part. The specific x-ray image being associated with the same movement phase as the CT image is determined and the representation of the anatomical body part defined in the CT image can be determined in the x-ray image by comparing the CT image with the specific x-ray image. The specific x-ray image may be compared to the other x-ray images to find the anatomical body part in those x-ray images and preferably highlight it to be easily recognized by a user.

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