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    • 11. 发明专利
    • DERIVADOS INSECTICIDAS DE BENCILAMINAS SUSTITUIDAS
    • CO6210741A2
    • 2010-10-20
    • CO09094512
    • 2009-09-04
    • BAYER CROPSCIENCE AG
    • ARNOLD CHRISTIANGORGENS ULRICHSCHWARZ HANS-GEORGHOLMWOOD GRAHAMANDREE ROLANDMALSAM OLGASCHALLNER OTTOFRANKEN EVA-MARIAANTONICEK HORST-PETERWERNER STEFAN
    • A01N43/76A01P7/00A01P9/00C07D263/28
    • 1.- Compuestos de fórmula (I)en la que R1, R2, R3, R4 y R5 independientemente entre sí representan hidrógeno, halógeno, hidroxi, alquilo, alcoxi, haloalquilo, alcoxialquilo, cicloalquilo, cianoalquilo, haloalcoxi, alquiltio, haloalquiltio, alquilsulfonilo, alquilsulfoniloxi, halogenoalquilsulfonilo, halogenoalquilsulfoniloxi, alcoxicarbonilo, acetilo, alquilcarbonilo, alquenilcarbonilo, pentafluorosulfanilo, amino, mono y dialquilamino, cicloalquilamino, alquenilo, haloalquenilo, alquinilo, haloalquinilo, ciano o nitro, o representan independientemente entre sí arilo, ariloxi o heteroarilo que están opcionalmente sustituidos con uno o más sustituyentes seleccionados de halógeno, alquilo, haloalquilo, alcoxi, haloalcoxi, alcoxicarbonilo, nitro y ciano;R6 y R7 independientemente entre sí representan hidrógeno, alquilo, haloalquilo, cicloalquilo, alcoxialquilo, alquilmercaptoalquilo, alquenilo o alquinilo, o representan independientemente entre sí arilo, heteroarilo o heterociclilo, opcionalmente sustituidos con uno o más sustituyentes seleccionados de halógeno, alquilo, alcoxi, nitro y ciano; R8 representa -C(Z)R10, -C(Z)OR10 o -C(Z)NR11R12; Z representa O o S; R9 representa hidrógeno, alquilo o haloalquilo; R10 representa alquilo C1-C2, sustituido con uno o más sustituyentes seleccionados de halógeno, alcoxi, alquilmercapto y ciano, o representa alquilo C3-C6, cicloalquilo o bencilo, opcionalmente sustituidos con uno o más sustituyentes seleccionados de halógeno y alcoxi; R11 representa alquilo C1-C2, sustituido con uno o más sustituyentes seleccionados de halógeno, alcoxi, alquilmercapto, alcoxicarbonilo, alquilsulfinilo, alquilsulfonilo y ciano, o representa alquilo C3-C8, cicloalquilo, cicloalquilalquilo, alquenilo o alquinilo, opcionalmente sustituidos con uno o más sustituyentes seleccionados de halógeno, haloalquilo, alcoxi, alquilmercapto, alquilsulfinilo, alquilsulfonilo, dialquilamino, alcoxicarbonilo y dialquilaminocarbonilo, o representa arilalquilo, heterociclilo, heterociclilalquilo, arilo, heteroarilo o heteroarilalquilo, ...
    • 18. 发明专利
    • Use of 7A-substituted hexahydro-1H-pyrrolizine compound e.g. to combat animal parasite, to produce plant protecting agent, to treat seeds, and to stimulate transgenic seeds
    • DE102006050794A1
    • 2008-04-30
    • DE102006050794
    • 2006-10-27
    • BAYER CROPSCIENCE AG
    • HEIL MARKUSDREWES MARK WILHELMFRANKEN EVA-MARIAMALSAM OLGAARNOLD CHRISTIANEBBINGHAUS-KINTSCHER ULRICHANTONICEK HORST-PETERFUESLEIN MARTIN
    • A01N43/90A01P5/00A01P7/02A01P7/04
    • Use of 7A-substituted hexahydro-1H-pyrrolizine compound (I) to combat animal parasite, is claimed. Use of 7A-substituted hexahydro-1H-pyrrolizine compound of formula (I) to combat animal parasite, is claimed. A : an isoxazole unit of formula (a), 1H-pyrazole unit of formula (b), pyridine unit of formula (c), pyrimidine unit of formula (d), pyrazine unit of formula (e), pyridazine unit of formula (f) or quinoline unit of formula (g); R1>1-3C alkyl, -CH2-aryl, -CH2-substituted aryl or -CH2-CH2-substituted aryl, where aryl is phenyl, 1- or 2-naphthyl or biphenyl, and substituted aryl is phenyl, 1-or 2-naphthyl or biphenyl substituted with one or two substituents of alkyl with up to 6C atoms, haloalkyl up to 6C atoms, alkoxy with up to 6C atoms, alkoxyalkyl, in which the alkoxy- and alkyl part contain up to 6C atom, alkoxyalkoxyl, in which the alkoxy part contain up to 6C atom, halo, cyano, OH, amino, alkylamino with up to 6C atom, carboxyl or alkoxycarbonyl with 2-6C; R2>H or 1-3C alkyl; R3>H, 1-3C alkyl, Br, Cl or F (which are substituted at 2-, 4- or 6-position); R4>H, 1-3C alkyl, Br, Cl, F or 1-3C alkyl-O- (where R4> is substituted at one of the remaining positions that are not occupied by R3>), if R4> is substituted at 5-position then R4> is O-R6>, S-R6>, -N(R6>)(R7>) or LR8>; R6>alkylamino with up to 6C atom, dialkylamino, in which the two alkyl group contain 1-6C atom, phenyl, naphthyl, biphenyl, furyl, thienyl, pyridinyl, pyrazinyl, pyridazinyl, pyrimidinyl, pyrrolyl, pyrazolyl, imidazolyl, indolyl, thiazolyl, oxazolyl, isoxazolyl, thiadiazolyl, oxadiazolyl, quinolinyl, isoquinolinyl, aryl-1-6C alkyl, heteroaryl-1-6C alkyl (all substituted with 1-6C alkyl, haloalkyl with up to 6C atom, alkoxy with up to 6C atom, alkoxyalkyl, in which the alkoxy- and alkyl part contain up to 6C atoms, halo, cyano, OH, amino, alkylamino with up to 6C atoms, carboxyl or 2-6C alkoxycarbonyl), H, alkyl with up to 6C atom, alkenyl with up to 6C atom, alkynyl with up to 6C atom, haloalkyl with up to 6C atom, hydroxyalkyl with 2-6C atom or amino; L : -(CH2)p-, -(CH=CH)q-, -C(O)-, -OC(O)-, -N(R7>)-C(O)-, -CH2-CH2-C(O)-, -CH2-O-C(O)-, -CH2-NH-C(O)- or -C?=C-; R7>H or 1-6C alkyl; R8>alkylamino with up to 6C atoms, dialkylamino, in which the two alkyl group contain 1-6C atom, phenyl, naphthyl, biphenyl, furyl, thienyl, pyridinyl, pyrazinyl, pyridazinyl, pyrimidinyl, pyrrolyl, pyrazolyl, imidazolyl, indolyl, thiazolyl, oxazolyl, isoxazolyl, thiadiazolyl, oxadiazolyl, quinolinyl, isoquinolinyl (all substituted with 1-6C alkyl, haloalkyl with up to 6C atom, alkoxy with up to 6C atom, alkoxyalkyl, in which the alkoxy- and alkyl part contain up to 6C atoms, halo, cyano, OH, amino, alkylamino with up to 6C atoms, carboxyl or 2-6C alkoxycarbonyl), H, alkyl with up to 6C atoms, alkenyl with up to 6C atom, alkynyl with up to 6C atom, haloalkyl with up to 6C atom, hydroxyalkyl with up to 6C atom or amino, where -O-R6>, -S-R6>, -N(R6>)(R7>) and LR8>, which are in conjugation with a double bond or triple bond does not contain a nitrogen atom; R5>H, 1-3C alkyl, Cl or F; p : 1-6; and q : up to 2. [Image] [Image] ACTIVITY : Antiparasitic; Insecticide; Arachnicide; Nematocide; Plant Protectant. MECHANISM OF ACTION : None given.