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11. 发明申请

WO2010091963A2 STABILIZATION OF COSMETIC COMPOSITIONS 审中-公开
标题翻译：化妆品组合物的稳定性
公开(公告)号：WO2010091963A2
公开(公告)日：2010-08-19
申请号：PCT/EP2010/051011
申请日：2010-01-28
申请人： BASF SE , HERZOG, Bernd , GRUMELARD, Julie
发明人： HERZOG, Bernd , GRUMELARD, Julie
IPC分类号： A61K8/35 , A61K8/37 , A61K8/40 , A61K8/41 , A61K8/49 , A61Q17/04
CPC分类号： A61K8/494 , A61K8/36 , A61K8/37 , A61K8/40 , A61K8/41 , A61K8/411 , A61K8/496 , A61K8/4966 , A61K2800/52 , A61K2800/592 , A61Q17/04
摘要： Disclosed is the Use of UV absorbers selected from (a 1 ) diphenylacrylates; and (a 2 ) specific hydroxyphenyl triazines for stabilizing cosmetic compositions comprising an organic UV absorber selected from (b 1 ) a specific benzophenone derivative, (b 2 ) a specific benzotriazole derivative and (b 3 ) a specific triazine derivative and UV filters selected from (c 1 ) cinnamic acid derivatives; and (c 2 ) dibenzoylmethane derivatives.
摘要翻译：公开了使用选自（a1）二苯基丙烯酸酯的UV吸收剂; 和（a2）用于稳定化妆品组合物的特定羟基苯基三嗪，其包含选自（b1）特定二苯甲酮衍生物，（b2）特定苯并三唑衍生物和（b3）特定三嗪衍生物的有机UV吸收剂和选自（c1）肉桂酸酸衍生物; 和（c2）二苯甲酰甲烷衍生物。

12. 发明申请

WO2013076075A2 USE OF OLEOGELS IN UV ABSORBER COMPOSITIONS 审中-公开
标题翻译：紫外线吸收剂组合物中OLEOGELS的使用
公开(公告)号：WO2013076075A2
公开(公告)日：2013-05-30
申请号：PCT/EP2012/073095
申请日：2012-11-20
申请人： BASF SE , HERZOG, Bernd , DESHAYES, Cyrille
发明人： HERZOG, Bernd , DESHAYES, Cyrille
IPC分类号： A61K8/26 , A61K8/37 , A61Q17/04 , A61K8/04
CPC分类号： A61K8/042 , A61K8/26 , A61K8/31 , A61K8/34 , A61K8/342 , A61K8/37 , A61K8/375 , A61K8/4966 , A61K8/891 , A61K8/922 , A61Q17/04
摘要： Disclosed is the use of oleogels (a) for increasing the sun protection factor of sunscreens comprising at least one organic or inorganic UV filter (b).
摘要翻译：公开了使用油凝胶（a）来增加包含至少一种有机或无机紫外线过滤器（b）的防晒剂的防晒系数。

13. 发明申请

WO2009027390A3 STABILIZATION OF COSMETIC COMPOSITIONS 审中-公开
公开(公告)号：WO2009027390A3
公开(公告)日：2009-03-05
申请号：PCT/EP2008/061132
申请日：2008-08-26
申请人： BASF SE , HERZOG, Bernd , QUASS, Katja , ACKER, Stephanie
发明人： HERZOG, Bernd , QUASS, Katja , ACKER, Stephanie
IPC分类号： A61K8/37 , A61K8/49 , A61Q17/04
摘要： Disclosed is the use of UV absorbers selected from (a 1 ) diphenylacrylates; (a 2 ) hydroxyphenyl triazines of formula (1), in which R 1 , R 2 and R 3 independently of one another, are C 1 -C 18 alkyl; (a 3 ) benzotriazole derivatives of formula (2), wherein R 4 is a random statistical mixture of at least three isomeric branched secondary alkyl groups each having 8 to 30 carbon atoms and having the formula (2a); E 1 is a straight-chain C 1 -C 14 alkyl; E 2 is a straight-chain C 4 -C 15 alkyl; wherein the total number of carbon atoms in E 1 plus E 2 is from 7 to 29; and R 5 is C 1 -C 5 alkyl; and (a 4 ) dialkyl naphthalate; for stabilizing cosmetic compositions comprising (b) symmetrical triazine derivatives of formula (3), wherein A is a radical of formula (3a); or (3b) R 6 and R 10 independently from each other are hydrogen; C 1 -C 18 alkyl; or C 6 -C 12 aryl; R 7 , R 8 and R 9 independently from each other are hydrogen; or a radical of formula (3c), wherein, in formula (3a), at least one of the radicals R 7 , R 8 and R 9 are a radical of formula (3c); R 11 , R 12 , R 13 and R 14 independently from each other are hydrogen; hydroxy; halogen; C 1 -C 18 alkyl; C 1 -C 18 alkoxy; C 6 -C 12 aryl; biphenylyl; C 6 -C 12 aryloxy; C 1 -C 18 alkylthio; carboxy; -COOM; C 1 -C 18 -alkylcarboxyl; aminocarbonyl; mono- or di-C 1 -C 18 alkylamino; C 1 -C 10 acylamino; or -COOH; M is an alkali metal ion; x is 1 or 2; and y is a number from 2 to 10; and a UV-absorber selected from (c 1 ) cinnamic acid derivatives; and (C 2 ) dibenzoylmethane derivatives.

14. 发明申请

WO2009007264A2 WATER BASED CONCENTRATED PRODUCT FORMS OF OIL-SOLUBLE ORGANIC UV ABSORBERS 审中-公开
标题翻译：水溶性有机紫外线吸收剂的浓缩产品形式
公开(公告)号：WO2009007264A2
公开(公告)日：2009-01-15
申请号：PCT/EP2008/058356
申请日：2008-06-30
申请人： CIBA HOLDING INC. , MÜLLER, Stefan , LINDEMANN, Brigitte , HERZOG, Bernd
发明人： MÜLLER, Stefan , LINDEMANN, Brigitte , HERZOG, Bernd
IPC分类号： A61K8/11 , A61K8/35 , A61K8/37 , A61K8/44 , A61K8/49 , A61K8/81 , A61Q17/04
CPC分类号： A61Q17/04 , A61K8/11 , A61K8/35 , A61K8/37 , A61K8/44 , A61K8/445 , A61K8/496 , A61K8/4966 , A61K8/585 , A61K8/8152 , A61K8/893 , A61K2800/413
摘要： The instant invention refers to the use of a concentrated aqueous polymer dispersion with an average particle size of less than 1000 nm comprising (a) a polymer carrier prepared by heterophase radical polymerization of at least one ethylenically unsaturated monomer in the presence of (b) an oil-soluble organic UV absorber selected from the class of p-aminobenzoic acid derivatives; salicylic acid derivatives; benzophenone derivatives; diphenyl acrylate derivatives; benzofuran derivatives; polymeric UV absorbers, comprising one or more organosilicon radicals; cinnamic acid derivatives; camphor derivatives; s-triazine derivatives; trianilino-s-triazine derivatives; menthyl anthranilates; and benzotriazole derivatives; wherein the weight ratio of the oil-soluble organic UV absorber (b) to polymer carrier (a) is greater than 50 parts UV absorber per 100 parts of carrier; for the protection of human and animal hair and skin against the damaging effect of UV radiation. The concentrated aqueous polymer dispersions show unexpectedly high sunscreen effects and a positive skin feeling.
摘要翻译：本发明涉及使用平均粒度小于1000nm的浓聚合物水分散体分散体，其包含（a）通过至少一种烯键式不饱和单体的异相自由基聚合制备的聚合物载体在（b）选自对氨基苯甲酸衍生物类的油溶性有机UV吸收剂存在下; 水杨酸衍生物; 二苯甲酮衍生物; 丙烯酸二苯酯衍生物; 苯并呋喃衍生物; 包含一个或多个有机硅基团的聚合物UV吸收剂; 肉桂酸衍生物; 樟脑衍生物; 均三嗪衍生物; 三苯胺基-s-三嗪衍生物; 邻氨基苯甲酸薄荷酯; 和苯并三唑衍生物; 其中油溶性有机紫外线吸收剂（b）与聚合物载体（a）的重量比大于50份UV吸收剂/ 100份载体; 用于保护人类和动物毛发和皮肤免受紫外线辐射的破坏性影响。浓缩的聚合物水分散体表现出意想不到的高防晒效果和正面的皮肤感觉。

15. 发明申请

WO2009003934A1 PREPARATION OF NANOSCALAR UV ABSORBERS 审中-公开
标题翻译：纳米紫外线吸收剂的制备
公开(公告)号：WO2009003934A1
公开(公告)日：2009-01-08
申请号：PCT/EP2008/058250
申请日：2008-06-27
申请人： CIBA HOLDING INC. , MÜLLER, Stefan , HERZOG, Bernd
发明人： MÜLLER, Stefan , HERZOG, Bernd
IPC分类号： C07D251/24 , A61K8/49
CPC分类号： C07D251/24 , A61K8/4966 , A61K2800/412 , A61K2800/413 , A61Q17/04 , B82Y5/00
摘要： Disclosed is a method of preparing a composition, comprising a micronised insoluble organicUV absorber, which method comprises grinding the insoluble organic UV absorber, in coarse particle form, in a grinding apparatus comprising yttrium-stabilized zirconium oxide grinding beads, in the presence of alkyl polyglucoside having the formula C n H 2n +1 O(C 6 H 10 O 5 ) x H, in which n is an integer ranging from 8 to 16 and x is the mean polymerisation level of the glucoside moiety (C 6 H 10 O 5 ) and ranges from 1.4 to 1.6, or an ester thereof and in the presence of an antifoam agent as dispersingagent auxiliary.
摘要翻译：公开了一种制备组合物的方法，该组合物包含微粉化的不溶性有机紫外线吸收剂，该方法包括在包含钇稳定的氧化锆研磨珠的研磨装置中，在烷基聚葡糖苷存在下研磨粗颗粒形式的不溶性有机UV吸收剂具有式C n H 2n + 10（C 6 H 10 O 5）x H，其中n是8至16的整数，x是葡萄糖苷部分（C 6 H 10 O 5）的平均聚合水平，范围为1.4至1.6，或其酯消泡剂作为分散助剂的存在。

16. 发明申请

WO2007048645A2 PROTECTION OF OXIDIZABLE AGENTS 审中-公开
标题翻译：氧化剂的保护
公开(公告)号：WO2007048645A2
公开(公告)日：2007-05-03
申请号：PCT/EP2006/063421
申请日：2006-06-21
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , MONGIAT, Sébastien , BASCHONG, Werner , HERZOG, Bernd
发明人： MONGIAT, Sébastien , BASCHONG, Werner , HERZOG, Bernd
CPC分类号： A61K31/05 , A61K8/11 , A61K8/14 , A61K8/347 , A61K8/37 , A61K8/375 , A61K8/42 , A61K8/46 , A61K8/466 , A61K8/4926 , A61K8/4966 , A61K8/4973 , A61K8/553 , A61K8/671 , A61K8/676 , A61K31/222 , A61K31/255 , A61K31/34 , A61K31/445 , A61K2800/412 , A61K2800/413 , A61K2800/522 , A61Q1/02 , A61Q5/02 , A61Q11/00 , A61Q17/04 , A61Q19/00 , A61Q19/10
摘要： Formulations for cosmetical or pharmaceutical use contain an antioxidant in encapsulated form and a cosmetically or pharmaceutically acceptable carrier. The antioxidant is selected from carbon bridged hindered phenoles, ester bridged hindered phenoles, amide bridged hindered phenoles, lactones of hindered phenoles, sterically hindered oxylamines and sterically hindered hydroxylamines. The encapsulated antioxidant is of high activity and suitable to protect a further active ingredient, e.g. oxidizable natural substances, vitamins, fragrances, and extracts from plants fungi, algae or animals, from premature degradation, especially when coencapsulated together with the ingredient. The formulations are useful inter alia for the preparation of a cosmetical or pharmaceutical skin care or skin delivery formulation, injectable solution, infusion solution, eye drop, drinking solution, a dietary or enriched food, an oral care formulation, drinking gargles, in-halants, or as a food additive.
摘要翻译：用于化妆品或药物用途的制剂含有包封形式的抗氧化剂和美容或药学上可接受的载体。抗氧化剂选自碳桥接的受阻酚，酯桥接的受阻酚，酰胺桥接的受阻酚，受阻酚的内酯，空间位阻的羟胺和空间位阻羟胺。包封的抗氧化剂具有高活性并且适合于保护另外的活性成分，例如，可以从植物真菌，藻类或动物中提取的可氧化的天然物质，维生素，香料，过早降解，特别是当与成分一起胶囊时。该制剂尤其用于制备美容或药物皮肤护理或皮肤递送制剂，可注射溶液，输注溶液，滴眼剂，饮用溶液，饮食或富含食物，口腔护理制剂，饮用漱口剂，漱口剂，或作为食品添加剂。

17. 发明申请

WO2009016064A1 USE OF NANODISPERSIONS TO PROTECT WATER-SOLUBLE INGREDIENTS IN COSMETIC END FORMULATIONS 审中-公开
标题翻译：使用纳米尺寸来保护化妆品配方中的水溶性成分
公开(公告)号：WO2009016064A1
公开(公告)日：2009-02-05
申请号：PCT/EP2008/059568
申请日：2008-07-22
申请人： CIBA HOLDING INC. , MONGIAT, Sébastien , GRUMELARD, Julie , BASCHONG, Werner , HERZOG, Bernd
发明人： MONGIAT, Sébastien , GRUMELARD, Julie , BASCHONG, Werner , HERZOG, Bernd
IPC分类号： A61K8/04 , A61K8/55 , A61K8/60 , A61K8/891 , A61Q5/00 , A61Q19/00
CPC分类号： A61K8/676 , A61K8/04 , A61K8/345 , A61K8/375 , A61K8/4993 , A61K8/553 , A61K8/68 , A61K8/86 , A61K8/894 , A61K8/898 , A61K8/90 , A61K2800/413 , A61K2800/52 , A61K2800/522 , A61Q19/00 , B82Y5/00
摘要： The invention describes the use of a nanodispersion, which comprises: a) a membrane-forming molecule, b) a coemulsifier, c) a lipophilic component, and d) a water-soluble ingredient sensitive to oxidation in cosmetic end formulations, the nanodispersion being obtainable by (α) mixing the components (a), (b) and (c) until a homogeneous liquid is obtained (so-called nanodispersion pre-phase), and (β) adding the water or aqueous phase (discontinuous phase) which contains the water-soluble ingredient and optionally the non-aqueous polar organic solvent to the liquid obtained in step (α). Component (d) is preferably ascorbic acid or vitamin C.
摘要翻译：本发明描述了纳米分散体的使用，其包括：a）成膜分子，b）共乳化剂，c）亲脂性组分，和d）在化妆品末端制剂中对氧化敏感的水溶性成分，纳米分散体可通过（a）将组分（a），（b）和（c）混合直到获得均匀的液体（所谓的纳米分散前相）和（ß）加入水或水相（不连续相）在步骤（a）中得到的液体含有水溶性成分和任选的非水极性有机溶剂。组分（d）优选为抗坏血酸或维生素C.

18. 发明申请

WO2006034968A1 PHOTO-STABLE COSMETIC OR DERMATOLOGICAL COMPOSITIONS 审中-公开
标题翻译：光稳定的化妆品或皮肤组合物
公开(公告)号：WO2006034968A1
公开(公告)日：2006-04-06
申请号：PCT/EP2005/054641
申请日：2005-09-19
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , MÜLLER, Stefan , HERZOG, Bernd , QUASS, Katja
发明人： MÜLLER, Stefan , HERZOG, Bernd , QUASS, Katja
IPC分类号： A61K8/40 , A61K8/41 , A61K8/35 , A61Q17/04 , A61Q5/02 , A61Q5/12 , A61K8/897 , A61K8/37 , A61K8/97 , A61P17/16
CPC分类号： A61K8/066 , A61K8/35 , A61K8/37 , A61K8/40 , A61K8/415 , A61K8/893 , A61K8/97 , A61K2800/52 , A61K2800/57 , A61Q5/02 , A61Q5/12 , A61Q17/04 , A61Q19/00
摘要： Diclosed is the use of an effective photo-stabilizing amount of stabilizing agent (a) selected from a diphenylacrylate UV filter (a1), a benzylidene amphor derivative (a2), an organosiloxane comrising benzalemalonate groups (a3), a fluoren derivative (a4), and a naphthalene dicarboxylic acid derivative (a5) for improving the stability with respect to UV radiation of a cosmetic or dermatological composition comprising a UV filter combination of at least one dibenzoylmethane derivative (b) and of at least one specific amino-substituted 2-hydroxybenzophenone derivative (c).
摘要翻译：封闭的是使用有效的光稳定剂量的选自二苯基丙烯酸酯紫外线过滤器（a1），亚苄基双酚衍生物（a2），含有亚苄基丙二酸酯基团（a3）的有机硅氧烷，芴衍生物（a4）和用于提高化妆品或皮肤病学组合物的UV辐射稳定性的萘二羧酸衍生物（a5），其包含至少一种二苯甲酰甲烷衍生物（b）和至少一种特定氨基取代的2- 羟基二苯甲酮衍生物（c）。

19. 发明申请

WO2022157011A1 A METHOD AND A SYSTEM FOR UV PROTECTION PREDICTION OF A SUNSCREEN PRODUCT 审中-公开
公开(公告)号：WO2022157011A1
公开(公告)日：2022-07-28
申请号：PCT/EP2022/050120
申请日：2022-01-05
申请人： BASF SE , THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE , CAMBRIDGE CENTRE FOR ADVANCED RESEARCH AND EDUCATION IN SINGAPORE LTD. , LEE, Dong Ryeol
发明人： XIA, Jun Tao , SOHN, Myriam , HERZOG, Bernd , CAO, Liwei , LAPKIN, Alexei
IPC分类号： G16C20/30 , G16C20/70
摘要： The present invention relates to a method and a system for UV protection prediction of a sunscreen product, comprising a) selecting the features of the sunscreen product, wherein the features include a viscosity, a high polarity emollient, a medium polarity emollient, a low polarity emollient, a UVA filter, a UVB filter, a ratio of UVB filter vs UVA filter, a ratio of UV filter in oil phase vs UV filter in water phase, and a ratio of absorbing type UV filter vs scattering/reflecting type UV filter; c) inputting the features into a predictive model, which is built and fitted by using one or more machine learning techniques; and d) calculating the UV protection prediction value of the sunscreen product by the predictive model of step c).

20. 发明申请

WO2020182936A1 SUNSCREEN COMPOSITIONS CONTAINING POROUS METAL OXIDE SPHERES 审中-公开
公开(公告)号：WO2020182936A1
公开(公告)日：2020-09-17
申请号：PCT/EP2020/056628
申请日：2020-03-12
申请人： BASF SE
发明人： HERZOG, Bernd , LINDEMANN, Brigitte , CREMER, Christian , DARJI, Rupa
IPC分类号： A61K8/02 , A61K8/25 , A61K8/27 , A61K8/29 , A61K8/37 , A61K8/41 , A61K8/46 , A61K8/49 , A61Q17/04
摘要： The present invention relates to a method for increasing sun protection factor (SPF) of a sunscreen composition, use of porous metal oxide spheres (e.g., microspheres) for increasing SPF of a sunscreen composition and preparation of sunscreen compositions comprising the porous spheres.

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