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11. 发明申请

US20130190377A1 Novel Lactams 有权
标题翻译：小说里加斯
公开(公告)号：US20130190377A1
公开(公告)日：2013-07-25
申请号：US12087862
申请日：2007-01-24
申请人： Naresh Kumar , George Iskander
发明人： Naresh Kumar , George Iskander
IPC分类号： C07D207/38 , C08F26/06 , A01N43/36 , C07D207/273 , C07D207/27
CPC分类号： C07D207/44 , A01N43/36 , C07D207/27 , C07D207/273 , C07D207/36 , C07D207/38 , C08F26/06 , A01N25/10
摘要： The present invention relates to novel lactams of formulae (I) and (II). The present invention further relates to the use of these compounds in the treatment of microbial infections and microbial contamination of surfaces, particularly infections and surface contaminations characterised by biofilm formation. Further provided are compounds of formula (I) and (II) substituted with acrylate or methacrylate groups and their attachment to surfaces or polymers to inhibit microbial contamination.
摘要翻译：本发明涉及式（I）和（II）的新型内酰胺。本发明还涉及这些化合物在治疗表面的微生物感染和微生物污染的用途，特别是以生物膜形成为特征的感染和表面污染物。还提供了用丙烯酸酯或甲基丙烯酸酯基团取代的式（I）和（II）化合物及其与表面或聚合物的连接以抑制微生物污染。

12. 发明申请

US20110283003A1 SYSTEM AND METHOD FOR BILLING SYSTEM INTERFACE FAILOVER RESOLUTION 有权
标题翻译：用于计费系统界面故障分解的系统和方法
公开(公告)号：US20110283003A1
公开(公告)日：2011-11-17
申请号：US13189524
申请日：2011-07-24
申请人： Naresh Kumar , Robert Perry
发明人： Naresh Kumar , Robert Perry
IPC分类号： G06F15/16
CPC分类号： H04L12/14 , G06F11/2033 , G06F11/2038 , G06F11/2041 , H04L12/1403 , H04L69/40 , H04M15/70 , H04M15/74 , H04M2215/70 , H04M2215/709
摘要： A determination is made whether a first application server of a group of N application servers, N being at least two, is a coordinator of the group. Responsive to determining that the first application server is the coordinator of the group, a connection to a billing system is established, via a terminal server, by the first application server. A determination is made whether a second application server of the group of N application servers is the coordinator of the group. Responsive to determining that the second application server is not the coordinator of the group, a periodic check is made whether the second application server of the group of N application servers is the coordinator of the group. The second application server may later be determined to be the coordinator of the group, when the first server experiences difficulty. Once it is determined that the second application server now is the coordinator of the group, a connection is established to the billing system, via the terminal server, by the second application server.
摘要翻译：确定一组N个应用服务器的第一应用服务器是否为该组的协调器，N至少为两个。响应于确定第一应用服务器是该组的协调器，通过终端服务器由第一应用服务器建立与计费系统的连接。确定N个应用服务器组的第二应用服务器是否是该组的协调器。响应于确定第二应用服务器不是组的协调器，定期检查N个应用服务器组中的第二应用服务器是否是该组的协调器。当第一服务器遇到困难时，可以将第二应用服务器确定为该组的协调器。一旦确定第二应用服务器现在是组的协调器，则通过第二应用服务器经由终端服务器向计费系统建立连接。

13. 发明授权

US07945960B2 Dynamic conditional security policy extensions 有权
标题翻译：动态条件安全策略扩展
公开(公告)号：US07945960B2
公开(公告)日：2011-05-17
申请号：US11296086
申请日：2005-12-06
申请人： Raymond K. Ng , Ganesh Kirti , Thomas Keefe , Naresh Kumar
发明人： Raymond K. Ng , Ganesh Kirti , Thomas Keefe , Naresh Kumar
IPC分类号： H04L9/32
CPC分类号： H04L63/08
摘要： Systems, methods, and machine-readable media are disclosed for providing conditional grants of permission in an externally configured security policy. In one embodiment, a method is provided which comprises reading a condition clause from a grant statement defined in the security policy. The grant statement can cause the granting of permission for a user to access a requested resource. One or more constraints on the grant statement can be determined based on the condition clause. Permission can be granted to access the requested resource based on the one or more constraints.
摘要翻译：公开了用于在外部配置的安全策略中提供有限许可的系统，方法和机器可读介质。在一个实施例中，提供了一种方法，其包括从安全策略中定义的授权语句读取条件子句。授权语句可能导致授予用户访问所请求资源的权限。授权语句的一个或多个约束可以基于条件子句来确定。可以授予权限以基于一个或多个约束来访问所请求的资源。

14. 发明授权

US07700644B2 Isoflavonoid dimers 失效
标题翻译：异黄酮二聚体
公开(公告)号：US07700644B2
公开(公告)日：2010-04-20
申请号：US11909538
申请日：2006-03-24
申请人： Andrew Heaton , Naresh Kumar
发明人： Andrew Heaton , Naresh Kumar
IPC分类号： A61K31/352 , C07D493/04
CPC分类号： C07D493/04
摘要： Novel compounds based on phenyl-substituted naphtho[1,2-g]chrysene compounds (A) are described. The compounds are obtainable by dimerisation of 3-phenylchroman (isoflavonoid) ring systems (B). Methods of synthesis of the novel dimeric compounds, compositions containing same and use of the dimers as therapeutic agents are also described.
摘要翻译：描述了基于苯基取代萘并[1,2-g]化合物（A）的新型化合物。该化合物可通过3-苯基苯并二氢吡喃（异黄酮）环体系（B）的二聚得到。还描述了新型二聚化合物的合成方法，含有它们的组合物和二聚体作为治疗剂的用途。

15. 发明申请

US20090048461A1 Regulators of Bacterial Signalling Pathways 审中-公开
标题翻译：细菌信号通路调节剂
公开(公告)号：US20090048461A1
公开(公告)日：2009-02-19
申请号：US11571033
申请日：2005-06-21
申请人： Naresh Kumar
发明人： Naresh Kumar
IPC分类号： C07C69/66 , C07C45/65
CPC分类号： C11D3/48 , A01N31/02 , A01N35/02 , A61K8/35 , A61Q5/02 , A61Q19/10 , C07C45/676 , C07C49/227 , C07C49/235 , C11D3/24
摘要： The present invention provides a method for the preparation of compounds of formula (II). The invention also provides novel compounds of formula (II) and their use in medical, scientific and/or biological applications.
摘要翻译：本发明提供了制备式（II）化合物的方法。本发明还提供新的式（II）化合物及其在医学，科学和/或生物应用中的用途。

16. 发明授权

US07488494B2 Compositions and therapeutic methods involving isoflavones and analogues thereof 失效
标题翻译：涉及异黄酮及其类似物的组合物和治疗方法
公开(公告)号：US07488494B2
公开(公告)日：2009-02-10
申请号：US10704385
申请日：2003-11-07
申请人： Andrew Heaton , Naresh Kumar , Graham Edmund Kelly , Alan Husband
发明人： Andrew Heaton , Naresh Kumar , Graham Edmund Kelly , Alan Husband
IPC分类号： A61K47/22 , A61K31/47 , C07D335/04 , C07D311/04
CPC分类号： C07D311/26 , A23L33/10 , A23L33/11 , A23V2002/00 , C07D311/36 , C07D311/38 , C07D311/58 , C07D471/06 , A23V2250/2116 , A23V2200/30
摘要： Isoflavone compounds are described and recommended as therapeutic agents. Exemplified and preferred compounds are (a). Indications show compounds have good competitive binding to estrogen receptors. This is exemplified
摘要翻译：描述和推荐异黄酮化合物作为治疗剂。示例性和优选的化合物是（a）。适应症显示化合物与雌激素受体具有良好的竞争性结合。这是例证

17. 发明申请

US20070130616A1 Dynamic constraints for query operations 有权
标题翻译：查询操作的动态约束
公开(公告)号：US20070130616A1
公开(公告)日：2007-06-07
申请号：US11296027
申请日：2005-12-06
申请人： Raymond Ng , Ganesh Kirti , Thomas Keefe , Naresh Kumar
发明人： Raymond Ng , Ganesh Kirti , Thomas Keefe , Naresh Kumar
IPC分类号： H04L9/32
CPC分类号： G06F21/6227 , G06F2221/2105 , G06F2221/2149 , H04L63/168
摘要： Systems, methods, and machine-readable media are disclosed for providing dynamic and/or conditional constraints on queries based on an external security policy. In one embodiment, a method is provided which comprises receiving from a user a request to access a resource. A condition clause can be read from a grant statement defined in the security policy. The grant statement can define permission for the user to access the requested resource. In some cases, the grant statement can comprise a Java Authentication and Authorization Service (JAAS) grant statement. A query associated with the requested access can be modified based on the permission granted to the user. The modified query can then be made to perform the requested access.
摘要翻译：公开了系统，方法和机器可读介质，用于基于外部安全策略来提供关于查询的动态和/或条件约束。在一个实施例中，提供了一种方法，其包括从用户接收访问资源的请求。可以从安全策略中定义的授权语句读取条件子句。授权语句可以定义用户访问所请求资源的权限。在某些情况下，授权语句可以包含Java认证和授权服务（JAAS）授权语句。可以基于授予用户的权限来修改与请求的访问相关联的查询。然后可以使修改的查询执行请求的访问。

18. 发明申请

US20070032666A1 Production of furanones 失效
标题翻译：生产呋喃酮
公开(公告)号：US20070032666A1
公开(公告)日：2007-02-08
申请号：US11414552
申请日：2006-05-01
申请人： Roger Read , Naresh Kumar
发明人： Roger Read , Naresh Kumar
IPC分类号： C07D305/12
CPC分类号： C08F20/00 , A01N43/08 , C07D307/58 , C08F24/00
摘要： The present invention relates to the side chain functionalization of fimbrolides (halogenated 3-alkyl-5-methylene-2(5H)-furanones) and their synthetic analogues, that yields fimbrolides substituted with a halogen, an oxygen or a nitrogen functionality in the alkyl chain, especially fimbrolide alcohols, caboxylate and sulfinate and sulfonate esters, ethers, aldehydes, ketones, acids, amides, nitro derivatives, hydrophobic, hydrophilic and fluorophilic alkyl derivatives and polymers.
摘要翻译：本发明涉及福滨洛尔（卤代3-烷基-5-亚甲基-2（5H） - 呋喃酮）及其合成类似物的侧链官能化，其产生在烷基中被卤素，氧或氮官能团取代的菲莫拉林链，特别是曲芬洛尔醇，卡波西铵和亚磺酸盐和磺酸酯，醚，醛，酮，酸，酰胺，硝基衍生物，疏水性，亲水和氟烷基衍生物和聚合物。

19. 发明申请

US20060106220A1 Compositions and therapeutic methods involving isoflavones and analogues thereof 审中-公开
标题翻译：涉及异黄酮及其类似物的组合物和治疗方法
公开(公告)号：US20060106220A1
公开(公告)日：2006-05-18
申请号：US11300976
申请日：2005-12-14
申请人： Andrew Heaton , Naresh Kumar , Graham Kelly , Alan Husband
发明人： Andrew Heaton , Naresh Kumar , Graham Kelly , Alan Husband
IPC分类号： A61K31/4745 , C07D471/04 , C07D405/02 , C07D409/02 , C07D401/02 , A61K31/4709
CPC分类号： C07D311/26 , A23L33/10 , A23L33/11 , A23V2002/00 , C07D311/36 , C07D311/38 , C07D311/58 , C07D471/06 , A23V2250/2116 , A23V2200/30
摘要： Isoflavone compounds and analogues thereof, compositions containing same and therapeutic methods of treatment involving same are described.
摘要翻译：描述异黄酮化合物及其类似物，含有其的组合物和涉及其的治疗方法。

20. 发明申请

US20050215772A1 Furanone derivatives and methods of making same 审中-公开
标题翻译：呋喃酮衍生物及其制备方法
公开(公告)号：US20050215772A1
公开(公告)日：2005-09-29
申请号：US10525231
申请日：2003-08-19
申请人： Naresh Kumar
发明人： Naresh Kumar
IPC分类号： A01N43/08 , A01N43/36 , A61L2/16 , A61L12/14 , A61P17/10 , A61P31/00 , A61P33/00 , C07D207/38 , C07D207/44 , C07D307/34 , C07D307/60 , C07D307/66 , C07H19/22 , C07D207/24 , C07H19/048
CPC分类号： C07D207/44 , A01N43/08 , A01N43/36 , A61L2/16 , A61L12/14 , C07D207/38 , C07D307/34 , C07D307/60 , C07D307/66
摘要： Novel synthesis methods, to the products of such novel methods, and to uses of these products. In particular, the present invention provides methods for the reactions of furanones, in particular fimbrolides, with amines. The invention has particular application in the synthesis of halogenated 1,5-dihydro-pyrrol-2-one, 5-halomethylene substituted 1,5-dihydropyrrol-2-ones (lactam analogues of fimbriolides), 5-amino substituted furanones and 5-aminomethylene-2(5H)-furanones and their synthetic analogues. The invention also relates to novel compounds and uses thereof.
摘要翻译：新型合成方法，对这些新方法的产品，以及这些产品的用途。特别地，本发明提供了呋喃酮，特别是福滨洛尔与胺反应的方法。本发明特别适用于卤代1,5-二氢 - 吡咯-2-酮，5-卤代亚甲基取代的1,5-二氢吡咯-2-酮（呋喃草醚的内酰胺类似物），5-氨基取代的呋喃酮和5- 氨基亚甲基-2（5H） - 呋喃酮及其合成类似物。本发明还涉及新化合物及其用途。

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