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11. 发明授权

US07084162B2 Substituted acid derivatives useful as antidiabetic and antiobesity agents and method 有权
标题翻译：用作抗糖尿病和抗肥胖剂的取代的酸衍生物和方法
公开(公告)号：US07084162B2
公开(公告)日：2006-08-01
申请号：US10655876
申请日：2003-09-05
申请人： Peter T. Cheng , Pratik Devasthale , Yoon Jeon , Sean Chen , Hao Zhang
发明人： Peter T. Cheng , Pratik Devasthale , Yoon Jeon , Sean Chen , Hao Zhang
IPC分类号： A61K31/421 , C07D263/32
CPC分类号： C07D263/58 , C07D231/12 , C07D233/56 , C07D249/08 , C07D263/32 , C07D277/24 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/12 , C07D495/04
摘要： Compounds are provided which have the structure wherein Q is C or N, A is O or S, Z is O or a bond, X is CH or N and R1, R2, R2a, R2b, R2c, R3, Y, x, m, and n are as defined herein, which compounds are useful as antidiabetic, hypolipidemic, and antiobesity agents.
摘要翻译：提供具有其中Q为C或N，A为O或S，Z为O或键，X为CH或N，R 1，R 2， R 2，R 2b，R 2b，R 2c，R 3，Y，x，m和 n如本文所定义，这些化合物可用作抗糖尿病，降血脂症和抗肥胖剂。

12. 发明授权

US06919358B2 Substituted acid derivatives useful as antidiabetic and antiobesity agents and method 有权
公开(公告)号：US06919358B2
公开(公告)日：2005-07-19
申请号：US10080965
申请日：2002-02-22
申请人： Peter T. Cheng , Pratik Devasthale , Yoon Jeon , Sean Chen , Hao Zhang
发明人： Peter T. Cheng , Pratik Devasthale , Yoon Jeon , Sean Chen , Hao Zhang
IPC分类号： C07D263/32 , C07D263/58 , C07D277/24 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/12 , C07D495/04 , C07D521/00 , A61K31/443
CPC分类号： C07D263/58 , C07D231/12 , C07D233/56 , C07D249/08 , C07D263/32 , C07D277/24 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/12 , C07D495/04
摘要： Compounds are provided which have the structure wherein Q is C or N, A is O or S, Z is O or a bond, X is CH or N and R1, R2, R2a, R2b, R2c, R3, Y, x, m, and n are as defined herein, which compounds are useful as antidiabetic, hypolipidemic, and antiobesity agents.

13. 发明授权

US06875782B2 Substituted heterocyclic derivatives useful as antidiabetic and antiobesity agents and method 有权
标题翻译：用作抗糖尿病和抗肥胖剂的取代的杂环衍生物和方法
公开(公告)号：US06875782B2
公开(公告)日：2005-04-05
申请号：US10616283
申请日：2003-07-08
申请人： Peter T. W. Cheng , Sean Chen , Charles Z. Ding , Timothy F. Herpin
发明人： Peter T. W. Cheng , Sean Chen , Charles Z. Ding , Timothy F. Herpin
IPC分类号： A61K31/41 , A61K31/42 , A61K31/435 , A61K31/50 , A61K31/52 , C07D233/54 , C07D249/06 , C07D263/32 , C07D271/06 , C07D413/12 , A61K31/4245 , A61K31/4192 , C07D249/04
CPC分类号： C07D233/64 , C07D249/06 , C07D263/32 , C07D271/06 , C07D413/12
摘要： Compounds are provided which are useful as antidiabetic agents and antiobesity agents and have the structure wherein m is 0, 1 or 2; n is 0, 1 or 2; Q is C or N; A is (CH2)x where x is 1 to 5, or A is (CH2)x1 where x1 is 1 to 5 with an alkenyl bond or an alkynyl bond embedded anywhere in the chain, or A is —(CH2)x2—O—(CH2)x3— where x2 is 0 to 5 and x3 is 0 to 5, provided that at least one of x2 and x3 is other than 0; B is a bond or is (CH2)x4 where x4 is 1 to 5; X is CH or N; X2 is C, N, O or S; X3 is C, N, O or S; X4 is C, N, O or S; X5 is C, N, O or S; X6 is C, N, O or S; and A, R1, R2, R2a, R2b, R2c, R3 and Y are as defined herein.
摘要翻译：提供了可用作抗糖尿病药和抗肥胖剂并具有其中m为0,1或2的结构的化合物; n为0,1或2; Q为C或N; A为（CH 2）x，其中x为1至5，或A为（CH 2）x 1），其中x 1为具有烯基键的1至5 或嵌入链中任何位置的炔基键，或A是 - （CH 2）x 2 -O-（CH 2）x 3 - ，其中x 2为0至5，x 3为0至5 条件是x 2和x 3中的至少一个不是0; B是键或是（CH 2）x 4，其中x 4是1至5; X是CH或N; X2是C，N，O或S; X 3是C，N，O或S; X 4是C，N，O或S; X 5是C，N，O或S; X 6是C，N，O或S; 并且A，R 1，R 2，R 2a，R 2b，R 2c，R 3和Y如本文所定义。

14. 发明申请

US20140264036A1 Assembling Infrared Touch Control Module 有权
标题翻译：组装红外线触摸控制模块
公开(公告)号：US20140264036A1
公开(公告)日：2014-09-18
申请号：US13845188
申请日：2013-03-18
申请人： Iman Hung , Chien-Ta Lin , Eric Huang , Sean Chen
发明人： Iman Hung , Chien-Ta Lin , Eric Huang , Sean Chen
IPC分类号： G06F3/042
CPC分类号： G06F3/0421
摘要： An assembling infrared touch control module is provided and includes four L-shaped first frame members and a plurality of straight second frame members matched in pairs. Each first and second frame member has a space therein and two openings at two ends thereof, respectively, in communication with the space. Each space has a circuit board therein. Each circuit board has a plurality of infrared transmitter/receiver components thereon and two connectors thereon at the two openings, respectively. The four first frame members and the second frame members whose number may be increased or decreased by demand are assembled together to form a frame by means of the connectors so that an active touch area of the frame may be resized by demand to be adapted to a display device of any size, and an additional touch control function adapted to an extended area for the display device may be set.
摘要翻译：提供组装的红外线触摸控制模块，其包括四个L形的第一框架构件和成对匹配的多个直的第二框架构件。每个第一和第二框架构件在其中分别具有一个空间，两个开口分别与该空间连通。每个空间中都有一个电路板。每个电路板在其上分别具有多个红外发射器/接收器部件和两个连接器。通过需要将数量可以增加或减少的四个第一框架构件和第二框架构件组装在一起以通过连接器形成框架，使得框架的主动触摸区域可以根据需要调整大小以适应于可以设置任何尺寸的显示装置和适于显示装置的扩展区域的附加触摸控制功能。

15. 发明授权

US08789128B2 System and method for recording and time-shifting programming in a television distribution system using policies 有权
标题翻译：在使用策略的电视分配系统中记录和时移节目的系统和方法
公开(公告)号：US08789128B2
公开(公告)日：2014-07-22
申请号：US11316066
申请日：2005-12-21
申请人： Zesen Chen , Peter Chou , Sean Chen , Brian Gonsalves , Donald M. Smith
发明人： Zesen Chen , Peter Chou , Sean Chen , Brian Gonsalves , Donald M. Smith
IPC分类号： H04N7/173 , H04N7/16
CPC分类号： H04N21/4627 , H04N5/76 , H04N7/165 , H04N7/17318 , H04N21/2747 , H04N21/4334 , H04N21/8355
摘要： Various embodiments of the disclosed subject matter provide methods and systems to store a policy specifying at least one rule relating to recording, storage or delivery of broadcast programming to a consumer of such programming, and to record, store or deliver broadcast programming in response to at least one of the rules in the policy. According to another example embodiment, a method and system provide for a subscriber requesting that at least one broadcast television program be saved for the subscriber upstream from the subscriber in a television distribution system, and further that the at least one program offered to the subscriber for saving is determined based on a policy established for the at least program. According to another example embodiment a system provides at least one computing device including a computer program to control the recording or delivery of at least one broadcast television program in accordance with a policy established to control the recording or delivery of the broadcast television program.
摘要翻译：所公开的主题的各种实施例提供方法和系统，用于存储指定关于广播节目的记录，存储或传送的至少一个规则的策略给消费者的这种节目，并且响应于在...而记录，存储或传送广播节目政策中最少的规则之一。根据另一示例实施例，一种方法和系统为用户请求在电视分配系统中为订户上游保留至少一个广播电视节目，并且还向用户提供至少一个节目基于为至少程序建立的策略确定保存。根据另一示例性实施例，系统提供至少一个包括计算机程序的计算设备，该计算机程序根据为控制广播电视节目的记录或传送而建立的策略来控制至少一个广播电视节目的记录或传送。

16. 发明授权

US08474003B2 System and method for recording and time-shifting programming in a television distribution system with limited content retention 有权
标题翻译：在具有有限内容保留的电视分配系统中记录和时移编程的系统和方法
公开(公告)号：US08474003B2
公开(公告)日：2013-06-25
申请号：US13305270
申请日：2011-11-28
申请人： Zesen Chen , Peter Chou , Sean Chen , Brian Gonsalves
发明人： Zesen Chen , Peter Chou , Sean Chen , Brian Gonsalves
IPC分类号： H04N7/173
CPC分类号： H04N21/231 , G06F17/30067 , H04N7/17318 , H04N21/23106 , H04N21/23113 , H04N21/26275 , H04N21/2747 , H04N21/4333 , H04N21/4335 , H04N21/47214 , H04N21/4728
摘要： Various embodiments of the disclosed subject matter provide methods and systems to record broadcast programming for at least one television channel for a period of time, wherein the recording is performed upstream from subscribers in a television distribution system, and further including after the period of time, keeping recorded programming by request from at least one subscriber. And further wherein the request is for at least one television program contained in the recorded programming or for a time window for a particular channel. According to another embodiment a subscriber requests that broadcast programming be saved for the subscriber upstream from the subscriber in a television distribution system, and wherein the subscriber may request the programming be saved for later viewing by the subscriber between the time the programming was broadcast and a later point in time.
摘要翻译：所公开的主题的各种实施例提供用于在一段时间内为至少一个电视频道记录广播节目的方法和系统，其中在电视分配系统中的用户进行记录，并且还包括在一段时间之后，通过来自至少一个订户的请求来保存记录的节目。此外，其中该请求是针对包含在所记录的节目中的至少一个电视节目或针对特定频道的时间窗口。根据另一个实施例，用户请求在电视分配系统中为订户上游节约用户的广播节目，并且其中用户可以在播放节目播放时间和节目播放时间之间请求编程节目以供用户稍后观看稍后的时间点。

17. 发明申请

US20120142636A1 NOVEL GLUCOKINASE ACTIVATORS AND METHODS OF USING SAME 有权
标题翻译：新型GLUCOKINASE激活剂及其使用方法
公开(公告)号：US20120142636A1
公开(公告)日：2012-06-07
申请号：US13397123
申请日：2012-02-15
申请人： Denis E. Ryono , Peter T.W. Cheng , Scott A. Bolton , Sean Chen , Yan Shi , Wei Meng , Joseph A. Tino , Richard B. Sulsky
发明人： Denis E. Ryono , Peter T.W. Cheng , Scott A. Bolton , Sean Chen , Yan Shi , Wei Meng , Joseph A. Tino , Richard B. Sulsky
IPC分类号： A61K31/675 , A61P17/02 , A61P9/10 , A61P9/00 , A61P1/18 , A61P3/04 , A61P3/06 , A61P35/00 , A61P25/00 , A61P31/18 , A61P3/10 , A61P3/00
CPC分类号： C07F9/6539 , C07F9/58 , C07F9/65031 , C07F9/650952 , C07F9/6518
摘要： Compounds are provided which are phosphonate and phosphinate activators and thus are useful in treating diabetes and related diseases and have the structure is a heteroaryl ring; R4 is —(CH2)n—Z—(CH2)m—PO(OR7)(OR8), —(CH2)nZ—(CH2)m—PO(OR7)R9, —(CH2)n—Z—(CH2)m—OPO(OR7)R9, —(CH2)nZ—(CH2)m—OPO(R9)(R10), or —(CH2)nZ—(CH2)m—PO(R9)(R10); R5 and R6 are independently selected from H, alkyl and halogen; Y is R7(CH2)s or is absent; and X, n, Z, m, R4, R5, R6, R7, and s are as defined herein; or a pharmaceutically acceptable salt thereof. A method for treating diabetes and related diseases employing the above compounds is also provided.
摘要翻译：提供了膦酸酯和次膦酸酯活化剂的化合物，因此可用于治疗糖尿病和相关疾病，并且其结构是杂芳基环; R4是 - （CH2）n-Z-（CH2）m-PO（OR7）（OR8）， - （CH2）nZ-（CH2）m-PO（OR7）R9， - （CH2）n-Z- ）m-OPO（OR 7）R 9， - （CH 2）n Z-（CH 2）m -OPO（R 9）（R 10）或 - （CH 2）n Z-（CH 2）m -PO（R 9）（R 10） R5和R6独立地选自H，烷基和卤素; Y为R 7（CH 2）s或不存在; 并且X，n，Z，m，R 4，R 5，R 6，R 7和s如本文所定义; 或其药学上可接受的盐。还提供了使用上述化合物治疗糖尿病和相关疾病的方法。

18. 发明授权

US07983176B2 Method and system for monitoring communications of an individual in a packet network 有权
标题翻译：用于监视分组网络中的个体的通信的方法和系统
公开(公告)号：US07983176B2
公开(公告)日：2011-07-19
申请号：US11228134
申请日：2005-09-16
申请人： Zesen Chen , Peter Chou , Sean Chen , Yongdong Zhao
发明人： Zesen Chen , Peter Chou , Sean Chen , Yongdong Zhao
IPC分类号： H04J3/14
CPC分类号： H04M7/006 , H04L41/0213 , H04L43/00 , H04M3/2281
摘要： A system and method are disclosed for monitoring communications of an individual in a packet network. A system that incorporates teachings of the present disclosure may include, for example, a network monitor having a communications interface coupled to a packet network, and a controller. The controller can be programmed to receive a request from a third party to monitor communications associated with an individual, convey to the third party information monitored on a group of one or more permanent virtual circuits (PVCs) of the packet network associated with the individual, detect an update in the group of one or more PVCs, determine new set of one or more PVCs associated with the individual, and convey to the third party information monitored from the new set of one or more PVCs.
摘要翻译：公开了一种用于监视分组网络中的个人的通信的系统和方法。结合本公开的教导的系统可以包括例如具有耦合到分组网络的通信接口的网络监视器和控制器。控制器可以被编程为接收来自第三方的请求以监视与个人相关联的通信，将与个人相关联的分组网络的一组或多个永久虚拟电路（PVC）的组中监视的信息传达给第三方信息，检测一个或多个PVC组中的更新，确定与个体相关联的一组或多个PVC的新集合，并将新信息传达给第三方信息。

19. 发明授权

US07951793B2 Substituted heterocyclic derivatives useful as antidiabetic and antiobesity agents and method 有权
标题翻译：用作抗糖尿病和抗肥胖剂的取代的杂环衍生物和方法
公开(公告)号：US07951793B2
公开(公告)日：2011-05-31
申请号：US11779319
申请日：2007-07-18
申请人： Peter T. W. Cheng , Sean Chen , Pratik Devasthale , Charles Z. Ding , Timothy F. Herpin , Shung Wu , Hao Zhang , Wei Wang , Xiang-Yang Ye
发明人： Peter T. W. Cheng , Sean Chen , Pratik Devasthale , Charles Z. Ding , Timothy F. Herpin , Shung Wu , Hao Zhang , Wei Wang , Xiang-Yang Ye
IPC分类号： A61K31/397 , C07D205/08 , A01N43/00
CPC分类号： C07D413/12 , C07D413/14
摘要： Compounds are provided which have the structure wherein Z1 is (CH2)q or C═O; Z2 is (CH2)p or C═O; D is —CH═ or C═O or (CH2)m where m is 0, 1, 2 or 3; n=0, 1 or 2; p=1 or 2; q=0, 1 or 2; Q is C or N; X is CH or N; X2 is C, N, O or S; X3 is C, N, O or S; X4 is C, N, O or S; X5 is C, N, O or S; X6 is C, N, O or S; provided that at least one of X2, X3, X4 X5 and X6 is N; and at least one of X2, X3, X4 X5 and X6 is C; and A, B, R1, R2, R2a, R4, R3, E, Z and Y are as defined herein, which compounds are useful in treating diabetes and related diseases.
摘要翻译：提供具有其中Z 1是（CH 2）q或C = O的结构的化合物; Z2是（CH2）p或C = O; D是-CH =或C = O或（CH 2）m，其中m为0,1,2或3; n = 0,1或2; p = 1或2; q = 0,1或2; Q是C或N; X是CH或N; X2是C，N，O或S; X3为C，N，O或S; X4为C，N，O或S; X5为C，N，O或S; X6为C，N，O或S; 条件是X 2，X 3，X 4 X 5和X 6中的至少一个为N; X2，X3，X4，X5和X6中的至少一个为C; 并且A，B，R1，R2，R2a，R4，R3，E，Z和Y如本文所定义，该化合物可用于治疗糖尿病和相关疾病。

20. 发明申请

US20110118211A1 NOVEL GLUCOKINASE ACTIVATORS AND METHODS OF USING SAME 有权
标题翻译：新型GLUCOKINASE激活剂及其使用方法
公开(公告)号：US20110118211A1
公开(公告)日：2011-05-19
申请号：US13012351
申请日：2011-01-24
申请人： Denis E. Ryono , Peter T.W. Cheng , Scott A. Bolton , Sean Chen , Yan Shi , Wei Meng , Joseph A. Tino , Richard B. Sulsky
发明人： Denis E. Ryono , Peter T.W. Cheng , Scott A. Bolton , Sean Chen , Yan Shi , Wei Meng , Joseph A. Tino , Richard B. Sulsky
IPC分类号： A61K31/675 , C07F9/6503 , A61K31/683 , C07F9/6558 , A61P3/10 , A61P27/02 , A61P17/02 , A61P9/10 , A61P9/00 , A61P3/04 , A61P9/12 , A61P3/06 , A61P35/00 , A61P19/08
CPC分类号： C07F9/6539 , C07F9/58 , C07F9/65031 , C07F9/650952 , C07F9/6518
摘要： Compounds are provided which are phosphonate and phosphinate activators and thus are useful in treating diabetes and related diseases and have the structure wherein is a heteroaryl ring; R4 is —(CH2)n—Z—(CH2)mPO(OR7)(OR8), —(CH2)nZ—(CH2)m—PO(OR7)R9, —(CH2)n—Z—(CH2)m—OPO(OR7)R9, —(CH2)nZ—(CH2)m—OPO(R9)(R10), or —(CH2)nZ—(CH2)m—PO(R9)(R10); R5 and R6 are independently selected from H, alkyl and halogen; Y is R7(CH2)s or is absent; and X, n, Z, m, R4, R5, R6, R7, and s are as defined herein; or a pharmaceutically acceptable salt thereof. A method for treating diabetes and related diseases employing the above compounds is also provided.
摘要翻译：提供了膦酸酯和次膦酸酯活化剂的化合物，因此可用于治疗糖尿病和相关疾病，并且其结构是杂芳基环; R4是 - （CH2）n-Z-（CH2）mPO（OR7）（OR8）， - （CH2）nZ-（CH2）m-PO（OR7）R9， - （CH2）n-Z-（CH2） -OPO（OR 7）R 9， - （CH 2）n Z-（CH 2）m -OPO（R 9）（R 10）或 - （CH 2）n Z-（CH 2）m -PO（R 9）（R 10） R5和R6独立地选自H，烷基和卤素; Y为R 7（CH 2）s或不存在; 并且X，n，Z，m，R 4，R 5，R 6，R 7和s如本文所定义; 或其药学上可接受的盐。还提供了使用上述化合物治疗糖尿病和相关疾病的方法。

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