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11. 发明申请

WO2008087415A2 REVERSE SHOULDER PROSTHESIS 审中-公开
标题翻译：反向肩膀PROSTHESIS
公开(公告)号：WO2008087415A2
公开(公告)日：2008-07-24
申请号：PCT/GB2008000154
申请日：2008-01-17
申请人： UNIV NEWCASTLE , JOHNSON GARTH , KONTAXIS ANDREAS , WALLACE ANGUS
发明人： JOHNSON GARTH , KONTAXIS ANDREAS , WALLACE ANGUS
IPC分类号： A61F2/40
CPC分类号： A61F2/40 , A61B17/86 , A61F2/4014 , A61F2/4081 , A61F2002/30125 , A61F2002/30224 , A61F2002/30245 , A61F2002/30355 , A61F2002/30433 , A61F2002/30772 , A61F2002/30878 , A61F2002/30884 , A61F2002/30934 , A61F2002/4085 , A61F2220/0033 , A61F2220/0041 , A61F2230/0008 , A61F2230/0069 , A61F2230/0071 , A61F2310/00011
摘要： A scapula component for a reverse shoulder prosthesis comprises a part spherical, convex, surface which is less than a hemisphere. The part spherical surface does not have a rotational axis of symmetry, and may include a main circular surface portion (3) and one or more subsidiary surface portions (5, 6, 7) depending from an edge of the main surface portion.
摘要翻译：用于逆肩假体的肩胛骨部件包括小于半球的部分球形，凸形表面。部分球面不具有旋转对称轴线，并且可以包括主圆形表面部分（3）和从主表面部分的边缘悬垂的一个或多个辅助表面部分（5,6,7）。

12. 发明申请

WO2008012578A2 BIOREMEDIATION METHOD 审中-公开
标题翻译：生物化学方法
公开(公告)号：WO2008012578A2
公开(公告)日：2008-01-31
申请号：PCT/GB2007050438
申请日：2007-07-24
申请人： UNIV NEWCASTLE , JONES MARTIN , WERNER DAVID , SINGLETON IAN
发明人： JONES MARTIN , WERNER DAVID , SINGLETON IAN
IPC分类号： B09C1/10
CPC分类号： B09C1/10
摘要： A method for treating soil contaminated with at least one pollutant comprises the steps of mixing the soil with biodiesel and nutrients, forming the mixture into heaps and leaving the mixture for up to twelve months. The pollutant is typically a polycyclic aromatic hydrocarbon.
摘要翻译：用于处理被至少一种污染物污染的土壤的方法包括将土壤与生物柴油和营养物混合的步骤，将混合物混合成堆并将混合物离开长达十二个月。污染物通常是多环芳烃。

13. 发明申请

WO9741150A3 GENE THERAPY FOR MITOCHONDRIAL DNA DEFECTS USING PEPTIDE NUCLEIC ACIDS 审中-公开
标题翻译：使用肽核酸对遗传性DNA缺陷进行基因治疗
公开(公告)号：WO9741150A3
公开(公告)日：1997-12-04
申请号：PCT/GB9701102
申请日：1997-04-22
申请人： UNIV NEWCASTLE , TURNBULL DOUGLAS MATTHEW , LIGHTOWLERS ROBERT NEIL , TAYLOR ROBERT WILLIAM
发明人： TURNBULL DOUGLAS MATTHEW , LIGHTOWLERS ROBERT NEIL , TAYLOR ROBERT WILLIAM
IPC分类号： A61K38/00 , A61K48/00 , C07K14/00 , C07K14/47 , C12N9/02
CPC分类号： C12N9/0053 , A61K38/00 , A61K48/00 , C07K14/003 , C07K14/47
摘要： The invention concerns a method for selectively preventing the replication of mitochondrial DNA using complementary peptide nucleic acids; and the peptide nucleic acids for use in the method. Additionally novel targeting means are described for ensuring the targeting of the peptide nucleic acids into mitochondria.

14. 发明申请

WO2015075467A2 MODEL GUT SYSTEM 审中-公开
标题翻译： MODEL GUT系统
公开(公告)号：WO2015075467A2
公开(公告)日：2015-05-28
申请号：PCT/GB2014053449
申请日：2014-11-21
申请人： UNIV NEWCASTLE
发明人： PEARSON JEFF , BROWNLEE IAIN , WILCOX MATT , CHATER PETER
IPC分类号： G01N33/50
CPC分类号： G01N33/66 , C12N9/94 , C12Q1/37 , C12Q1/40 , C12Q1/44 , G01N33/68 , G01N33/92 , G09B9/00 , G09B23/30 , G09B23/303 , G09B23/306
摘要： The invention relates to a Mode! Gut System (MGS) comprising a pancreatic phase consisting essentially of synthetic pancreatic juice comprising pancreatin and one or more suitable pancreatic diluent(s) at a pH from about 7 to about 9, preferably about 7.9 to about 8.2, and porcine bile.
摘要翻译：本发明涉及一种模式！肠系统（MGS）包括基本上由合成胰液组成的胰酶，胰蛋白酶包含胰蛋白酶和一种或多种合适的胰液稀释液，pH约为7至约9，优选约7.9至约8.2，以及猪胆汁。

15. 发明申请

WO2010040996A2 SYNTHETIC SYMBIOTIC SYSTEM AS SOIL ADDITIVES TO DELIVER ACTIVE INGREDIENTS THROUGH PLANT ROOTS FOR ENHANCED PLANT AND CROP YIELD 审中-公开
标题翻译：合成符号系统作为土壤添加剂，通过植物种植提供活性成分，用于增强植物和作物产量
公开(公告)号：WO2010040996A2
公开(公告)日：2010-04-15
申请号：PCT/GB2009002380
申请日：2009-10-06
申请人： UNIV NEWCASTLE , AKAY GALIP , BURKE DAVID ROBERT
发明人： AKAY GALIP , BURKE DAVID ROBERT
IPC分类号： A61L27/16 , A61L27/18 , A61L27/20 , A61L27/22 , A61L27/56 , C08F2/24
CPC分类号： A01H3/00 , Y10T428/249921
摘要： A plant growth support medium is described to enhance soil characteristics and provide where required, improved water, or nutrient contents. La addition the medium can be inoculated with microorganisms to aid soil characteristics and provide interactions within micron-scale environment between plant roots, water, nutrients and where applicable, bacteria and root exudates. This micro-environment provides direct delivery of active ingredients to the plant roots. The medium comprises a polymeric material having a primary pore size of greater than 30 micron. The walls of the pores are elastic, enabling the pore to swell in size to retain water, solutes or other biologically useful components and allow root penetration through them. Sulphonation of the walls renders the walls more hydrophilic so attracting water into the pores and also increasing the wall elasticity. Capillaries can be provided to interconnect pores and allow root penetration into the medium. The pore walls can be granular in character to allow water, nutrient and where applicable, bacterial metabolites and messenger molecules passage between adjacent pores and plant roots.
摘要翻译：描述植物生长支持培养基以增强土壤特性，并在需要的地方提供改善的水或营养物质。 La添加可以用微生物接种培养基以帮助土壤特性，并在植物根，水，营养物之间以及适用的细菌和根系分泌物的微米级环境中提供相互作用。这种微环境提供活性成分直接递送到植物根部。介质包括主孔径大于30微米的聚合材料。孔的壁是弹性的，使得孔的尺寸膨胀以保持水，溶质或其他生物有用的组分并允许根穿透它们。壁的磺化使得壁更亲水，从而将水吸引到孔中并且还增加壁弹性。可以提供毛细管以连接孔隙并允许根部穿透到介质中。孔壁可以是粒状的，以允许水，营养物质和适用的细菌代谢物和信使分子在相邻的孔和植物根之间通过。

16. 发明申请

WO2008064413A1 PLANTS WITH HEXOSE ACCUMULATING TISSUES HAVING AN ALTERED HEXOSE CONCENTRATION 审中-公开
标题翻译：含有HEXOSE含有改变的HEXOSE浓度的累积组织的植物
公开(公告)号：WO2008064413A1
公开(公告)日：2008-06-05
申请号：PCT/AU2007001827
申请日：2007-11-28
申请人： UNIV NEWCASTLE RES ASS , DIBLEY STEPHEN JAMES , MCCURDY DAVID WILLIAM , PATRICK JOHN WILLIAM
发明人： DIBLEY STEPHEN JAMES , MCCURDY DAVID WILLIAM , PATRICK JOHN WILLIAM
IPC分类号： A01H3/00 , A01H1/00 , A01H5/00
CPC分类号： A01H1/04 , C07K14/415 , C12N15/8245 , C12N15/8271
摘要： The invention relates to plants having an altered hexose concentration in hexose accumulating tissue (e.g., fruit) of the plant. The invention also relates to methods for providing such plants.
摘要翻译：本发明涉及在植物的己糖聚集组织（例如果实）中具有改变的己糖浓度的植物。本发明还涉及提供这种植物的方法。

17. 发明申请

WO2007007052A2 IMMOBILISATION OF BIOLOGICAL MOLECULES 审中-公开
标题翻译：生物分子的免疫
公开(公告)号：WO2007007052A2
公开(公告)日：2007-01-18
申请号：PCT/GB2006002510
申请日：2006-07-06
申请人： UNIV NEWCASTLE , SUAREZ GUILLAUME
发明人： SUAREZ GUILLAUME
IPC分类号： G01N33/50 , G01N33/543
CPC分类号： B82Y30/00 , G01N33/54353 , G01N33/5436 , G01N33/54373
摘要： A method of immobilising a biological molecule on a substrate comprises: (i) covalently attaching a substantially three-dimensional polysilane polymer to a substrate; and (ii) attaching a biological molecule onto and/or within the polymer. The method may additionally comprise the steps of coating the substrate (or the chemically protective layer) with a layer of radiation sensitive material, exposing the substrate to a source of radiation, and incubating the substrate in the presence of a first species of biological molecule.
摘要翻译：将生物分子固定在基材上的方法包括：（i）将基本上三维的聚硅烷聚合物共价连接到基材上; 和（ii）将生物分子附着在聚合物上和/或聚合物内。该方法可以另外包括以下步骤：用辐射敏感材料层涂覆基底（或化学保护层），将基底暴露于辐射源，并在第一种生物分子的存在下孵育底物。

18. 发明申请

WO03093535A2 ELECTROLYSIS CELL AND METHOD 审中-公开
标题翻译：电解槽和方法
公开(公告)号：WO03093535A2
公开(公告)日：2003-11-13
申请号：PCT/GB0301786
申请日：2003-04-28
申请人： UNIV NEWCASTLE VENTURES LTD , CHRISTENSEN PAUL ANDREW , SCOTT KEITH
发明人： CHRISTENSEN PAUL ANDREW , SCOTT KEITH
IPC分类号： C02F1/461 , C25B
CPC分类号： C02F1/46104 , C02F1/46109 , C02F2001/46142 , C02F2001/46166 , C02F2101/163 , C02F2101/36 , C02F2201/46115 , C02F2201/46195
摘要： A zero-gap solid polymer electrolyte electrolysis cell is provided comprising an anode; a cathode; and an ion exchange membrane disposed between the anode and the cathode; wherein the cathode is a catalyst comprising a hydrogen sorbing material. This cell can be used in the dehalogenation of halogenated organic compounds and the destruction of aqueous nitrates.
摘要翻译：提供了一种零间隙固体聚合物电解质电解池，包括阳极; 阴极以及设置在阳极和阴极之间的离子交换膜; 其中所述阴极是包含吸氢材料的催化剂。该电池可用于卤代有机化合物的脱卤和硝酸盐水溶液的破坏。

19. 发明申请

WO03057708A2 FUSION PROTEINS 审中-公开
标题翻译：融合蛋白
公开(公告)号：WO03057708A2
公开(公告)日：2003-07-17
申请号：PCT/GB0300078
申请日：2003-01-10
申请人： UNIV NEWCASTLE VENTURES LTD , GOKCE ISA , ANDERLUH GREGOR , LAKEY JEREMY HUGH
发明人： GOKCE ISA , ANDERLUH GREGOR , LAKEY JEREMY HUGH
IPC分类号： C12N15/09 , C07K14/245 , C07K14/47 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C07K
CPC分类号： C07K14/245 , C07K2319/00
摘要： The present invention relates to fusion proteins (fusion polypeptides), particularly for use in expression and/or purification systems. The present inventors have found that the To1AIII domain has remarkable properties which are of particular use as a fusion protein partner to achieve high levels of expression in a host cell. In one aspect of the invention, a To1AIII domain or a functional homologue, fragment, or derivative thereof is located towards the N−terminus of the fusion polypeptide and a non−To1A polypeptide is located towards the C−terminus of the fusion polypeptide.
摘要翻译：本发明涉及融合蛋白（融合多肽），特别是用于表达和/或纯化系统。本发明人已经发现，To1AIII结构域具有特别用作融合蛋白配偶体以在宿主细胞中实现高水平表达的显着性质。在本发明的一个方面，To1AIII结构域或其功能同系物，片段或衍生物位于融合多肽的N末端，非To1A多肽位于融合多肽的C末端。

20. 发明申请

WO02063264A3 RESONANT SENSOR 审中-公开
标题翻译：谐振传感器
公开(公告)号：WO02063264A3
公开(公告)日：2003-03-20
申请号：PCT/GB0200237
申请日：2002-01-21
申请人： UNIV NEWCASTLE VENTURES LTD , BURDESS JAMES STONEHOUSE , MCNEIL CALUM JACK
发明人： BURDESS JAMES STONEHOUSE , MCNEIL CALUM JACK
IPC分类号： G01G3/16 , G01M3/16 , G01N5/02 , G01N29/02 , G01N29/036 , G01N29/12
CPC分类号： G01N29/12 , G01M3/16 , G01N29/022 , G01N29/036 , G01N2291/014 , G01N2291/0255 , G01N2291/0256 , G01N2291/101
摘要： A resonant sensor for determining structural property changes, in particular for detecting the presence of chemical or biological species, comprises a structure (2) mounted to be capable of resonating and having a cyclically symmetrical configuration with two independent degenerative modes of vibration of a common natural frequency (f), and means (24,26,28,30,32,34,36,38) for exciting the structure (2) to resonate according to the two degenerative modes, regions (8,12,16,20) of the structure (2) being modified such that, on changes in the structural properties of the modified regions (8,12,16,20), for example by the addition or subtraction of mass, the natural frequencies (f1, f2) of the two modes of vibration become different, the difference in frequencies (?f) being proportional to the change in structural properties.
摘要翻译：用于确定结构特性变化的谐振传感器，特别是用于检测化学或生物物质的存在，包括安装成能够谐振并具有周期性对称构型的结构（2），其具有两种独立的退化模式的共同天然频率（f）和用于激励结构（2）根据两个退化模式共振的装置（24,26,28,30,32,34,36,38），区域（8,12,16,20）所述结构（2）被修改为使得在修改的区域（8,12,16,20）的结构特性的改变上，例如通过加或减质量，固有频率（f1，f2）为两种振动模式变得不同，频率差（Δf）与结构特性的变化成正比。

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