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11. 发明授权

US4125611A 3-Heterocyclic thiomethyl 7-methoxy-7 substituted acetamido cephalosporins 失效
标题翻译： 3-杂环硫甲基7-甲氧基-7取代的乙酰氨基头孢菌素
公开(公告)号：US4125611A
公开(公告)日：1978-11-14
申请号：US745749
申请日：1976-11-29
申请人： Hirotada Yamade , Takenari Nakagome , Toshiaki Komatsu
发明人： Hirotada Yamade , Takenari Nakagome , Toshiaki Komatsu
IPC分类号： A61K20060101 , A61K31/545 , A61K31/546 , A61P31/04 , C07D20060101 , C07D501/04 , C07D501/06 , C07D501/20 , C07D501/24 , C07D501/28 , C07D501/32 , C07D501/34 , C07D501/36 , C07D501/40 , C07D501/44 , C07D501/46 , C07D501/56 , C07D501/57 , C07D501/60 , C07D519/06
CPC分类号： C07D501/57 , Y02P20/55
摘要： A cephalosporin of the formula (I): ##STR1## wherein A is a mono- or polycyclic heteroaromatic ring containing at least one nitrogen atom as a hetero atom, which may be unsubstituted or substituted; R is a phenyl group which may be unsubstituted or substituted, a thienyl group, a furyl group, a cyclohexadienyl group or a cyclohexenyl group; X is an acetoxy group, a pyridinium group which may be unsubstituted or substituted with a methyl or carbamoyl group, a group of the formula: ##STR2## in which R.sub.1 and R.sub.2, which may be the same or different, each is a hydrogen atom or a (C.sub.1 - C.sub.4) alkyl group, or a group of the formula:-S-Hetin which Het is a heterocyclic ring containing 1 to 5 oxygen, nitrogen and sulfur atoms as a hetero atom, in which the heterocyclic ring system may be either polycyclic or 5- or 6-membered monocyclic and may be unsubstituted or substituted; and M is a hydrogen atom or a biologically active carboxyl-protecting group, or is an anionic charge only when X is a pyridinium group; and the pharmaceutically acceptable salts thereof, which are useful as antimicrobial agents and prepared by the reaction of a compound of the formula (II):ho--a--cooh (ii)wherein A is as defined above, or a reactive derivative thereof, with a compound of the formula (III): ##STR3## wherein R, M and X are as defined above, or a derivative thereof.
摘要翻译：式（I）的头孢菌素：其中A是含有至少一个氮原子作为杂原子的单环或多环杂芳环，其可以是未取代的或取代的; R是可以是未取代或取代的苯基，噻吩基，呋喃基，环己二烯基或环己烯基; X是乙酰氧基，可以是未取代的或被甲基或氨基甲酰基取代的吡啶鎓基，下式的基团：其中R 1和R 2可以相同或不同，各自为氢原子或（C 1 -C 4）烷基，或下式的基团：

12. 发明授权

US4008237A 2,3,5,8-Tetrahydro-5-alkoxy-8-oxofuro(2,3-g)quinoline-7-carboxylic acid derivatives 失效
标题翻译： 2,3,5,8-四氢-5-烷氧基-8-氧代呋喃（2,3-g）喹啉-7-羧酸衍生物
公开(公告)号：US4008237A
公开(公告)日：1977-02-15
申请号：US626001
申请日：1975-10-28
申请人： Hideo Agui , Iwao Nakatsuka , Toru Mitani , Mitsuo Nakashita , Takenari Nakagome , Toshiaki Komatsu , Akio Izawa , Yasuko Eda
发明人： Hideo Agui , Iwao Nakatsuka , Toru Mitani , Mitsuo Nakashita , Takenari Nakagome , Toshiaki Komatsu , Akio Izawa , Yasuko Eda
IPC分类号： C07D215/56 , C07D491/048
CPC分类号： C07D491/048
摘要： Novel antibacterial agents consisting of a 2,3,5,8-tetrahydro-5-alkoxy-8-oxofuro(2,3-g)quinoline-7-carboxylic acid of the formula: ##STR1## wherein R is C.sub.1 -C.sub.4 alkyl, a process for producing the derivatives and pharmaceutical compositions containing the same. The above-identified derivatives possess antibacterial activity against gram-negative bacteria at test concentration levels of about 0.0001 to 1.0 mg/cc.
摘要翻译：新型抗菌剂由下列通式的2,3,5,8-四氢-5-烷氧基-8-氧代呋喃（2,3-g）喹啉-7-羧酸组成，其中R是C 1 -C 4烷基，制备衍生物的方法和含有该衍生物的药物组合物。上述衍生物在约0.0001至1.0mg / cc的测试浓度水平下对革兰氏阴性细菌具有抗菌活性。

13. 发明授权

US3954775A Thiazolo(5,4-f)quinoline-8-carboxylic acid derivatives 失效
标题翻译：噻唑（5,4-f）喹啉-8-羧酸衍生物
公开(公告)号：US3954775A
公开(公告)日：1976-05-04
申请号：US515753
申请日：1974-10-17
申请人： Hideo Agui , Toru Mitani , Mitsuo Nakashita , Eiichi Murayama , Kousaku Okamura , Takenari Nakagome , Toshiaki Komatsu , Akio Izawa , Yasuko Eda
发明人： Hideo Agui , Toru Mitani , Mitsuo Nakashita , Eiichi Murayama , Kousaku Okamura , Takenari Nakagome , Toshiaki Komatsu , Akio Izawa , Yasuko Eda
IPC分类号： C07D513/04
CPC分类号： C07D513/04
摘要： Thiazolo[5,4-f]quinoline-8-carboxylic acid derivatives having either the general formula (I): ##SPC1##wherein R.sub.1 is a lower alkyl group, a lower alkenyl group or a benzyl group; or the general formula (III-a): ##SPC2##Wherein R.sub.3 is a lower alkyl group and X is a halogen atom; and methods for the preparation thereof. The compounds of the general formula (I) are useful as antibacterial agents against gram-negative and gram-positive bacteria. The compounds of the general formula (III-a) are useful as antifungal agents against eumycetes and also as an intermediate in a preparation of the compounds of the general formula (I).
摘要翻译：具有通式（I）的噻唑并[5,4-f]喹啉-8-羧酸衍生物：

14. 发明授权

US08287417B2 Differential device for vehicle 有权
标题翻译：车辆差速装置
公开(公告)号：US08287417B2
公开(公告)日：2012-10-16
申请号：US11825020
申请日：2007-07-03
申请人： Noriyuki Sudou , Toshiaki Komatsu
发明人： Noriyuki Sudou , Toshiaki Komatsu
IPC分类号： F16H48/20
CPC分类号： F16H48/30 , F16H48/08 , F16H48/24 , F16H48/34 , F16H2048/204 , F16H2048/346 , F16H2048/382
摘要： A differential device for a vehicle includes a differential casing 15, pinion shafts 25, 27 connected to through-holes of the differential casing 15, pinion gears 3 supported by the pinion shafts 25, 27, a differential mechanism 9 having side gears 5, 7 meshing with the pinion gears 3, a limited-slip differential 11 for limiting a differential rotation of the differential mechanism 9 and an actuator 13 for controlling the limited-slip differential 11. A ring gear is fixed on a flange part 17 of the differential casing 15. The flange part 17 is positioned on one side of the differential casing 15 in an axial direction of the differential casing disproportionately. The actuator 13 is arranged so as to abut on the flange part 17. The differential casing 15 is divided into casing pieces by a parting part 19 on one side of the differential casing 15 in opposition to the flange part 17 in the axial direction. The casing pieces are connected with each other by connecting members 21.
摘要翻译：用于车辆的差动装置包括差速器壳体15，连接到差速器壳体15的通孔的小齿轮轴25,27，由小齿轮轴25,27支撑的小齿轮3，具有侧齿轮5,7的差动机构9 与小齿轮3啮合，用于限制差速机构9的差速旋转的限滑差速器11和用于控制限滑差速器11的致动器13.齿圈固定在差速器壳体的凸缘部17上凸缘部分17在差速器壳体15的轴向方向上不均衡地定位在差速器壳体15的一侧上。致动器13被布置成邻接凸缘部17.差速器壳体15通过在差速器壳体15的与轴向方向上相对的凸缘部17的一侧上的分离部分19分成壳体件。壳体通过连接构件21彼此连接。

15. 发明申请

US20110105264A1 CLUTCH DEVICE 有权
标题翻译：离合器件
公开(公告)号：US20110105264A1
公开(公告)日：2011-05-05
申请号：US12917272
申请日：2010-11-01
申请人： Atsushi MARUYAMA , Toshiaki Komatsu , Noriyuki Sudou , Masaaki Fusegi , Hiroyasu Furukawa
发明人： Atsushi MARUYAMA , Toshiaki Komatsu , Noriyuki Sudou , Masaaki Fusegi , Hiroyasu Furukawa
IPC分类号： F16H48/24 , F16D11/04 , F16H48/06
CPC分类号： F16H48/30 , F16D27/118 , F16D2300/12 , F16H48/08 , F16H48/24 , F16H2048/346
摘要： A clutch device is used in combination with a differential device. The clutch device is comprised of: a clutch housed in and rotatable with the differential device and axially movable from a disengaged state into an engaged state; a plunger slidably fit on the differential device and being axially movable from a first position where the plunger does not force the clutch to a second position where the plunger forces the clutch into the engaged state; an anti-rotated solenoid configured to drive the plunger; and a retainer supported by the differential device and in contact with both the plunger at the first position and the solenoid, whereby the plunger is barred from going beyond the first position and the solenoid is axially positioned in place.
摘要翻译：离合器装置与差动装置结合使用。离合器装置包括：离合器，其容纳在差速装置中并且可与该差速装置一起旋转并且可以从分离状态轴向移动到接合状态; 柱塞可滑动地装配在差速装置上并且可从第一位置轴向移动，其中柱塞不迫使离合器到第二位置，在第二位置，柱塞迫使离合器进入接合状态; 构造成驱动柱塞的反旋转螺线管; 以及由所述差速装置支撑并且与所述第一位置处的所述柱塞和所述螺线管接触的保持器，由此所述柱塞被禁止超过所述第一位置，并且所述螺线管被轴向定位就位。

16. 发明申请

US20060044732A1 MULTILAYER CERAMIC CONDENSER 有权
标题翻译：多层陶瓷冷凝器
公开(公告)号：US20060044732A1
公开(公告)日：2006-03-02
申请号：US11204115
申请日：2005-08-16
申请人： Michihisa Shimizu , Kazunori Ito , Toshiaki Komatsu
发明人： Michihisa Shimizu , Kazunori Ito , Toshiaki Komatsu
IPC分类号： H01G4/005
CPC分类号： H01G4/30 , H01G4/012 , H01G4/06 , H01G4/18
摘要： A multilayer ceramic condenser comprises a multilayer body constituted by a plurality of dielectric layers laminated together, first and second terminal electrodes respectively positioned on opposite side faces of the multilayer body, and a plurality of inner electrode groups provided within the multilayer body in a laminating direction of the multilayer body. Each inner electrode group includes a first inner electrode connected to the first terminal electrode, a second inner electrode connected to the second terminal electrode, and a third inner electrode connected to none of the first and second terminal electrodes. The first, second, and third inner electrodes are arranged so as to hold the dielectric layer therebetween such that a plurality of capacitors connected in series are formed between the first and second inner electrodes. The number of capacitors formed in the outermost inner electrode group in the laminating direction of the multilayer body is greater than the number of capacitors formed in the inner electrode group positioned on the inner side of the outermost inner electrode group.
摘要翻译：多层陶瓷电容器包括由层叠在一起的多个电介质层构成的多层体，分别位于多层体的相对侧面的第一和第二端子电极以及层叠方向设置在多层体内的多个内部电极组的多层体。每个内部电极组包括连接到第一端子电极的第一内部电极，连接到第二端子电极的第二内部电极和连接到第一和第二端子电极的第三内部电极。第一，第二和第三内部电极被布置成将介电层保持在其间，使得在第一和第二内部电极之间形成串联连接的多个电容器。在多层体的层叠方向的最外侧的内部电极组中形成的电容器的数量大于位于最外侧的内部电极组的内侧的内部电极组中形成的电容器的数量。

17. 发明授权

US4226863A 7-Methoxy cephalosporins 失效
标题翻译： 7-甲氧基头孢菌素
公开(公告)号：US4226863A
公开(公告)日：1980-10-07
申请号：US937626
申请日：1978-08-25
申请人： Hirotada Yamada , Takenari Nakagome , Toshiaki Komatsu
发明人： Hirotada Yamada , Takenari Nakagome , Toshiaki Komatsu
IPC分类号： A61K20060101 , A61K31/545 , A61K31/546 , A61P31/04 , C07D20060101 , C07D501/04 , C07D501/06 , C07D501/20 , C07D501/24 , C07D501/28 , C07D501/32 , C07D501/34 , C07D501/36 , C07D501/40 , C07D501/44 , C07D501/46 , C07D501/56 , C07D501/57 , C07D501/60 , C07D519/06
CPC分类号： C07D501/57 , Y02P20/55
摘要： A cephalosporin of the formula (I): ##STR1## wherein A is a mono- or polycyclic heteroaromatic ring containing at least one nitrogen atom as a hetero atom, which may be unsubstituted or substituted; R is a phenyl group which may be unsubstituted or substituted, a thienyl group, a furyl group, a cyclohexadienyl group or a cyclohexenyl group; X is an acetoxy group, a pyridinium group which may be unsubstituted or substituted with a methyl or carbamoyl group, a group of the formula: ##STR2## in which R.sub.1 and R.sub.2, which may be the same or different, each is a hydrogen atom or a (C.sub.1 -C.sub.4)alkyl group, or a group of the formula:--S--Hetin which Het is a heterocyclic ring containing 1 to 5 oxygen, nitrogen and sulfur atoms as a hetero atom, in which the heterocyclic ring system may be either polycyclic or 5- or 6-membered monocyclic and may be unsubstituted or substituted; and M is a hydrogen atom or a biologically active carboxyl-protecting group, or is an anionic charge only when X is a pyridinium group; and the pharamaceutically acceptable salts thereof, which are useful as antimicrobial agents and prepared by the reaction of a compound of the formula (II):HO--A--COOH (II)wherein A is as defined above, or a reactive derivative thereof, with a compound of the formula (III): ##STR3## wherein R, M and X are as defined above, or a derivative thereof.
摘要翻译：式（I）的头孢菌素：其中A是含有至少一个氮原子作为杂原子的单环或多环杂芳环，其可以是未取代的或取代的; R是可以是未取代或取代的苯基，噻吩基，呋喃基，环己二烯基或环己烯基; X是乙酰氧基，可以是未取代的或被甲基或氨基甲酰基取代的吡啶鎓基，下式的基团：其中R 1和R 2可以相同或不同，各自为氢原子或（C 1 -C 4）烷基或其中Het为含有1至5个氧，氮和硫原子作为杂原子的杂环的式-S-Het基团，其中杂环系统可以可以是多环或5-或6-元单环，并且可以是未取代的或取代的; M为氢原子或生物活性羧基保护基，或仅当X为吡啶鎓基时为阴离子电荷; 和其药物学上可接受的盐，其可用作抗微生物剂并通过式（II）化合物：其中A如上定义的HO-A-COOH（II）或其反应性衍生物与式（III）的化合物：其中R，M和X如上定义，或其衍生物。

18. 发明授权

US4061748A 7-(.alpha.-(4 -Hydroxy-1,5-naphthyridine-3-carbonamido)-.alpha.-phenylacetamido) cephalosporin derivatives 失效
标题翻译： 7 - （{60-（4-羟基-1,5-二氮杂萘-3-碳酰氨基） - {60-苯乙酰氨基）头孢菌素衍生物
公开(公告)号：US4061748A
公开(公告)日：1977-12-06
申请号：US674205
申请日：1976-04-05
申请人： Hirotada Yamada , Kosaku Okamura , Hisao Tobiki , Norihiko Tanno , Kozo Shimago , Takenari Nakagome , Toshiaki Komatsu , Akio Izawa , Hiroshi Noguchi , Kenji Irie , Yasuko Eda
发明人： Hirotada Yamada , Kosaku Okamura , Hisao Tobiki , Norihiko Tanno , Kozo Shimago , Takenari Nakagome , Toshiaki Komatsu , Akio Izawa , Hiroshi Noguchi , Kenji Irie , Yasuko Eda
IPC分类号： C07D519/06 , A61K31/545 , C07D20060101 , C07D501/04 , C07D501/24 , C07D501/32 , C07D501/36 , C07D501/60 , C07D519/00
CPC分类号： C07D501/24
摘要： A cephalosporin derivative of formula (I): ##STR1## wherein X is an --OCOCH.sub.3 group or an -S-Het group in which Het is a 5- or 6-membered heterocyclic ring containing one to four hetero atoms selected from the group consisting of nitrogen, oxygen and sulfur atoms, which may be substituted with one or more substituents, and the non-toxic pharmaceutically acceptable salts thereof which are useful as an antimicrobial material and which are prepared by the reaction of a compound of formula (II): ##STR2## or a reactive derivative thereof, with a compound of formula (III): ##STR3## wherein X is as defined above, or a derivative thereof.
摘要翻译：式（I）的头孢菌素衍生物：其中X是-OCOCH 3基团或-S-Het基团，其中Het是含有1-4个杂原子的5-或6-元杂环可以被一个或多个取代基取代的选自氮，氧和硫原子的原子及其无毒的药学上可接受的盐，其可用作抗微生物材料，并且其通过化合物式（II）化合物或其衍生物与式（III）化合物反应：其中X如上定义，或其衍生物。

19. 发明申请

US20080009381A1 Differential device for vehicle 有权
标题翻译：车辆差速装置
公开(公告)号：US20080009381A1
公开(公告)日：2008-01-10
申请号：US11825020
申请日：2007-07-03
申请人： Noriyuki Sudou , Toshiaki Komatsu
发明人： Noriyuki Sudou , Toshiaki Komatsu
IPC分类号： F16H48/06
CPC分类号： F16H48/30 , F16H48/08 , F16H48/24 , F16H48/34 , F16H2048/204 , F16H2048/346 , F16H2048/382
摘要： A differential device for a vehicle includes a differential casing 15, pinion shafts 25, 27 connected to through-holes of the differential casing 15, pinion gears 3 supported by the pinion shafts 25, 27, a differential mechanism 9 having side gears 5, 7 meshing with the pinion gears 3, a limited-slip differential 11 for limiting a differential rotation of the differential mechanism 9 and an actuator 13 for controlling the limited-slip differential 11. A ring gear is fixed on a flange part 17 of the differential casing 15. The flange part 17 is positioned on one side of the differential casing 15 in an axial direction of the differential casing disproportionately. The actuator 13 is arranged so as to abut on the flange part 17. The differential casing 15 is divided into casing pieces by a parting part 19 on one side of the differential casing 15 in opposition to the flange part 17 in the axial direction. The casing pieces are connected with each other by connecting members 21.
摘要翻译：用于车辆的差动装置包括差速器壳体15，连接到差速器壳体15的通孔的小齿轮轴25,27，由小齿轮轴25,27支撑的小齿轮3，具有侧齿轮5,7的差动机构9 与小齿轮3啮合，用于限制差速机构9的差速旋转的限滑差速器11和用于控制限滑差速器11的致动器13。齿圈固定在差速器壳体15的凸缘部17上。凸缘部17在差速器壳体的轴向方向上分别位于差速器壳体15的一侧。致动器13布置成邻接在凸缘部17上。差速器壳体15通过在差速器壳体15的与轴向方向相对的凸缘部17的一侧上的分离部分19分成壳体件。壳体通过连接构件21彼此连接。

20. 发明授权

US5023695A Flat cooling structure of integrated circuit 失效
标题翻译：集成电路平面冷却结构
公开(公告)号：US5023695A
公开(公告)日：1991-06-11
申请号：US349411
申请日：1989-05-08
申请人： Kazuhiko Umezawa , Toshiaki Komatsu , Jun Kubokawa
发明人： Kazuhiko Umezawa , Toshiaki Komatsu , Jun Kubokawa
IPC分类号： H01L23/473
CPC分类号： H01L23/4735 , H01L2224/16
摘要： A circuit assembly with circulation of coolant. A plurality of chips of integrated circuit are arranged on a substrate separately from each other in rows and columns. A circulating unit disposed on the substrate and having a planar shape circulates coolant therethrough. The circulating unit has within its bottom side a plurality of cells arranged in rows and columns correspondingly to the plurality of chips. Each individual cell is thermally connected to the corresponding individual chip so as to receive therefrom heat generated thereby. The circulating unit includes a distributor for distributing to the respective cells the circulated coolant effective to absorb the heat received in the respective cells.

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