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11. 发明授权

US08184888B2 Method and system for polyp segmentation for 3D computed tomography colonography 有权
标题翻译：用于3D计算机断层扫描结构的息肉分割方法和系统
公开(公告)号：US08184888B2
公开(公告)日：2012-05-22
申请号：US12231772
申请日：2008-09-05
申请人： Le Lu , Adrian Barbu , Matthias Wolf , Sarang Lakare , Luca Bogoni , Marcos Salganicoff , Dorin Comaniciu
发明人： Le Lu , Adrian Barbu , Matthias Wolf , Sarang Lakare , Luca Bogoni , Marcos Salganicoff , Dorin Comaniciu
IPC分类号： G06K9/46
CPC分类号： G06T7/0012 , G06T7/11 , G06T7/143 , G06T2207/10081 , G06T2207/20076 , G06T2207/30032
摘要： A method and system for polyp segmentation in computed tomography colonogrphy (CTC) volumes is disclosed. The polyp segmentation method utilizes a three-staged probabilistic binary classification approach for automatically segmenting polyp voxels from surrounding tissue in CTC volumes. Based on an input initial polyp position, a polyp tip is detected in a CTC volume using a trained 3D point detector. A local polar coordinate system is then fit to the colon surface in the CTC volume with the origin at the detected polyp tip. Polyp interior voxels and polyp exterior voxels are detected along each axis of the local polar coordinate system using a trained 3D box. A boundary voxel is detected on each axis of the local polar coordinate system based on the detected polyp interior voxels and polyp exterior voxels by boosted 1D curve parsing using a trained classifier. This results in a segmented polyp boundary.
摘要翻译：公开了一种计算机断层扫描（CTC）体积中息肉分割的方法和系统。息肉分割方法采用三阶段概率二分类方法，自动分割CTC体积周围组织的息肉体素。基于输入的初始息肉位置，使用训练有素的3D点检测器在CTC体积中检测息肉末端。然后将局部极坐标系拟合到CTC体积中的结肠表面，其中原点在检测到的息肉末端。使用训练有素的3D框，在局部极坐标系的每个轴上检测Polyp内部体素和息肉外部体素。基于检测到的息肉内部体素和息肉外部体素，通过使用训练有素的分类器进行升压1D曲线解析，在局部极坐标系的每个轴上检测边界体素。这导致分段息肉边界。

12. 发明授权

US08126244B2 User interface for polyp annotation, segmentation, and measurement in 3D computed tomography colonography 有权
标题翻译：用于三维计算机断层扫描结构中息肉注解，分割和测量的用户界面
公开(公告)号：US08126244B2
公开(公告)日：2012-02-28
申请号：US12231771
申请日：2008-09-05
申请人： Le Lu , Adrian Barbu , Matthias Wolf , Sarang Lakare , Luca Bogoni , Marcos Salganicoff , Dorin Comaniciu
发明人： Le Lu , Adrian Barbu , Matthias Wolf , Sarang Lakare , Luca Bogoni , Marcos Salganicoff , Dorin Comaniciu
IPC分类号： G06K9/34
CPC分类号： G16H40/63 , G06F19/00 , G06T7/0012 , G06T7/12 , G06T2200/24 , G06T2207/10072 , G06T2207/20092 , G06T2207/30032
摘要： A method and system for providing a user interface for polyp annotation, segmentation, and measurement in computer tomography colonography (CTC) volumes is disclosed. The interface receives an initial polyp position in a CTC volume, and automatically segments the polyp based on the initial polyp position. In order to segment the polyp, a polyp tip is detected in the CTC volume using a trained 3D point detector. A local polar coordinate system is then fit to the colon surface in the CTC volume with the origin at the detected polyp tip. Polyp interior voxels and polyp exterior voxels are detected along each axis of the local polar coordinate system using a trained 3D box. A boundary voxel is detected on each axis of the local polar coordinate system based on the detected polyp interior voxels and polyp exterior voxels by boosted 1D curve parsing using a trained classifier. This results in a segmented polyp boundary. The segmented polyp is displayed in the user interface, and a user can modify the segmented polyp boundary using the interface. The interface can measure the size of the segmented polyp in three dimensions. The user can also use the interface for polyp annotation in CTC volumes.
摘要翻译：公开了一种用于在计算机断层造影（CTC）体积中提供用于息肉注释，分割和测量的用户界面的方法和系统。界面在CTC体积中接收初始息肉位置，并根据初始息肉位置自动分段息肉。为了分割息肉，使用训练有素的3D点检测器在CTC体积中检测息肉末端。然后将局部极坐标系拟合到CTC体积中的结肠表面，其中原点在检测到的息肉末端。使用训练有素的3D框，在局部极坐标系的每个轴上检测Polyp内部体素和息肉外部体素。基于检测到的息肉内部体素和息肉外部体素，通过使用训练有素的分类器进行升压1D曲线解析，在局部极坐标系的每个轴上检测边界体素。这导致分段息肉边界。分段息肉显示在用户界面中，用户可以使用界面修改分段息肉边界。界面可以在三维中测量分段息肉的大小。用户还可以在CTC卷中使用界面进行息肉注释。

13. 发明授权

US08073217B2 Structure segmentation via MAR-cut 有权
标题翻译：通过MAR切割的结构分割
公开(公告)号：US08073217B2
公开(公告)日：2011-12-06
申请号：US12259322
申请日：2008-10-28
申请人： Hui Sun , Sangmin Park , Sarang Lakare
发明人： Hui Sun , Sangmin Park , Sarang Lakare
IPC分类号： G06K9/00
CPC分类号： G06T7/162 , G06T7/11 , G06T7/149 , G06T2207/10072 , G06T2207/20101 , G06T2207/20124 , G06T2207/30096
摘要： A method for segmenting image data includes creating a plurality of marching regions within the medical image data. Region-wise segmentation is performed on the plurality of marching regions. Region-wise segmentation may include a normalized cut performed on a graph wherein each marching region represents a node. Region-wise segmentation may also include or may alternatively include a min cut performed on a graph wherein each marching region represents a node. Voxel-wise segmentation is performed on a subset of the plurality of marching regions.
摘要翻译：用于分割图像数据的方法包括在医学图像数据内创建多个行进区域。对多个行进区域执行区域划分。区域分割可以包括在图上执行的归一化切割，其中每个行进区域表示节点。区域分割还可以包括或可选地包括在图上执行的最小切割，其中每个行进区域表示节点。在多个行进区域的子集上执行体素分割。

14. 发明授权

US07876947B2 System and method for detecting tagged material using alpha matting 有权
标题翻译：使用阿尔法消光法检测标签材料的系统和方法
公开(公告)号：US07876947B2
公开(公告)日：2011-01-25
申请号：US12244428
申请日：2008-10-02
申请人： Tin Man Lee , Sarang Lakare , Matthias Wolf
发明人： Tin Man Lee , Sarang Lakare , Matthias Wolf
IPC分类号： G06K9/00 , A61B6/00
CPC分类号： G06T7/155 , G06T7/11 , G06T7/143 , G06T2207/10081 , G06T2207/30032 , G06T2207/30096
摘要： A method for computer-aided object classification, soft segmentation and layer extraction in computed tomographic colonography includes providing a contrast enhanced computed tomography (CT) digital image of the colon, finding a foreground region of voxels with an intensity higher than a pre-defined foreground threshold, creating a 3D trimap of the colon where the image is segmented into the foreground region, a background region, and an unknown region between the foreground and background, starting from the background, extracting successive layers of the unknown region until the foreground region is reached, and classifying each extracted layer as background or foreground, and generating a foreground matte, a background matte, and an alpha matte, where alpha indicates a mixing ration of foreground and background voxels.
摘要翻译：计算机辅助对象分类，计算机断层造影中的软分割和层提取的方法包括提供冒号的对比度增强计算机断层摄影（CT）数字图像，找到具有高于预定义前景的体素的前景区域阈值，从背景开始，将图像分割成前景区域，背景区域和前景和背景之间的未知区域，从而提取未知区域的连续层，直到前景区域为达到并将每个提取的层分类为背景或前景，并生成前景无光泽，背景无光泽和阿尔法无光泽，其中alpha表示前景和背景体素的混合比。

15. 发明申请

US20090309874A1 Method for Display of Pre-Rendered Computer Aided Diagnosis Results 审中-公开
标题翻译：显示预渲染计算机辅助诊断结果的方法
公开(公告)号：US20090309874A1
公开(公告)日：2009-12-17
申请号：US12420430
申请日：2009-04-08
申请人： Marcos Salganicoff , Arun Krishnan , Sarang Lakare
发明人： Marcos Salganicoff , Arun Krishnan , Sarang Lakare
IPC分类号： G06T15/00
CPC分类号： G06T19/00 , A61B6/463 , A61B6/466 , A61B6/5217 , A61B6/563 , G06F19/321 , G06T2210/41
摘要： A method for displaying pre-rendered medical images on a workstation includes receiving three-dimensional medical image data. A region of suspicion is automatically identified within the three-dimensional medical image data. A rendering workstation is used to pre-render the three-dimensional medical image data into a sequence of two-dimensional images in which the identified region of suspicion is featured from a vantage point that is automatically selected to maximize diagnostic value of the two-dimensional images for determining whether the region of suspicion is an actual abnormality. The sequence of pre-rendered two-dimensional images is then stored in a PACS, where it can then be displayed on a viewing workstation.
摘要翻译：一种用于在工作站上显示预先呈现的医学图像的方法包括接收三维医学图像数据。在三维医学图像数据内自动识别怀疑区域。渲染工作站用于将三维医学图像数据预渲染成二维图像序列，其中所识别的怀疑区域的特征在于自动选择的有利位置以最大化二维的诊断价值用于确定怀疑区域是否是实际异常的图像。然后将预渲染的二维图像的序列存储在PACS中，然后可以将其显示在观看工作站上。

16. 发明申请

US20060215894A1 System and method for smart display of CAD markers 有权
标题翻译：用于智能显示CAD标记的系统和方法
公开(公告)号：US20060215894A1
公开(公告)日：2006-09-28
申请号：US11385211
申请日：2006-03-21
申请人： Sarang Lakare
发明人： Sarang Lakare
IPC分类号： G06K9/00
CPC分类号： G06F19/321 , G06F19/00
摘要： A method for displaying computer aided detection markers from a digitized image includes marking a first set of locations of interest during a first read of the image, producing a first set of markers, receiving a second set of markers of locations of interest on the image from the CAD algorithm, combining the first set of markers with the second set of markers, sorting the combined set of markers according to a predetermined criteria; and presenting the sorted set of markers to a user for a second read of said image.
摘要翻译：用于从数字化图像显示计算机辅助检测标记的方法包括在图像的第一次读取期间标记感兴趣的第一组位置，产生第一组标记，在图像上接收感兴趣位置的第二组标记， CAD算法，将第一组标记与第二组标记组合，根据预定标准对组合标记进行排序; 以及将用于所述图像的第二次读取的所述排序的标记集合呈现给用户。

17. 发明授权

US08265390B2 Probabilistic segmentation in computer-aided detection 有权
标题翻译：计算机辅助检测中的概率分割
公开(公告)号：US08265390B2
公开(公告)日：2012-09-11
申请号：US12555799
申请日：2009-09-08
申请人： Shishir Dube , Sarang Lakare , Gerardo Hermosillo Valadez , Yoshihisa Shinagawa
发明人： Shishir Dube , Sarang Lakare , Gerardo Hermosillo Valadez , Yoshihisa Shinagawa
IPC分类号： G06K9/00
CPC分类号： G06K9/342 , G06T5/002 , G06T5/40 , G06T7/11 , G06T7/187 , G06T2207/30068
摘要： Described herein is a method and system for facilitating segmentation of images. A difference image is received and processed to extract at least one histogram (402). A noise component is determined by fitting a symmetric Gaussian distribution to the extracted histogram such that the negative portion of the Gaussian distribution coincides with the negative portion of the histogram (403). The noise component is then subtracted from the histogram to generate a probability distribution function (404), which may be converted to a cumulative distribution function (406) and applied to the difference image to generate a probabilistic representation of contrast enhancement (408).
摘要翻译：这里描述了一种便于图像分割的方法和系统。差分图像被接收和处理以提取至少一个直方图（402）。通过将对称高斯分布拟合到所提取的直方图来确定噪声分量，使得高斯分布的负部分与直方图（403）的负部分重合。然后从直方图中减去噪声分量以产生概率分布函数（404），该概率分布函数可被转换为累积分布函数（406）并应用于差分图像以生成对比度增强的概率表示（408）。

18. 发明授权

US07609876B2 Virtual grid alignment of sub-volumes 有权
标题翻译：子卷的虚拟网格对齐
公开(公告)号：US07609876B2
公开(公告)日：2009-10-27
申请号：US11255263
申请日：2005-10-21
申请人： Sarang Lakare , Luca Bogoni
发明人： Sarang Lakare , Luca Bogoni
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , G06T19/20 , G06T2219/2004
摘要： A computer-implemented method for aligning sub-volumes includes receiving a data volume, providing a plurality of parameters of the sub-volumes, and determining a start point of each of the two or more sub-volume according to the plurality of parameters. The method further includes determining an amount of mis-alignment of the two or more sub-volumes, and shifting a start point of each sub-volume to align the start points with a grid of a virtual volume. The method may include determining a feature in the two or more sub-volumes, which have been aligned. The method may include visualizing the aligned sub-volumes.
摘要翻译：用于对准子卷的计算机实现的方法包括接收数据卷，提供子卷的多个参数，以及根据多个参数确定两个或更多子卷中的每一个的起始点。该方法还包括确定两个或多个子体积的错配量，以及移动每个子体积的起始点以使开始点与虚拟体积的网格对准。该方法可以包括确定已对齐的两个或多个子卷中的特征。该方法可以包括可视化对准的子体积。

19. 发明授权

US07492968B2 System and method for segmenting a structure of interest using an interpolation of a separating surface in an area of attachment to a structure having similar properties 有权
标题翻译：用于使用在与具有相似性质的结构连接的区域中的分离表面的插值来分割感兴趣结构的系统和方法
公开(公告)号：US07492968B2
公开(公告)日：2009-02-17
申请号：US11207318
申请日：2005-08-19
申请人： Anna Jerebko , Luca Bogoni , Sarang Lakare
发明人： Anna Jerebko , Luca Bogoni , Sarang Lakare
IPC分类号： G06K9/32
CPC分类号： G06T7/12 , G06T7/181 , G06T2207/10072 , G06T2207/30032 , G06T2207/30064
摘要： A system and method for segmenting a structure of interest are provided. The method comprises: segmenting a surface of the structure of interest; and interpolating a border of the structure of interest, wherein the border separates the structure of interest from other structures having similar properties.
摘要翻译：提供了一种用于分割感兴趣的结构的系统和方法。该方法包括：分割感兴趣结构的表面; 并且内插所关注的结构的边界，其中边界将感兴趣的结构与具有相似属性的其他结构分开。

20. 发明申请

US20080211826A1 Circular Intensity Distribution Analysis for the Detection of Convex, Concave and Flat Surfaces 有权
标题翻译：凸面，凹面和平面检测的圆形强度分布分析
公开(公告)号：US20080211826A1
公开(公告)日：2008-09-04
申请号：US12018496
申请日：2008-01-23
申请人： Sarang Lakare
发明人： Sarang Lakare
IPC分类号： G09G5/00
CPC分类号： G06K9/48 , G06K9/50
摘要： A method for characterizing a shape of an object surface includes acquiring image data including the object. The image data is analyzed at a locus of points that are at a predetermined distance from a point of interest proximate to the object surface to determine which of the locus of points represents a foreground and which of the locus of points represents a background. The shape of the object surface is characterized based on the characterization of the locus of points.
摘要翻译：用于表征物体表面的形状的方法包括获取包括物体的图像数据。在距离物体表面附近的感兴趣点的预定距离的点处分析图像数据，以确定点的轨迹中哪一个表示前景，并且点的轨迹中的哪一个表示背景。物体表面的形状基于点的轨迹的表征来表征。

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