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11. 发明授权

US07014810B2 Method of producing solid shape forms containing an active ingredient 有权
标题翻译：制备含有活性成分的固体形状的方法
公开(公告)号：US07014810B2
公开(公告)日：2006-03-21
申请号：US10149762
申请日：2000-12-15
申请人： Harald Krull , Jörg Rosenberg , Jörg Breitenbach , Jürgen Hofmann , Rainer Klenz , Hans Bührle
发明人： Harald Krull , Jörg Rosenberg , Jörg Breitenbach , Jürgen Hofmann , Rainer Klenz , Hans Bührle
IPC分类号： B29C45/03 , B29C45/72
CPC分类号： B29C45/54 , A61J3/06 , A61K9/2095 , B29C45/542 , B29C2045/466 , B29C2045/545 , B29K2105/0035
摘要： The present invention relates to an apparatus for producing solid active ingredient-containing forms from an active ingredient-containing formulation which comprises at least one polymeric binder. The apparatus according to the invention has at least one extruder 1 for continuous plastication of the formulation and at least two injection units 2 which are provided separate from one another, each of which is connected to the extruder 1, and through which the formulation can be injected into at least one mold 3. In the process according to the invention for producing solid active ingredient-containing forms from an active ingredient-containing formulation which comprises at least one binder, the active ingredient-containing formulation is continuously plasticated, the plasticated formulation is fed into an injection unit 21, and the formulation present in this injection unit 21 is injected into a mold 3, and plasticated formulation is fed into another injection molding unit 22, and the formulation present in the other injection molding unit 22 is injected into the mold 3 or another mold.
摘要翻译：本发明涉及包含至少一种聚合物粘合剂的含活性成分的制剂的含固体活性成分的形式的装置。根据本发明的装置具有至少一个用于制剂的连续塑化的挤出机1和至少两个彼此分离的注射单元2，每个注射单元2彼此连接到挤出机1，并且制剂可以通过该挤出机1 注入至少一个模具3。在根据本发明的用于由含有至少一种粘合剂的含活性成分的制剂生产含固体活性成分的制剂的方法中，含有活性成分的制剂被连续塑化，所述塑化的制剂进料到注射单元2' SUB＆gt; 1，并且将存在于该注射单元2 1中的制剂注射到模具3中，并且将塑化的制剂进料到另一个注射成型单元2 2 / >，并且存在于另一个注射成型单元2 2中的配方被注入到模具3或另一个模具中。

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