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11. 发明申请

WO1993010252A1 PROCESS FOR PRODUCING L-ALANINE BY FERMENTATION 审中-公开
标题翻译：通过发酵生产L-ALANINE的方法
公开(公告)号：WO1993010252A1
公开(公告)日：1993-05-27
申请号：PCT/JP1991001574
申请日：1991-11-18
申请人： KYOWA HAKKO KOGYO CO., LTD. , KATSUMATA, Ryoichi , HASHIMOTO, Shinichi , KAWAMOTO, Isao , SUZUKI, Makoto , YOSHIDA, Hajime , HAGINO, Hiroshi , NAKAYAMA, Kiyoshi
发明人： KYOWA HAKKO KOGYO CO., LTD.
IPC分类号： C12P13/06
CPC分类号： C12R1/06 , C12P13/06
摘要： A process for producing L-alanine which comprises culturing a micro-organism which belongs to the genus Arthrobacter, has an L-alaline dehydrogenase activity and scarcely any or no alanine racemase activity, and is capable of producing L-alanine in a medium, accumulating the produced L-alanine in the media, and separating L-alanine thereform.
摘要翻译：一种生产L-丙氨酸的方法，其包括培养属于节杆菌属的微生物，具有L-丙氨酸脱氢酶活性，几乎不具有任何或不具有丙氨酸消旋酶活性，并且能够在培养基中产生L-丙氨酸，培养基中产生的L-丙氨酸，并分离出L-丙氨酸。

12. 发明申请

WO1997002293A1 POLYCARBOXYLIC ACID DERIVED FROM POLYSACCHARIDE COMPOSED OF ANHYDROUS GLUCOSE UNITS, SALTS THEREOF, AND PROCESS FOR THE PREPARATION THEREOF 审中-公开
标题翻译：由多糖制成的聚碳酸酯，由其制成的无糖葡萄糖单体及其制备方法及其制备方法
公开(公告)号：WO1997002293A1
公开(公告)日：1997-01-23
申请号：PCT/JP1996001809
申请日：1996-06-28
申请人： LION CORPORATION , DANNOUE, Yukihiro , MOROHARA, Kiyoshi , NAKAYAMA, Kiyoshi
发明人： LION CORPORATION
IPC分类号： C08B37/00
CPC分类号： C11D3/223 , C08B15/02 , C08B31/18
摘要： A polycarboxylic acid prepared by the oxidation of a polysaccharide composed of anhydrous glucose units and having a high carboxyl content and a weight-average molecular weight of 2000 or above; or salts thereof. This acid consumes 435 mg or above of alkali in terms of sodium hydroxide for neutralization of 1g of the same and exhibits a high chelating activity against polyvalent cations, thus being suitable for detergent builders. The acid can be prepared by oxidizing a polysaccharide with an oxidizing agent in the presence of a transition metal catalyst.
摘要翻译：通过氧化由无水葡萄糖单元组成的多糖并且具有高羧基含量和2000以上的重均分子量制备的多元羧酸; 或其盐。该酸以氢氧化钠的方式消耗435mg以上的碱以中和1g相同的物质，并且对多价阳离子具有高螯合活性，因此适用于洗涤剂助洗剂。酸可以通过在过渡金属催化剂存在下用氧化剂氧化多糖来制备。

13. 发明申请

WO1995026978A1 CYCLIC PEPTIDE AND PROCESS FOR PRODUCING THE SAME 审中-公开
标题翻译：循环肽及其生产方法
公开(公告)号：WO1995026978A1
公开(公告)日：1995-10-12
申请号：PCT/JP1995000611
申请日：1995-03-30
申请人： MERCIAN CORPORATION , DAIICHI PHARMACEUTICAL CO., LTD. , AGEMATSU, Hitoshi , CHIBA, Hiroyuki , KANETO, Rei , OHTA, Toshiharu , NAKAYAMA, Kiyoshi
发明人： MERCIAN CORPORATION , DAIICHI PHARMACEUTICAL CO., LTD.
IPC分类号： C07K05/08
CPC分类号： C07K5/0202 , A61K38/00 , C07K5/0806
摘要： A cyclic tetrapeptide or a corresponding depsipeptide represented by general formula (I) and a salt thereof, wherein R , R and R represent each independently, together with the alpha -amino acid units to which they are bonded, an appropriate alpha -amino acid residue; Q represents NR or oxygen; and Q represents an optionally substituted bonding group. These peptides have an antifungal activity and are useful for treating infectious diseases.
摘要翻译：由通式（I）表示的环状四肽或相应的缩酚酸肽及其盐，其中R 5，R 6和R 7各自独立地表示与它们所属的α-氨基酸单元键合，合适的α-氨基酸残基; Q 1表示NR 4或氧; 并且Q 2表示任选取代的键合基团。这些肽具有抗真菌活性，可用于治疗感染性疾病。

14. 发明申请

WO1995023889A1 FIBER TREATMENT, COSMETIC, POLYMERIC COMPOUND HAVING ORGANOPOLYSILOXANE SIDE CHAINS, AND PROCESS FOR PRODUCING SILICONE COPOLYMER 审中-公开
标题翻译：纤维处理，化妆品，具有有机硅氧烷侧链的聚合物，以及生产硅酮共聚物的方法
公开(公告)号：WO1995023889A1
公开(公告)日：1995-09-08
申请号：PCT/JP1995000353
申请日：1995-03-03
申请人： LION CORPORATION , SHIMIZU, Yoshio , TAKIZAWA, Masahiro , ISODA, Masanori , SHIBAZAKI, Kenichiro , NAKAYAMA, Kiyoshi
发明人： LION CORPORATION
IPC分类号： D06M15/263
CPC分类号： D06M15/643 , A61K8/64 , A61K8/73 , A61K8/898 , A61Q5/00 , C07K1/1077 , C08B37/00 , C08F30/08 , C08H1/00 , D06M15/03 , D06M15/15 , D06M15/263 , D06M15/3568
摘要： A fiber treatment comprising a polymeric compound having organopolysiloxane side chains, and a cosmetic containing the above compound as a film-forming agent. Polysaccharide and protein compounds each having organopolysiloxane side chains, and a silicone copolymer having organopolysiloxane side chains and a process for producing the copolymer.
摘要翻译：包括具有有机聚硅氧烷侧链的聚合物的纤维处理剂和含有上述化合物作为成膜剂的化妆品。各自具有有机聚硅氧烷侧链的多糖和蛋白质化合物和具有有机聚硅氧烷侧链的硅氧烷共聚物和共聚物的制造方法。

15. 发明申请

WO1992012251A1 PROCESS FOR PRODUCING (R)-MALIC ACID, MICROBIAL MALEATE HYDRATASE, AND PROCESS FOR PRODUCING SAID HYDRATASE 审中-公开
标题翻译：用于制备（R） - 酸，微生物MALEATE HYDRATASE的方法，以及用于生产SAID HYDRATASE的方法
公开(公告)号：WO1992012251A1
公开(公告)日：1992-07-23
申请号：PCT/JP1991000025
申请日：1991-01-14
申请人： BIOR INC. , NAKAYAMA, Kiyoshi , KOBAYASHI, Yukie
发明人： BIOR INC.
IPC分类号： C12P07/46
CPC分类号： C12P7/46 , C12N9/88 , Y10S435/822 , Y10S435/911
摘要： A process for producing (R)-malic acid with a high optical purity efficiently and economically, which comprises bringing maleic acid into contact with a microbial maleate hydratase which produces (R)-malic acid by the hydration of maleic acid or a microorganism containing the hydratase.

16. 发明申请

WO2008082009A3 FUSED SUBSTITUTED AMINOPYRROLIDINE DERIVATIVE 审中-公开
公开(公告)号：WO2008082009A3
公开(公告)日：2008-07-10
申请号：PCT/JP2007/075434
申请日：2007-12-28
申请人： DAIICHI SANKYO COMPANY, LIMITED , TAKAHASHI, Hisashi , KOMORIYA, Satoshi , KITAMURA, Takahiro , ODAGIRI, Takashi , INAGAKI, Hiroaki , TSUDA, Toshifumi , NAKAYAMA, Kiyoshi , TAKEMURA, Makoto , YOSHIDA, Kenichi , MIYAUCHI, Rie , NAGAMOCHI, Masatoshi
发明人： TAKAHASHI, Hisashi , KOMORIYA, Satoshi , KITAMURA, Takahiro , ODAGIRI, Takashi , INAGAKI, Hiroaki , TSUDA, Toshifumi , NAKAYAMA, Kiyoshi , TAKEMURA, Makoto , YOSHIDA, Kenichi , MIYAUCHI, Rie , NAGAMOCHI, Masatoshi
IPC分类号： C07D401/04 , C07D401/14 , C07D491/052 , C07D498/04 , A61K31/47 , A61P31/04
摘要： A quinolone synthetic antibacterial agent having excellent properties as a medicine is provided, which has strong antibacterial activity not only to Gram-negative bacteria but also to Gram-positive cocci that have low sensitivity to quinolone antibacterial agents, and which exhibits high safety and excellent pharmacokinetics. A compound represented by the formula (I) or a salt thereof, or a hydrate thereof. Specifically, a quinolone derivative of the formula (I) wherein substituents R6 and R7 taken together with the carbon atoms to which they are bonded form a cyclic structure which may contain an oxygen atom as a ring constituent atom, the cyclic structure forming a 5-4, 5-5, or 5-6 fused bicyclic pyrrolidinyl substituent, the substituent being bonded to a quinolone mother skeleton Q containing a pyridobenzoxazine structure.

17. 发明专利

JPH03286750A ULTRASONIC DIAGNOSTIC DEVICE 失效
公开(公告)号：JPH03286750A
公开(公告)日：1991-12-17
申请号：JP8855290
申请日：1990-04-03
申请人： NAKAYAMA KIYOSHI , FUJITSU LTD
发明人： NAKAYAMA KIYOSHI
IPC分类号： G01N29/06 , A61B8/00 , G01N29/04 , G01N29/22 , G01N29/44
摘要： PURPOSE:To highly maintain the frame rate, to obtain uniform beam width in the distance direction, and also, to obtain a high picture quality in any patient by providing a means for estimating a transfer characteristics of a two-dimensional point expansion function of the ultrasonic scanning face from plural ultrasonic receiving waves, and convoluting an impulse response of a two-dimensional shaping filter to plural receiving waves. CONSTITUTION:A transfer characteristic of a target function is divided by a transfer characteristic of a two-dimensional point expansion function by a divider 2-1, and an impulse response of a two-dimensional shaping filter is calculated by a high speed two-dimensional reverse Fourier-converter 2-2, and recorded temporarily in a memory 2-3. Subsequently, while reading out a series of values in the distance direction of the impulse response of the two-dimensional shaping filter from the memory 2-3, and while setting it to a coefficient of a one-dimensional time-varying filter 3-1, an ultrasonic receiving wave read out in the distance direction from a frame memory is allowed to pass through the one-dimensional time-varying filter 3-1 and recorded in a frame memory 3-2.

18. 发明专利

JPS62109553A ULTRASONIC APPARATUS FOR MEASURING CHARACTERISTICS OF LIVINGBODY 失效
公开(公告)号：JPS62109553A
公开(公告)日：1987-05-20
申请号：JP25054485
申请日：1985-11-08
申请人： FUJITSU LTD , NAKAYAMA KIYOSHI
发明人： NAKAYAMA KIYOSHI , SHINAMI AKIRA , MIWA HIROHIDE , MURAKAMI KEIICHI , YAMADA ISAMU , HAYASHI OSAMU , SHIMURA NOBUSHIRO
IPC分类号： A61B8/08 , G01N29/06

19. 发明专利

JPS5526362A LATTICEETYPE UNIVERSAL FENCE 失效
公开(公告)号：JPS5526362A
公开(公告)日：1980-02-25
申请号：JP9860678
申请日：1978-08-11
申请人： NAKAYAMA KIYOSHI
发明人： NAKAYAMA KIYOSHI
IPC分类号： E04H17/14 , B21F27/10 , B21F29/00

20. 发明专利

JPS5448939A METHOD OF MOUNTING LOWER DRUM EDGE OF FENCE 失效
公开(公告)号：JPS5448939A
公开(公告)日：1979-04-17
申请号：JP11489277
申请日：1977-09-24
申请人： NAKAYAMA KIYOSHI
发明人： NAKAYAMA KIYOSHI
IPC分类号： E04H17/04 , E04H17/06

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