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11. 发明申请

WO2006058328A3 ROTATING FINE NEEDLE FOR CORE TISSUE SAMPLING 审中-公开
公开(公告)号：WO2006058328A3
公开(公告)日：2006-06-01
申请号：PCT/US2005/043098
申请日：2005-11-29
申请人： GRANIT MEDICAL INNOVATIONS, LLC , NAKAO, Naomi, L.
发明人： NAKAO, Naomi, L.
IPC分类号： A61B10/00 , A61B17/32
摘要： A medical instrument usable with an ultrasound-endoscope for performing a needle biopsy on a patient's internal body tissues usable at a surgical site not visible to the unaided eye or viewed endoscopically, comprises an elongate tubular member with a hollow needle element connected at its distal end, a sheath member housing said tubular member and needle element, an actuator subassembly with a shifter member operatively connected to elongate tubular member's proximal end, and a distal camming subassembly, said subassembly enabling a rotating motion of said needle member while handle actuator is moved in the forward direction. Upon inserting an ultrasound-endoscope into a patient and locating a mass, the fine needle with sharply pointed spoon shaped distal end is inserted into the mass aided by endoscopic and ultrasonographic guidance. Once in the mass, a camming action is initiated, causing rotation of the fine needle within the mass, resulting in a scooped out core biopsy. This instrument enables the performance of a fine needle aspiration requiring only one or two needle introductions, with a resultant core biopsy substantial enough for diagnostic purposes.

12. 发明申请

WO2005096958A3 ENDOSCOPIC FASTENING SYSTEM WITH MULTIPLE FASTENERS 审中-公开
标题翻译：具有多个紧固件的内窥镜紧固系统
公开(公告)号：WO2005096958A3
公开(公告)日：2006-02-16
申请号：PCT/US2005010115
申请日：2005-03-28
申请人： GRANIT MEDICAL INNOVATIONS LLC , NAKAO NAOMI
发明人： NAKAO NAOMI
IPC分类号： A61B17/064 , A61B17/068 , A61B17/08 , A61B17/10 , A61B17/122 , A61B17/128
CPC分类号： A61B17/122 , A61B17/0644 , A61B17/068 , A61B17/0682 , A61B17/083 , A61B17/10 , A61B17/1285
摘要： An endoscopic fastening system having a diameter sufficiently small so that the fastening system is slidably insertable into a working channel of a flexible or rigid endoscope for performing a stapling, clipping, or other fastening operation, comprises one or more surgical fasteners, and a fastener delivery and deployment assembly. One or more fasteners being disposed in a substantially closed prefiring configuration inside the fastener delivery and deployment system are configured for being delivered and deployed into a target tissue while remaining in a substantially closed configuration throughout the entire operation. Other related embodiments of fasteners and their respective delivery and deployment assemblies enabling fastening operations in conjunction with a flexible or rigid endoscope are described.
摘要翻译：一种具有足够小的直径的内窥镜紧固系统，使得紧固系统可滑动地插入柔性或刚性内窥镜的工作通道中，以执行缝合，夹紧或其它紧固操作，包括一个或多个外科紧固件和紧固件递送和部署组件。配置在紧固件传送和展开系统内部的基本封闭的预配置结构中的一个或多个紧固件构造成在整个操作过程中保持基本上封闭的结构，被传送和展开到目标组织中。描述了紧固件及其相应的递送和展开组件的其他相关实施例，其使得能够结合柔性或刚性内窥镜进行紧固操作。

13. 发明申请

WO2005096958A2 ENDOSCOPIC FASTENING SYSTEM WITH MULTIPLE FASTENERS 审中-公开
标题翻译：具有多个紧固件的内窥镜紧固系统
公开(公告)号：WO2005096958A2
公开(公告)日：2005-10-20
申请号：PCT/US2005/010115
申请日：2005-03-28
申请人： GRANIT MEDICAL INNOVATIONS, LLC , NAKAO, Naomi
发明人： NAKAO, Naomi
IPC分类号： A61B17/10
CPC分类号： A61B17/122 , A61B17/0644 , A61B17/068 , A61B17/0682 , A61B17/083 , A61B17/10 , A61B17/1285
摘要： An endoscopic fastening system having a diameter sufficiently small so that the fastening system is slidably insertable into a working channel of a flexible or rigid endoscope for performing a stapling, clipping, or other fastening operation, comprises one or more surgical fasteners, and a fastener delivery and deployment assembly. One or more fasteners being disposed in a substantially closed prefiring configuration inside the fastener delivery and deployment system are configured for being delivered and deployed into a target tissue while remaining in a substantially closed configuration throughout the entire operation. Other related embodiments of fasteners and their respective delivery and deployment assemblies enabling fastening operations in conjunction with a flexible or rigid endoscope are described.
摘要翻译：一种具有足够小的直径的内窥镜紧固系统，使得紧固系统可滑动地插入柔性或刚性内窥镜的工作通道中，以执行缝合，夹紧或其它紧固操作，包括一个或多个外科紧固件和紧固件递送和部署组件。配置在紧固件传送和展开系统内部的基本封闭的预配置结构中的一个或多个紧固件构造成在整个操作过程中保持基本上封闭的结构，被传送和展开到目标组织中。描述了紧固件及其相应的递送和展开组件的其他相关实施例，其使得能够结合柔性或刚性内窥镜进行紧固操作。

14. 发明申请

WO02054942A3 MEDICAL CAUTERIZATION SNARE ASSEMBLY AND ASSOCIATED METHODOLOGY 审中-公开
标题翻译：医疗电脑套圈组装及相关方法
公开(公告)号：WO02054942A3
公开(公告)日：2002-10-03
申请号：PCT/US0200840
申请日：2002-01-11
申请人： WILK & NAKAO MEDICAL TECHNOLOG , WILK PETER J , NAKAO NAOMI
发明人： WILK PETER J , NAKAO NAOMI
IPC分类号： A61B17/00 , A61B17/22 , A61B17/32 , A61B18/14 , A61B19/00 , A61B18/18
CPC分类号： A61B17/32056 , A61B10/02 , A61B17/221 , A61B18/14 , A61B18/1492 , A61B90/37 , A61B2017/00269 , A61B2017/00287 , A61B2018/1407 , A61B2018/141 , A61B2018/1475
摘要： A medical cauterization snare assembly with a tubular member, an electrically conductive cauterization loop ejectable from a distal end of the tubular member, and a capture pouch also ejectable from the distal end of the tubular member. The pouch is attached to an auxiliary loop which has a size larger than that of the cauterization loop. Alternatively, the tubular member is formed at its distal end with a first port or opening and in a distal end portion with a second port or opening spaced from the first port or opening. The two ports or openings both face in a distal direction (i.e., away from the user). The cauterization loop is alternatively ejectable from and retractable into the first port or opening, while the capture pouch is separately ejectable from the second port or opening. Alternatively, the capture pouch is attached to the cauterization loop, to only a proximal portion of the loop to divide the loop's area into a proximal section covered by the pouch and an open or uncovered distal section.
摘要翻译：一种具有管状构件的医疗灼烧圈套组件，可从管状构件的远端弹出的导电烧灼环，以及也可从管状构件的远端弹出的捕获袋。小袋附着在尺寸大于烧灼圈的辅助环上。或者，管状构件在其远端形成有第一端口或开口，并且在远端部分中具有与第一端口或开口隔开的第二端口或开口。两个端口或开口均面向远侧方向（即远离使用者）。烧灼环可替换地从第一端口或开口推出并且可缩回到第一端口或开口中，而捕获袋可单独地从第二端口或开口推出。或者，捕获袋附接至烧灼环，仅附接至环的近端部分，以将环的区域分成由袋覆盖的近端部分和开放或未覆盖的远端部分。

15. 发明申请

WO1993015780A1 ANTICLOTTING DEVICE AND METHOD FOR IV CATHETERS 审中-公开
标题翻译：防静电装置和四导管的方法
公开(公告)号：WO1993015780A1
公开(公告)日：1993-08-19
申请号：PCT/US1993001613
申请日：1993-02-17
申请人： NAKAO, Naomi, L.
发明人： WILK, Peter, J.
IPC分类号： A61M05/00
CPC分类号： A61M25/00 , A61M5/16831 , A61M2005/1404 , Y10S128/12
摘要： A method for use in an intravenous tube assembly (48) comprises the steps of automatically monitoring liquid flow along a fluid flow path (38) extending through an intravenous catheter (34) to detect at least a partial cessation of flow along the fluid flow path (38) and, upon detecting a diminution of liquid flow along the fluid flow path (38), automatically feeding an anticlotting agent to the fluid flow path (38). An assembly for implementing the method takes the form of a pressure sensing device (36) operatively connected to the catheter (34) for automatically detecting at least a partial cessation of liquid flow along a fluid flow path (38) extending through the catheter (34). The assembly also includes a feeder mechanism (26) operatively connected to the catheter (34) and the sensing device (36) for automatically feeding an anticlotting agent (44a) to the fluid flow path (38) through the catheter (34) upon a detection by the sensing device (36) of a diminution of liquid flow along the fluid flow path (38) and, more particularly, of intravenous liquid flow in a distal direction into a patient's circulatory system.

16. 发明申请

WO1993011698A1 ENDOSCOPE SHEATH AND RELATED METHOD 审中-公开
标题翻译：内窥镜和相关方法
公开(公告)号：WO1993011698A1
公开(公告)日：1993-06-24
申请号：PCT/US1992010576
申请日：1992-12-09
申请人： NAKAO, Naomi, L. , WILK, Peter, J.
IPC分类号： A61B01/00
CPC分类号： A61B1/00135 , A61B1/00142 , A61B1/018 , Y10S24/50
摘要： A device utilizable with an endoscope to promote sterility comprises a substantially thin-walled elongate tubular sheath (22) made of a flexible material such as rubber, the sheath (22) having a use configuration with an inner diameter larger than an outer diameter of an insertion member of the endoscope, whereby the sheath (22) may be removably disposed about such insertion member to substantially surround same prior to insertion of the insertion member into a patient. The device further comprises a transparent cap member (24) and an element (26) or elements for attaching the cap member (24) in a fluid tight seal to a distal end of the sheath so that the cap member (24) covers a distal end of the insertion member of the endoscope. Biopsy channels (48) some of which are expandable from collapsed configurations to receive endoscopic surgical instruments during an operation, are provided on or in the sheath (22).

17. 发明申请

WO2006036326A3 ENDOSCOPIC MUCOSAL RESECTION METHOD AND ASSOCIATED INSTRUMENT 审中-公开
标题翻译：内窥镜检查方法及相关仪器
公开(公告)号：WO2006036326A3
公开(公告)日：2007-09-07
申请号：PCT/US2005028743
申请日：2005-08-12
申请人： GRANIT MED INNOVATION LLC , NAKAO NAOMI
发明人： NAKAO NAOMI
IPC分类号： A61B18/18
CPC分类号： A61B10/06 , A61B17/320016 , A61B17/32056 , A61B18/1492 , A61B2017/00269 , A61B2018/00482 , A61B2018/144
摘要： An endoscopic tissue resection device and related method is used in conjunction with a flexible or rigid endoscope. Tissue is resected by shaving thin layers of tissue for diagnostic and therapeutic purposes.
摘要翻译：内窥镜组织切除装置及其相关方法与柔性或刚性内窥镜结合使用。通过剃刮薄层组织切除组织用于诊断和治疗目的。

18. 发明申请

WO2007021565A3 ENDOSCOPIC INSTRUMENT ASSEMBLY WITH SEPARABLE OPERATIVE TIP AND ASSOCIATED MEDICAL METHOD 审中-公开
标题翻译：具有可分离操作尖端的内窥镜器械组件及相关医学方法
公开(公告)号：WO2007021565A3
公开(公告)日：2007-05-03
申请号：PCT/US2006030275
申请日：2006-08-04
申请人： GRANIT MEDICAL INNOVATIONS LLC , NAKAO NAOMI L
发明人： NAKAO NAOMI L
IPC分类号： A61B17/26
CPC分类号： A61B17/0469 , A61B17/062 , A61B17/0625 , A61B17/32056 , A61B18/02 , A61B18/1492 , A61B2017/00269 , A61B2017/00296 , A61B2017/00473 , A61B2017/00827 , A61B2018/1407 , A61B2018/144
摘要： In an insertion configuration, an endoscope assembly includes an insertion member with a distal end face and a working channel and further includes an instrument shaft extending through the working channel and an operative tip connected to the instrument shaft and extending in a plane oriented perpendicularly to the instrument shaft. The operative tip is positioned along the distal end face of the endoscope insertion member. The operative tip is separable from the distal end face of the endoscope insertion member by a distally directed motion of the instrument shaft along the working channel.
摘要翻译：在插入配置中，内窥镜组件包括具有远端面和工作通道的插入构件，并且还包括穿过工作通道延伸的器械杆和连接到器械杆并且在垂直于仪器轴。操作尖端沿着内窥镜插入构件的远端面定位。通过器械轴沿工作通道的远端定向运动，操作尖端可与内窥镜插入构件的远端面分离。

19. 发明申请

WO2007021565A2 ENDOSCOPIC INSTRUMENT ASSEMBLY WITH SEPARABLE OPERATIVE TIP AND ASSOCIATED MEDICAL METHOD 审中-公开
标题翻译：具有可分离操作提示和相关医疗方法的内窥镜检查装置
公开(公告)号：WO2007021565A2
公开(公告)日：2007-02-22
申请号：PCT/US2006/030275
申请日：2006-08-04
申请人： GRANIT MEDICAL INNOVATIONS, LLC , NAKAO, Naomi, L.
发明人： NAKAO, Naomi, L.
IPC分类号： A61B17/26
CPC分类号： A61B17/0469 , A61B17/062 , A61B17/0625 , A61B17/32056 , A61B18/02 , A61B18/1492 , A61B2017/00269 , A61B2017/00296 , A61B2017/00473 , A61B2017/00827 , A61B2018/1407 , A61B2018/144
摘要： In an insertion configuration, an endoscope assembly includes an insertion member with a distal end face and a working channel and further includes an instrument shaft extending through the working channel and an operative tip connected to the instrument shaft and extending in a plane oriented perpendicularly to the instrument shaft. The operative tip is positioned along the distal end face of the endoscope insertion member. The operative tip is separable from the distal end face of the endoscope insertion member by a distally directed motion of the instrument shaft along the working channel.
摘要翻译：在插入构造中，内窥镜组件包括具有远端面和工作通道的插入构件，还包括延伸穿过工作通道的器械轴和连接到仪器轴的操作尖端，并且在垂直于仪表轴。操作尖端沿着内窥镜插入构件的远端面定位。操作尖端通过仪器轴沿着工作通道的远侧定向运动而与内窥镜插入构件的远端面分离。

20. 发明申请

WO2007011837A2 ENDOSCOPE CUTTING AND RETRIEVING SNARE INSTRUMENT 审中-公开
标题翻译：内窥镜切割和检索仪器
公开(公告)号：WO2007011837A2
公开(公告)日：2007-01-25
申请号：PCT/US2006/027603
申请日：2006-07-14
申请人： GRANIT MEDICAL INNOVATIONS, LLC , NAKAO, Naomi, L.
发明人： NAKAO, Naomi, L.
IPC分类号： A61B17/26
CPC分类号： A61B17/32056 , A61B17/221 , A61B2017/00287 , A61B2017/2212
摘要： An endoscopic cutting and retrieval instrument includes an elongate electrically conductive wire and an inner loop and an outer loop both connected to a distal end of the wire. The inner loop and the outer loop have a common proximal loop portion and different distal loop portions. The distal loop portion of the outer loop is longer than the distal loop portion of the inner loop so that the outer loop is larger than the inner loop. A net attached to the outer loop forms a retrieval basket for capturing severed polyps and other tissues masses.
摘要翻译：内窥镜切割和取回仪器包括细长的导电线，以及连接到线的远端的内环和外环。内环和外环具有共同的近端环部分和不同的远端环部分。外环的远端环部比内环的远端环部长，使得外环比内环大。连接到外环的网形成用于捕获切断的息肉和其他组织块的检索篮。

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