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    • 12. 发明申请
    • Pneumatic Bioreactor
    • 气动生物反应器
    • US20080268530A1
    • 2008-10-30
    • US11739659
    • 2007-04-24
    • J. Gregory ZeikusKyungnam KimThomas A. PostKeith E. Johnson
    • J. Gregory ZeikusKyungnam KimThomas A. PostKeith E. Johnson
    • C12M1/02
    • C12M27/06B01F3/04588B01F7/00308B01F7/00916B01F7/04B01F15/005B01F15/00545C12M27/20
    • A pneumatic bioreactor having a containment vessel which includes a semi-cylindrical concavity defined by the vessel bottom. A mixing apparatus includes a rotational mixer rotatably mounted within the containment vessel about a horizontal axis. The rotational mixer has buoyancy-driven mixing cavities which are fed by a gas supply beneath the rotational mixer. The mixing apparatus extends into the semi-cylindrical concavity to substantially fill that concavity. The rotational mixer is divided into two wheels with outer paddles extending axially outwardly and inner paddles extending axially inwardly on either side of each wheel. Blades between the outer and inner paddles form impellers in the wheels to induce axial flow through the wheels in opposite directions. Stationary baffles fixed relative to the containment vessel are inclined toward the rotational mixer in the direction of rotation. The containment vessel may be of film and supported by a structural housing also having a semi-cylindrical concavity defined by the noosing bottom.
    • 一种具有容纳容器的气动生物反应器,其包括由容器底部限定的半圆柱形凹面。 混合装置包括旋转混合器,其围绕水平轴可旋转地安装在容纳容器内。 旋转混合器具有浮力驱动的混合腔,其通过旋转混合器下面的气体供给。 混合装置延伸到半圆柱形凹部中以基本上填充该凹部。 旋转混合器被分成两个轮子,其外侧叶片沿轴向向外延伸,内部桨叶在每个轮的任一侧上轴向向内延伸。 外桨叶和内桨叶之间的叶片在车轮中形成叶轮,以引起相反方向的轴向流动。 相对于安全壳固定的固定挡板在旋转方向上朝向旋转混合器倾斜。 容纳容器可以是薄膜,并且由也由具有限定的底部限定的半圆柱形凹部的结构外壳支撑。
    • 16. 发明授权
    • Pneumatic bioreactor
    • 气动生物反应器
    • US07713730B2
    • 2010-05-11
    • US11739659
    • 2007-04-24
    • J. Gregory ZeikusKyungnam KimThomas A. PostKeith E. Johnson
    • J. Gregory ZeikusKyungnam KimThomas A. PostKeith E. Johnson
    • C12M1/06
    • C12M27/06B01F3/04588B01F7/00308B01F7/00916B01F7/04B01F15/005B01F15/00545C12M27/20
    • A pneumatic bioreactor having a containment vessel which includes a semi-cylindrical concavity defined by the vessel bottom. A mixing apparatus includes a rotational mixer rotatably mounted within the containment vessel about a horizontal axis. The rotational mixer has buoyancy-driven mixing cavities which are fed by a gas supply beneath the rotational mixer. The mixing apparatus extends into the semi-cylindrical concavity to substantially fill that concavity. The rotational mixer is divided into two wheels with outer paddles extending axially outwardly and inner paddles extending axially inwardly on either side of each wheel. Blades between the outer and inner paddles form impellers in the wheels to induce axial flow through the wheels in opposite directions. Stationary baffles fixed relative to the containment vessel are inclined toward the rotational mixer in the direction of rotation. The containment vessel may be of film and supported by a structural housing also having a semi-cylindrical concavity defined by the housing bottom.
    • 一种具有容纳容器的气动生物反应器,其包括由容器底部限定的半圆柱形凹面。 混合装置包括旋转混合器,其围绕水平轴可旋转地安装在容纳容器内。 旋转混合器具有浮力驱动的混合腔,其通过旋转混合器下面的气体供给。 混合装置延伸到半圆柱形凹部中以基本上填充该凹部。 旋转混合器被分成两个轮子,其外侧叶片沿轴向向外延伸,内部桨叶在每个轮的任一侧上轴向向内延伸。 外桨叶和内桨叶之间的叶片在车轮中形成叶轮,以引起相反方向的轴向流动。 相对于安全壳固定的固定挡板在旋转方向上朝向旋转混合器倾斜。 安全壳可以是薄膜,并由具有由壳体底部限定的半圆柱形凹面的结构外壳支撑。
    • 17. 发明申请
    • Pneumatic Bioreactor
    • 气动生物反应器
    • US20080261299A1
    • 2008-10-23
    • US11739089
    • 2007-04-23
    • J. Gregory ZeikusKyungnam KimDavid S. Dickey
    • J. Gregory ZeikusKyungnam KimDavid S. Dickey
    • C12M1/02
    • C12M27/06
    • A pneumatic bioreactor having a containment vessel which includes a semi-cylindrical concavity defined by the vessel bottom. A mixing apparatus includes a rotational mixer rotatably mounted within the containment vessel about a horizontal axis. The rotational mixer has buoyancy-driven mixing cavities which are fed by a gas supply beneath the rotational mixer. The mixing apparatus extends into the semi-cylindrical concavity to substantially fill that concavity. The rotational mixer is divided into two wheels with outer paddles extending axially outwardly and inner paddles extending axially inwardly on either side of each ring. Blades between the outer and inner paddles form impellers in the wheels to induce axial flow through the rings in opposite directions. The containment vessel may be of film and supported by a structural housing also having a semi-cylindrical concavity defined by the housing bottom.
    • 一种具有容纳容器的气动生物反应器,其包括由容器底部限定的半圆柱形凹面。 混合装置包括旋转混合器,其围绕水平轴可旋转地安装在容纳容器内。 旋转混合器具有浮力驱动的混合腔,其通过旋转混合器下面的气体供给。 混合装置延伸到半圆柱形凹部中以基本上填充该凹部。 旋转混合器被分成两个轮,其外侧叶片沿轴向向外延伸,并且内部桨叶在每个环的任一侧上轴向向内延伸。 外桨叶和内桨叶之间的叶片在轮中形成叶轮以引起轴向流动通过环的相反方向。 安全壳可以是薄膜,并由具有由壳体底部限定的半圆柱形凹面的结构外壳支撑。