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11. 发明授权

US5514171A Pressure and heart movement sensor for heart stimulators 失效
标题翻译：用于心脏刺激器的压力和心脏运动传感器
公开(公告)号：US5514171A
公开(公告)日：1996-05-07
申请号：US271522
申请日：1994-07-07
申请人： Kurt Hoegnelid , Kenth-Ake-Sune Nilsson , Nils Holmstroem , Roland Heinze , Karin Ljungstroem , Pierre Westin
发明人： Kurt Hoegnelid , Kenth-Ake-Sune Nilsson , Nils Holmstroem , Roland Heinze , Karin Ljungstroem , Pierre Westin
IPC分类号： A61N1/365 , A61B5/03 , A61N1/37 , A61N1/05
CPC分类号： A61B5/03 , A61N1/3702
摘要： A pressure and heart movement sensor for a heart stimulator, includes an electrode system for implantation with an electrode cable containing at least two electrical conductors leading to electrode poles. A measurement device is arranged to measure an electrical quantity between the electrical conductors, which quantity varying according to the pressure applied to the electrode cable. Alternately, the electrode cable contains at least one electrical conductor, and the measurement device is arranged to measure the impedance between the conductor and ambient medium and to deliver an output signal, which varies according to the impedance measured, when the electrode cable is subjected to pressure.
摘要翻译：用于心脏刺激器的压力和心脏运动传感器包括用于注入电极电缆的电极系统，该电极电缆包含至少两个通向电极极的电导体。测量装置被布置成测量电导体之间的电量，该电量根据施加到电极电缆的压力而变化。替代地，电极电缆包含至少一个电导体，并且测量装置被布置成测量导体和环境介质之间的阻抗，并且当电极电缆经受时，传递根据测量的阻抗而变化的输出信号压力。

12. 发明授权

US5464429A Apparatus for producing heart defibrillation sequences from stimulation pulses and defibrillation shocks 失效
标题翻译：用于从刺激脉冲和除颤电击产生心脏除颤序列的装置
公开(公告)号：US5464429A
公开(公告)日：1995-11-07
申请号：US114357
申请日：1993-09-01
申请人： Sven-Erik Hedberg , Martin Obel , Kurt Hoegnelid
发明人： Sven-Erik Hedberg , Martin Obel , Kurt Hoegnelid
IPC分类号： A61N1/39 , A61N1/362
CPC分类号： A61N1/3962
摘要： An apparatus for producing heart defibrillation sequences formed of stimulation pulses and defibrillation shocks contains a unit for delivering pulses through an intracardiac or epicardiac electrode, normally for cardiac pacing, and defibrillator circuitry for delivering defibrillation shocks through defibrillation electrodes. The unit for delivering pacing pulses has an output stage which is capable of generating a stimulation pulse, delivered to the heart via the pacing electrode, having a higher energy content than a pacing pulse, but considerably less energy than a conventional defibrillation shock. A control unit is connected to the unit for delivering stimulation pulses and to the defibrillator circuitry for forming a defibrillation sequence consisting of stimulation pulses and defibrillation shocks. The control unit determines the timing for delivering the stimulation pulses and the defibrillation shocks.
摘要翻译：用于产生由刺激脉冲和除颤电击形成的心脏除颤序列的装置包含用于通过心脏或心外膜电极（通常用于心脏起搏）输送脉冲的单元，以及用于通过除颤电极输送除颤电击的除颤器电路。用于输送起搏脉冲的单元具有输出级，其能够产生刺激脉冲，经由起搏电极传递到心脏，具有比起搏脉冲更高的能量含量，但是比传统除颤电击显着更少的能量。控制单元连接到用于递送刺激脉冲的单元和去纤颤器电路，用于形成由刺激脉冲和除颤电击组成的除颤序列。控制单元确定输送刺激脉冲和除颤电击的时间。

13. 发明授权

US5458115A Detector for sensing events in living tissue 失效
标题翻译：用于感测活组织中的事件的检测器
公开(公告)号：US5458115A
公开(公告)日：1995-10-17
申请号：US152126
申请日：1993-11-16
申请人： Ake Sivard , Kurt Hoegnelid
发明人： Ake Sivard , Kurt Hoegnelid
IPC分类号： A61N1/365 , A61B5/0472
CPC分类号： A61N1/36507
摘要： A detector for sensing events in living tissue, such as electrical events in a heart, contains a microprocessor functioning as comparator which compares an input signal corresponding to electrical signals from the living tissue with a defined signal detection level, and an event is deemed to have occurred if the input signal exceeds the defined detection level. More reliable detection of events in the presence of noise is achieved by also providing an integrator which generates the input signal to the comparator by integrating electrical signals obtained from the tissue, the comparator then comparing the integrated signal with a detection level selected for use with the integrated signal.
摘要翻译：用于感测活体组织中的事件（例如心脏中的电事件）的检测器包含用作比较器的微处理器，其将对应于来自活体组织的电信号的输入信号与定义的信号检测水平进行比较，并且事件被认为具有如果输入信号超过定义的检测电平，则发生。通过还提供一种通过积分从组织获得的电信号向比较器产生输入信号的积分器来实现对噪声存在的事件的更可靠的检测，比较器然后将积分信号与所选择的与综合信号。

14. 发明授权

US5427112A Device for analyzing the function of a heart 失效
标题翻译：用于分析心脏功能的装置
公开(公告)号：US5427112A
公开(公告)日：1995-06-27
申请号：US51250
申请日：1993-04-23
申请人： Kjell Noren , Kurt Hoegnelid
发明人： Kjell Noren , Kurt Hoegnelid
IPC分类号： A61B5/0452 , A61N1/365 , A61B5/00
CPC分类号： A61N1/36585 , A61N1/36507
摘要： A device for analyzing the function of a heart, containing a measurement unit for generating a first measurement signal related to a first electrical or mechanical heart variable and an evaluation unit for evaluating the measurement signal, further contains a circuitry for generating a parameter signal related to a heart variable, the evaluation unit analyzing the related values for the measurement signal and the parameter signal. The device can be used for detecting a number of functional aberrations, such as bradycardia, tachyarrhythmia, retrograde conduction, ischemia and ectopia, and for controlling pacemakers and defibrillators.
摘要翻译：一种用于分析心脏功能的装置，包括用于产生与第一电气或机械心脏变量相关的第一测量信号的测量单元和用于评估测量信号的评估单元，还包括用于产生与心脏变量，评估单元分析测量信号和参数信号的相关值。该装置可用于检测许多功能异常，例如心动过缓，快速性心律失常，逆行传导，缺血和异位，以及用于控制起搏器和除颤器。

15. 发明授权

US5385576A Method for detecting ventricular fibrillation and apparatus for detecting and treating ventricular fibrillation 失效
标题翻译：心室颤动检测方法及心室颤动检测及治疗仪器
公开(公告)号：US5385576A
公开(公告)日：1995-01-31
申请号：US101727
申请日：1993-08-04
申请人： Kjell Noren , Pia Hagel , Kurt Hoegnelid
发明人： Kjell Noren , Pia Hagel , Kurt Hoegnelid
IPC分类号： A61B5/05 , A61B5/053 , A61N1/365 , A61N1/39
CPC分类号： A61N1/36521 , A61B5/0535 , A61N1/3962 , A61N1/395
摘要： In a method and apparatus for detecting ventricular fibrillation, a measured impedance signal, dependent on the blood volume in the heart, is evaluated, and ventricular fibrillation is assumed to be present if the level of the measured impedance signal falls below a predetermined threshold. This is based on the perception that as the heart fills with blood, given the presence of ventricular fibrillation, the level of the measured impedance signal will decrease. The apparatus also includes circuitry for treating the detected ventricular fibrillation.
摘要翻译：在用于检测心室颤动的方法和装置中，评估取决于心脏中的血液体积的测量阻抗信号，并且如果测得的阻抗信号的电平低于预定阈值，则认为存在心室颤动。这是基于以下认识：当心脏充满血液时，鉴于心室颤动的存在，测得的阻抗信号的水平将降低。该装置还包括用于治疗所检测的心室颤动的电路。

16. 发明授权

US5353801A Method for processing an electrical signal, particularly a signal derived from a heart 失效
标题翻译：用于处理电信号的方法，特别是从心脏得到的信号
公开(公告)号：US5353801A
公开(公告)日：1994-10-11
申请号：US100043
申请日：1993-07-30
申请人： Kurt Hoegnelid
发明人： Kurt Hoegnelid
IPC分类号： H03M3/02 , G06F17/00 , H04B14/06 , A61B5/00
CPC分类号： A61B5/04325 , A61B5/7232
摘要： For compressing an electrical signal, such as a cardiac signal, converted by delta modulation into a binary operational sign signal, four data words are generated in the sequence of the appearance of four possible statuses, the four data words respectively defining the status and its duration. The statuses are defined in that the signal has a positive, minimum steepness during a minimum duration in a first status and has a negative minimum steepness in a second status. For a flatter signal curve, third and fourth statuses are respectively defined in which the signal rises or drops by a defined amount during the status duration.
摘要翻译：为了将通过增量调制转换的电信号（例如心脏信号）压缩为二进制操作符号信号，以四种可能状态的出现顺序生成四个数据字，四个数据字分别定义状态及其持续时间。状态被定义为信号在第一状态的最小持续时间内具有正的最小陡度，并且在第二状态中具有负的最小陡度。对于较平坦的信号曲线，分别定义第三和第四状态，其中信号在状态持续时间期间上升或下降定义的量。

17. 发明授权

US5016632A Medical device and method for stimulating a physiological event in a patient with a stimulation intensity automatically adapting to the physical activity of the patient 失效
标题翻译：用于刺激患者的生理事件的医疗装置和方法，所述刺激强度自动适应患者的身体活动
公开(公告)号：US5016632A
公开(公告)日：1991-05-21
申请号：US572417
申请日：1990-08-27
申请人： Kurt Hoegnelid , Jan Ljungstroem
发明人： Kurt Hoegnelid , Jan Ljungstroem
IPC分类号： A61N1/36 , A61N1/365
CPC分类号： A61N1/36542
摘要： An implantable medical device for stimulating a physiological event in a patient at a stimulation intensity includes circuitry for adapting the stimulation intensity to the physical activity of the patient with refernce to a parameter contained within a physical activity signal obtained from a sensor. Circuitry is also provided for reducing, under certain circumstances, the sensitivity for the parameter of the physical activity signal which is used to adapt the stimulatin intensity. Reducing the sensitivity ensues dependent on the time over which the stimulation intensity is below a defined threshold. A method for operating the device is also disclosed.
摘要翻译：用于以刺激强度刺激患者的生理事件的可植入医疗装置包括用于根据从传感器获得的身体活动信号中包含的参数使刺激强度适应于患者的身体活动的电路。还提供了电路，用于在某些情况下减少用于适应刺激素强度的身体活动信号的参数的灵敏度。降低灵敏度取决于刺激强度低于规定阈值的时间。还公开了一种操作该装置的方法。

18. 发明授权

US5662687A Implantable heart defibrillator 失效
标题翻译：植入心脏除颤器
公开(公告)号：US5662687A
公开(公告)日：1997-09-02
申请号：US407046
申请日：1995-03-17
申请人： Sven-Erik Hedberg , Martin Obel , Kurt Hoegnelid
发明人： Sven-Erik Hedberg , Martin Obel , Kurt Hoegnelid
IPC分类号： A61N1/39
CPC分类号： A61N1/3956
摘要： An implantable heart defibrillator includes a pulse generator controlled by a control unit for emitting defibrillation pulses. The pulse generator is controllable to emit a number of low-energy defibrillation pulses, having a lower pulse amplitude and a shorter pulse duration than a conventional defibrillation pulse, with the total energy in the number of low-energy defibrillation pulses being less than the energy in a conventional defibrillation pulse. Each pulse in the number of low-energy defibrillation pulses, however, contains enough energy to depolarize heart cells oriented favorably in relation to the direction of the electrical field of the low-energy defibrillation pulse.
摘要翻译：可植入心脏除颤器包括由用于发射除颤脉冲的控制单元控制的脉冲发生器。脉冲发生器是可控制的，以发射多个低能量除颤脉冲，其具有比常规除颤脉冲更低的脉冲幅度和更短的脉冲持续时间，其中低能量除颤脉冲数量的总能量小于能量在常规除颤脉冲中。然而，以低能量除颤脉冲数量的每个脉冲包含足够的能量来使相对于低能除颤脉冲的电场方向有利地定向的心脏细胞去极化。

19. 发明授权

US5458630A Medical electrode device having a non-gaseous fluid conductor 失效
标题翻译：具有非气态流体导体的医用电极装置
公开(公告)号：US5458630A
公开(公告)日：1995-10-17
申请号：US226337
申请日：1994-04-12
申请人： Kurt Hoegnelid , Heinz Neubauer , Jens Wolf
发明人： Kurt Hoegnelid , Heinz Neubauer , Jens Wolf
IPC分类号： A61B5/0408 , A61B5/0478 , A61B5/0492 , A61N1/05 , A61N1/362 , H01B1/20 , H01B1/22 , H01B1/24 , A61N1/04
CPC分类号： A61N1/05 , H01B1/20 , H01B1/22 , H01B1/24
摘要： A medical electrode device of the type suitable for delivering therapeutic electrical energy in vivo to tissue from an implanted pulse generator, includes a sleeve containing a conductor which is a non-metallic, non-gaseous fluid conductor. The non-gaseous, non-metallic fluid conductor may be a conductive gel or an electrolytic liquid.
摘要翻译：适合于从植入脉冲发生器向组织递送治疗电能的类型的医疗电极装置包括包含非金属非气态流体导体的导体的套管。非气态非金属流体导体可以是导电凝胶或电解液体。

20. 发明授权

US5433731A Mechanical defibrillator and method for defibrillating a heart 失效
标题翻译：机械除颤器和除颤心脏的方法
公开(公告)号：US5433731A
公开(公告)日：1995-07-18
申请号：US210467
申请日：1994-03-21
申请人： Kurt Hoegnelid , Liliane Wecke , Kenth-Ake-Sune Nilsson , Jan Ljungstroem
发明人： Kurt Hoegnelid , Liliane Wecke , Kenth-Ake-Sune Nilsson , Jan Ljungstroem
IPC分类号： A61N1/365 , A61N1/39
CPC分类号： A61N1/3956
摘要： An implantable heart defibrillator and a method for defibrillating a heart, employ a shock pulse generator for delivering a defibrillation shock to a heart, the delivered energy being mechanical. The shock pulse generator includes an electromechanical energy converter which generates, e.g., pressure, by means of a piezoelement, in a pressure chamber. Pressure is transmitted by a fluid in an electrode devised like a hydraulic line to a balloon-like electrode head in contact with heart tissue. The generated pressure causes the electrode head to expand and deliver a mechanical shock to the heart corresponding to the pressure.
摘要翻译：可植入心脏除颤器和用于除心脏的方法，使用冲击脉冲发生器将心脏的除颤电击递送，所输送的能量是机械的。冲击脉冲发生器包括机电能量转换器，其通过压电元件在压力室中产生例如压力。压力由设计为液压管线的电极中的流体传播到与心脏组织接触的气球状电极头。产生的压力导致电极头膨胀并且相应于压力向心脏递送机械冲击。

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