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11. 发明授权

US08147759B2 Automated protein analyzer 有权
标题翻译：自动蛋白分析仪
公开(公告)号：US08147759B2
公开(公告)日：2012-04-03
申请号：US11846598
申请日：2007-08-29
申请人： Michael J. Collins, Sr. , Joseph J. Lambert , Timothy A. Zawatsky , David L. Herman
发明人： Michael J. Collins, Sr. , Joseph J. Lambert , Timothy A. Zawatsky , David L. Herman
IPC分类号： G01N21/78
CPC分类号： G01N33/6839 , G01N1/286 , G01N21/17 , G01N21/251 , G01N33/12 , G01N33/6803 , G01N35/1095 , G01N2001/4088 , Y10T436/10 , Y10T436/105831 , Y10T436/25
摘要： A direct rapid automated protein analyzer is disclosed. The protein analyzer includes means for reducing protein samples to small particles, a reaction vessel in material transfer communication with the homogenizer, a reservoir for binding dye composition in fluid communication with the reaction vessel, a metering pump in fluid communication with the reservoir and the reaction vessel for distributing discrete predetermined amounts of a binding dye composition to the reaction vessel, a filter in fluid communication with the reaction vessel for separating solids from filtrate after a dye binding reaction has taken place in the reaction vessel, and a calorimeter in fluid communication with the filter and the reaction vessel for measuring the absorbance of the filtrate from the reaction vessel and the filter. The rapid analyzer can be used in conjunction with a kit that includes a sample cup for mixing a protein sample with a dye-binding solution and a filter holder for being positioned in the sample cup. The filter holder includes a filter media and a depending spout below the filter media that reaches bottom portions of the cup when the filter media is positioned above the cup. The kit can also include dye concentrate solution.
摘要翻译：公开了一种直接快速自动蛋白质分析仪。蛋白质分析仪包括将蛋白质样品还原成小颗粒的装置，与均化器材料转移连通的反应容器，用于结合与反应容器流体连通的染料组合物的储存器，与储存器流体连通的计量泵和反应用于将分散的预定量的结合染料组合物分配到反应容器中的过滤器，与反应容器流体连通的过滤器，用于在反应容器中发生染料结合反应后从滤液中分离固体;以及色度计，其与过滤器和用于测量来自反应容器和过滤器的滤液的吸光度的反应容器。快速分析仪可以与包括用于将蛋白质样品与染料结合溶液混合的样品杯和用于定位在样品杯中的过滤器保持器的试剂盒结合使用。当过滤介质位于杯子上方时，过滤器保持器包括过滤介质和在过滤介质下方到达杯的底部的垂直喷口。该试剂盒还可以包括染料浓缩液。

12. 发明申请

US20120074136A1 Pressure Stepped Microwave Assisted Digestion 审中-公开
标题翻译：压力步进微波辅助消化
公开(公告)号：US20120074136A1
公开(公告)日：2012-03-29
申请号：US13239447
申请日：2011-09-22
申请人： David A. Barclay , Joseph J. Lambert , William E. Jennings , David L. Herman
发明人： David A. Barclay , Joseph J. Lambert , William E. Jennings , David L. Herman
IPC分类号： H05B6/64
CPC分类号： G01N1/44 , B01J19/126 , B01J2219/0801 , B01J2219/0871 , B01J2219/0877 , B01J2219/089 , B01J2219/1215 , B01J2219/1233 , B01J2219/1236 , B01J2219/1242 , B01J2219/1275 , H05B6/6447 , H05B6/806
摘要： An instrument and method for high pressure microwave assisted chemistry are disclosed. The method includes the steps of applying microwave radiation to a sample in a sealed vessel while measuring the temperature and pressure generated inside the vessel and until the measured pressure reaches a designated set point, opening the vessel to release gases until the pressure inside the vessel reaches a lower set point, closing the vessel, and repeating the steps of opening the vessel at designated pressure set points and closing the vessel at designated pressure set points to the sample until the sample reaction reaches a designated high temperature. Microwave energy can be applied continuously or intermittently during the opening and closing steps. Among other items, the instrument includes pressure and temperature sensors and means for opening and closing the vessel at the set points.
摘要翻译：公开了一种用于高压微波辅助化学的仪器和方法。该方法包括以下步骤：在测量容器内部产生的温度和压力的同时，将测量的压力达到指定的设定点，向容器中的样品施加微波辐射，打开容器释放气体，直到容器内的压力达到下部设定点，关闭容器，并重复在指定的压力设定点打开容器的步骤，并在指定的压力设定点关闭容器至样品，直到样品反应达到指定的高温。微波能量可以在打开和关闭步骤期间连续或间歇地施加。在其他项目中，仪器包括压力和温度传感器以及用于在设定点打开和关闭容器的装置。

13. 发明申请

US20090061522A1 Automated Protein Analyzer 有权
标题翻译：自动蛋白分析仪
公开(公告)号：US20090061522A1
公开(公告)日：2009-03-05
申请号：US11846598
申请日：2007-08-29
申请人： Michael J. Collins, SR. , Joseph J. Lambert , Timothy A. Zawatsky , David L. Herman
发明人： Michael J. Collins, SR. , Joseph J. Lambert , Timothy A. Zawatsky , David L. Herman
IPC分类号： G01N33/02 , B01J19/00 , B01L3/00 , G01N33/68 , G01N21/01
CPC分类号： G01N33/6839 , G01N1/286 , G01N21/17 , G01N21/251 , G01N33/12 , G01N33/6803 , G01N35/1095 , G01N2001/4088 , Y10T436/10 , Y10T436/105831 , Y10T436/25
摘要： A direct rapid automated protein analyzer is disclosed. The protein analyzer includes means for reducing protein samples to small particles, a reaction vessel in material transfer communication with the homogenizer, a reservoir for binding dye composition in fluid communication with the reaction vessel, a metering pump in fluid communication with the reservoir and the reaction vessel for distributing discrete predetermined amounts of a binding dye composition to the reaction vessel, a filter in fluid communication with the reaction vessel for separating solids from filtrate after a dye binding reaction has taken place in the reaction vessel, and a calorimeter in fluid communication with the filter and the reaction vessel for measuring the absorbance of the filtrate from the reaction vessel and the filter. The rapid analyzer can be used in conjunction with a kit that includes a sample cup for mixing a protein sample with a dye-binding solution and a filter holder for being positioned in the sample cup. The filter holder includes a filter media and a depending spout below the filter media that reaches bottom portions of the cup when the filter media is positioned above the cup. The kit can also include dye concentrate solution.
摘要翻译：公开了一种直接快速自动蛋白质分析仪。蛋白质分析仪包括将蛋白质样品还原成小颗粒的装置，与均化器材料转移连通的反应容器，用于结合与反应容器流体连通的染料组合物的储存器，与储存器流体连通的计量泵和反应用于将分散的预定量的结合染料组合物分配到反应容器中的过滤器，与反应容器流体连通的过滤器，用于在反应容器中发生染料结合反应后从滤液中分离固体;以及色度计，其与过滤器和用于测量来自反应容器和过滤器的滤液的吸光度的反应容器。快速分析仪可以与包括用于将蛋白质样品与染料结合溶液混合的样品杯和用于定位在样品杯中的过滤器保持器的试剂盒结合使用。当过滤介质位于杯子上方时，过滤器保持器包括过滤介质和在过滤介质下方到达杯的底部的垂直喷口。该试剂盒还可以包括染料浓缩液。

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