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11. 发明授权

US06350262B1 Method and apparatus for applying thermal energy to tissue asymetrically 失效
标题翻译：将热能不对称地施加到组织的方法和装置
公开(公告)号：US06350262B1
公开(公告)日：2002-02-26
申请号：US09547988
申请日：2000-04-12
申请人： John E. Ashley
发明人： John E. Ashley
IPC分类号： A61B1804
CPC分类号： A61B18/08 , A61B18/1482 , A61B2018/00023 , A61B2018/00029 , A61B2018/00047 , A61B2018/00821
摘要： Systems and methods are described for treating tissue with thermal energy while minimizing the amount of thermal energy to which adjacent tissue is exposed. A surgical instrument for delivering thermal energy to a section of tissue during percutaneous surgery, includes: an elongated shaft having a proximal end and a distal end; and a split tip electrode coupled to said distal end, said split tip electrode i) including a first component and a second component coupled to said first component, and ii) defining a principle axis. The thermal energy is delivered to said section of tissue so as to heat said section of tissue asymmetrically with regard to said principle axis of said split tip electrode. The systems and methods provide advantages in that thermal energy can be directed to one side of the split tip so that a first of two juxtaposed areas of a surgical site can be heated while a second of the two juxtaposed layers is substantially not heated. In alternate embodiments a portion of the site may be actively cooled while an adjacent portion of the site may be actively cooled.
摘要翻译：描述了用热处理组织同时最小化相邻组织暴露的热能量的系统和方法。用于在经皮手术期间将热能递送到组织的一部分的手术器械包括：具有近端和远端的细长轴; 以及耦合到所述远端的分离尖端电极，所述分离尖端电极i）包括耦合到所述第一部件的第一部件和第二部件，以及ii）限定主轴线。将热能输送到组织的所述部分，以便相对于所述分裂尖端电极的所述主轴线不对称地加热组织的所述部分。该系统和方法提供的优点在于，热能可以被引导到分裂尖端的一侧，使得可以加热手术部位的两个并置的区域中的第一个，而两个并置的层中的第二个基本上不被加热。在替代实施例中，站点的一部分可以被主动冷却，同时站点的相邻部分可以被主动冷却。

12. 发明授权

US06258086B1 Catheter for delivery of energy to a surgical site 有权
标题翻译：导管将能量输送到手术部位
公开(公告)号：US06258086B1
公开(公告)日：2001-07-10
申请号：US09272806
申请日：1999-03-19
申请人： John E. Ashley , Hugh R. Sharkey , Joel Saal , Jeff A. Saal
发明人： John E. Ashley , Hugh R. Sharkey , Joel Saal , Jeff A. Saal
IPC分类号： A61B1818
CPC分类号： A61B18/082 , A61B10/02 , A61B17/00491 , A61B17/1671 , A61B17/29 , A61B17/320016 , A61B17/3203 , A61B17/3421 , A61B17/3496 , A61B18/00 , A61B18/14 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/24 , A61B34/20 , A61B2017/00022 , A61B2017/00084 , A61B2017/0011 , A61B2017/00119 , A61B2017/00261 , A61B2017/00274 , A61B2017/003 , A61B2017/00336 , A61B2017/00455 , A61B2017/00867 , A61B2017/22044 , A61B2017/22049 , A61B2017/22082 , A61B2017/22087 , A61B2017/2905 , A61B2017/2927 , A61B2017/320008 , A61B2017/320044 , A61B2017/32113 , A61B2017/3445 , A61B2017/3488 , A61B2018/00011 , A61B2018/00267 , A61B2018/00434 , A61B2018/0044 , A61B2018/00547 , A61B2018/00625 , A61B2018/00654 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/046 , A61B2018/1266 , A61B2018/1405 , A61B2018/1407 , A61B2018/1412 , A61B2018/1425 , A61B2018/1435 , A61B2018/1455 , A61B2018/1472 , A61B2018/1807 , A61B2090/0454 , A61B2090/061 , A61B2090/064 , A61B2090/3937 , A61B2217/005 , A61B2217/007 , A61B2218/002 , A61B2218/007 , A61F2/442 , A61F2002/30677 , A61F2007/0298 , A61M25/0144 , A61M25/0155 , A61M25/0158 , A61M2025/0063 , A61M2025/0064 , A61M2025/0163 , A61N1/06 , A61N1/40
摘要： A catheter for delivering energy to a surgical site is disclosed. The catheter includes at a proximal end a handle and at a distal end a probe. The catheter includes at least one energy delivery device and an activation element. The at least one energy delivery device is located at the distal end of the catheter to deliver energy to portions of the surgical site. The activation element is located at the distal end of the catheter, to transition the probe from a linear to a multi-dimensional shape, within the surgical site. Methods for deploying the probe from the linear to multi-dimensional shape are disclosed.
摘要翻译：公开了一种用于向外科手术部位输送能量的导管。导管在近端处包括手柄，并且在远端处包括探针。导管包括至少一个能量输送装置和激活元件。所述至少一个能量输送装置位于所述导管的远端，以将能量传递到手术部位的部分。激活元件位于导管的远端，以将探针从线性过渡到多维形状，在手术部位内。公开了将探针从线性部分展开到多维形状的方法。

13. 发明申请

US20130310837A1 POWERED TISSUE MODIFICATION DEVICES AND METHODS 有权
标题翻译：动力组织修改装置和方法
公开(公告)号：US20130310837A1
公开(公告)日：2013-11-21
申请号：US13913801
申请日：2013-06-10
申请人： Vahid SAADAT , Jeffery L. BLEICH , Kenneth J. MICHLITSCH , John E. ASHLEY
发明人： Vahid SAADAT , Jeffery L. BLEICH , Kenneth J. MICHLITSCH , John E. ASHLEY
IPC分类号： A61B17/16
CPC分类号： A61B17/1659 , A61B17/1671
摘要： A device for modifying tissue in a spine may include: a shaft having a proximal portion and a distal portion, the distal portion having dimensions which allow it to be passed into an epidural space of the spine and between target and non-target tissues; at least one distal force application member extending from the distal portion of the shaft and configured to facilitate application of at least one of anchoring force and tensioning force to the shaft; at least one movable tissue modifying member coupled with the shaft at or near its distal portion; at least one drive member coupled with the at least one tissue modifying member to activate the at least one tissue modifying member; and at least one power transmission member coupled with the at least one drive member to deliver power to the at least one drive member.
摘要翻译：用于修改脊柱中的组织的装置可以包括：具有近端部分和远侧部分的轴，所述远端部分具有允许其进入脊柱的硬膜外腔中以及靶和非靶组织之间的尺寸; 至少一个远端力施加构件，其从所述轴的远侧部分延伸并且构造成便于将锚固力和张紧力中的至少一个施加到所述轴; 至少一个可动组织修改构件，其在远端部分处或其附近与所述轴联接; 至少一个驱动构件与所述至少一个组织修改构件联接以激活所述至少一个组织修改构件; 以及与所述至少一个驱动构件联接的至少一个动力传递构件，以向所述至少一个驱动构件输送动力。

14. 发明申请

US20120136389A1 SUTURE LOCK 审中-公开
标题翻译：舒服锁
公开(公告)号：US20120136389A1
公开(公告)日：2012-05-31
申请号：US13365933
申请日：2012-02-03
申请人： John E. Ashley , David F. Lyons
发明人： John E. Ashley , David F. Lyons
IPC分类号： A61B17/04
CPC分类号： A61B17/0487 , A61B2017/0496 , A61B2017/06028 , Y10T24/3918
摘要： A suture lock according to the present invention provides sufficiently secures a suture thread in place in a quick and efficient manner. It eliminates the need for a laproscopic surgeon to tie complex or multi-step knots. The suture lock generally comprises a suture lock body having a suture channel that allows a suture thread to be drawn into the suture lock body. A plurality of teeth extends into an opening of the suture channel in such a manner that an inserted suture thread will be locked in place. In addition, a guide portion eases insertion of a suture thread free end by simplifying relative rotational adjustment of the lock. An embodiment of the present invention may be fabricated from a material or materials that naturally dissolve within the human body.
摘要翻译：根据本发明的缝线锁以快速有效的方式提供足够的缝合线固定到位。它不需要腹腔外科医生来结合复杂或多步骤结。缝线锁通常包括具有缝线通道的缝线锁体，其允许缝合线被拉入缝线锁体。多个齿以插入的缝合线被锁定就位的方式延伸到缝线通道的开口中。此外，引导部分通过简化锁的相对旋转调节来简化缝合线自由端的插入。本发明的一个实施例可以由天然溶解在人体内的材料或材料制成。

15. 发明申请

US20100145456A1 Lockable spinal implant 有权
公开(公告)号：US20100145456A1
公开(公告)日：2010-06-10
申请号：US12384622
申请日：2009-04-07
申请人： Philip J. Simpson , David G. Matsuura , Walter Dean Gillespie , George A. Mansfield, III , John E. Ashley
发明人： Philip J. Simpson , David G. Matsuura , Walter Dean Gillespie , George A. Mansfield, III , John E. Ashley
IPC分类号： A61F2/44
CPC分类号： A61F2/44 , A61F2/30742 , A61F2/442 , A61F2/4455 , A61F2002/30079 , A61F2002/3008 , A61F2002/30133 , A61F2002/30365 , A61F2002/30405 , A61F2002/30476 , A61F2002/30484 , A61F2002/30499 , A61F2002/30505 , A61F2002/30514 , A61F2002/30522 , A61F2002/30525 , A61F2002/3055 , A61F2002/30579 , A61F2002/30581 , A61F2002/30589 , A61F2002/30601 , A61F2002/30841 , A61F2002/482 , A61F2002/485 , A61F2210/009 , A61F2220/0025 , A61F2220/0033 , A61F2230/0015 , A61F2250/0007 , A61F2250/0069 , A61F2250/0098 , A61F2310/00017 , A61F2310/00023
摘要： A spinal implant which is configured to be deployed between adjacent vertebral bodies. The implant has at least one extendable support element with a retracted configuration to facilitate deployment of the implant and an extended configuration so as to expand the implant and effectively distract the disc space, stabilize the motion segments and eliminate pathologic spine motion. Angular deformities can also be corrected, and natural curvatures restored. Preferably, the implant has a minimal dimension in its unexpanded state that is smaller than the dimensions of the neuroforamen through which it typically passes to be deployed within the intervertebral space. The implant is provided with a locking system preferably having a plurality of locking elements to lock the implant in an extended configuration.

16. 发明申请

US20090156958A1 DEVICES AND METHODS FOR PERCUTANEOUS ENERGY DELIVERY 审中-公开
标题翻译：用于经济能源交付的设备和方法
公开(公告)号：US20090156958A1
公开(公告)日：2009-06-18
申请号：US12055258
申请日：2008-03-25
申请人： Bankim H. MEHTA , John E. ASHLEY , Scott A. McGILL
发明人： Bankim H. MEHTA , John E. ASHLEY , Scott A. McGILL
IPC分类号： A61F7/12 , A61N1/05 , A61N7/00 , A61B5/01 , A61N5/06
CPC分类号： A61B18/203 , A61B18/02 , A61B18/08 , A61B18/1477 , A61B18/18 , A61B2017/00084 , A61B2018/00452 , A61B2018/00464 , A61B2018/0047 , A61B2018/00994 , A61B2018/1425 , A61B2018/143 , A61B2018/2005 , A61N1/05 , A61N1/328
摘要： The invention provides a system and method for percutaneous energy delivery in an effective, manner using one or more probes. Additional variations of the system include array of probes configured to minimize the energy required to produce the desired effect.
摘要翻译：本发明提供了一种使用一个或多个探针以有效方式进行经皮能量输送的系统和方法。该系统的附加变体包括被配置为最小化产生所需效果所需的能量的探针阵列。

17. 发明申请

US20090076546A1 Suture lock 失效
标题翻译：缝合锁
公开(公告)号：US20090076546A1
公开(公告)日：2009-03-19
申请号：US12231748
申请日：2008-09-05
申请人： John E. Ashley , David F. Lyons
发明人： John E. Ashley , David F. Lyons
IPC分类号： A61B17/04
CPC分类号： A61B17/0487 , A61B2017/0496 , A61B2017/06028 , Y10T24/3918
摘要： A suture lock according to the present invention provides sufficiently secures a suture thread in place in a quick and efficient manner. It eliminates the need for a laproscopic surgeon to tie complex or multi-step knots. The suture lock generally comprises a suture lock body having a suture channel that allows a suture thread to be drawn into the suture lock body. A plurality of teeth extends into an opening of the suture channel in such a manner that an inserted suture thread will be locked in place. In addition, a guide portion eases insertion of a suture thread free end by simplifying relative rotational adjustment of the lock. An embodiment of the present invention may be fabricated from a material or materials that naturally dissolve within the human body.
摘要翻译：根据本发明的缝线锁以快速有效的方式提供足够的缝合线固定到位。它不需要腹腔外科医生来结合复杂或多步骤结。缝线锁通常包括具有缝线通道的缝线锁体，其允许缝合线被拉入缝线锁体。多个齿以插入的缝合线被锁定就位的方式延伸到缝线通道的开口中。此外，引导部分通过简化锁的相对旋转调节来简化缝合线自由端的插入。本发明的一个实施例可以由天然溶解在人体内的材料或材料制成。

18. 发明授权

US06757565B2 Electrosurgical instrument having a predetermined heat profile 失效
标题翻译：具有预定热分布的电外科器械
公开(公告)号：US06757565B2
公开(公告)日：2004-06-29
申请号：US10071470
申请日：2002-02-08
申请人： Hugh R. Sharkey , John E. Ashley , Kobi Iki
发明人： Hugh R. Sharkey , John E. Ashley , Kobi Iki
IPC分类号： A61F712
CPC分类号： A61B18/148
摘要： An electrosurgical instrument is provided, having a holding formation, an elongated probe, an electrode, and a conductor. The elongated probe is connected to and extends from the holding formation. The electrode is located on an end of the elongated probe opposing the holding formation, and has a leading edge and a face. The electrode is locatable so that the face is substantially in a horizontal plane and the leading edge is above the horizontal plane. The conductor extends along the elongated probe and has a portion connected to the electrode to provide RF power thereto. The electrode creates a temperature profile with a temperature adjacent to the leading edge being higher than a temperature adjacent to the face.
摘要翻译：提供了一种具有保持结构，细长探针，电极和导体的电外科器械。细长的探针连接到保持结构并从保持结构延伸。电极位于与保持结构相对的细长探针的端部上，并且具有前缘和面。电极是可定位的，使得所述面基本上处于水平面并且前缘在水平面之上。导体沿着细长的探针延伸并且具有连接到电极的部分以向其提供RF功率。电极产生温度曲线，其中与前缘相邻的温度高于与面相邻的温度。

19. 发明授权

US06749605B2 Catheter for delivery of energy to a surgical site 有权
标题翻译：导管将能量输送到手术部位
公开(公告)号：US06749605B2
公开(公告)日：2004-06-15
申请号：US09776186
申请日：2001-02-01
申请人： John E. Ashley , Hugh R. Sharkey , Joel Saal , Jeffrey A. Saal
发明人： John E. Ashley , Hugh R. Sharkey , Joel Saal , Jeffrey A. Saal
IPC分类号： A61B1818
CPC分类号： A61B18/082 , A61B10/02 , A61B17/00491 , A61B17/1671 , A61B17/29 , A61B17/320016 , A61B17/3203 , A61B17/3421 , A61B17/3496 , A61B18/00 , A61B18/14 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/24 , A61B34/20 , A61B2017/00022 , A61B2017/00084 , A61B2017/0011 , A61B2017/00119 , A61B2017/00261 , A61B2017/00274 , A61B2017/003 , A61B2017/00336 , A61B2017/00455 , A61B2017/00867 , A61B2017/22044 , A61B2017/22049 , A61B2017/22082 , A61B2017/22087 , A61B2017/2905 , A61B2017/2927 , A61B2017/320008 , A61B2017/320044 , A61B2017/32113 , A61B2017/3445 , A61B2017/3488 , A61B2018/00011 , A61B2018/00267 , A61B2018/00434 , A61B2018/0044 , A61B2018/00547 , A61B2018/00625 , A61B2018/00654 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/046 , A61B2018/1266 , A61B2018/1405 , A61B2018/1407 , A61B2018/1412 , A61B2018/1425 , A61B2018/1435 , A61B2018/1455 , A61B2018/1472 , A61B2018/1807 , A61B2090/0454 , A61B2090/061 , A61B2090/064 , A61B2090/3937 , A61B2217/005 , A61B2217/007 , A61B2218/002 , A61B2218/007 , A61F2/442 , A61F2002/30677 , A61F2007/0298 , A61M25/0144 , A61M25/0155 , A61M25/0158 , A61M2025/0063 , A61M2025/0064 , A61M2025/0163 , A61N1/06 , A61N1/40
摘要： A catheter for delivering energy to a surgical site is disclosed. The catheter includes at a proximal end a handle and at a distal end a probe. The catheter includes at least one energy delivery device and an activation element. The at least one energy delivery device is located at the distal end of the catheter to deliver energy to portions of the surgical site. The activation element is located at the distal end of the catheter, to transition the probe from a linear to a multi-dimensional shape, within the surgical site. Methods for deploying the probe from the linear to multi-dimensional shape are disclosed. In another embodiment of the invention, the catheter includes a heating element fabricated on a substrate by photo-etching to deliver thermal energy to portions of the surgical site. In another embodiment of the invention, the catheter includes an energy delivery element, a tip and a blade. The energy delivery element is located at the distal end of the catheter to deliver energy to portions of the intervertebral disc. The blade is positioned within a first lumen of the tip and is extensible beyond the tip, to cut selected portions within the intervertebral disc. In another embodiment of the invention, a catheter includes both energy and material transfer elements and an interface on the handle thereof. The interface couples the energy delivery element and the material transfer element to external devices for energy and material transfer to and from the intervertebral disc.
摘要翻译：公开了一种用于向外科手术部位输送能量的导管。导管在近端处包括手柄，并且在远端处包括探针。导管包括至少一个能量输送装置和激活元件。所述至少一个能量输送装置位于所述导管的远端，以将能量传递到手术部位的部分。激活元件位于导管的远端，以将探针从线性过渡到多维形状，在手术部位内。公开了将探针从线性部分展开到多维形状的方法。在本发明的另一个实施例中，导管包括通过光蚀刻在基底上制造的加热元件，以将热能传递到手术部位的部分。在本发明的另一个实施例中，导管包括能量输送元件，尖端和一个刀片。能量输送元件位于导管的远端，以将能量传递给椎间盘的部分。刀片定位在尖端的第一内腔内并且可延伸超过尖端，以切割椎间盘内的所选部分。在本发明的另一个实施例中，导管包括能量和材料转移元件以及手柄上的界面。该界面将能量输送元件和材料传递元件耦合到外部装置，以将能量和材料转移到椎间盘和从椎间盘传递。

20. 发明授权

US06699244B2 Electrosurgical instrument having a chamber to volatize a liquid 有权
标题翻译：电外科器械具有使液体挥发的室
公开(公告)号：US06699244B2
公开(公告)日：2004-03-02
申请号：US10124954
申请日：2002-04-17
申请人： J. Remberto Carranza , Hugh R. Sharkey , John E. Ashley , Gary S. Fanton
发明人： J. Remberto Carranza , Hugh R. Sharkey , John E. Ashley , Gary S. Fanton
IPC分类号： A61B1814
CPC分类号： A61B18/148 , A61B18/1482 , A61B18/1492 , A61B2017/320008 , A61B2018/00434 , A61B2018/00625 , A61B2018/00654 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/1472 , A61B2218/002 , A61N1/06 , A61N1/40
摘要： An electrosurgical instrument is provided which includes a holding formation, a probe shaft, an electric conductor, and a probe tip. The probe shaft is secured to the holding formation and has an elongated section extending therefrom. The electric conductor extends along the elongated section. The probe tip is located on a distal end of the probe shaft opposing the holding formation. The probe tip defines a volatization chamber with a mouth out of the probe tip. The probe tip includes an electrode, to which RF current is provided through the electric conductor. The electrode heats an area adjacent to the probe tip. The electrode also heats a liquid in the first volatization chamber to evaporate the liquid into a vapor pocket that ejects from the first volatization chamber through the mouth out of the probe tip. A pump effect is created so that the liquid maintains the probe tip at a more stable temperature.
摘要翻译：提供了一种电外科器械，其包括保持结构，探针轴，电导体和探针尖端。探头轴固定在保持结构上，并具有从其延伸的细长部分。电导体沿着细长部分延伸。探针尖端位于与保持结构相对的探针轴的远端上。探针尖端限定了具有探针尖端的口的挥发室。探针尖端包括电极，通过电导体提供RF电流。电极加热与探针尖端相邻的区域。电极还加热第一挥发室中的液体以将液体蒸发成从第一挥发室通过探针尖端喷出的蒸气袋。产生泵效应，使得液体将探针尖端保持在更稳定的温度。

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