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11. 发明授权

US07012770B2 Magnetic transfer apparatus and method for magnetic recording medium 失效
标题翻译：用于磁记录介质的磁转移装置和方法
公开(公告)号：US07012770B2
公开(公告)日：2006-03-14
申请号：US10658690
申请日：2003-09-09
申请人： Hiroyuki Yoshimura , Kiminori Sato
发明人： Hiroyuki Yoshimura , Kiminori Sato
IPC分类号： G11B5/86
CPC分类号： G11B5/865
摘要： A magnetic pattern of a master disc is transferred to both sides of a magnetic recording medium with no displacement. The origin of a magnetic recording medium can be determined by observing the inner or outer periphery of the magnetic recording medium. Back-side alignment marks are formed on the front side of the magnetic recording medium based on the origin thus determined. The back-side alignment marks can be observed with a microscope and front-side alignment marks for the magnetic recording medium can be provided on the back side of the magnetic recording medium. The alignment marks provided on the front/back sides of the magnetic recording medium are aligned with the corresponding alignment marks provided on the master disc, and a magnetic pattern formed on the soft magnetic material of the master disc is can be transferred to the magnetic recording medium.
摘要翻译：母盘的磁性图案被转移到没有位移的磁记录介质的两侧。可以通过观察磁记录介质的内周或外周来确定磁记录介质的原点。基于这样确定的原点，在磁记录介质的前侧形成背面对准标记。可以用显微镜观察背面对准标记，并且可以在磁记录介质的背面设置用于磁记录介质的前侧对准标记。设置在磁记录介质的前/后侧的对准标记与设置在母盘上的对应对准标记对准，并且形成在母盘的软磁性材料上的磁图案可以被传送到磁记录中。

12. 发明授权

US07001864B2 Catalyst composition for production of a polyurethane resin, and method for producing a polyurethane resin 失效
标题翻译：用于生产聚氨酯树脂的催化剂组合物，以及聚氨酯树脂的制造方法
公开(公告)号：US07001864B2
公开(公告)日：2006-02-21
申请号：US10802029
申请日：2004-03-17
申请人： Hiroyuki Kiso , Hiroyuki Yoshimura , Shinichi Inoue , Kouhei Tomita
发明人： Hiroyuki Kiso , Hiroyuki Yoshimura , Shinichi Inoue , Kouhei Tomita
IPC分类号： B01J31/00
CPC分类号： C08G18/1808 , C08G18/095 , C08G18/222
摘要： A catalyst composition for production of a polyurethane resin, which comprises a metal complex catalyst represented by the following formula (1): M(acac)n (1) wherein M represents Mn, Fe, Co, Ni, Cu, Zn, Zr, Ti, Hf, Al or Th, acac represents acetylacetonate, and n is an integer of from 1 to 4, and at least one compound selected from the group consisting of a bicyclic tertiary amine compound represented by the following formula (2): wherein n is an integer of from 1 to 3, a compound having a cumulative double bond, and a quaternary ammonium salt compound.
摘要翻译：一种用于生产聚氨酯树脂的催化剂组合物，其包含由下式表示的金属络合物催化剂

13. 发明申请

US20050069634A1 Method for manufacturing master disk for magnetic transfer 审中-公开
标题翻译：制造用于磁转移的主磁盘的方法
公开(公告)号：US20050069634A1
公开(公告)日：2005-03-31
申请号：US10900401
申请日：2004-07-28
申请人： Hiroyuki Yoshimura
发明人： Hiroyuki Yoshimura
IPC分类号： G11B21/10 , G11B5/82 , G11B5/84 , G11B5/851 , G11B5/858 , G11B5/86 , B05D5/12
CPC分类号： B82Y10/00 , G11B5/743 , G11B5/82 , G11B5/8404 , G11B5/865
摘要： A method for manufacturing a master disk for magnetic transfer, with which a soft magnetic material can be evenly embedded in the grooves of a master disk. A patterned groove is formed on the main surface of a silicon substrate, which is the substrate of a magnetic transfer master disk. A conductive thin film is formed on the main surface of the silicon substrate and the groove surfaces. With this conductive thin film as one electrode, a plating film of a soft magnetic material is deposited on the main surface of the silicon substrate and inside the grooves, on the bottom and sidewalls thereof, by electroplating. Then, just the soft magnetic material deposited on the main surface of the silicon substrate is removed by CMP, causing the soft magnetic material in the interior of the grooves to remain.
摘要翻译：一种用于制造用于磁转移的母盘的方法，通过该方法可以将软磁材料均匀地嵌入母盘的凹槽中。在作为磁转移母盘的基板的硅衬底的主表面上形成图案化的槽。在硅衬底的主表面和沟槽表面上形成导电薄膜。利用该导电性薄膜作为一个电极，通过电镀将软磁性材料的镀膜沉积在硅衬底的主表面上以及凹槽的内侧，底部和侧壁上。然后，仅通过CMP去除沉积在硅衬底的主表面上的软磁材料，使得凹槽内部的软磁材料残留。

14. 发明授权

US06780886B2 Antioxidant containing vitamin E metabolite 有权
标题翻译：含维生素E代谢物的抗氧化剂
公开(公告)号：US06780886B2
公开(公告)日：2004-08-24
申请号：US09963365
申请日：2001-09-27
申请人： Kazuo Kondo , Osamu Igarashi , Chikako Kiyose , Hiroyuki Yoshimura , Shigehiro Yoshitake
发明人： Kazuo Kondo , Osamu Igarashi , Chikako Kiyose , Hiroyuki Yoshimura , Shigehiro Yoshitake
IPC分类号： A61K31352
CPC分类号： A61K31/355 , A61K31/353 , Y10S514/824
摘要： The present invention provides a method of preventing or treating a disease caused by oxidation in vivo by administering a pharmacologically effective amount of at least one compound selected from the group consisting of: (1) 2,5,7,8-tetramethyl-2-(&bgr;-carboxyethyl)-6-hydroxychromane; and (2) 2,7, 8-trimethyl-2-(&bgr;-carboxyethyl)-6-hydroxychromane. Further, it provides use of a compound selected from the group consisting of (3) &agr;-tocopherol, (4) &agr;-tocotrienol, (5) &ggr;-tocopherol and (6) &ggr;-tocotrienol for generation in vivo of any of the above compounds (1) and (2) to treat a disease caused by oxidated low density lipoprotein (LDL).
摘要翻译：本发明提供一种通过施用药理学有效量的至少一种选自下组的化合物来预防或治疗由体内氧化引起的疾病的方法：（1）2,5,7,8-四甲基-2- （β-羧乙基）-6-羟基苯并二氢吡喃; 和（2）2,7,8-三甲基-2-（β-羧乙基）-6-羟基苯并二氢吡喃。此外，其提供了使用选自（3）α-生育酚，（4）α-生育三烯酚，（5）γ-生育酚和（6）γ-生育三烯酚的化合物，用于在上述任一种中产生化合物（1）和（2）治疗由氧化低密度脂蛋白（LDL）引起的疾病。

15. 发明授权

US06336107B1 Method and system of automatic arrangement of composing elements 失效
标题翻译：组合元素自动排列的方法和系统
公开(公告)号：US06336107B1
公开(公告)日：2002-01-01
申请号：US09124890
申请日：1998-07-30
申请人： Tomohiro Uchida , Natsuki Oka , Hiroyuki Yoshimura
发明人： Tomohiro Uchida , Natsuki Oka , Hiroyuki Yoshimura
IPC分类号： G06N304
CPC分类号： G06F17/5072
摘要： past positions of a plurality of composing elements indicated by various past arrangement examples are given to each potential function corresponding to one composing element, and parameter values of the potential functions corresponding to the composing elements are automatically set on condition that a past total potential energy obtained by solving the potential functions is minimized. Thereafter, the parameter values are given to the potential functions in which a position of any composing element is not determined, and particular positions of the composing elements are determined on condition that a total potential energy obtained by solving the potential functions is minimized. Because each potential function corresponding to one composing element has an attraction term indicating the attraction between the composing element and the other composing elements and an attraction-repulsion term indicating the setting of the composing element at a position spaced at moderate distances from the other composing elements, the particular positions of the composing elements are set in an optimum arrangement. Accordingly, the optimum arrangement of the composing elements can be automatically obtained without extracting any arrangement knowledge from a skilled person.
摘要翻译：对于与一个构成要素相对应的各个电位函数，赋予由各种过去的配置例子指示的多个组成元素的过去位置，并且在获得的过去总势能的条件下自动设置与组成元素相对应的潜在函数的参数值通过解决潜在的功能最小化。此后，将参数值赋予未确定任何组成元素的位置的潜在功能，并且在通过求解潜在功能获得的总势能最小化的条件下确定组成元件的特定位置。由于与一个构成要素对应的每个潜在功能具有表示构成要素与其他构成要素之间的吸引力的吸引项，还具有表示构成要素在与其他构成要素间隔中距离的位置的设定的吸引力排斥项，组合元件的特定位置被设定为最佳布置。因此，可以自动获得组合元件的最佳布置，而不需要从技术人员那里提取任何安排知识。

16. 发明授权

US6121309A Fused-ring carboxylic acid derivatives 失效
标题翻译：稠环羧酸衍生物
公开(公告)号：US6121309A
公开(公告)日：2000-09-19
申请号：US125522
申请日：1998-08-20
申请人： Katsuya Tagami , Hiroyuki Yoshimura , Mitsuo Nagai , Shigeki Hibi , Kouichi Kikuchi , Takashi Sato , Makoto Okita , Yasushi Okamoto , Yumiko Nagasaka , Naoki Kobayashi , Takayuki Hida , Kenji Tai , Naoki Tokuhara , Seiichi Kobayashi
发明人： Katsuya Tagami , Hiroyuki Yoshimura , Mitsuo Nagai , Shigeki Hibi , Kouichi Kikuchi , Takashi Sato , Makoto Okita , Yasushi Okamoto , Yumiko Nagasaka , Naoki Kobayashi , Takayuki Hida , Kenji Tai , Naoki Tokuhara , Seiichi Kobayashi
IPC分类号： C07C69/76 , C07C69/94 , C07D207/32 , C07D207/337 , C07D307/54 , C07D333/24 , C07D405/04 , C07D405/10 , C07D405/14 , C07D407/04 , C07D409/04 , C07D409/10 , C07D409/14 , A61K31/40 , C07D405/00
CPC分类号： C07D207/337 , C07C69/76 , C07C69/94 , C07D307/54 , C07D333/24 , C07D405/04 , C07D405/10 , C07D405/14 , C07D407/04 , C07D409/04 , C07D409/10 , C07D409/14
摘要： The present invention provides a medicament exhibiting excellent retinoic acid receptor agonism.A Carboxylic acid derivative having a fused ring which is represented by the following formula or a pharmacologically acceptable salt thereof: ##STR1## {wherein the symbol ----- represents a single bond or a double bond; X, Y, Z, P, Q, U, V and W are each a group represented by the formula: --O-- or --S--, or a group represented by the formula: ##STR2## [wherein R.sup.k (k:1 to 8) is hydrogen, halogeno, optionally substituted lower alkyl or the like, with either of R.sup.7 and R.sup.8 being a group represented by the formula: ##STR3## (wherein A and B are each independently an optionally substituted aromatic hydrocarbon ring or an optionally substituted unsaturated heterocycle; and D is optionally protected carboxyl)]}.
摘要翻译： PCT No.PCT / JP97 / 00852 Sec。 371日期：1998年8月20日 102（e）1998年8月20日PCT PCT 1997年3月18日PCT公布。公开号WO97 / 34869 日期：1997年9月25日本发明提供了显示出优异的视黄酸受体激动作用的药物。具有由下式表示的稠环的羧酸衍生物或其药理学上可接受的盐：{其中符号+ E，uns ----- + EE表示单键或双键; X，Y，Z，P，Q，U，V和W分别是由下式表示的基团：-O-或-S-，或由下式表示的基团：[其中R k（k：1至8）是氢，卤素，任选取代的低级烷基等，其中R 7和R 8中的任一个是由下式表示的基团：（其中A和B各自独立地是任选取代的芳族烃环或任选取代的不饱和杂环; D 任选保护羧基）]}。

17. 发明授权

US5831178A Vibration type measuring instrument 失效
标题翻译：振动式测量仪
公开(公告)号：US5831178A
公开(公告)日：1998-11-03
申请号：US705343
申请日：1996-08-29
申请人： Hiroyuki Yoshimura , Takahiro Kudo , Masami Kishiro
发明人： Hiroyuki Yoshimura , Takahiro Kudo , Masami Kishiro
IPC分类号： G01N9/00 , G01F1/84
CPC分类号： G01F1/849 , G01F1/8418 , G01F1/8431 , G01F1/8436 , G01N9/002 , B29C2043/046 , B29K2105/251
摘要： A vibration type measuring instrument measures at least one of a mass flow rate and a density of a fluid flowing through a straight measurement pipe by vibrating the measurement pipe, obtains a frequency ratio of a resonant frequency of a first vibration mode to a resonant frequency of a second vibration mode of the measurement pipe, and corrects a measured value of at least one of the mass flow rate and the density according to the frequency ratio. The instrument includes a first vibration detector for detecting at least one of a vibration generated in the measurement pipe depending on the mass flow rate and the resonant frequency of the first vibration mode of the measurement pipe; and a second vibration detector for detecting the resonant frequency of the second vibration mode of the measurement pipe. The second vibration detector is provided around an antinode of the second vibration mode of the measurement pipe to improve the detection sensitivity in the second vibration mode.
摘要翻译：振动型测量仪器通过振动测量管来测量流过直线测量管的流体的质量流量和密度中的至少一个，获得第一振动模式的谐振频率与谐振频率的频率比测量管的第二振动模式，并且根据频率比来校正质量流率和密度中的至少一个的测量值。该仪器包括：第一振动检测器，用于根据质量流量和测量管的第一振动模式的共振频率来检测在测量管中产生的振动中的至少一个; 以及第二振动检测器，用于检测测量管的第二振动模式的共振频率。第二振动检测器围绕测量管的第二振动模式的波腹设置，以提高第二振动模式下的检测灵敏度。

18. 发明授权

US5612356A Heterocycle-containing carbonic acid derivatives 失效
标题翻译：含杂环的碳酸衍生物
公开(公告)号：US5612356A
公开(公告)日：1997-03-18
申请号：US295636
申请日：1995-04-25
申请人： Hiroyuki Yoshimura , Mitsuo Nagai , Shigeki Hibi , Koichi Kikuchi , Ieharu Hishinuma , Junichi Nagakawa , Makoto Asada , Norimasa Miyamoto , Takayuki Hida , Aichi Ogasawara , Isao Yamatsu
发明人： Hiroyuki Yoshimura , Mitsuo Nagai , Shigeki Hibi , Koichi Kikuchi , Ieharu Hishinuma , Junichi Nagakawa , Makoto Asada , Norimasa Miyamoto , Takayuki Hida , Aichi Ogasawara , Isao Yamatsu
IPC分类号： C07D335/08 , A61K31/34 , A61K31/343 , A61K31/38 , A61K31/381 , A61K31/382 , A61K31/40 , A61K31/403 , A61K31/415 , A61K31/4184 , A61K31/42 , A61K31/423 , A61K31/425 , A61K31/428 , A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/47 , A61K31/473 , A61P1/16 , A61P5/12 , A61P17/00 , A61P17/14 , A61P19/00 , A61P29/00 , A61P35/00 , A61P37/00 , A61P43/00 , C07C69/76 , C07C211/31 , C07D209/56 , C07D209/58 , C07D215/04 , C07D221/06 , C07D221/16 , C07D221/18 , C07D231/54 , C07D235/02 , C07D261/20 , C07D277/60 , C07D307/77 , C07D307/92 , C07D311/92 , C07D333/38 , C07D333/50 , C07D335/06 , C07D401/04 , C07D401/06 , C07D401/14 , C07D403/04 , C07D403/06 , C07D405/06 , C07D409/06 , C07D409/14 , C07D417/04 , C07D471/04 , C07D487/04 , C07D491/04 , C07D491/044 , C07D491/048 , C07D491/052 , C07D493/04 , C07D495/04 , C07D498/04 , C07D513/04
CPC分类号： C07D495/04 , C07D209/56 , C07D221/18 , C07D231/54 , C07D277/60 , C07D307/77 , C07D311/92 , C07D333/38 , C07D333/50 , C07D335/08 , C07D401/04 , C07D401/06 , C07D401/14 , C07D403/04 , C07D403/06 , C07D405/06 , C07D409/06 , C07D409/14 , C07D417/04 , C07D491/04
摘要： A heterocycle-containing carbonic acid derivative represented by the following general formula (I): ##STR1## or a physiologically acceptable salt thereof which exhibits an excellent preventive and therapeutic effect against various diseases, and an intermediate which is useful for the production of the heterocycle-containing carbonic acid derivative.
摘要翻译： PCT No.PCT / JP93 / 01841 Sec。 371日期1995年04月25日 102（e）日期1995年4月25日PCT提交1993年12月20日PCT公布。公开号WO94 / 14777 日期：1994年7月7日由以下通式（I）表示的含杂环的碳酸衍生物：对各种疾病具有优异的预防和治疗作用的中间体可用于制备含杂环的碳酸衍生物。

19. 发明授权

US5476863A Glycerin derivative and its pharmacological use 失效
标题翻译：甘油衍生物及其药理用途
公开(公告)号：US5476863A
公开(公告)日：1995-12-19
申请号：US129301
申请日：1993-09-30
申请人： Kazuo Okano , Osamu Asano , Naoyuki Shimomura , Tetsuya Kawahara , Shinya Abe , Shuhei Miyazawa , Mitsuaki Miyamoto , Hiroyuki Yoshimura , Koukichi Harada , Junsaku Nagaoka , Tsutomu Kawata , Tsutomu Yoshimura , Hiromasa Suzuki , Shigeru Souda , Yoshimasa Machida , Kouichi Katayama , Isao Yamatsu
发明人： Kazuo Okano , Osamu Asano , Naoyuki Shimomura , Tetsuya Kawahara , Shinya Abe , Shuhei Miyazawa , Mitsuaki Miyamoto , Hiroyuki Yoshimura , Koukichi Harada , Junsaku Nagaoka , Tsutomu Kawata , Tsutomu Yoshimura , Hiromasa Suzuki , Shigeru Souda , Yoshimasa Machida , Kouichi Katayama , Isao Yamatsu
IPC分类号： C07D213/40 , C07D401/06 , C07D401/12 , C07D405/12 , A61K31/44 , A61K31/495 , C07D213/72
CPC分类号： C07D213/40 , C07D401/06 , C07D401/12 , C07D405/12
摘要： A glycerin derivative having the following formula (I) or (I') and a pharmacologically acceptable salt thereof are useful to treat diseases caused by the platelet activating factor. ##STR1##
摘要翻译：具有下式（I）或（I'）的甘油衍生物及其药理学上可接受的盐可用于治疗血小板活化因子引起的疾病。（I）（I）

20. 发明授权

US5409909A 1,4-diazepine derivative and its pharmaceutical use 失效
标题翻译： 1,4-二氮杂衍生物及其药物用途
公开(公告)号：US5409909A
公开(公告)日：1995-04-25
申请号：US214850
申请日：1994-03-18
申请人： Kazuo Okano , Shuhei Miyazawa , Richard S. J. Clark , Shinya Abe , Tetsuya Kawahara , Naoyuki Kimomura , Osamu Asano , Hiroyuki Yoshimura , Mitsuaki Miyamoto , Yoshimori Sakuma , Kenzo Muramoto , Hiroshi Obaishi , Koukichi Harada , Hajime Tsunoda , Satoshi Katayama , Kouji Yamada , Shigeru Souda , Yoshimasa Machida , Kouichi Katayama , Isao Yamatsu
发明人： Kazuo Okano , Shuhei Miyazawa , Richard S. J. Clark , Shinya Abe , Tetsuya Kawahara , Naoyuki Kimomura , Osamu Asano , Hiroyuki Yoshimura , Mitsuaki Miyamoto , Yoshimori Sakuma , Kenzo Muramoto , Hiroshi Obaishi , Koukichi Harada , Hajime Tsunoda , Satoshi Katayama , Kouji Yamada , Shigeru Souda , Yoshimasa Machida , Kouichi Katayama , Isao Yamatsu
IPC分类号： C07D495/14 , C07D495/22 , A61K31/55
CPC分类号： C07D495/14
摘要： A triazolo-1,4-di-azepine compound of the below given formula and a pharmacologically acceptable salt thereof are disclosed and useful in the pharmaceutical field, especially to treat allergic diseases: ##STR1## in which R1 and R2 are hydrogen or an alkyl, R3 is hydrogen or a halogen, R4 is hydrogen or an alkyl, X is --OCO--, --NHCO--, --CO-- or others and Y is a cycloalkyl, a cycloalkylalkyl, an alkynyl or others.
摘要翻译：公开了以下给定式的三唑并-1,4-二氮杂化合物及其药理学上可接受的盐，其可用于药物领域，特别是治疗过敏性疾病：其中R 1和R 2为氢或烷基，R 3为氢或卤素，R 4为氢或烷基，X为-OCO - ， - NHCO - ， - CO-等，Y为环烷基，环烷基烷基，炔基等。

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