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11. 发明授权

US07931022B2 Method and apparatus for dispensing inhalator medicament 有权
标题翻译：用于分配吸入器药物的方法和装置
公开(公告)号：US07931022B2
公开(公告)日：2011-04-26
申请号：US10267013
申请日：2002-10-08
申请人： Keith A. Johnson , Robert A. Casper , David L. Gardner
发明人： Keith A. Johnson , Robert A. Casper , David L. Gardner
IPC分类号： A61M11/00
CPC分类号： B65D81/3261 , A61J1/035 , A61M15/0003 , A61M15/0045 , A61M15/0048 , A61M2202/064
摘要： An apparatus and method for delivering a plurality of medication includes providing first and second medicament on a medicament pack in separate containers for preventing either medicament from interfering with the stability of the other. In accordance with the method, the medicaments are preferably delivered in a single inhalation.
摘要翻译：用于递送多种药物的装置和方法包括在分离的容器中的药物包装上提供第一和第二药物，以防止药物干扰另一药物的稳定性。根据该方法，药物优选在单次吸入中递送。

12. 发明授权

US06658862B2 Cascaded thermoacoustic devices 失效
标题翻译：级联热声器件
公开(公告)号：US06658862B2
公开(公告)日：2003-12-09
申请号：US10125268
申请日：2002-04-18
申请人： Gregory W. Swift , Scott N. Backhaus , David L. Gardner
发明人： Gregory W. Swift , Scott N. Backhaus , David L. Gardner
IPC分类号： F25B900
CPC分类号： F02G1/0435 , F02G2243/54 , F25B9/145 , F25B2309/1402 , F25B2309/1407
摘要： A thermoacoustic device is formed with a resonator system defining at least one region of high specific acoustic impedance in an acoustic wave within the resonator system. A plurality of thermoacoustic units are cascaded together within the region of high specific acoustic impedance, where at least one of the thermoacoustic units is a regenerator unit.
摘要翻译：热声装置形成有谐振器系统，其在谐振器系统内的声波中限定至少一个具有高声阻抗的区域。多个热声单元在高声学阻抗的区域内级联在一起，其中至少一个热声单元是再生器单元。

13. 发明授权

US06644028B1 Method and apparatus for rapid stopping and starting of a thermoacoustic engine 失效
标题翻译：用于快速停止和启动热声发动机的方法和装置
公开(公告)号：US06644028B1
公开(公告)日：2003-11-11
申请号：US10176311
申请日：2002-06-20
申请人： Gregory W. Swift , Scott N. Backhaus , David L. Gardner
发明人： Gregory W. Swift , Scott N. Backhaus , David L. Gardner
IPC分类号： F01B2908
CPC分类号： F25B9/14 , F02G2243/54 , F25B9/145 , F25B2309/1403 , F25B2309/1424
摘要： A thermoacoustic engine-driven system with a hot heat exchanger, a regenerator or stack, and an ambient heat exchanger includes a side branch load for rapid stopping and starting, the side branch load being attached to a location in the thermoacoustic system having a nonzero oscillating pressure and comprising a valve, a flow resistor, and a tank connected in series. The system is rapidly stopped simply by opening the valve and rapidly started by closing the valve.
摘要翻译：具有热交换器，再生器或堆叠的热声发动机驱动系统和环境热交换器包括用于快速停止和起动的侧分支负载，该侧分支负载附接到具有非零振荡的热声系统中的位置压力并且包括串联连接的阀，流阻器和罐。系统通过打开阀门即可快速停止，并通过关闭阀门快速启动。

14. 发明授权

US06357442B1 Inhalation actuated device for use with metered dose inhalers (MDIS) 有权
标题翻译：用于计量吸入器（MDIS）的吸入驱动装置
公开(公告)号：US06357442B1
公开(公告)日：2002-03-19
申请号：US09181150
申请日：1998-10-27
申请人： Robert A. Casper , Frank A. Leith , David L. Gardner , John Medlin Snow , Zachary Wood Lyon
发明人： Robert A. Casper , Frank A. Leith , David L. Gardner , John Medlin Snow , Zachary Wood Lyon
IPC分类号： A61M1100
CPC分类号： A61M15/0091 , A61M15/0068 , A61M15/009 , A61M15/0095
摘要： A device for use with metered dose inhalers includes a housing configured with a void to receive a metered dose inhaler, an actuator assembly which is configured to selectively apply force to the metered dose inhaler to cause the metered dose inhaler to release medicament, and a cocking mechanism for placing the actuator assembly in an armed configuration. The device is configured to actuate the metered dose inhaler as the user inhales, thereby ensuring improved medicament delivery. Additionally, the device is configured to prevent the metered dose inhaler from remaining in a vented position.
摘要翻译：与计量剂量吸入器一起使用的装置包括构造成具有接收计量剂量吸入器的空隙的壳体，构造成选择性地将力施加到计量剂量吸入器以引起计量剂量吸入器释放药物的致动器组件，以及起搏器用于将致动器组件放置在武装配置中的机构。该装置被配置成当用户吸入时致动计量剂量吸入器，从而确保改进的药物输送。此外，该装置被配置为防止计量剂量吸入器保持在排气位置。

15. 发明授权

US5988163A Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of delivery of medicament 失效
标题翻译：干粉药物吸入器具有用于触发药物递送的吸入激活的流动分流装置
公开(公告)号：US5988163A
公开(公告)日：1999-11-23
申请号：US76255
申请日：1998-05-11
申请人： Robert A. Casper , Frank A. Leith , David L. Gardner
发明人： Robert A. Casper , Frank A. Leith , David L. Gardner
IPC分类号： A61M15/00
CPC分类号： A61M15/0065 , A61M15/0028 , A61M15/003 , A61M15/0033 , A61M15/0091 , A61M2202/064
摘要： An inhalation-activated inhalator having a primary inhalation passage and a secondary inhalation passage disposed in communication with the primary inhalation passage and a source of medicament. The primary inhalation passage has a flow inhibiting mechanism connected to a blocking plate positioned to selectively block fluid flow between the secondary and primary inhalation passage. As the user's inhalation reaches a defined rate, the flow inhibiting mechanism restricts flow through the primary inhalation passage and moves the blocking plate to enable airflow through the secondary passage. Thus, as the user achieves a desired inhalation rate, the medicament is provided through the secondary inhalation passage, thereby optimizing the delivery of medicament to the lungs.
摘要翻译：具有主要吸入通道和与主要吸入通道连通的辅助吸入通道和药物源的吸入激活吸入器。主吸入通道具有连接到阻挡板的流动抑制机构，该阻塞板定位成选择性地阻挡次级和主要吸入通道之间的流体流动。当用户的吸入达到限定的速度时，流动抑制机构限制通过主要吸入通道的流动并移动阻挡板以使气流能够通过次级通道。因此，当使用者达到期望的吸入速率时，通过二次吸入通道提供药物，从而优化药物向肺的递送。

16. 发明授权

US4777648A Line tilt compensation method and apparatus 失效
标题翻译：线倾斜补偿方法和装置
公开(公告)号：US4777648A
公开(公告)日：1988-10-11
申请号：US941680
申请日：1986-12-15
申请人： David L. Gardner
发明人： David L. Gardner
IPC分类号： H04N7/169 , H04K1/02
CPC分类号： H04N7/1696
摘要： An improved technique for removing line tilt and other types of line rate correlated noise interjected into the active portions of a video signal during transmission and reception of the video signal. The improved technique involves measuring the amplitude of the line rate correlated noise in a received video signal at points sampled across the active portions of a plurality of lines in the video signal. The video lines used for measurement are preferably constant-amplitude dummy video lines inserted into the video signal at the bottom of each video field prior to transmission of the video signal. A complementary line-rate-correlated noise waveform, based on the amplitude measurements, is then generated and summed with the active portions of the received video signal to remove the line rate correlated noise from the video signal.
摘要翻译：一种用于在视频信号的发送和接收期间去除视频信号的有效部分中的线倾斜和其他类型的线速相关噪声的改进技术。改进的技术包括测量在视频信号中的多个行的有效部分上采样的点处的接收视频信号中的线速度相关噪声的幅度。用于测量的视频线优选是在发送视频信号之前插入到每个视频场的底部的视频信号中的恒定幅度虚拟视频行。然后基于幅度测量产生互补的线速率相关噪声波形，并将其与接收到的视频信号的有效部分相加，以从视频信号中去除线路速率相关噪声。

17. 发明授权

US4333783A Pipe coating apparatus 失效
标题翻译：管涂装置
公开(公告)号：US4333783A
公开(公告)日：1982-06-08
申请号：US180379
申请日：1980-08-22
申请人： David L. Gardner
发明人： David L. Gardner
IPC分类号： B28B19/00 , B65H81/08 , B65H81/00
CPC分类号： B28B19/0038 , B65H81/08
摘要： Pipe coating apparatus is disclosed. In the preferred and illustrated embodiment, a laterally deployed conveyor belt rotating around a pair of rollers passes beneath the pipe to be coated. Coating material is supplied into a hopper above the belt. The hopper includes positioned slots for receiving reinforcing mesh therein and locates the reinforcing mesh in an extruded ribbon of coating material supported by the conveyor belt and applied to the pipe in helical turns. The application of multiple turns of reinforcing mesh plus shaping of the extruded ribbon enables a thicker layer of coating material to be applied to the pipe, and it is reinforced with multiple layers of reinforcing mesh wire.
摘要翻译：公开了管涂装置。在优选和示出的实施例中，围绕一对辊旋转的横向布置的传送带在待涂覆的管的下方通过。涂料被送入皮带上方的料斗中。料斗包括用于在其中接收加强网的定位槽，并将加强网定位在由输送带支撑的挤出的涂层带中，并以螺旋形的方式施加到管。施加多圈加强网加上挤压带的成型使得能够将更厚的涂层材料施加到管道上，并且通过多层增强网状网加强。

18. 发明授权

US07051734B2 Medicament respiratory delivery device and method 有权
公开(公告)号：US07051734B2
公开(公告)日：2006-05-30
申请号：US10685187
申请日：2003-10-14
申请人： Robert A. Casper , John M. Snow , David L. Gardner , Vincent J. Sullivan , Anjana Bhuta Wills , Lawrence A. Monahan , Christopher J. Knors
发明人： Robert A. Casper , John M. Snow , David L. Gardner , Vincent J. Sullivan , Anjana Bhuta Wills , Lawrence A. Monahan , Christopher J. Knors
IPC分类号： A61M15/00 , A61M16/00 , A61M15/08
CPC分类号： B05B11/061 , A61M11/02 , A61M15/0028 , A61M15/0031 , A61M15/0081 , A61M15/08 , A61M2202/04 , A61M2202/064 , A61M2205/073 , B05B11/062
摘要： A medicament respiratory delivery device including a housing having a chamber including coaxially aligned inlet and outlet, a medicament cartridge located within the chamber having a passage therethrough and membranes sealing the passage having a burst pressure of less than 10 atmospheres, a manually actuatable fluid delivery device having an outlet in fluid communication with the chamber and a manually actuated valve located between the outlet of the fluid delivery device and the chamber inlet for delivery of fluid under pressure to the valve. The medicament respiratory delivery device of this invention may be utilized to deliver a controlled unit dose of an aerosolizable medicament on demand by first pressurizing a pressure chamber in the pressure delivery device upstream of the valve, then opening the valve to open the membranes and express the medicament through the chamber outlet.

19. 发明授权

US06561186B2 Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament 有权
公开(公告)号：US06561186B2
公开(公告)日：2003-05-13
申请号：US09995923
申请日：2001-11-27
申请人： Robert A. Casper , Frank A. Leith , David L. Gardner , John M. Snow , Zachary W. Lyon , David S. Farrar
发明人： Robert A. Casper , Frank A. Leith , David L. Gardner , John M. Snow , Zachary W. Lyon , David S. Farrar
IPC分类号： A61M1500
CPC分类号： A61M15/0028 , A61M11/001 , A61M11/002 , A61M15/003 , A61M15/0033 , A61M15/0065 , A61M15/0091 , A61M15/0093 , A61M2202/064
摘要： An inhalation-activated inhalator having a primary inhalation passage and a secondary inhalation passage disposed in communication with the primary inhalation passage and a source of medicament. The primary inhalation passage has airflow inhibiting mechanism connected to a blocking plate positioned to selectively block fluid flow in the secondary inhalation passage. As the user's inhalation reaches a defined rate, the flow inhibiting mechanism restricts flow through the primary inhalation passage and moves the blocking plate to enable airflow through the secondary passage. Thus, as the user achieves a desired inhalation rate, the medicament is provided through the secondary inhalation passage, thereby optimizing the delivery of medicament to the lungs.

20. 发明授权

US06550477B1 Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament 有权
公开(公告)号：US06550477B1
公开(公告)日：2003-04-22
申请号：US09492714
申请日：2000-01-27
申请人： Robert A. Casper , Frank A. Leith , David L. Gardner , John M. Snow , Zachary W. Lyon , David S. Farrar
发明人： Robert A. Casper , Frank A. Leith , David L. Gardner , John M. Snow , Zachary W. Lyon , David S. Farrar
IPC分类号： A61M1600
CPC分类号： A61M15/0028 , A61M11/001 , A61M11/002 , A61M15/003 , A61M15/0033 , A61M15/0065 , A61M15/0091 , A61M15/0093 , A61M2202/064
摘要： An inhalation-activated inhalator having a primary inhalation passage and a secondary inhalation passage disposed in communication with the primary inhalation passage and a source of medicament. The primary inhalation passage has airflow inhibiting mechanism connected to a blocking plate positioned to selectively block fluid flow in the secondary inhalation passage. As the user's inhalation reaches a defined rate, the flow inhibiting mechanism restricts flow through the primary inhalation passage and moves the blocking plate to enable airflow through the secondary passage. Thus, as the user achieves a desired inhalation rate, the medicament is provided through the secondary inhalation passage, thereby optimizing the delivery of medicament to the lungs.

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