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11. 发明专利

DE69622167T2 未知
公开(公告)号：DE69622167T2
公开(公告)日：2002-11-14
申请号：DE69622167
申请日：1996-04-09
申请人： ELECTRO PETROLEUM , LEHIGH UNIVERSITY BETHLEHEM
发明人： WITTLE KENNETH , PAMUKCU SIBEL
IPC分类号： G21F9/28 , B01D35/06 , B01D57/02 , B01D61/56 , B03C5/00 , B09B3/00 , B09C1/02 , B09C1/08 , C02F1/46 , C02F1/469 , C25C7/00 , G21F9/06 , G21F9/30 , C25C1/00
摘要： An electrokinetic system and method are provided for removing charged species from a sample in which said charged species is commingled with at least one radionuclide. The apparatus comprises an anode compartment comprising an anode, a cathode compartment comprising a cathode, and a treatment zone in fluid communication with the anode and cathode compartments for containing the sample. The anode compartment, cathode compartment, and treatment zone are arranged so that a voltage gradient applied between the anode and the cathode induces an electrical current flow through the sample in the treatment zone. The current causes migration of the positively charged species in the sample toward the cathode and the negatively charges species toward the anode. A pH controller is provided for monitoring and adjusting acidity and basicity to facilitate the removal of salts while maintaining contaminants within the sample.

12. 发明申请

WO2023003993A1 LABEL-FREE CLASSIFICATION OF CELLS BY IMAGE ANALYSIS AND MACHINE LEARNING 审中-公开
公开(公告)号：WO2023003993A1
公开(公告)日：2023-01-26
申请号：PCT/US2022/037790
申请日：2022-07-21
申请人： CORIELL INSTITUTE FOR MEDICAL RESEARCH , LEHIGH UNIVERSITY
发明人： HUANG, Jian , LIU, Yaling
IPC分类号： G06T7/00 , G06N3/08 , G01N33/574 , G01N21/64
摘要： Technologies are disclosed for distinguishing among different types of cells. Techniques may include receiving a plurality of first images. The plurality of first images may depict first cells of a first type or a second type. Techniques may include, for each of the plurality of first images, receiving an indicator identifying whether the first image depicts a first cell of the first type or the second type. Techniques may include inputting, into a deep-learning (DL) model, the plurality of first images and the indicator for each of the plurality of first images. Techniques may include inputting, into the DL model, a second image comprising a second cell of the first type or the second type. Techniques may include determining whether the second cell is of the first type or the second type based on the plurality of first images and the indicator for each of the plurality of first images.

13. 发明申请

WO2018209339A1 SPACE DIVISION MULTIPLEXING OPTICAL COHERENCE TOMOGRAPHY USING AN INTEGRATED PHOTONIC DEVICE 审中-公开
公开(公告)号：WO2018209339A1
公开(公告)日：2018-11-15
申请号：PCT/US2018/032529
申请日：2018-05-14
申请人： LEHIGH UNIVERSITY
发明人： ZHOU, Chao
IPC分类号： A61B3/00 , A61B3/10 , A61B5/00 , G01B9/00 , G01B9/02
摘要： Integrated photonic chips and related systems and methods suitable for space-division multiplexing optical coherence tomography scanning are disclosed. In one embodiment, the photonic chip comprises a substrate, an optical input port which receives an incident sampling beam from an external light source, a plurality of optical output ports configured to transmit a plurality of sampling beams from the chip to a sample to capture scanned images of the sample, and a plurality of interconnected and branched waveguide channels formed in the substrate. Waveguide channels in a splitter region divide the sampling beam into the plurality of sampling beams at the output ports. Terminal portions of the waveguide channels in a time delay region associated with each output port have different predetermined lengths to create an optical time delay between the sampling beams. In some embodiments, the chip further comprises an interferometer region to create interference patterns.

14. 发明申请

WO2016134062A1 CONTROLLING FRICTION CHARACTERISTICS OF RESILIENT MEMBERS USING NEAR-SURFACE MICROSTRUCTURES 审中-公开
标题翻译：使用表面微结构控制弹性构件的摩擦特性
公开(公告)号：WO2016134062A1
公开(公告)日：2016-08-25
申请号：PCT/US2016/018332
申请日：2016-02-17
申请人： LEHIGH UNIVERSITY , COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN , MICHELIN RECHERCHE ET TECHNIQUE S.A.
发明人： JAGOTA, Anand , BAI, Ying , HE, Zhenping , HUI, Chung-Yuen , LEVRARD, Benjamin
IPC分类号： B32B7/04 , B32B27/08 , B32B3/08 , B32B3/30
CPC分类号： B32B3/08 , B32B3/30 , B32B7/04 , B32B7/06 , B32B27/08 , B32B2274/00 , B32B2475/00 , C09J7/00 , C09J7/203 , C09J7/22 , C09J2201/626
摘要： Resilient members having near-surface architectures including microstructures for controlling friction are provided. A film-terminated array of fibrils having a sharp film/fibril juncture exhibits an unexpectedly large enhancement of adhesion, static friction and sliding friction. The enhancement is provided against rough indenters. A film-terminated array of elongated ridges and valleys unexpectedly exhibits low adhesion, and an unexpectedly large enhancement of sliding friction. The film-terminated ridge/valley design provides an anisotropic structure with direction-dependent frictional properties. The increase in sliding friction force varies as a function of interfibrillar spacing, and corresponds to a mode in which buckling of the terminal film occurs. The near surface architectures may be designed with varying scales and varying parameters to provide performance characteristics tailored to various applications. By way of example, the film-terminated ridge/valley array may be incorporated in motor vehicles tires to provide low rolling resistance and high sliding friction allow for high-performance braking during vehicle operation.
摘要翻译：提供具有近表面结构的弹性构件，包括用于控制摩擦的微结构。具有尖锐的薄膜/原纤维接合处的具有薄膜封端的原纤维阵列表现出意想不到的增强的附着力，静摩擦力和滑动摩擦力。改进是针对粗头压痕。细长的脊和谷的薄膜终端阵列意外地表现出低的粘附性，并且意外地大的滑动摩擦的增强。电影终止的山脊/山谷设计提供了具有方向依赖的摩擦特性的各向异性结构。滑动摩擦力的增加作为纤维间距的函数而变化，并且对应于终端膜的翘曲发生的模式。近表面结构可以设计成具有不同的尺度和变化的参数，以提供针对各种应用定制的性能特征。作为示例，膜端接的脊/谷阵列可以并入机动车辆轮胎中以提供低滚动阻力，并且高滑动摩擦允许在车辆操作期间的高性能制动。

15. 发明申请

WO2015069824A2 DIAGNOSTIC SYSTEM AND METHOD FOR BIOLOGICAL TISSUE ANALYSIS 审中-公开
标题翻译：诊断系统和生物组织分析方法
公开(公告)号：WO2015069824A2
公开(公告)日：2015-05-14
申请号：PCT/US2014/064218
申请日：2014-11-06
申请人： LEHIGH UNIVERSITY
发明人： HUANG, Xiaolei , WAN, Sunhua , ZHOU, Chao
IPC分类号： G06F17/30 , H04L12/58
CPC分类号： G06K9/628 , G06K9/00147 , G06K9/6271 , G06K9/629 , G06K2009/4666 , G06T7/0012 , G06T7/11 , G06T7/40 , G06T7/41 , G06T11/60 , G06T2207/10056 , G06T2207/10101 , G06T2207/20021 , G06T2207/20081 , G06T2207/30024 , G06T2207/30068 , G06T2207/30096
摘要： A computer diagnostic system and related method are disclosed for automatically classifying tissue types in an original tissue image captured by an imaging device based on texture analysis. The system receives and divides the tissue image into multiple smaller tissue block images. In one non-limiting embodiment, a combination of local binary pattern (LBP) and average local binary pattern (ALBP) extractions are performed on each tissue block. Other texture analysis methods may be used. The extractions generate a set of LBP and ALBP features for each block which are used to classify its tissue type. The classification results are visually displayed in a digitally enhanced map of the original tissue image. In one embodiment, a tissue type of interest is displayed in the original tissue image. In another or the same embodiment, the map displays each of the different tissue types present in the original tissue image.
摘要翻译：公开了一种计算机诊断系统和相关方法，用于基于纹理分析自动分类由成像装置捕获的原始组织图像中的组织类型。系统将组织图像接收并分割成多个较小的组织块图像。在一个非限制性实施例中，在每个组织块上执行局部二进制模式（LBP）和平均局部二进制模式（ALBP）提取的组合。可以使用其他纹理分析方法。提取物为每个块生成一组LBP和ALBP特征，用于对其组织类型进行分类。分类结果可视化地显示在原始组织图像的数字增强图中。在一个实施例中，在原始组织图像中显示感兴趣的组织类型。在另一个或相同的实施例中，地图显示存在于原始组织图像中的每种不同的组织类型。

16. 发明申请

WO2012024015A3 TERAHERTZ SOURCE 审中-公开
公开(公告)号：WO2012024015A3
公开(公告)日：2012-02-23
申请号：PCT/US2011/039690
申请日：2011-06-09
申请人： LEHIGH UNIVERSITY , ZHAO, Pu , RAGAM, Srinivasa, Rao , DING, Yujie, J.
发明人： ZHAO, Pu , RAGAM, Srinivasa, Rao , DING, Yujie, J.
IPC分类号： H01S1/00
摘要： An optical system includes a first gain medium configured to be excited by an energy source and in response generate a first optical signal having first and second wavelengths. A Q- switch is disposed adjacent to the first gain medium for generating a pulsed optical signal in response to receiving the first optical signal. A non-linear optical crystal is configured to output a second optical signal having a frequency based on difference frequency generation of the first and second wavelengths of the pulsed optical signal.

17. 发明申请

WO2009146133A2 HIGH-VOLTAGE IMPULSE AMPLIFIER 审中-公开
标题翻译：高压脉冲放大器
公开(公告)号：WO2009146133A2
公开(公告)日：2009-12-03
申请号：PCT/US2009/039483
申请日：2009-04-03
申请人： LEHIGH UNIVERSITY , HALDER, Subrata , JIN, Renfeng , HWANG, James, C.M.
发明人： HALDER, Subrata , JIN, Renfeng , HWANG, James, C.M.
IPC分类号： H03F3/343 , H03F1/22
CPC分类号： H03F3/3435 , H03F2200/408 , H03F2200/93 , H04B1/7174
摘要： A circuit includes a first transistor in a common-collector configuration and a heterojunction bipolar transistor (HBT) in a common-emitter configuration. The first transistor has a base coupled to an input node for receiving a pulsed signal. A collector of the first transistor is coupled to a first voltage source node. A base of the HBT is coupled to an emitter of the first transistor. A collector of the HBT is coupled to a second voltage source node configured to bias the HBT normally off. The HBT operating isothermally when the pulsed signal has a short-pulse width and a low duty cycle. The first transistor drives the HBT when the pulsed signal is received at the base of the first transistor to output an amplified pulsed signal at the collector of the HBT.
摘要翻译：电路包括共集电极配置的第一晶体管和共发射极配置中的异质结双极晶体管（HBT）。第一晶体管具有耦合到输入节点的基极，用于接收脉冲信号。第一晶体管的集电极耦合到第一电压源节点。 HBT的基极耦合到第一晶体管的发射极。 HBT的集电极耦合到被配置成正常关断HBT偏置的第二电压源节点。当脉冲信号具有短脉冲宽度和低占空比时，HBT同时工作。当在第一晶体管的基极处接收脉冲信号时，第一晶体管驱动HBT，以在HBT的集电极处输出放大的脉冲信号。

18. 发明申请

WO2005014492A1 A METHOD FOR TREATING CONTAMINATED WATER 审中-公开
标题翻译：一种处理污水的方法
公开(公告)号：WO2005014492A1
公开(公告)日：2005-02-17
申请号：PCT/US2004/025584
申请日：2004-08-06
申请人： LEHIGH UNIVERSITY , ZHANG, Wei-xian
发明人： ZHANG, Wei-xian
IPC分类号： C02F1/70
CPC分类号： B09C1/002 , B09C1/08 , C02F1/705 , C02F2101/36 , C02F2103/007 , C02F2103/06 , Y10S422/90
摘要： Zero valent iron particles (14) having enhanced surface area are used to treat contaminated groundwater in-situ or above ground. Hollow and/or porous zero valent iron particles (14) having a generally spherical shape and porous surface are produced using a sacrificial substrate (10) and thermal treatment.
摘要翻译：具有增强的表面积的零价铁颗粒（14）用于原位或地上处理受污染的地下水。使用牺牲基板（10）和热处理来制造具有大致球形和多孔表面的中空和/或多孔零价铁颗粒（14）。

19. 发明申请

WO1992015791A1 STRUCTURAL CONNECTOR APPROXIMATING A CONE OF ELLIPTICAL CROSS-SECTION 审中-公开
标题翻译：结构连接器近似椭圆曲线
公开(公告)号：WO1992015791A1
公开(公告)日：1992-09-17
申请号：PCT/US1992001500
申请日：1992-02-24
申请人： LEHIGH UNIVERSITY
发明人： LEHIGH UNIVERSITY , PERREIRA, Noel, Duke , VISCOMI, B. Vincent , FLEISCHMAN, Robert, B.
IPC分类号： F16B07/00
CPC分类号： E04B5/43 , E04B1/2403 , E04B2001/2409 , E04B2001/2415 , E04B2001/2448 , E04B2001/2457 , F16B2200/10 , F16B2200/30 , Y10T403/61 , Y10T403/63 , Y10T403/76
摘要： A structural connector used to interconnect at least a first and a second member which includes a cone-shaped male part having an approximately elliptical cross-section attached to the first member and a female part forming a correspondingly elliptical cone-shaped cavity attached to the second member and adapted to receive the male part, whereby upon receipt of the male part within the cavity of the female part the first and second members are interconnected.

20. 发明申请

WO1990008529A2 7-ALKOXYCOUMARINS, DIHYDROPSORALENS, AND BENZODIPYRANONES AS PHOTO-ACTIVATED THERAPEUTIC AGENTS AND INHIBITORS OF EPIDERMAL GROWTH FACTOR 审中-公开
标题翻译： 7-羟基喹啉酮，二氢吲哚酮和苯并噻唑酮作为光敏剂治疗剂和抗生素生长因子的抑制剂
公开(公告)号：WO1990008529A2
公开(公告)日：1990-08-09
申请号：PCT/US1990000704
申请日：1990-01-23
申请人： LEHIGH UNIVERSITY , UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW ...
发明人： LEHIGH UNIVERSITY , UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW ... , HEINDEL, Ned, Duane , SILLER, Michele, Carole , LASKIN, Jeffrey, Dean , GALLO, Michael, A.
IPC分类号： A61K0
CPC分类号： C07D493/04
摘要： A photochemotherapeutic compound of formula (I), wherein (i) n is zero, W is a (C1-16) alkyl, alkenyl, or alkynyl linear or branched chain hydrocarbon, having no more than four O, N, or S atoms in or attached to the chain; or (ii) n is 1, W is CR2, and R, R', and R'' are independently H or CH3; or (iii) n is 2, W is CR2, and R, R', and R'' are independently H or CH3; and A, B, C, and D are independently selected from hydrogen, alkyl, aryl, halogen, amino, aminoalkyl, nitro, alkoxy, aryloxy, hydroxy, carboxy, haloalkyl, or haloalkoxy.
摘要翻译：式（I）的光化学治疗化合物，其中（i）n为0，W为（C1-16）烷基，烯基或炔基线性或支链烃，其中不超过四个O，N或S原子或连接到链上; 或（ii）n为1，W为CR 2，R，R'和R“独立地为H或CH 3; 或（iii）n为2，W为CR 2，R，R'和R“独立地为H或CH 3; A，B，C和D独立地选自氢，烷基，芳基，卤素，氨基，氨基烷基，硝基，烷氧基，芳氧基，羟基，羧基，卤代烷基或卤代烷氧基。

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