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11. 发明申请

WO2008150330A1 DEVICE AND ASSEMBLY FOR POSITIONING, STABILIZING AND TREATING AN EYE 审中-公开
标题翻译：用于定位，稳定和治疗眼睛的装置和装置
公开(公告)号：WO2008150330A1
公开(公告)日：2008-12-11
申请号：PCT/US2008/004999
申请日：2008-04-17
申请人： ORAYA THERAPEUTICS, INC. , GERTNER, Michael , ARNOLDUSSEN, Mark , HERRON, Matt
发明人： GERTNER, Michael , ARNOLDUSSEN, Mark , HERRON, Matt
IPC分类号： A61B3/00
CPC分类号： A61F9/008 , A61B3/113 , A61B3/12 , A61B3/152 , A61B17/0231 , A61F9/00804 , A61F9/00808 , A61F9/009 , A61F2009/00846 , A61F2009/00865 , A61N5/1017 , A61N5/1049 , A61N2005/1059 , A61N2005/1091
摘要： An eye contact device and assembly for stabilizing a human eye at a selected position in an external coordinate system is disclosed. The device includes an eye-contact member having an inner contact surface for contacting a front surface of an eye, and a vacuum port formed within the eye-contact member and communicating with the eye-contact member's contact surfaces, by which a negative pressure can be applied between the eye and the contact surface, to stabilize the position of the eye with respect to the device. The device, which is adapted to be biased against the patient's eye, to secure the device to the eye, may be pivotally coupled to a positioning arm, and may carry one or more beam-directing elements by which the position of the device in an external coordinate system can be determined.
摘要翻译：公开了一种用于在外部坐标系中的选定位置处稳定人眼的眼睛接触装置和组件。该装置包括具有用于接触眼睛前表面的内接触表面的眼睛接触构件和形成在眼睛接触构件内并与眼睛接触构件的接触表面连通的真空端口，负压可以施加在眼睛和接触表面之间，以稳定眼睛相对于装置的位置。适于被偏压抵靠患者眼睛的装置将装置固定到眼睛上的装置可以枢转地联接到定位臂，并且可以承载一个或多个光束引导元件，通过该元件将装置的位置可以确定外部坐标系。

12. 发明申请

WO2006055052A2 METHODS AND DEVICES FOR CHRONIC EMBOLIC PROTECTION 审中-公开
标题翻译：用于慢性栓塞保护的方法和装置
公开(公告)号：WO2006055052A2
公开(公告)日：2006-05-26
申请号：PCT/US2005/025021
申请日：2005-07-14
申请人： GERTNER, Michael
发明人： GERTNER, Michael
IPC分类号： A61M29/00
CPC分类号： A61F2/01 , A61F2002/018 , A61F2230/0019 , A61F2230/0069 , A61F2250/0023
摘要： A medical device for interposition between a first flow path and at least one second flow path is provided. The device includes a first surface facing toward the opening of at least one second flow path; and a second surface facing away from the opening of at least one second flow path. When the device is in the operative position, it extends less than the complete circumference of the first flow path and substantially covers the opening of at least one second flow path. The device contains one or more surface features to facilitate chronic implantation. The device further has one or more characteristic porosities. Different configurations are indicated depending on the pathophysiology being treated and dictate the characteristic porosity of the device. In some, cases blood is prevented from reaching the second flow path and in other cases, particulates traveling within the blood are prevented from reaching the second flow path. Methods of preventing emboli or blood flow into the second flow path are also provided. Methods and devices for delivery are also provided.
摘要翻译：提供了用于插入第一流路和至少一个第二流路之间的医疗装置。该装置包括面向至少一个第二流动路径的开口的第一表面; 以及远离至少一个第二流动路径的开口的第二表面。当设备处于操作位置时，其延伸小于第一流动路径的整个圆周并且基本上覆盖至少一个第二流动路径的开口。该装置包含一个或多个表面特征以便于慢性植入。该装置还具有一个或多个特征孔隙率。根据正在治疗的病理生理学来指示不同的构型，并且决定了器械的特征孔隙度。在一些情况下，防止血液到达第二流动路径，并且在其他情况下，防止在血液内行进的微粒到达第二流动路径。还提供了防止栓塞或血液流入第二流路的方法。还提供了交付方法和设备。

13. 发明申请

WO2005094447A2 DEVICES AND METHODS TO TREAT A PATIENT 审中-公开
标题翻译：用于治疗患者的装置和方法
公开(公告)号：WO2005094447A2
公开(公告)日：2005-10-13
申请号：PCT/US2005/009322
申请日：2005-03-19
申请人： MINIMUS SURGICAL SYSTEMS, INC. , GERTNER, Michael , BROMMER, Robert , SHEEHAN, Neil
发明人： GERTNER, Michael , BROMMER, Robert , SHEEHAN, Neil
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/08 , A61B17/28 , A61F5/00
CPC分类号： A61B17/0401 , A61B17/00234 , A61B17/0469 , A61B17/0487 , A61B17/29 , A61B2017/00398 , A61B2017/00827 , A61B2017/00871 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0445 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0464 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61F5/0076 , A61F5/0086
摘要： Disclosed are methods and apparatus for implantation into the walls or an organ such as the stomach. Deformable or inflatable anchors with a connector between are used to pull the walls of the organ together, or to implant devices in the wall of the organ. Also disclosed are surgical instruments useful in practicing the disclosed methods.
摘要翻译：公开了用于植入壁或诸如胃的器官的方法和装置。具有连接器的可变形或可充气的锚固件用于将器官的壁拉到一起，或者将器械植入器官壁。还公开了可用于实践所公开的方法的外科器械。

14. 发明申请

WO2004066806A2 AEROSOL DEVICE TO DELIVER BIOACTIVE AGENT 审中-公开
标题翻译：航空设备提供生物活性剂
公开(公告)号：WO2004066806A2
公开(公告)日：2004-08-12
申请号：PCT/US2003/028773
申请日：2003-09-11
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , GERTNER, Michael, E.
发明人： GERTNER, Michael, E.
IPC分类号： A61B
CPC分类号： A61M35/003 , A61B17/00491 , A61B2017/00522 , A61B2017/00889 , A61B2017/00893 , A61M11/06 , A61M13/00 , A61M15/0066 , A61M2202/0468 , A61M2202/064 , A61M2205/8225 , A61M2209/06 , B05B7/2424 , B05B7/2443 , A61M2202/0007
摘要： This invention provides surgical devices and methods to apply bioactive agents to surgical sites. The devices include, e.g., a body for attachment of a pressurized fluid vessel and a reservoir of bioactive agent for controlled spraying of an aerosol of bioactive agent for controlled spraying of an aerosol of bioactive agent.
摘要翻译：本发明提供了将生物活性剂施用于外科手术部位的手术装置和方法。这些装置包括例如用于附加加压流体容器的主体和用于受控喷雾生物活性剂气雾剂以控制喷雾生物活性剂气雾剂的生物活性剂储存器。

15. 发明申请

WO2011046880A3 ENERGETIC MODULATION OF NERVES 审中-公开
标题翻译：神经的能量调节
公开(公告)号：WO2011046880A3
公开(公告)日：2011-08-25
申请号：PCT/US2010052197
申请日：2010-10-11
申请人： GERTNER MICHAEL , KONA MEDICAL INC
发明人： GERTNER MICHAEL
IPC分类号： A61N1/18
CPC分类号： A61N2/006 , A61B5/0225 , A61B5/055 , A61B5/4035 , A61B5/4041 , A61B5/4047 , A61B5/4052 , A61B5/412 , A61B5/4528 , A61B5/4839 , A61B5/489 , A61B5/4893 , A61B6/03 , A61B6/032 , A61B6/037 , A61B6/506 , A61B8/00 , A61B8/06 , A61B8/08 , A61B8/4245 , A61B8/485 , A61B17/320068 , A61B18/14 , A61B18/18 , A61B90/37 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2090/374 , A61B2090/3762 , A61B2090/378 , A61N1/0551 , A61N5/00 , A61N5/0601 , A61N5/062 , A61N5/0622 , A61N7/00 , A61N7/02 , A61N2005/063 , A61N2007/0026 , A61N2007/003 , A61N2007/0078
摘要： In some examples, nerves surrounding arteries or leading to organs are targeted with energy sources to correct or modulate physiologic processes. In some examples, different types of energy sources are utilized singly or combined with one another. In some examples, bioactive agents or devices activated by the energy sources are delivered to the region of interest and the energy is enhanced by such agents or the agents are enhanced by the energy sources.
摘要翻译：在一些例子中，动脉周围或导致器官的神经以能量来源为目标以校正或调节生理过程。在一些示例中，不同类型的能量源单独使用或相互组合使用。在一些实例中，由能量源激活的生物活性剂或装置被递送到感兴趣的区域，并且通过这些试剂增强能量或者通过能量源增强试剂。

16. 发明申请

WO2008124801A3 ORTHOVOLTAGE RADIOSURGERY 审中-公开
公开(公告)号：WO2008124801A3
公开(公告)日：2008-12-31
申请号：PCT/US2008059808
申请日：2008-04-09
申请人： ORAYA THERAPEUTICS INC , GERTNER MICHAEL , HANSEN STEVEN D
发明人： GERTNER MICHAEL , HANSEN STEVEN D
IPC分类号： A61N5/10
CPC分类号： A61N5/1067 , A61B6/506 , A61B6/508 , A61N5/10 , A61N5/1001 , A61N5/1017 , A61N5/1045 , A61N5/1048 , A61N5/1049 , A61N5/1064 , A61N5/1065 , A61N5/1077 , A61N5/1084 , A61N2005/1019 , A61N2005/1022 , A61N2005/105 , A61N2005/1051 , A61N2005/1059 , A61N2005/1091 , A61N2005/1097
摘要： A radiosurgery system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, other disorders or tissues of a body are treated with the dose of radiation. In some embodiments, the target tissues are placed in a global coordinate system based on ocular imaging. In some embodiments, the target tissues inside the global coordinate system lead to direction of an automated positioning system that is directed based on the target tissues within the coordinate system. In some embodiments, a treatment plan is utilized in which beam energy and direction and duration of time for treatment is determined for a specific disease to be treated and/or structures to be avoided. In some embodiments, a fiducial marker is used to identify the location of the target tissues. In some embodiments, an eye is held with force and in alignment with the system. In some embodiments, the device automatically turns off with excessive movement outside of alignment along an axis of the eye. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.
摘要翻译：描述了放射外科系统，其被配置为将治疗剂量的辐射递送到患者中的目标结构。在一些实施方案中，治疗炎症性眼部疾病，特别是黄斑变性。在一些实施方案中，身体的其它病症或组织用辐射剂量治疗。在一些实施例中，目标组织基于眼睛成像被放置在全局坐标系中。在一些实施例中，全局坐标系统内的目标组织导致基于坐标系统内的目标组织定向的自动定位系统的方向。在一些实施例中，使用治疗计划，其中针对要治疗的特定疾病和/或要避免的结构确定束能量和治疗时间的方向和持续时间。在一些实施方案中，使用基准标记来鉴定靶组织的位置。在一些实施例中，眼睛被保持并且与系统对准。在一些实施例中，设备沿着眼睛的轴线的对准内部的过度运动自动关闭。在一些实施例中，描述了放射外科手术与其他治疗组合使用的放射治疗疗法，并且可以在其它治疗之前，之前或之后随同伴随地递送。

17. 发明申请

WO2007114905A3 PERICARDIAL INSERTS AND METHODS OF USE 审中-公开
公开(公告)号：WO2007114905A3
公开(公告)日：2007-10-11
申请号：PCT/US2007/008184
申请日：2007-03-30
申请人： GEM BIOSYSTEMS, INC. , GERTNER, Michael
发明人： GERTNER, Michael
IPC分类号： A61M1/10
摘要： Devices, systems and methods are provided which are capable of applying pressure and constraint to the heart and use the pericardium to assist in the application of the pressure and force to the heart.

18. 发明申请

WO2006049725A3 SURGICAL SYSTEMS AND DEVICES TO ENHANCE GASTRIC RESTRICTION THERAPIES 审中-公开
标题翻译：手术系统和装置，以加强胃限制治疗
公开(公告)号：WO2006049725A3
公开(公告)日：2007-06-14
申请号：PCT/US2005033683
申请日：2005-09-19
申请人： MINIMUS SURGICAL SYSTEMS , GERTNER MICHAEL
发明人： GERTNER MICHAEL
IPC分类号： A61B19/00 , A61F2/04
CPC分类号： A61B17/0469 , A61B17/00234 , A61B17/0218 , A61B17/0401 , A61B17/0487 , A61B17/1114 , A61B17/29 , A61B17/3417 , A61B2017/00022 , A61B2017/00827 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0462 , A61B2017/0464 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/1135 , A61F5/0083 , A61F2002/044 , A61N1/36007
摘要： Methods and devices to perform gastroplasty procedures. In some embodiments, gastroplasty devices and methods are enhanced by feedback control though sensors which reside on or near the device. In some embodiments, an extragastric device is used to create a satiety in a patient. In some embodiments, a band device is the restriction device and in some embodiments a transgastric fastening assembly is the restriction device.
摘要翻译：进行胃成形术的方法和装置。在一些实施例中，通过位于设备上或附近的传感器的反馈控制来增强胃成形术装置和方法。在一些实施例中，使用胃外装置来产生患者的饱腹感。在一些实施例中，带式装置是限制装置，并且在一些实施例中，经胃紧固组件是限制装置。

19. 发明申请

WO2006049725A2 SURGICAL SYSTEMS AND DEVICES TO ENHANCE GASTRIC RESTRICTION THERAPIES 审中-公开
标题翻译：手术系统和装置，以加强胃限制治疗
公开(公告)号：WO2006049725A2
公开(公告)日：2006-05-11
申请号：PCT/US2005/033683
申请日：2005-09-19
申请人： MINIMUS SURGICAL SYSTEMS , GERTNER, Michael
发明人： GERTNER, Michael
IPC分类号： A61B17/08
CPC分类号： A61B17/0469 , A61B17/00234 , A61B17/0218 , A61B17/0401 , A61B17/0487 , A61B17/1114 , A61B17/29 , A61B17/3417 , A61B2017/00022 , A61B2017/00827 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0462 , A61B2017/0464 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/1135 , A61F5/0083 , A61F2002/044 , A61N1/36007 , G06F19/00
摘要： Methods and devices to perform gastroplasty procedures. In some embodiments, gastroplasty devices and methods are enhanced by feedback control though sensors which reside on or near the device. In some embodiments, an extragastric device is used to create a satiety in a patient. In some embodiments, a band device is the restriction device and in some embodiments a transgastric fastening assembly is the restriction device.
摘要翻译：进行胃成形术的方法和装置。在一些实施例中，通过位于设备上或附近的传感器的反馈控制来增强胃成形术装置和方法。在一些实施例中，使用胃外装置来产生患者的饱腹感。在一些实施例中，带式装置是限制装置，并且在一些实施例中，经胃紧固组件是限制装置。

20. 发明申请

WO2012125172A1 ENERGETIC MODULATION OF NERVES 审中-公开
标题翻译：神经的能量调节
公开(公告)号：WO2012125172A1
公开(公告)日：2012-09-20
申请号：PCT/US2011/033337
申请日：2011-04-20
申请人： GERTNER, Michael , PEROZEK, David , ZHANG, Jimin , SABET, Arash , KONA MEDICAL, INC.
发明人： GERTNER, Michael , PEROZEK, David , ZHANG, Jimin , SABET, Arash
IPC分类号： A61N7/00
CPC分类号： A61N7/02 , A61B6/506 , A61B17/22012 , A61B2017/00106 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2090/374 , A61B2090/3762 , A61N2007/003 , A61N2007/0043 , A61N2007/0091 , A61N2007/0095
摘要： A system for applying high intensity ultrasound energy to a nerve surrounding an artery of a patient includes a piezoelectric array comprising a plurality of ultrasound elements, a controller configured to individually control a phasing of each of the ultrasound elements, a platform on which the ultrasound elements are coupled, wherein the platform is configured to support at least a part of the patient, a programmable generator configured to generate an output power for at least one of the ultrasound elements, and a programmable processor configured to process a signal transmitted from one of the ultrasound elements and reflected back from tissue, and determine a tissue characteristic based on the reflected signal.
摘要翻译：将高强度超声能量施加到患者动脉周围的神经的系统包括包括多个超声元件的压电阵列，被配置为单独地控制每个超声元件的定相的控制器，其中超声波元件耦合，其中所述平台被配置为支持所述患者的至少一部分，被配置为为所述超声波元件中的至少一个产生输出功率的可编程发生器，以及被配置为处理从所述超声波元件之一发送的信号的可编程处理器超声元件并从组织反射回来，并且基于反射信号确定组织特征。

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